The invention provides a tea substitute beverage, namely, salubrious and life-extension tea, and fills the blank of conventional nutritional food and tea substitute beverages. The tea substitute beverage is prepared by mixing the powder of fructus cannabis, jerusalem artichoke and xylitol, wherein the mass ratio of fructus cannabis to jerusalem artichoke to xylitol is 1 : 1 : 0.001. The tea substitute beverage has the advantages of simple preparation process, no pollutions, low cost, sufficient sources of the raw materials, convenience for eating, special health-care and anti-cancer effects, and the like. The tea substitute beverage can enhance human body metabolism functions, is beneficial to health, can prolong life, significantly reduces blood sugar, serum cholesterol and triglyceride, and can effectively provide auxiliary treatment for diabetes.