26 results about "Bioburden" patented technology

This application proposes a method for preparing gradient-pore structured biochar for soil remediation microbial loading, relating to the field of biomass resource utilization technology. The preparation method includes: pyrolyzing biomass raw materials at high temperature and then cooling to obtain biochar embryos; dissolving surfactants in water to prepare an impregnation solution; impregnating the biochar embryos in the impregnation solution and drying to obtain a mesoporous template; dispersing starch in water, heating, and adding the mesoporous template while stirring, reacting, and then cooling, settling, and drying to obtain a macroporous template; and calcining the macroporous template under an inert atmosphere using a gradient heating process to obtain biochar with a gradient-pore structure. This application, through synergistic regulation of raw material composition, pretreatment process, and programmed pyrolysis activation process, achieves for the first time a continuous gradient distribution of pore size from the outside to the inside ("macropore → mesopore → micropore") within a single biochar particle, significantly improving its performance as a microbial carrier.

Abstract The invention relates to a perioperative cobotic system designed to monitor, assess, and manage bioburden in real-time within operating room environments during surgical procedures and turnover phases. The system includes a mobile base equipped with a drive mechanism for maneuverability, a camera to capture image data, an actuator for camera movement, and a biosensor for direct bioburden assessment. Abstract for direct bioburden assessment. 20 26 21 41 22 10 A ug 2 02 6 A b s t r a c t 2 0 2 6 2 1 4 1 2 2 1 0 2 0 2 6 A u g

The invention discloses an ammonia direct oxidation denitrification device for water body remediation and a composite microbial carrier. The composite microbial carrier comprises an acetone slow-release inner core and a biological load shell, the acetone slow-release inner core is composed of an acetone-loaded solid adsorbent core and a calcium alginate gel wrapping layer, and precise and long-acting slow release of acetone is achieved through cooperation of adsorption immobilization and a gel diffusion barrier; the biological load shell is composed of polyurethane foam with a three-dimensional communicated macroporous structure, the inner core is wrapped in the shell, and the shell provides a three-dimensional space for microorganism attachment growth and AMAO reaction and delays outward diffusion of acetone. The device comprises a modular remediation unit assembled by a plurality of composite microbial carriers, the modular remediation unit is added into the ammonia nitrogen polluted water body, ammonia nitrogen in the water body is directly oxidized into nitrogen by the AMAO functional flora, and in-situ continuous denitrification is realized. The method solves the problems that the carbon source is easy to diffuse and lose and microorganisms are difficult to colonize, and has the advantages of high remediation efficiency, lasting effect and environmental friendliness.

Abstract The invention relates to a perioperative cobotic system designed to monitor, assess, and manage bioburden in real-time within operating room environments during surgical procedures and turnover phases. The system includes a mobile base equipped with a drive mechanism for maneuverability, a camera to capture image data, an actuator for camera movement, and a biosensor for direct bioburden assessment. Abstract assessment. 20 26 20 16 37 04 M ar 2 02 6 A b s t r a c t 2 0 2 6 2 0 1 6 3 7 0 4 M a r 2 0 2 6 a s s e s s m e n t .

The present disclosure provides, among other things, methods of drying porcine thyroid gland material and manufacturing DTE comprising vacuum drying porcine thyroid gland material in a way such that the temperature of the porcine thyroid gland material is maintained above a threshold temperature. Since applying vacuum, or reducing pressure, has a cooling effect on the porcine thyroid gland material, maintaining the porcine thyroid gland material above a threshold temperature can be achieved by gradually reducing pressure while simultaneously increasing the heat applied to the porcine thyroid gland material during the period of gradual pressure change. Such methods are advantageous in reducing bioburden (killing and impeding the growth of microorganisms) while maintaining therapeutic levels of thyroid hormones, as compared to certain methods of drying porcine thyroid gland material and / or manufacturing DTE known in the art.

The invention discloses a method for treating acid mine wastewater by using composite biochar, and relates to the technical field of sewage treatment. The invention discloses a method for adsorbing acid mine wastewater by using composite charcoal. The preparation method of the composite biochar comprises the following steps: performing alternate layer deposition on the surface of Fe-Al bimetallic oxide modified biochar to construct a chitosan layer and a carboxymethyl cellulose layer to obtain modified biochar; adsorbing acidophilic thiobacillus ferrooxidans by using the modified biochar to obtain microorganism-loaded biochar; inducing a hydroxyapatite mineralized membrane on the surface of the microorganism-loaded biochar to obtain acid-resistant microorganism-loaded biochar; and finally, embedding and fixing the acid-resistant microorganism loaded biochar to obtain the composite biochar. The composite biochar prepared by the invention can stably treat acid mine wastewater for a long time, and is convenient to recycle.

The invention relates to a method for treating medical waste through cooperation of spectrums and steam, and belongs to the technical field of medical waste treatment. According to the treatment method, the medical waste is treated through the cooperation of ultraviolet rays, near infrared rays and steam, the microorganism inactivation rate of the pet medical waste can be remarkably increased, the degradation rate of amoxicillin can be increased, biological membranes and chemical pollutants on the surfaces of the sharp instruments can be effectively removed, and the biological loading capacity of the treated sharp instruments is smaller than or equal to 10 CFU / g; meanwhile, compared with a traditional high-temperature treatment method, the treatment method has the advantages that the treatment period is shortened, energy consumption is reduced, and the method is suitable for on-site treatment of medical waste.

The present application relates to the technical field of radiation sterilization dose management, and particularly relates to a medical instrument radiation sterilization dose dynamic optimization system based on biological load analysis. The present application firstly obtains sterilization resistance according to the quantity difference of various bacteria before and after sterilization in all batches in the historical working period, combined with the corresponding radiation dose; further obtains comprehensive vitality combined with the seasonal similarity between working periods; further obtains biological load consistency and classifies the historical batches according to the similar characteristics of the quantity of all similar bacteria before sterilization and the comprehensive vitality between any two batches; further selects a reference batch, obtains a more reasonable initial radiation dose of the current working period according to the biological load consistency of the reference batch and the first batch at present, combined with the corresponding sterilization record, reduces the interference of seasonal activity difference of bacteria, reduces the number of subsequent repeated verification and correction, and improves the sterilization efficiency.

Disclosed embodiments relate to apparatuses and methods for applying negative pressure to a tissue site or skin site to prepare for a surgical operation. The apparatuses and methods can be used to increase blood flow at or near the tissue site. Therapeutic gas can also be applied to prepare the tissue site for the operation. Antimicrobial and antiseptic agents can also be applied to reduce the bioburden at the tissue site.

The application discloses modified biological filler and a preparation method and application thereof in the field of denitrification removal of nitrate, and relates to the technical field of denitrification. The preparation method comprises the following steps: immersing polyurethane foam in an amination modification solution containing N-(2-aminoethyl)-3-aminopropyl trimethoxysilane to obtain amin-modified polyurethane foam; and then immersing the amin-modified polyurethane foam in a bacterial solution containing denitrification bacteria to obtain a biological-loaded polyurethane foam. The polyurethane foam with developed pores is used as a carrier, and the surface of the polyurethane foam is modified by N-(2-aminoethyl)-3-aminopropyl trimethoxysilane, so that the adsorption amount and the binding strength of the denitrification bacteria can be improved. The modified biological filler loaded with the denitrification bacteria can shorten the acclimation period in the denitrification equipment, improve the denitrification rate in the initial stage, and improve the removal efficiency of the nitrate in wastewater.

The disclosure is directed at methods for reducing the bioburden of both particles comprising an active pharmaceutical ingredient (API) and the equipment used to process such particles.

The present disclosure provides, among other things, methods of drying porcine thyroid gland material and manufacturing DTE comprising vacuum drying porcine thyroid gland material in a way such that the temperature of the porcine thyroid gland material is maintained above a threshold temperature. Since applying vacuum, or reducing pressure, has a cooling effect on the porcine thyroid gland material, maintaining the porcine thyroid gland material above a threshold temperature can be achieved by gradually reducing pressure while simultaneously increasing the heat applied to the porcine thyroid gland material during the period of gradual pressure change. Such methods are advantageous in reducing bioburden (killing and impeding the growth of microorganisms) while maintaining therapeutic levels of thyroid hormones, as compared to certain methods of drying porcine thyroid gland material and / or manufacturing DTE known in the art.

A bandage modulates the moisture level of a healing wound and includes sensors for detecting, collecting, and reporting data for various wound variables. The bandage may include an antimicrobial agent to reduce the bioburden of microorganisms within the bandage.

The invention belongs to the technical field of saline-alkali land treatment, and particularly relates to a comprehensive improvement method for soda saline-alkali land through cooperation of modified ardealite and microorganism loaded biochar. The method comprises the following steps: cleaning ardealite by using an acidic waste liquid containing organic acid to obtain modified ardealite; mixing the modified ardealite, the saline-alkaline tolerant microorganism loaded biochar and granular aggregate to prepare a composite filler; vertical holes drilled in soda saline-alkali soil in advance are filled with the composite filler, and a reaction type permeation column is constructed; water is supplied to the reaction type permeation column, calcium ions and microbial metabolites dissolved in the column are driven to laterally permeate towards peripheral soil, and sodium ions on soil colloid are replaced. According to the invention, through system integration of'material modification 'and'spatial reconstruction', an'in-situ vertical-horizontal coupled biochemical reactor 'is constructed, and the soda saline-alkali soil is effectively improved.

The present invention concerns methods for processing and / or purification of a biological product involving multi-angle light scattering as analytical tool for process control. The methods of the invention apply multi-angle light scattering to detect the biological product, the presence of a bioburden or the functionality and / or integrity of a consumable employed in the method for processing and / or purification of the biological product. Further, the invention relates to systems for processing and / or purification of a biological product configured to perform the methods of the invention. Lastly, the invention concerns computer program products which can be used in the methods of the invention.

The invention relates to the technical field of medical instruments for the ophthalmology department, and particularly discloses a preparation method of a biodegradable patch for sclera reinforcement after the ophthalmology department, and the preparation method comprises the following steps: pretreating an extracellular matrix; the method comprises the following steps: firstly, carrying out virus inactivation on tissues or organs derived from animals, and carrying out antigen removal and degreasing treatment to obtain a biological load-free extracellular matrix; the pretreated extracellular matrixes are stacked in multiple layers and placed in a mold, an upper plane clamping plate and a lower plane clamping plate are used for applying pressure for fixing, and the pressure ranges from 10 kpa to 200 kpa; and drying with a mold to obtain the biodegradable patch. The limit load of the biodegradable patch obtained by the preparation method provided by the invention is 31.7-70.6 N, the elongation at break is 254.9-567.3%, and the biodegradable patch can meet the requirements on material strength and long-term stability in a sclera reinforcement operation after ophthalmology.

The disclosure is directed at methods for reducing the bioburden of both particles comprising an active pharmaceutical ingredient (API) and the equipment used to process such particles. A method of applying a coating to particles comprising an API comprises: (a) loading the particles into a chamber; (b) applying a vaporous or gaseous metal or metalloid precursor to the particles in the reactor by pulsing the vaporous or gaseous aluminium precursor into the reactor; (c) performing one or more pump-purge cycles using an inert gas; (d) applying a vaporous or gaseous oxidant to the particles in the reactor by pulsing the oxidant into the reactor; (e) performing one or more pump-purge cycles using an inert gas; (f) repeating steps (a)-(e) at least once to provide a metal oxide or metalloid oxide coating layer on the particles; and a sterilization step before step (a), between step (a) and step (b), and / or after step (f).

Methods for disinfecting or sterilizing aptamer-based sensors in preparation for application to an animal subject. Irradiation, including e-beam irradiation at sterilizing doses, is found to result in sensors having useful sensitivity to a target analyte.

One among various embodiments discloses a sealed nutrient cartridge for bioburden or sterility testing, comprising a transparent cover, a flexible side panel assembly coupled to the transparent cover, a transparent film assembly coupled to the flexible side panel providing a transparent film on an opposing side of the transparent cover, wherein the transparent cover, the flexible side panel assembly, and the transparent film assembly form an interior vessel for receiving a growth medium and a sample of a product.

The invention relates to a perioperative cobotic system designed to monitor, assess, and manage bioburden in real-time within operating room environments during surgical procedures and turnover phases. The system includes a mobile base equipped with a drive mechanism for maneuverability, a camera to capture image data, an actuator for camera movement, and a biosensor for direct bioburden assessment.

Bioburden analysis devices and related systems and methods are disclosed which utilize ultraviolet (UV) irradiation to enhance accuracy of results. A light source producing UV light is positioned along a passageway for a fluid flow upstream of a laser subsystem. The laser subsystem includes a laser which excites particulate within the fluid and a photo detector which measures fluorescence of the particulate within the fluid. By exposing the particulate to UV light prior to laser excitement, signal to noise ratio is increased, providing more accurate results.

The invention relates to the technical field of radiation sterilization dose management, in particular to a medical instrument radiation sterilization dose dynamic optimization system based on biological load analysis. The method comprises the following steps: firstly, obtaining sterilization resistance in a historical working period according to the quantity difference of various germs in all batches before and after sterilization and in combination with corresponding radiation doses; further combining seasonal similarity between the work cycles to obtain comprehensive vitality; further according to similar characteristics of the number and comprehensive vitality of all the similar germs between any two batches before sterilization, obtaining a biological load consistency degree, and classifying historical batches; a reference batch is further screened out, a more reasonable initial radiation dose of the current work period is obtained according to the biological load consistency of the reference batch and the current first batch in combination with a corresponding sterilization record, interference of seasonal activity difference of germs is reduced, the number of times of subsequent repeated verification and correction is reduced, and the sterilization efficiency is improved.

A treatment system, including a conveyor bed configured to transport a plurality of products; a brushing device located along the conveyor bed and having one or more brushes that include a first antimicrobial compound; a surface treatment device including a lamp configured to emit light of a peak wavelength directed toward a portion of the conveyor bed; and a coating device configured to deliver a coating mixture onto the plurality of products on the conveyor bed.

The invention belongs to the technical field of polluted water body remediation, and particularly relates to a binary or ternary composite reaction column based on in-situ synthesized maquinol as well as a preparation method and application of the binary or ternary composite reaction column. The two reaction columns are formed through a solution pretreatment-carrier filling-FeS in-situ synthesis-microbial loading technology, and the core difference lies in whether biochar is added into a carrier layer or not; a carrier layer of the'biochar-FeS-microorganism 'composite reaction column is a quartz sand-biochar mixed carrier, and an'adsorption-reduction-biodegradation' ternary synergistic system is formed; a carrier layer of the FeS-microorganism reaction column is made of pure quartz sand. The two reaction columns can continuously repair or relieve SMX-Cr (VI) composite polluted water, are used for solving the problems of low efficiency, easy material inactivation, microorganism loss, toxicity and the like of a single repair technology, are adaptive to various in-situ repair scenes such as underground water and surface runoff, and have the advantages of simple process, stable operation and easy large-scale application.

The invention relates to the technical field of pipeline automatic testing, in particular to a system and method for automatically testing the dispensing performance of a pipeline, the system comprises a pressure testing assembly, a pushing and injecting assembly and a control assembly, the pressure testing assembly is used for being connected with the pipeline to be tested and monitoring the pressure in the pipeline to be tested in real time; the pushing and injecting assembly is used for pushing and injecting gas to the pressure testing assembly; the control assembly is used for controlling the injection parameters of the injection assembly and reading the pressure value of the pressure testing assembly. According to the invention, the ten thousand-grade clean state and the controllable biological load state of the pipeline are not damaged, the subsequent drying process is not needed, and the test cost and the test time are reduced. Two procedures are not needed, so that the test time and the test cost are further saved; and whether the pipeline exceeds a qualified range is quantitatively judged.

The application discloses a method for treating acid mine wastewater by using composite biochar and relates to the technical field of wastewater treatment. The application discloses that the composite biochar is used for adsorbing and treating acid mine wastewater. The preparation method of the composite biochar comprises the following steps: Fe-Al bimetallic oxide is used to modify the surface of biochar, and a chitosan layer and a carboxymethyl cellulose layer are alternately deposited on the surface of the modified biochar to obtain modified biochar; acidophilic ferrous-oxidizing bacteria are adsorbed by using the modified biochar to obtain microbial-loaded biochar; the surface of the microbial-loaded biochar is induced to form a hydroxyapatite mineralization film to obtain acid-resistant microbial-loaded biochar; and finally, the acid-resistant microbial-loaded biochar is embedded and fixed to obtain the composite biochar. The composite biochar prepared in the application can stably treat acid mine wastewater for a long time, and is convenient to recycle and utilize.