58 results about "Peritoneal dialysate" patented technology

Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be eliminated by pre-contacting with the trapping agent. Further, it is possible to eliminate carbonyl compounds transferred from the blood to the peritoneal cavity of the patient during peritoneal dialysis treatment, by adding the trapping agent to the peritoneal dialysate or by circulating the fluid through a carbonyl compound-trapping cartridge. Intraperitoneal protein modification by carbonyl compounds is inhibited by the present invention, thereby sufficiently reducing peritoneal disorders associated with peritoneal dialysis treatment.

Systems and methods of generating peritoneal dialysate and using the peritoneal dialysate with an integrated cycler are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare peritoneal dialysate from source water and infuse the prepared peritoneal dialysate into a patient with an integrated cycler. Optional dialysate storage containers are provided for storage of the peritoneal dialysate prior to use.

It is intended to provide a safe and highly stable peritoneal dialysate which causes neither peritoneal membrane disorders nor peritoneal sclerosis in frequently repeated peritoneal dialysis treatment, can protect the residual renal functions in chronic renal failure and inhibit the progress of renal damage over a long period of time, and enables peritoneal dialysis treatment in a diabetic patient. A peritoneal dialysate which contains 0.05 to 3.5 w/v% of taurine and 0.1 to 6.5 w/v% of trehalose as osmotic agents and having a pH value regulated to 6.5 to 7.5.

The invention provides a preparation process of peritoneal dialysate with a physiologic pH value. The process comprises raw material proportioning and a preparation process. The process is characterized in that the preparation process comprises the following steps: adding fresh water for injection into a proportioning container; inputting glucose, sodium chloride, calcium chloride, and magnesium chloride in prescription amount; after stirring and dissolving, adding water for injection to full dose to prepare a liquid A; adding fresh water for injection into another proportioning container; inputting sodium lactate; after stirring and dissolving, adding water for injection to full dose to prepare a liquid B; after uniformly stirring; respectively adding a pH adjustor into the liquid A and the liquid B to adjust the liquid medicine to appropriate pH values; after pre-filtering and terminal-filtering, respectively filling the liquid A and the liquid B to two chambers of a double-chamber transfusion bag in volume ratio of 1:1; plugging; sterilizing by water bath; sterilizing to obtain the peritoneal dialysate with low glucose degradation products and the physiologic pH value, wherein the pH value of the mixture of the liquid A and the liquid B reaches 6.8-7.4.

A peritoneal dialyzer including: a catheter capable of injecting and discharging peritoneal dialysate in an abdominal cavity of a patient; a peritoneal dialysate circuit connected to the catheter; and a dialyzer provided in the peritoneal dialysate circuit, the dialyzer including a hemodialysate circuit connected so that peritoneal dialysate passing through the inside can come into contact with a hemodialysate via a hollow fiber membrane, characterized in that means capable of measuring an osmotic agent concentration in the peritoneal dialysate is provided on the peritoneal dialysate circuit on the side of the end at which the catheter is connected with respect to the dialyzer, and a mechanism for dehydrating the peritoneal dialysate according to the osmotic agent concentration measured by the aforementioned means is provided on the hemodialysate circuit, and a method of peritoneal dialysis using the peritoneal dialyzer.

The invention relates to systems and methods for sensing fluid characteristics of peritoneal dialysate infused into and removed from a patient during treatment. The systems and methods include sensors, processors, and flow paths for determining patient health based on the fluid characteristics of the peritoneal dialysate. The system can be a peritoneal dialysis cycler which can include an infusion line; an effluent line; at least one pump positioned in the infusion and/or effluent line; and at least one sensor fluidly connected to the effluent line. The sensor can be at least one of a flow sensor, an ion selective electrode, a pH sensor, a pressure sensor, a refractive index sensor, and a temperature sensor. The method can include infusing peritoneal dialysate through an infusion line; removing peritoneal dialysate through an effluent line; and determining at least one fluid characteristic of the peritoneal dialysate in the effluent line.

In peritoneal dialysis, a therapy for end stage renal disease patients, glucose has been used mainly as an osmotic agent in the dialysate. However due to the oxidation and decomposition of glucose, protein cross linking reaction progress to cause peritoneum sclerosis, resulting in cease of this therapy The present invention relates to the dialysate comprising protein cross linking suppressor(s) and/or protein cross linkage splitter(s) for the solution of the problem. Effective suppressors or splitters may be reductants, anti-oxidants, mercapto compounds, sulfide, hydrosulfide, salt of reductive sulfur oxyacid, thiourea and its derivatives, hydroxyl and/or carboxyl residue(s) containing cyclic compounds flavonoids, nitrogen containing heterocyclic compounds, hydrazyl compounds and uronic acid containing mucopoly-saccharides and the like. The dialysate is prepared by sterilizing the dialysate under high temperature and pressure separately from the suppressors and by adding the suppressors, that is sterilized separately, into the dialysate. By use of the dialysate in the present invention, peritoneal dialysis can keep on without suffering from problem,

Systems and methods of generating peritoneal dialysate are provided. The systems and methods use a water purification module, a sterilization module and concentrates to prepare a bolus of peritoneal dialysate from source water for use with an non-integrated cycler.

Methods, systems, and kits are provided for performing hemodialysis, hemodiafiltration, and peritoneal dialysis on a portable machine suitable for both clinical and home use. Peritoneal dialysate can be flowed into and out of the peritoneal cavity, and can also be regenerated within the system, without the need for introducing fresh dialysate. Common hardware and software can be utilized for both peritoneal dialysis and other forms of dialysis such as hemodialysis, hemofiltration, and hemodiafiltration, allowing for facile transition between different dialysis modes using the same dialysis machine.

The invention provides a peritoneal dialysis sterilization operation cabin. The cabin comprises a lower casing and an upper casing, one side of the bottom wall of the lower casing is vertically provided with a side plate, a plug clamping slot and a dialysate joint clamping slot are formed in the upper end of the side plate, the other side of the bottom wall of the the lower casing is provided witha first linear motor, a first linear motor shaft is parallel with the bottom wall of the lower casing and the side plate, a second linear motor is arranged on the first linear motor shaft, a second linear motor shaft is perpendicular to the first linear motor shaft, the end of the second linear motor shaft is provided with a bracket base, an abdominal pipe switch clamping slot is formed in the upper end of the bracket base, the abdominal pipe switch clamping slot and the side plate are spaced apart, the top wall of the upper casing is provided with an ultraviolet lamp, and the ultraviolet lamp is arranged above the side plate. The cabin has the advantages of achieving the function of automatic connection and disinfection of a peritoneal dialysis external tube and a peritoneal dialysate connecting tube, solving the problem of unnecessary bacterial contamination caused by the docking process of a peritoneal dialysis pipeline, and improving the safety of peritoneal dialysis.

The invention relates to a multifunctional digital display thermostat nursing platform. The multifunctional digital display thermostat nursing platform comprises a multifunctional digital display thermostat, an upper platform, and a medicine box, wherein a medicine box is arranged on the surface of the upper platform, the left end of the upper platform is connected with a lifting rod, a sterilizing lamp is arranged at the right end of the upper platform, a right storage drawer is arranged on the lower end surface of the upper platform, a left storage drawer is arranged on the left side of theright storage drawer, a middle platform is arranged on the lower end surface of the left storage drawer, themultifunctional digital display thermostat is arranged below the middle platform, a garbagecollection device is arranged below the multifunctional digital display thermostat, a peritoneal dialysate detection basin is arranged on the left side of the garbage collection device, the lower endsurface of the peritoneal dialysate detection basin is provided with a weighing scale, and the lower end surface of the weighing scale is provided with a bottom platform. Therefore, the multifunctional digital display thermostat nursing platform has the advantages of good safety, large storage capacity and comprehensive functions.

The invention relates to a low-alkali low-calcium peritoneal dialyzate composition which contains 15 amino acids serving as main components and does not contain glucose. The pH value is adjusted by THAM, so that the contact time between peritoneum and the glucose can be shortened; furthermore, the low-alkali low-calcium peritoneal dialyzate composition is more physiologic, so as to reduce irritation to the peritoneum. Meanwhile, the amino acid dialyzate does not contain the glucose, so that generation of GDP can be avoided.

The invention discloses an improved peritoneal dialysis device, which comprises a liquid medicine bag. An infusion tube is arranged below the liquid medicine bag; a dropper is arranged on infusion tube; a pulley type switch is arranged below the dropper; the infusion tube penetrates through the pulley type switch; a pipe clamp is arranged below the pulley type switch; the infusion tube also penetrates through the pipe clamp; a main pipe and a waste liquid pipe are arranged at the top end of the infusion tube; the infusion tube is connected with the main pipe and the waste liquid pipe in a Y-shaped pipe mode; a connector is arranged at the top end of the main pipe; a pipe clamp is also arranged on the waste liquid pipe; and a thermochromic disc is arranged below the waste liquid pipe and connected with a waste liquid bag. The peritoneal dialysis device can clearly observe the peritoneal dialysis liquid injection flow velocity; tube blockage is avoided; observation, control and scheme adjustment during peritoneal dialysis operation are facilitated; the liquid inlet amount of a peritoneal dialysis liquid is conveniently observed; peritoneal dialysis related specimens are convenientlyand accurately reserved; specimen data accuracy and sterility are improved; and with the arrangement of the thermochromic disc on the waste liquid pipe, whether a waste liquid is discharged or not canbe judged by observing discoloration.

A peritoneal dialysis catheter comprises a catheter body, a glucose monitoring probe and a strip-shaped liquid capsule. One end of the catheter body is a dialysis area, a plurality of dialysis holes are opened on the dialysis area, the other end of the catheter body is connected to an external dialysate bag, one end of the catheter body with the dialysis hole is connected with the glucose monitoring probe, the strip-shaped liquid capsule is disposed in an inner cavity of the catheter body, the length of the strip-shaped liquid capsule is not less than the length of the dialysis area on the catheter body, one end of the strip-shaped liquid capsule is provided with a liquid injection port, the liquid injection port is disposed at one end of the catheter body connected to the external dialysate bag, and a rubber plug is arranged at an opening of the liquid injection port. The advantage of the peritoneal dialysis catheter is that the peritoneal dialysis catheter does not drift and has goodsealing property, the dialysis hole is not blocked, and the glucose concentration of peritoneal dialysate can be monitored in real time.

PERITONEAL DIALYSATE PURITY CONTROL SYSTEM A purity control system for use in peritoneal dialysis, the purity and control system comprising: a first fluid line fluidly connected to a peritoneal dialysate generation system and a first ultrafilter; a second fluid line fluidly connecting the first ultrafilter to a second ultrafilter; the peritoneal dialysate generation system comprising at least a water source, an osmotic agent source, an ion concentrate source, and a water purification module fluidly connected to a peritoneal dialysate generation flow path.

The invention relates to the technical field of liquid medicine preparation equipment, in particular to a peritoneal dialysis liquid supply system, which comprises a two-stage reverse osmosis water treatment system, a peritoneal dialysis liquid preparation system and a peritoneal dialysis treatment control system. The two-stage reverse osmosis water treatment system comprises a water storage device, the water storage device comprises a water storage barrel, a water delivery pipe and a precision filter; the water storage barrel is also provided with an outflow pipe, and the outflow pipe is provided with a first water pump; the peritoneal dialysis liquid preparation system comprises a medicine preparation box; the peritoneal dialysis treatment control system comprises a second water pump arranged on a fixed pipe, and a Y-shaped pipe is arranged at the water outlet end of the second water pump. According to the invention, changing a liquid medicine bag repeatedly is not required, and theprobability for infecting with peritonitis can be reduced; in addition, carrying can be facilitated, labor is saved, and certain convenience is brought to users.