53 results about "Peritoneal dialysis solutions" patented technology

The invention provides a peritoneal dialysis solution detection data intelligent analysis method based on visual identification, and the method comprises the steps: obtaining a to-be-identified test paper image, carrying out the test paper region segmentation and color correction of the test paper image, and carrying out the brightness equalization processing of a test paper detection region, and obtaining a processed test paper detection region; obtaining a standardized color feature vector of a test paper color development area from the test paper detection area; carrying out mapping matching on the standardized color feature vector and a standard colorimetric database to obtain a colorimetric matching value, carrying out color abnormality identification according to the colorimetric matching value, comparing the color abnormality with a preset abnormal value to obtain a test paper colorimetric analysis result, and carrying out self-adaptive correction on the test paper colorimetric analysis result with abnormality; and constructing a personalized colorimetric model according to the colorimetric matching value in combination with a historical colorimetric matching value, and performing health trend analysis and early warning.

The invention relates to the technical field of peritoneal dialysis monitoring, and discloses a dynamic weighing and data fusion peritoneal dialysis solution balance monitoring system and method. The system comprises a dynamic weighing module, a multi-source data acquisition module, a data fusion processing module, a balance monitoring module and an early warning output module. The dynamic weighing module collects dialysate input and discharge amount in real time and generates weight data; the multi-source data acquisition module is used for acquiring dialysate components, treatment time and physiological parameters of a patient; the data fusion processing module is used for fusing the data to generate dialysate balance characteristic data; the balance monitoring module is used for calculating the net ultrafiltration amount and the liquid balance state and identifying the risk of abnormal leakage or liquid retention; and the early warning output module generates early warning information when the risk is identified. The system does not need manual intervention, can collect and fuse multi-source data in real time, accurately judge the liquid balance state and give an early warning in time, and is suitable for hospital and home peritoneal dialysis scenes.

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

The present application relates to the technical field of automatic peritoneal dialysis machine, and particularly relates to a peritoneal dialysis fluid constant-temperature supply and flow self-adaptive regulation and control system; comprising: a liquid supply driving module, a non-contact end heating module, a multi-dimensional signal sensing module and a temperature-pressure coupling multi-state collaborative control module; the present application introduces a non-contact electromagnetic resonance end heating structure and a temperature-pressure coupling multi-state collaborative control algorithm, on the one hand, uses air gap and high-frequency electromagnetic eddy current to realize safe endogenous heat of dialysis fluid in the pipeline, effectively avoids the risk of local thermal deformation and plasticizer precipitation of the pipeline caused by traditional contact heating, improves the biological safety of fluid infusion, constructs a feedforward defense mechanism based on the change rate of end temperature, and through extraction of the dynamic amplitude and static component of the hydraulic waveform, realizes accurate identification of cold stimulation spasm, regular physiological disturbance and pipeline mechanical obstruction, and after diagnosing mechanical obstruction, actively drives the stepping motor to perform reverse backflushing action.

The utility model relates to a peritoneal dialysis solution sample transport box, which comprises a box body, a thermal insulation layer, a refrigeration device and a sealing cover, the box body is provided with a containing cavity used for containing a peritoneal dialysis solution sample, and the thermal insulation layer wraps the outer wall of the box body and is used for blocking external high temperature. The refrigeration device is arranged in the containing cavity and comprises a shell, a power box, a semiconductor refrigeration sheet and a cooling fin, the shell is installed in the box body, the semiconductor refrigeration sheet and the cooling fin are connected with the power box through wires, an installation hole is formed in the top of the shell, and one side of the cooling fin is inserted into the installation hole and fixedly connected with the shell; the other side clings to the hot surface of the semiconductor chilling plate; the sealing cover is detachably connected with the box body and used for sealing the containing cavity. The temperature in the box body is reduced by utilizing the refrigerating device, so that the peritoneal dialysis solution sample is refrigerated, the deterioration time of the peritoneal dialysis solution sample is delayed, and the accuracy of a detection result is improved.

The present application belongs to the technical field of packaging materials, and particularly relates to a peritoneal dialysis solution bag. The peritoneal dialysis solution bag comprises, from inside to outside, an inner layer, a heat preservation layer and an outer layer. The heat preservation layer is prepared from hollow fibers. The hollow fibers are obtained by spinning raw materials including chitosan, silk fibroin and hydroxyapatite. The prepared peritoneal dialysis solution bag has good heat preservation performance and barrier performance.

The utility model relates to the technical field of medical instruments, in particular to a bag for peritoneal dialysis fluid, which comprises a storage unit, an infusion unit and a control unit. The short pipe is provided with grooves and protrusions, the protrusions are integrally arranged on the upper side and the lower side of the short pipe respectively, and the grooves are formed in the left side and the right side of the short pipe respectively; the diversion unit comprises a first diversion tube and a second diversion tube, the first diversion tube is fixedly connected with the dialysis bag, and one end of the second diversion tube is fixedly connected with a short tube; the fastening and sealing unit comprises a fastening part and a sealing part, the fastening part is arranged at one end of the second flow guide pipe, the short pipe is arranged in the fastening part, and the sealing part is rotationally connected with the fastening part. Therefore, the short pipe is protected from being influenced by a humid environment or moisture, and the risk of infection is reduced.

A peritoneal dialysis fluid generation system including water purification equipment configured to provide purified water; a presterilized tubing set including a container for storing peritoneal dialysis fluid; at least one glucose or buffer concentrate; and a hemodialysis machine in fluid communication with the water purification equipment, the hemodialysis machine including at least one mixing pump for mixing the at least one glucose or buffer concentrate with the purified water to form peritoneal dialysis fluid, a dialysis fluid pump for delivering the peritoneal dialysis fluid to the container, and a control unit configured to control the at least one mixing pump to form the peritoneal dialysis fluid and the dialysis fluid pump to deliver the peritoneal dialysis fluid to the container.

The application provides application of circ-0007527 as a target in screening of drugs for treating peritoneal dialysis related peritoneal fibrosis. The application also provides application of an inhibitor of circ-0007527 in preparation of a drug for treating peritoneal dialysis related peritoneal fibrosis. In a mouse peritoneal fibrosis model induced by high glucose peritoneal dialysis solution, circRNA expressed in peritoneal tissues is screened, and after bioinformatics analysis, it is found that the differential expression amount of circ-0007527 in the fibrotic peritoneal tissue is the highest, and the high expression of circ-0007527 in the fibrotic peritoneal tissue is verified by real-time fluorescent quantitative PCR. Further in-vitro cell experiments find that down-regulation of the expression of circ-0007527 can significantly inhibit peritoneal mesothelial cell phenotype transformation, proliferation and apoptosis, and thus reduce peritoneal injury and delay peritoneal fibrosis progression.

The utility model provides a peritoneal dialysis solution zoning automatic conveying and heating constant-temperature box which comprises a constant-temperature box body, the interior of the constant-temperature box body is divided into a plurality of storage units, each storage unit is provided with a box door, conveying belts are oppositely and vertically arranged on the two sides of each storage unit respectively, and every two conveying belts located in the same storage unit form a group. A plurality of transverse blocking strips are arranged on the belt face of each conveying belt at intervals. The inside of the constant-temperature box body is divided into a plurality of storage units, peritoneal dialysis solutions of different brands or different concentrations can be placed in the different storage units, medical staff can directly take the peritoneal dialysis solutions from the storage units of the corresponding brands or concentrations when taking the peritoneal dialysis solutions, the possibility of taking mistakes is reduced, and the situation that the peritoneal dialysis solutions are disordered due to disordered placement is avoided; some peritoneal dialysis liquid can be stored for a long time to influence the use effect; the peritoneal dialysis device is divided into a plurality of areas to help medical staff to store and manage different peritoneal dialysis solutions, and on the other hand, the peritoneal dialysis solutions can be taken more accurately and orderly.

Dialysis fluid bags, as well as systems and methods involving dialysate bags, are disclosed herein. The dialysate bag comprises a first inlet / outlet port, a second inlet / outlet port, and an inner chamber containing peritoneal dialysate concentrate, the inner chamber being fluidically connected to the first inlet / outlet port and the second inlet / outlet port. The first inlet / outlet port and the second inlet / outlet port have an open state and a closed state, when open, each of the first inlet / outlet port and the second inlet / outlet port fluidically connects the inner chamber to the outside of the dialysate bag, and when closed, each of the first inlet / outlet port and the second inlet / outlet port fluidically separates the inner chamber from the outside of the dialysate bag.

A medical fluid generation system is disclosed. In an example, a peritoneal dialysis fluid generation system includes water purification equipment configured to provide purified water; a presterilized tubing set including a container for storing peritoneal dialysis fluid; at least one glucose or buffer concentrate; and a hemodialysis machine in fluid communication with the water purification equipment. The hemodialysis machine includes at least one mixing pump for mixing the at least one glucose or buffer concentrate with the purified water to form peritoneal dialysis fluid, a dialysis fluid pump for delivering the peritoneal dialysis fluid to the container, and a control unit configured to control the at least one mixing pump to form the peritoneal dialysis fluid and the dialysis fluid pump to deliver the peritoneal dialysis fluid to the container.

The utility model discloses an automatic bag placing device for peritoneal dialysis solution processing, which comprises a bottom support plate, a guide rail is mounted on the bottom support plate, a storage rack is slidably connected to the guide rail, a dialysis bag placing frame is arranged on the storage rack, a first electric push rod is arranged between the storage rack and the bottom support plate, and a second electric push rod is arranged between the storage rack and the bottom support plate. The bottom supporting plate is provided with a supporting column in a welded mode, the supporting column is provided with a cutting plate, and the cutting plate is slidably connected with a guide plate, the packaging bag arranging device relates to the technical field of packaging bag arranging, the guide plate is arranged on the cutting plate, so that cut objects are poured into the corresponding first sliding ways, and then the objects fall into the corresponding second sliding ways; and the dialysis bag placing frames are driven by the first electric push rods to move, so that articles fall into the dialysis bag placing areas of the corresponding columns, it is guaranteed that the breathable bags are placed in the dialysis bag placing areas one by one, automatic placing is achieved, and the production efficiency is improved.

A peritoneal dialysis fluid generation system including water purification equipment configured to provide purified water; a presterilized tubing set including a container for storing peritoneal dialysis fluid; at least one glucose or buffer concentrate; and a hemodialysis machine in fluid communication with the water purification equipment. The hemodialysis machine includes at least one mixing pump for mixing the at least one glucose or buffer concentrate with the purified water to form peritoneal dialysis fluid, a dialysis fluid pump for delivering the peritoneal dialysis fluid to the container, and a control unit configured to control the at least one mixing pump to form the peritoneal dialysis fluid and the dialysis fluid pump to deliver the peritoneal dialysis fluid to the container.

Disclosed are example embodiments of a dialysis system that enables real-time preparation and delivery of peritoneal dialysis solution using a balancing chamber architecture. The system includes a water purification module configured to convert tap water into purified water meeting dialysis quality standards, and a mixing subsystem configured to combine the purified water with an osmotic agent, electrolytes, and a buffer to produce peritoneal dialysis solution on demand. A balancing chamber having a fresh side and a spent side is used to precisely meter delivery of the solution to a patient, with pressure applied to the spent side through a recirculation pathway. The system further includes fluid pathways for delivering the prepared solution to the patient and for removing fluid from the patient, under control of a controller that manages fluid flow and dosing accuracy. By integrating real-time solution preparation with balancing chamber-based fluid control, the system improves flexibility, reduces reliance on pre-mixed solutions, and enhances treatment efficiency.

The present invention belongs to the field of medical technology, and in particular to a peritoneal dialysis fluid containing baicalein and its preparation method and use. The preparation method of the peritoneal dialysis fluid containing baicalein, comprises the following steps: step 1: baicalein is dissolved in DMSO and configured to baicalein-DMSO storage solution; step 2: baicalein-DMSO storage solution is added to the peritoneal dialysis fluid, and then supplemented with ultrasound, and the ultrasound is completed to obtain the peritoneal dialysis fluid containing baicalein. By the above-mentioned preparation method, baicalein is successfully dissolved in the peritoneal dialysis fluid and can be stably stored at room temperature, which provides a new strategy for developing novel peritoneal dialysis (PD) drugs to prevent and treat peritoneal fibrosis.

Peritoneal dialysis (PD) containers having an injection stretch blow molded container body, an injection site, and a pop-up outlet valve are provided. The PD containers may be included in a PD therapy system which also includes a coil conduit, patient connector and drain bag. All of these components are made from polyolefin materials. In an alternate embodiment, a two piece outlet delivery device comprising an outlet base insert and a peelable tube may be used in place of the outlet pop-up valve. Kits for the PD therapy systems are also provided.

The utility model relates to medical packaging material technical field, concretely to a peritoneal dialysis liquid high density polyethylene bag side edge sealing reinforcing structure, including HDPE bag body, the side edge sealing area of HDPE bag body is equipped with main heat seal line, the both sides of the along line position of main heat seal line are provided with a plurality of parallel support rib respectively, and still be equipped with auxiliary support band between support rib, and the outside of side edge sealing area of HDPE bag body is equipped with elastic buffer layer, support rib, auxiliary support band and elastic buffer layer jointly form the comprehensive enhancement sealing structure of HDPE bag body side edge area.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an icodextrin preparation for peritoneal dialysis and a preparation method of the icodextrin preparation. According to the icodextrin preparation for peritoneal dialysis provided by the invention, the first independent solution and the second independent solution are respectively prepared by adopting a double-chamber structure, and the taurine, the quercetin and the hyperbranched polyglycerol are added into the first independent solution; the icodextrin peritoneal dialysis solution effectively solves the risks of metabolic disorder and peritoneal injury caused by a traditional glucose dialysis solution and peritoneal fibrosis and pipeline blockage existing in an existing icodextrin dialysis solution, the stability of the icodextrin peritoneal dialysis solution is remarkably improved, the probability of adverse reactions is reduced, and the icodextrin peritoneal dialysis solution is excellent in viscosity resistance and osmotic pressure stability and can be used for preparing peritoneal dialysis solutions. The peritoneal dialysis solution can well replace the existing peritoneal dialysis solution, is simple in preparation process and good in repeatability, is easy to realize industrial mass production, and has relatively high popularization and application values in peritoneal dialysis treatment of patients with end-stage nephropathy.

The utility model belongs to the field of peritoneal dialysis solution production, and particularly relates to a peritoneal dialysis solution sterilization temperature monitoring probe bag which is characterized in that a liquid medicine bag, a drainage bag, a three-way valve and corresponding infusion tubes are all placed in an outer bag, and the liquid medicine bag is provided with a first infusion tube which is integrally formed; the end, located outside the liquid medicine bag, of the first infusion tube is provided with an infusion plug, the outer bag is provided with a first connector opposite to the infusion plug, the position of the first connector corresponds to the infusion plug and the first infusion tube, the end, located outside the outer bag, of the first connector is provided with a combined cover, and the outer bag is provided with a sealable exhaust pipe. The outer bag is connected with a sucking pump through an exhaust pipe; after the structure is adopted, the liquid medicine amount of each sterilization temperature monitoring probe bag and the residual air amount between the sterilization temperature monitoring probe bags and the outer bag interlayer are the same, so that the product sterilization effect at the cold point of the sterilization cabinet is uniform and stable, the temperature in the sterilization heating and cooling process is uniform, and the operation is convenient.

The utility model discloses peritoneal dialysis solution filling head cleaning equipment which comprises a cleaning bin, the top of the cleaning bin is rotationally connected with a turning cover plate through a hinge, and the outer wall of the bottom of the cleaning bin is fixedly connected with a drainage pipe; the overturning clamping assembly comprises a guide rail bin, and the inner wall of the guide rail bin is slidably connected with a first clamping bin and a second clamping bin; the washing assembly comprises a telescopic pipe and a washing spray head, the washing spray head is installed on the inner wall of the washing bin in a sliding mode, a servo motor drives a driving shaft to enable a filling head to turn over, the washing spray head capable of sliding up and down is combined, and it is ensured that each corner can be washed by washing liquid; compared with manual cleaning, stubborn stains and bacteria can be more efficiently removed, and the cleanliness of the filling head is guaranteed.

Systems, components, and methods are provided for a flexible, efficient system capable of producing customized dialysis fluid at the point of care. By enabling precise control over the solution's composition, the system significantly the customization, safety, and effectiveness of dialysis therapy. The placement of sensors and feedback mechanisms ensures accurate monitoring and adjustment of the solution's composition for dialysis fluid for patient treatment.

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

The invention relates to the technical field of medical supplies, in particular to a medical peritoneal dialysis waste liquid collecting and discharging machine which comprises a machine body, a waste liquid treatment assembly and a flushing assembly. A waste liquid inlet is formed in the side face of the machine body. The peritoneal dialysis waste liquid is mechanically treated, so that the peritoneal dialysis waste liquid is prevented from volatilizing in the air to cause bacterial pollution in the air and the environment; secondary pollution caused when patients and medical staff in hospitals treat the waste liquid is avoided; and a clean and tidy doctor-seeing and working environment is created for patients and medical staff.

Disclosed herein are dialysate pouches, and systems and methods relating to the dialysate pouches. The dialysate bag comprises a first liquid inlet and outlet port; a second liquid inlet / outlet port; the inner cavity is in fluid connection with the first liquid inlet and outlet port and the second liquid inlet and outlet port, each of the first liquid inlet and outlet port and the second liquid inlet and outlet port has an open state and a closed state, and when the first liquid inlet and outlet port is in the open state, the second liquid inlet and outlet port is in the closed state. Each of the first and second fluid inlet and outlet ports fluidly connects the lumen to an exterior of the dialysate bag when in a closed state, and each of the first and second fluid inlet and outlet ports fluidly isolates the lumen from the exterior of the dialysate bag when in a closed state.

The present disclosure generally relates to a device for analysing spent peritoneal dialysate from a peritoneal dialysis apparatus. The device comprises: a set of housings attachable to the peritoneal dialysis apparatus; a set of test components disposed in the housings, each test component and comprising one or more reagents for detecting one or more substances; and a set of fluidic conduits connected to the housings for communicating the dialysate from the peritoneal dialysis apparatus to the housings, wherein the test components are arranged for the reagents to react with the dialysate communicated to the housings and thereby detect the substances in the dialysate.

The utility model relates to the technical field of medical equipment, in particular to a peritoneal dialysis solution raw material preparation quantitative mixing device which comprises a solution preparation box, a solution separation plate is installed in the solution preparation box in a sliding mode, and a stirring part for stirring dialysis solution raw materials is installed on the solution preparation box. The left side of the top end of the outer wall of the liquid preparation box is communicated with a liquid inlet, and a weighing part for weighing peritoneal dialysis liquid raw materials is installed on the liquid inlet. When the peritoneal dialysis liquid metering device is used, the raw material metering barrel can be directly connected in the clamping frame in a lap joint mode, the liquid outlet is inserted into the liquid inlet, and therefore the peritoneal dialysis liquid metering device is convenient to use. The added raw materials can be metered through the scale marks on the raw material metering barrel, the raw materials can be discharged into the liquid preparation box by rotating the liquid discharge valve after metering is completed, and the raw material metering barrel can be directly taken down and cleaned after the raw material metering barrel is used for a period of time, so that the raw materials can be metered and prepared; and the raw material metering barrel can be quickly taken down to avoid pollution to follow-up raw materials due to long-time use.

The invention relates to the technical field of peritoneal dialysis, and discloses an automatic negative pressure peritoneal dialysis solution exchanger which comprises a machine body box, a first cavity is formed in the left side of an inner cavity of the machine body box, a second cavity is formed in the right side of the inner cavity of the machine body box, and a positioning box is slidably mounted on the lower end face of the machine body box. The exchange mechanisms are arranged on the left and right sides of the side wall of the positioning box; the top cover is detachably mounted on the upper end surface of the machine body box; the adjusting mechanism is arranged on the side wall of the top cover; and the heating mechanism is arranged in an inner cavity of the first cavity and an inner cavity of the second cavity. According to the peritoneal dialysis device, by arranging the exchange mechanism, dialysate can be stably pumped into the abdomen of a patient, drainage liquid can be pumped out at the same time, the safety performance of the patient during self dialysis is improved, by arranging the heating mechanism, the pumped dialysate can be heated, and the situation that the peritoneal dialysis effect is reduced due to the fact that too cold dialysate enters the abdomen of the patient is avoided.

This utility model discloses a quantitative filling structure for peritoneal dialysis fluid, relating to the field of peritoneal dialysis fluid technology. It includes a support mechanism comprising a support frame, a positioning frame fixedly connected to the bottom of the inner cavity of the support frame, and a first cylinder fixedly connected to the surface of the positioning frame. A clamping plate is fixedly connected to the output end of the first cylinder. This utility model utilizes a defoaming storage mechanism. The storage tank integrates a vacuum pump and a piston assembly. By evacuating air, the internal pressure is reduced, causing bubbles to escape. A pressure sensor monitors in real time to ensure the defoaming effect. A second solenoid valve on the piston surface controls the liquid flow pressure to prevent the generation of new bubbles, ensuring bubble-free filling of the dialysis fluid from the source. Simultaneously, a flow sensor monitors the liquid flow rate in real time, linking with a third solenoid valve to precisely control the filling volume. Combined with the third cylinder adjusting the filling port height, a quantitative system of "dynamic monitoring + precise control" is formed, significantly reducing the dosage error rate of traditional structures.

The invention relates to the technical field of medicine packaging, and particularly discloses a neutral peritoneal dialysis bag and a preparation method thereof. According to the neutral peritoneal dialysis bag provided by the invention, the solution bag is detachably coated with the outer packaging bag, and the outer packaging bag is added with polyethylene glycol grafted nano carbon nitride and acetylene black, so that the outer packaging bag has excellent photothermal conversion performance and can provide lasting and stable heat support for the dialysis bag; therefore, the problem of solute precipitation of the neutral peritoneal dialysis solution caused by the temperature lower than 15 DEG C during transportation and storage is effectively prevented, the dialysis solution is kept in a uniform state, and the concentration stability of effective components is ensured. Besides, the raw materials of the outer packaging bag in the neutral peritoneal dialysis bag provided by the invention are common materials, the cost is low, and the large-scale production can be realized by matching with a simple preparation process.