38 results about "Peritoneal dialysis solutions" patented technology

The invention relates to the technical field of peritoneal dialysis monitoring, and discloses a dynamic weighing and data fusion peritoneal dialysis solution balance monitoring system and method. The system comprises a dynamic weighing module, a multi-source data acquisition module, a data fusion processing module, a balance monitoring module and an early warning output module. The dynamic weighing module collects dialysate input and discharge amount in real time and generates weight data; the multi-source data acquisition module is used for acquiring dialysate components, treatment time and physiological parameters of a patient; the data fusion processing module is used for fusing the data to generate dialysate balance characteristic data; the balance monitoring module is used for calculating the net ultrafiltration amount and the liquid balance state and identifying the risk of abnormal leakage or liquid retention; and the early warning output module generates early warning information when the risk is identified. The system does not need manual intervention, can collect and fuse multi-source data in real time, accurately judge the liquid balance state and give an early warning in time, and is suitable for hospital and home peritoneal dialysis scenes.

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

The present application relates to the technical field of automatic peritoneal dialysis machine, and particularly relates to a peritoneal dialysis fluid constant-temperature supply and flow self-adaptive regulation and control system; comprising: a liquid supply driving module, a non-contact end heating module, a multi-dimensional signal sensing module and a temperature-pressure coupling multi-state collaborative control module; the present application introduces a non-contact electromagnetic resonance end heating structure and a temperature-pressure coupling multi-state collaborative control algorithm, on the one hand, uses air gap and high-frequency electromagnetic eddy current to realize safe endogenous heat of dialysis fluid in the pipeline, effectively avoids the risk of local thermal deformation and plasticizer precipitation of the pipeline caused by traditional contact heating, improves the biological safety of fluid infusion, constructs a feedforward defense mechanism based on the change rate of end temperature, and through extraction of the dynamic amplitude and static component of the hydraulic waveform, realizes accurate identification of cold stimulation spasm, regular physiological disturbance and pipeline mechanical obstruction, and after diagnosing mechanical obstruction, actively drives the stepping motor to perform reverse backflushing action.

The utility model relates to a peritoneal dialysis solution sample transport box, which comprises a box body, a thermal insulation layer, a refrigeration device and a sealing cover, the box body is provided with a containing cavity used for containing a peritoneal dialysis solution sample, and the thermal insulation layer wraps the outer wall of the box body and is used for blocking external high temperature. The refrigeration device is arranged in the containing cavity and comprises a shell, a power box, a semiconductor refrigeration sheet and a cooling fin, the shell is installed in the box body, the semiconductor refrigeration sheet and the cooling fin are connected with the power box through wires, an installation hole is formed in the top of the shell, and one side of the cooling fin is inserted into the installation hole and fixedly connected with the shell; the other side clings to the hot surface of the semiconductor chilling plate; the sealing cover is detachably connected with the box body and used for sealing the containing cavity. The temperature in the box body is reduced by utilizing the refrigerating device, so that the peritoneal dialysis solution sample is refrigerated, the deterioration time of the peritoneal dialysis solution sample is delayed, and the accuracy of a detection result is improved.

The present application belongs to the technical field of packaging materials, and particularly relates to a peritoneal dialysis solution bag. The peritoneal dialysis solution bag comprises, from inside to outside, an inner layer, a heat preservation layer and an outer layer. The heat preservation layer is prepared from hollow fibers. The hollow fibers are obtained by spinning raw materials including chitosan, silk fibroin and hydroxyapatite. The prepared peritoneal dialysis solution bag has good heat preservation performance and barrier performance.

The utility model relates to the technical field of medical instruments, in particular to a bag for peritoneal dialysis fluid, which comprises a storage unit, an infusion unit and a control unit. The short pipe is provided with grooves and protrusions, the protrusions are integrally arranged on the upper side and the lower side of the short pipe respectively, and the grooves are formed in the left side and the right side of the short pipe respectively; the diversion unit comprises a first diversion tube and a second diversion tube, the first diversion tube is fixedly connected with the dialysis bag, and one end of the second diversion tube is fixedly connected with a short tube; the fastening and sealing unit comprises a fastening part and a sealing part, the fastening part is arranged at one end of the second flow guide pipe, the short pipe is arranged in the fastening part, and the sealing part is rotationally connected with the fastening part. Therefore, the short pipe is protected from being influenced by a humid environment or moisture, and the risk of infection is reduced.

A peritoneal dialysis fluid generation system including water purification equipment configured to provide purified water; a presterilized tubing set including a container for storing peritoneal dialysis fluid; at least one glucose or buffer concentrate; and a hemodialysis machine in fluid communication with the water purification equipment, the hemodialysis machine including at least one mixing pump for mixing the at least one glucose or buffer concentrate with the purified water to form peritoneal dialysis fluid, a dialysis fluid pump for delivering the peritoneal dialysis fluid to the container, and a control unit configured to control the at least one mixing pump to form the peritoneal dialysis fluid and the dialysis fluid pump to deliver the peritoneal dialysis fluid to the container.

The application provides application of circ-0007527 as a target in screening of drugs for treating peritoneal dialysis related peritoneal fibrosis. The application also provides application of an inhibitor of circ-0007527 in preparation of a drug for treating peritoneal dialysis related peritoneal fibrosis. In a mouse peritoneal fibrosis model induced by high glucose peritoneal dialysis solution, circRNA expressed in peritoneal tissues is screened, and after bioinformatics analysis, it is found that the differential expression amount of circ-0007527 in the fibrotic peritoneal tissue is the highest, and the high expression of circ-0007527 in the fibrotic peritoneal tissue is verified by real-time fluorescent quantitative PCR. Further in-vitro cell experiments find that down-regulation of the expression of circ-0007527 can significantly inhibit peritoneal mesothelial cell phenotype transformation, proliferation and apoptosis, and thus reduce peritoneal injury and delay peritoneal fibrosis progression.

The utility model provides a peritoneal dialysis solution zoning automatic conveying and heating constant-temperature box which comprises a constant-temperature box body, the interior of the constant-temperature box body is divided into a plurality of storage units, each storage unit is provided with a box door, conveying belts are oppositely and vertically arranged on the two sides of each storage unit respectively, and every two conveying belts located in the same storage unit form a group. A plurality of transverse blocking strips are arranged on the belt face of each conveying belt at intervals. The inside of the constant-temperature box body is divided into a plurality of storage units, peritoneal dialysis solutions of different brands or different concentrations can be placed in the different storage units, medical staff can directly take the peritoneal dialysis solutions from the storage units of the corresponding brands or concentrations when taking the peritoneal dialysis solutions, the possibility of taking mistakes is reduced, and the situation that the peritoneal dialysis solutions are disordered due to disordered placement is avoided; some peritoneal dialysis liquid can be stored for a long time to influence the use effect; the peritoneal dialysis device is divided into a plurality of areas to help medical staff to store and manage different peritoneal dialysis solutions, and on the other hand, the peritoneal dialysis solutions can be taken more accurately and orderly.

Dialysis fluid bags, as well as systems and methods involving dialysate bags, are disclosed herein. The dialysate bag comprises a first inlet / outlet port, a second inlet / outlet port, and an inner chamber containing peritoneal dialysate concentrate, the inner chamber being fluidically connected to the first inlet / outlet port and the second inlet / outlet port. The first inlet / outlet port and the second inlet / outlet port have an open state and a closed state, when open, each of the first inlet / outlet port and the second inlet / outlet port fluidically connects the inner chamber to the outside of the dialysate bag, and when closed, each of the first inlet / outlet port and the second inlet / outlet port fluidically separates the inner chamber from the outside of the dialysate bag.

A medical fluid generation system is disclosed. In an example, a peritoneal dialysis fluid generation system includes water purification equipment configured to provide purified water; a presterilized tubing set including a container for storing peritoneal dialysis fluid; at least one glucose or buffer concentrate; and a hemodialysis machine in fluid communication with the water purification equipment. The hemodialysis machine includes at least one mixing pump for mixing the at least one glucose or buffer concentrate with the purified water to form peritoneal dialysis fluid, a dialysis fluid pump for delivering the peritoneal dialysis fluid to the container, and a control unit configured to control the at least one mixing pump to form the peritoneal dialysis fluid and the dialysis fluid pump to deliver the peritoneal dialysis fluid to the container.

A peritoneal dialysis fluid generation system including water purification equipment configured to provide purified water; a presterilized tubing set including a container for storing peritoneal dialysis fluid; at least one glucose or buffer concentrate; and a hemodialysis machine in fluid communication with the water purification equipment. The hemodialysis machine includes at least one mixing pump for mixing the at least one glucose or buffer concentrate with the purified water to form peritoneal dialysis fluid, a dialysis fluid pump for delivering the peritoneal dialysis fluid to the container, and a control unit configured to control the at least one mixing pump to form the peritoneal dialysis fluid and the dialysis fluid pump to deliver the peritoneal dialysis fluid to the container.

Disclosed are example embodiments of a dialysis system that enables real-time preparation and delivery of peritoneal dialysis solution using a balancing chamber architecture. The system includes a water purification module configured to convert tap water into purified water meeting dialysis quality standards, and a mixing subsystem configured to combine the purified water with an osmotic agent, electrolytes, and a buffer to produce peritoneal dialysis solution on demand. A balancing chamber having a fresh side and a spent side is used to precisely meter delivery of the solution to a patient, with pressure applied to the spent side through a recirculation pathway. The system further includes fluid pathways for delivering the prepared solution to the patient and for removing fluid from the patient, under control of a controller that manages fluid flow and dosing accuracy. By integrating real-time solution preparation with balancing chamber-based fluid control, the system improves flexibility, reduces reliance on pre-mixed solutions, and enhances treatment efficiency.

The utility model relates to medical packaging material technical field, concretely to a peritoneal dialysis liquid high density polyethylene bag side edge sealing reinforcing structure, including HDPE bag body, the side edge sealing area of HDPE bag body is equipped with main heat seal line, the both sides of the along line position of main heat seal line are provided with a plurality of parallel support rib respectively, and still be equipped with auxiliary support band between support rib, and the outside of side edge sealing area of HDPE bag body is equipped with elastic buffer layer, support rib, auxiliary support band and elastic buffer layer jointly form the comprehensive enhancement sealing structure of HDPE bag body side edge area.

The utility model discloses peritoneal dialysis solution filling head cleaning equipment which comprises a cleaning bin, the top of the cleaning bin is rotationally connected with a turning cover plate through a hinge, and the outer wall of the bottom of the cleaning bin is fixedly connected with a drainage pipe; the overturning clamping assembly comprises a guide rail bin, and the inner wall of the guide rail bin is slidably connected with a first clamping bin and a second clamping bin; the washing assembly comprises a telescopic pipe and a washing spray head, the washing spray head is installed on the inner wall of the washing bin in a sliding mode, a servo motor drives a driving shaft to enable a filling head to turn over, the washing spray head capable of sliding up and down is combined, and it is ensured that each corner can be washed by washing liquid; compared with manual cleaning, stubborn stains and bacteria can be more efficiently removed, and the cleanliness of the filling head is guaranteed.

Systems, components, and methods are provided for a flexible, efficient system capable of producing customized dialysis fluid at the point of care. By enabling precise control over the solution's composition, the system significantly the customization, safety, and effectiveness of dialysis therapy. The placement of sensors and feedback mechanisms ensures accurate monitoring and adjustment of the solution's composition for dialysis fluid for patient treatment.

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

The invention relates to the technical field of medical supplies, in particular to a medical peritoneal dialysis waste liquid collecting and discharging machine which comprises a machine body, a waste liquid treatment assembly and a flushing assembly. A waste liquid inlet is formed in the side face of the machine body. The peritoneal dialysis waste liquid is mechanically treated, so that the peritoneal dialysis waste liquid is prevented from volatilizing in the air to cause bacterial pollution in the air and the environment; secondary pollution caused when patients and medical staff in hospitals treat the waste liquid is avoided; and a clean and tidy doctor-seeing and working environment is created for patients and medical staff.

Disclosed herein are dialysate pouches, and systems and methods relating to the dialysate pouches. The dialysate bag comprises a first liquid inlet and outlet port; a second liquid inlet / outlet port; the inner cavity is in fluid connection with the first liquid inlet and outlet port and the second liquid inlet and outlet port, each of the first liquid inlet and outlet port and the second liquid inlet and outlet port has an open state and a closed state, and when the first liquid inlet and outlet port is in the open state, the second liquid inlet and outlet port is in the closed state. Each of the first and second fluid inlet and outlet ports fluidly connects the lumen to an exterior of the dialysate bag when in a closed state, and each of the first and second fluid inlet and outlet ports fluidly isolates the lumen from the exterior of the dialysate bag when in a closed state.

The present disclosure generally relates to a device for analysing spent peritoneal dialysate from a peritoneal dialysis apparatus. The device comprises: a set of housings attachable to the peritoneal dialysis apparatus; a set of test components disposed in the housings, each test component and comprising one or more reagents for detecting one or more substances; and a set of fluidic conduits connected to the housings for communicating the dialysate from the peritoneal dialysis apparatus to the housings, wherein the test components are arranged for the reagents to react with the dialysate communicated to the housings and thereby detect the substances in the dialysate.

This utility model discloses a quantitative filling structure for peritoneal dialysis fluid, relating to the field of peritoneal dialysis fluid technology. It includes a support mechanism comprising a support frame, a positioning frame fixedly connected to the bottom of the inner cavity of the support frame, and a first cylinder fixedly connected to the surface of the positioning frame. A clamping plate is fixedly connected to the output end of the first cylinder. This utility model utilizes a defoaming storage mechanism. The storage tank integrates a vacuum pump and a piston assembly. By evacuating air, the internal pressure is reduced, causing bubbles to escape. A pressure sensor monitors in real time to ensure the defoaming effect. A second solenoid valve on the piston surface controls the liquid flow pressure to prevent the generation of new bubbles, ensuring bubble-free filling of the dialysis fluid from the source. Simultaneously, a flow sensor monitors the liquid flow rate in real time, linking with a third solenoid valve to precisely control the filling volume. Combined with the third cylinder adjusting the filling port height, a quantitative system of "dynamic monitoring + precise control" is formed, significantly reducing the dosage error rate of traditional structures.

The invention relates to the technical field of medicine packaging, and particularly discloses a neutral peritoneal dialysis bag and a preparation method thereof. According to the neutral peritoneal dialysis bag provided by the invention, the solution bag is detachably coated with the outer packaging bag, and the outer packaging bag is added with polyethylene glycol grafted nano carbon nitride and acetylene black, so that the outer packaging bag has excellent photothermal conversion performance and can provide lasting and stable heat support for the dialysis bag; therefore, the problem of solute precipitation of the neutral peritoneal dialysis solution caused by the temperature lower than 15 DEG C during transportation and storage is effectively prevented, the dialysis solution is kept in a uniform state, and the concentration stability of effective components is ensured. Besides, the raw materials of the outer packaging bag in the neutral peritoneal dialysis bag provided by the invention are common materials, the cost is low, and the large-scale production can be realized by matching with a simple preparation process.

The invention discloses a peritoneal dialysis constant-temperature box inventory management box and a system thereof, and belongs to the technical field of medical equipment management. The peritoneal dialysis liquid management box comprises a constant-temperature box body, wherein multiple layers of partition plates are arranged in the constant-temperature box body and used for storing different types of peritoneal The weight sensors are mounted at the bottom of each layer of partition plate and detect the total weight of each layer in real time; the embedded controller is used for storing single-bag peritoneal dialysis liquid standard weight data and a minimum inventory threshold value, and calculating the real-time inventory by dividing the total weight by the single-bag weight; a local alarm device; and a wireless communication module. The system further comprises an external terminal device which is used for deploying a visual instrument panel to display an inventory state, a historical record and a use trend. The identity recognition device records information of operators, and traceability of the whole process is achieved. The problems that traditional manual counting wastes time and labor, and replenishment is easy to omit are solved, the peritoneal dialysis liquid stockout event is effectively avoided through automatic monitoring and a multi-stage early warning mechanism, the medical service risk is reduced, and the intelligence and refinement level of inventory management is improved.

The utility model discloses a pressure leak detection device for producing and processing peritoneal dialysis solution, which relates to the technical field of peritoneal dialysis solution production and comprises a pressure detection box body, the pressure detection box body comprises a mounting box, the top of an inner cavity of the mounting box is provided with a peritoneal dialysis solution packaging bag hook, and the front surface of the mounting box is provided with a sealing door. After the packaging soft bag is hung on the hook, the air pump is used for pressurizing the interior of the sealed box body, then the first clamping plate and the second clamping plate abut against the two sides of the packaging bag, the pressure sensor is used for detecting the counter-acting force borne by the clamping plates, and when leakage holes exist in the packaging bag, peritoneal dialysis liquid is extruded out of the packaging bag through high pressure; when the packaging bag leaks, the packaging bag deforms, the size is reduced, the pressure detected by the pressure sensor changes accordingly, whether the packaging bag leaks or not can be accurately known according to the change of the pressure detected by the pressure sensor, and compared with conventional manual detection, the detection accuracy is higher, and use is more convenient.

The present application belongs to the technical field of aluminum salt determination of injection products in the pharmaceutical industry, and particularly relates to a method for determining aluminum salt in peritoneal dialysis fluid by using a fluorescence spectrophotometer. 3+ The complex formed in ethyl acetate has good stability and strong fluorescence intensity, and the sample is treated with concentrated hydrochloric acid and extracted with 1,1-dimethylpropanone (MIPK for short), so that the interference of transition metal impurity ions is eliminated. At the same time, the special determination parameters are specified, and the method after the research is verified well, and meets the aluminum salt inspection of peritoneal dialysis fluid products.

Systems, components, and methods are provided for a flexible, efficient system capable of producing customized dialysis fluid at the point of care. By enabling precise control over the solution's composition, the system significantly the customization, safety, and effectiveness of dialysis therapy. The placement of sensors and feedback mechanisms ensures accurate monitoring and adjustment of the solution's composition for dialysis fluid for patient treatment.

The utility model discloses lamp inspection equipment for peritoneal dialysis fluid, which comprises a workbench, a lamp tube, a lamp tube, a lamp tube, a lamp tube and a control system, wherein the inner wall of the middle part of the workbench is provided with a motor cabin; the detection table assembly comprises a detection rotary table, the top of the detection rotary table is fixedly provided with a pressure sensor, and the top of the pressure sensor is provided with an objective table; the lamp inspection assembly comprises a lamp holder, the height of the lamp holder can be adjusted in a lifting mode, and the lamp holder is rotationally connected with a lamp holder; the observation assembly comprises a magnifying lens and a magnifying lens support, and relates to the field of peritoneal dialysis solution lamp inspection equipment, the inspection rotary table is driven by the servo motor to stably rotate, it is ensured that all parts of a peritoneal dialysis solution package can be fully illuminated and inspected, and the situation of missing inspection caused by incomplete local observation is effectively avoided; and the pressure sensor monitors the packaging weight in real time, so that whether the packaging content of the peritoneal dialysis solution is normal or not can be conveniently found in time, and the operation convenience and practicability are improved.

The utility model relates to the technical field of medical treatment, and discloses a peritoneal dialysis solution constant-temperature pressurizing device which comprises a bag body, an observation window is arranged on one side of the bag body, a hanging rope is installed at the top end of the bag body, a heating cavity is formed in the rear end of the interior of the bag body, sliding rods are movably arranged in sliding holes, and the bag body is provided with a heating cavity. And one end of the sliding rod is fixed to the inner side wall of the bag cover, a connecting rod is fixed to one end of the pushing plate, and an extrusion plate is fixed to one end of the connecting rod. According to the constant-temperature pressurizing device, the second zipper, the cloth strips, the transparent plastic cloth and the like are arranged, so that when the constant-temperature pressurizing device is used, if dialysate bags with different quantities need to be placed in the constant-temperature pressurizing device, the transparent plastic cloth in the assemblies can be unfolded to increase the use space of the bag body; therefore, dialysate bags with different quantities can be placed in the bag body, and the practicability of the device is greatly improved.

Peritoneal dialysis (PD) containers having an injection stretch blow molded container body, an injection site, and a pop-up outlet valve are provided. The PD containers may be included in a PD therapy system which also includes a coil conduit, patient connector and drain bag. All of these components are made from polyolefin materials. In an alternate embodiment, a two piece outlet delivery device comprising an outlet base insert and a peelable tube may be used in place of the outlet pop-up valve. Kits for the PD therapy systems are also provided.

The present invention relates to the use of peritoneal dialysis solutions and methods of determining cell viability. The present invention provides the use of a peritoneal dialysis solution in the manufacture of a peritoneal dialysis solution for the treatment of end-stage renal disease and / or congestive heart failure, the peritoneal dialysis solution comprising: (c) a lactate buffered solution comprising about 1.5% w / v xylitol, about 0.5% w / v glucose and about 0.02% w / v L-carnitine, or (d) a lactate buffered solution comprising about 0.7% w / v xylitol, about 0.5% w / v glucose and about 0.02% w / v L-carnitine, wherein the peritoneal dialysis solution maintains or restores small solute and fluid removal and restores purification efficacy and / or ultrafiltration. The present invention also provides methods of determining cell viability.