31 results about "Life extension" patented technology

The invention relates to the field of service life prolonging control, and discloses a reinforcement learning-based self-adaptive service life prolonging control method for a wind turbine generator, which is used for providing a reliable technical means for prolonging the service life of the wind turbine generator. Comprising the steps of collecting a unit operation state and key component health parameters, and generating multi-dimensional state information; establishing a damage evolution model, predicting the residual life and generating a health degree index; designing a multi-objective optimization strategy, and solving to generate a cooperative control instruction; after the instruction is executed, the model and the strategy are dynamically updated based on unit state feedback, and a closed-loop control system is formed. The service life of the wind turbine generator is effectively prolonged.

The vehicle of the present application includes a left-behind detection area which determines whether a person has been left behind in a vehicle or not, and a life extension control area which, if the left-behind detection area determines that the person has been left behind, causes a multitude of areas of the vehicle related to life extension to be activated progressively according to the time elapsed since the person was left behind.

The invention belongs to the technical field of power system and equipment management, and provides a system and a method for evaluating the life extension of an immediate electric energy meter based on anomaly evaluation, and the system comprises a data collection module which is used for collecting and obtaining the power utilization data of a transformer area group and the work operation data of the immediate electric energy meter; the batch division management module is used for carrying out batch division and management on the immediate electric energy meters based on the work operation data in combination with the immediate electric energy meter equipment parameter data; the anomaly analysis module is used for carrying out anomaly analysis on the electric energy meters which are divided in batches and are in time on the basis of an anomaly detection algorithm in combination with the working operation data to obtain an anomaly analysis result; and the life extension evaluation module is used for calculating a comprehensive life extension score by using a polynomial regression function according to the abnormal analysis result and the marketing data of the electric energy meter, and obtaining life extension evaluation results of the plurality of batches of immediate electric energy meters according to the comprehensive life extension score. According to the invention, online intelligent diagnosis, batch intelligent division, batch abnormity monitoring and batch quality evaluation can be realized.

By extending the lifespan of the refrigeration unit and reducing the frequency of replacement, the operating rate of the MRI system will be improved. [Solution] The cold head life extension mode is implemented. In the cold head life extension mode, the refrigerator's displayer is operated at a constant frequency lower than a predetermined upper frequency, regardless of the temperature of the superconducting coil, and the compressor inverter controls the drive frequency of the compressor drive unit according to the temperature of the superconducting coil.

The invention relates to the technical field of power system optimization operation, and particularly provides an energy storage and new energy power supply optimization scheduling method and device considering dynamic life loss, and the method comprises the steps: substituting power parameters of each power grid region into a pre-constructed energy storage and new energy power supply optimization scheduling model considering the dynamic life loss, and carrying out the solving, obtaining an optimization result of each power grid region; and based on the optimization result of each power grid region, obtaining an optimization scheduling scheme of each power grid region. According to the technical scheme provided by the invention, dual optimization of energy storage life prolonging and system economic operation is realized, and the new energy consumption capability and the power system regulation and control level can be remarkably improved.

The application relates to the field of life extension control, and discloses a wind turbine adaptive life extension control method based on reinforcement learning, which is used for providing reliable technical means for the life extension of a wind turbine. The method comprises the following steps: collecting the operation state of the wind turbine and key component health parameters, generating multi-dimensional state information; establishing a damage evolution model according to the multi-dimensional state information, predicting the residual life and generating a health degree index; designing a multi-objective optimization strategy, solving and generating a cooperative control instruction; and after the execution of the instruction, dynamically updating the model and the strategy based on the wind turbine state feedback, so as to form a closed-loop control system. The application effectively prolongs the life of the wind turbine.

This invention relates to the field of physics field calculation technology and discloses a multi-physics field coupling life assessment method for disconnecting switches. The method includes: real-time monitoring and deduction of the transient electromagnetic, thermal, and stress coupling states inside the switch to achieve accurate quantitative assessment of contact losses, aiming to promote efficient resource utilization and green management throughout the entire life cycle of power equipment. The method includes: calculating the rate of change of current based on transient current at adjacent sampling times; solving for local volumetric heat source density and radial temperature gradient by combining material properties; quantifying structural stress and frequency shift using thermoelastic theory; correcting the dynamic separation speed of the contacts through coupled electromagnetic repulsion; and finally calculating the vaporization and ablation loss volume based on the micro-arc energy density. This invention effectively improves the scientific nature of disconnecting switch maintenance decisions, reduces resource waste caused by premature maintenance, supports low-carbon energy conservation and green production in power systems, and achieves accurate life extension and efficient recycling of equipment.

The invention discloses a prediction method and system for prolonging human life years by health intervention service, and relates to the technical field of data processing, and the method comprises the steps: building a health prediction model, and according to all-cause mortality and disease morbidity data of different genders and age groups, calculating a health prediction model; predicting the death probability of the crowd of each age group, the number of years of survivors of each age group, the total number of years of survivors and the expected life; in combination with the prevalence condition of general population health risk factors and the relative risk degree of all-cause death, calculating the life number of individuals who carry out health intervention earnings on different risk factors, and calculating the overall health score of the current individual; evaluating the health condition of the current individual according to the total health score of the current individual, discovering key risk factors, and making an intervention scheme. The life expectancy of healthy or chronic disease patients can be measured and calculated, and the method is suitable for application scenes of health intervention service evaluation.

The invention discloses a method and system for evaluating the life extension of an oil and gas facility, and the method comprises the steps: disassembling the oil and gas facility to be evaluated, obtaining a plurality of subsystems to be evaluated, carrying out the three-element analysis of the subsystems to be evaluated, and selecting key factors affecting each subsystem; the influence degree of each subsystem on the whole oil and gas facility is analyzed, and on the basis, key factors of the corresponding subsystems are combined to determine key factor characteristic values; according to the structural feature detection data and the key factor feature value of each subsystem, determining the residual life of the subsystem; and according to the residual life of each subsystem and the life extension target of the whole oil and gas facility, determining a life extension measure of the subsystem which does not reach the life extension target. According to the method, the subsystems with different influence degrees can be evaluated respectively, the subsystems in bad states can be scientifically discriminated, and the aim of prolonging the service life of all the subsystems can be synchronously achieved by taking appropriate measures, so that the final recovery efficiency of oil and gas field development can be improved, and the maximization of oil and gas yield and economic benefits can be realized.

The invention belongs to the technical field of nuclear power plant aging life extension, and particularly relates to a performance supervision sample tree for a neutron absorber of a quadrilateral spent fuel storage grillwork. An upper pipe seat is arranged at the upper end of the quadrangular main body, a lower pipe seat is arranged at the lower end of the quadrangular main body, sample plate shelves are arranged on four sides of the quadrangular main body, 16 groups of sample plates are respectively placed on two groups of opposite sides, eight boron-aluminum plate sample plates are placed on eight groups on one side of each group of opposite sides, and eight groups of boron-aluminum coated sample plates are placed on the other side of each group of opposite sides; meanwhile, water-permeable holes are formed in the lower part of the sample plate shelf. The aging condition of a spent fuel storage grillwork neutron absorber material in a spent fuel pool is monitored, the actual performance of the neutron absorber material is evaluated, and the neutron absorber sample plate is put into a spent fuel storage grillwork and can be taken out regularly for detection.

The utility model provides a colloidal gold detection recording card which comprises a hard straight board card, a vertical sticking strip with a covering film and an information recording area, and the covering film realizes the antifouling protection of detection paper through the design of edge mucilage glue and a glue-free area. The recording card can prolong the storage life of detection paper, has strong traceability of detection data, and is suitable for medical detection, family self-test and other scenes.

This invention discloses a health management system and method for mining power electronic equipment, relating to the field of health management technology for mining power electronic equipment. The system includes a data acquisition unit, an aging model unit, an aging detection unit, and a life extension management unit. This invention determines the aging degree of a target power device by using actual operating voltage, collector current at actual turn-off time, actual turn-off time, actual thermistor resistance, junction temperature detection model, and turn-off time prediction model. Based on the aging degree of the target power device, it determines life extension management measures, thereby achieving the purpose of monitoring the aging degree of power electronic devices and applying corresponding life extension management.

The application discloses a kind of nuclear power plant metal component aging multidimensional detection and evaluation method and system, comprising: selecting the metal component of nuclear power plant to be detected and evaluated, according to the field environment and detection limit condition, using one or more methods of three kinds of ways of damaging, slightly damaging and non-destructive to multidimensional aging detection and evaluation of component, obtain the aging evaluation result of service metal component.The application realizes the multidimensional detection and evaluation of nuclear power plant metal component aging, masters its performance change and damage condition in service process, provides technical support for nuclear power plant aging management, life evaluation and life extension.

The invention relates to the technical field of mold life management, in particular to a mold life evaluation method and system, and the method comprises the steps: collecting mold multi-source data, and generating a structured multi-source data set after lightweight preprocessing; calculating an early warning proportion through curve fitting and a parameter fine tuning algorithm in combination with mold life characteristics and maintenance states, calculating life-increasing parameters through a constraint matching formula, rejecting low-efficiency data, and generating high-precision evaluation parameters; a double-time-domain prediction model is constructed, and prediction results of short-term early warning risks and medium-term life consumption trends are output; performing abnormity judgment by adopting a dynamic threshold algorithm, correcting core parameters through a data calibration mechanism according to a judgment result, generating an evaluation task adjustment instruction, and generating system optimization data according to an instruction execution result, model calibration information and mold operation data; and through the collaborative strategy model, the management strategies of different scenes are adapted. According to the scheme, the service life of the mold can be accurately controlled, and the production efficiency is improved.

The invention discloses an ackermania muciniphila strain and application of the ackermania muciniphila strain in preparation of a product for resisting weakness or prolonging healthy life, and particularly relates to the technical field of microorganisms, the ackermania muciniphila strain is preserved in China General Microbiological Culture Collection Center (CCTCC), the preservation number is CCTCC NO: 46390, the preservation date is April 15, 2025, and the preservation number is CCTCC NO: 46390. The preservation address is Institute of Microbiology, Chinese Academy of Sciences, No.3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing. The application refers to the application in preparation of anti-weakening products and health life prolonging products. The ackermansiella muciniphila has the effects of resisting weakness and prolonging the healthy life, has the application potential in preparation of products for relieving weakness and prolonging the healthy life, is low in preparation cost, high in preparation efficiency and small in side effect, and has a good industrial application prospect.

Embodiments provided herein, provide for polypeptides and molecules comprising a polypeptide having protease activity, which can be linked to a Fc molecule, or half-life extension moiety, pharmaceutical compositions comprising the same, and methods that can be used to treat disorders, such as immunoglobulin mediated disorders, including autoimmune disorders and diseases.

The invention belongs to the technical field of zinc extraction rotary kilns, and particularly relates to a zinc extraction rotary kiln head capable of preventing refractory materials from falling off and prolonging the service life of a barrel. Comprising a cylinder body, an outer cover body, a middle cover body and an inner cover body are erected outside the cylinder body, a necking opening is fixed to one end of the cylinder body, annular reinforcing ribs are welded to the necking opening, the cylinder body and the inner wall of the joint of the cylinder body and the necking opening, a plurality of axial reinforcing ribs are welded between the adjacent annular reinforcing ribs, and a plurality of protection plates are fixed to the outer wall of the joint of the cylinder body and the necking opening. A conical protective sleeve is fixed to the outer wall of the necking opening, a plurality of anchoring hooks are welded to the necking opening and the inner wall of the barrel, an annular air cooling pipe is erected on the outer side of the barrel, a plurality of air outlet holes are formed in the annular air cooling pipe, the air outlet directions of the air outlet holes face the barrel, and pouring materials are poured to the inner walls of the barrel and the necking opening. According to the invention, through the synergistic effect from multiple aspects, refractory falling is reduced, the service life of the barrel is prolonged, the overall operation efficiency of the rotary kiln is improved, and the maintenance cost and the production downtime are reduced.

Disclosed herein are fusion protein, comprising (a) at least one X1 domain comprising a half-life extension compound, including but not limited to a half-life extension polypeptide; (b) at least one X2 domain comprising an anionic block; (c) at least one X3 domain comprising a linker susceptible to cleavage at a site of disease, including but not limited to a microbial infection site or tumor site; and (d) at least one X4 domain comprising a therapeutic peptide; wherein the at least one X1, X2, X3, and X4 domains are covalently linked, and each X4 domain is linked to an X3 domain without an intervening X1 or X2 domain; compositions containing such fusion proteins, and methods for their use.

The present application relates to a kind of fatigue crack propagation life extension finite element analysis method, comprising the following steps: establishing three-dimensional solid model, simplifying three-dimensional solid model, obtaining fatigue crack tip stress distribution, obtaining fatigue crack propagation life.The process of obtaining fatigue crack propagation life includes measuring the length of metal structure fatigue crack, calculating the critical equivalent strain energy release rate of metal structure fatigue crack tip, calculating fatigue crack propagation life.The method of the present application applies virtual crack closure technique to the extended finite element method, achieves the purpose of simulating crack propagation without pre-specifying crack propagation path, thereby generating fine mesh at crack tip, saving the time required for modeling, reducing workload, and improving the accuracy of crack propagation life calculation.

This helps to estimate the occurrence of delamination, etc. [Solution] The estimation device identifies the operating time for which the bearing temperature and rotational speed belong to each of the eight ranges, and estimates the occurrence of delamination and other issues based on the operating time for each of the eight ranges and the modified rated life for each of the eight ranges.

The invention relates to the technical field of digital twinning, in particular to a digital twinning-based wind turbine generator full life cycle management system, which comprises a deformation parameter resolving module, a skeleton driving reconstruction module, a load damage calculation module, a health difference evaluation module and a balance control decision module. According to the method, the instantaneous curvature and the torsion rate are calculated by collecting cross section wavelength drift data, the dynamic bending posture of the flexible part in the space is reconstructed in real time, continuous tracking of stress circulation and a closed lag loop is achieved by combining pneumatic simulation and the residual peak-valley sequence stack technology, the accumulated damage degree of the part in the whole service cycle is accurately quantified, and the reliability of the part is improved. By analyzing the discrete deviation of individual damage relative to a group mean value, an asymmetric load distribution mechanism based on health state difference is established, the fatigue extension trend of high-damage parts is effectively relieved, premature failure caused by uneven load distribution is avoided, and life balance and collaborative life extension of key parts of a unit in the whole life cycle are achieved.

Embodiments provided herein, provide for polypeptides and molecules comprising a polypeptide having protease activity, which can be linked to a Fc molecule, or half-life extension moiety, pharmaceutical compositions comprising the same, and methods that can be used to treat disorders, such as immunoglobulin mediated disorders, including autoimmune disorders and diseases.

The invention relates to the technical field of power system relay protection, in particular to a decommissioning evaluation and life extension decision-making method for an overdue operation relay protection device and a readable storage medium. According to the invention, through constructing a multi-dimensional state data evaluation index system, comprehensive quantitative evaluation of the health state of the relay protection device is realized, and subjectivity of empirical judgment in traditional evaluation is avoided. Specifically, as a core mechanism in the assessment method, a hierarchical decision-making mechanism of a health state score H and a comprehensive risk score R is adopted. Through the two mechanisms, boundary conditions of decommissioning and life extension can be scientifically divided according to the actual condition of the device, so that the operation safety of a power grid is ensured, and the residual value of equipment is utilized to the greatest extent.

The invention relates to a braised pork seasoning as well as a preparation method, application and a verification method thereof, belongs to the technical field of food processing, and solves the problems that the traditional braised pork seasoning lacks healthy efficacy and is single in nutritional structure and local medicinal material resources are not fully utilized. According to the seasoning, 2-7 parts of star anise, 1.5-5 parts of cinnamon, 1-6 parts of pericarpium citri reticulatae, 0.25-1.5 parts of American ginseng, 0.25-1.5 parts of bay leaves, 2.5-10 parts of hawthorn and 7-20 parts of red dates serve as core anti-aging components, and the synergistic interaction of medicine and food is achieved through scientific compatibility. The method is mainly applied to cooking of braised pork in brown sauce, fruit fly experiments prove that the life can be remarkably prolonged, particularly, the life extension rate of female individuals under the concentration of 20 mg / mL reaches 37.55% or above, and the life extension rate can be further increased to 53.1% after process optimization.

Embodiments provided herein, provide for polypeptides and molecules comprising a polypeptide having protease activity, which can be linked to a Fc molecule, or half-life extension moiety, pharmaceutical compositions comprising the same, and methods that can be used to treat disorders, such as immunoglobulin mediated disorders, including autoimmune disorders and diseases.

This invention discloses a lung-nourishing and vital energy-strengthening traditional Chinese medicine composition containing Cordyceps sinensis, saffron, and Pteris vittata, and its preparation method, belonging to the field of traditional Chinese medicine preparation technology. The method includes: cryogenically treating Cordyceps sinensis and saffron at -25℃ to -10℃ and adjusting their water activity to 0.20 to 0.30; high-energy ultrafine pulverization at -5℃ to 5℃ to a D95 ≤ 50μm; supercritical solidification at 25 to 35 MPa and 35℃ to 45℃; and finally, encapsulation with Pteris vittata polysaccharide powder. This invention, through the triple coupling of cryogenic treatment, water activity, and supercritical pressure, induces the formation of stable molecular complex structures of active ingredients, solving the problems of easy degradation, low solubility, and poor bioavailability of adenosine. The composition obtained by this invention shows an increase in adenosine solubility of more than 5 times, an enzymatic half-life extension of more than 20 times, and anti-inflammatory efficacy in a lung injury model superior to a large compound of 12 herbs, demonstrating significant clinical application prospects.

The invention discloses application of Ectoin in preparation of a medicine for prolonging the service life, and belongs to the technical field of biology. Life experiments prove that the life of caenorhabditis elegans can be obviously prolonged by 25.8% by 5mM of Ectoine; 10 mM of Ectoine can obviously prolong the service life of caenorhabditis elegans, and the service life is prolonged by 43.4%; 15mM Ectoine can obviously prolong the service life of caenorhabditis elegans, and the service life is prolonged by 21.1%. The invention proves that Ectoin has an excellent effect of prolonging the service life, so that related products can be effectively developed on the basis of the medicine, and the Ectoin has wide application prospects and popularization values.

This estimation device identifies, for each of eight ranges, an operation time during which the bearing temperature and the rotation speed are within the range, and estimates the occurrence of peeling or the like on the basis of the operation time for each of the eight ranges and a corrected rated life for each of the eight ranges.

The invention discloses a transgenic tomato with high expression of a human longevity gene as well as a preparation method and application of the transgenic tomato. The transgenic tomato is obtained by introducing human longevity genes PF4, SIRT1 and Klotho into a tomato genome through a genetic engineering technology, the longevity genes in the transgenic tomato are expressed in fruits of the transgenic tomato, and the method is that the human longevity genes are introduced into the tomato through an agrobacterium-mediated transformation method; the invention also discloses application of the transgenic tomato in food and medicine, and application of the transgenic tomato in promoting longevity, delaying senescence process, improving human intelligence and physical strength and enhancing immunity. Through high expression of human longevity genes, the level of human health related genes in fruits can be remarkably improved, so that intelligence, physical strength and life are improved; transgenic tomatoes with high expression of human longevity genes can generate corresponding proteins in fruits, and the proteins have positive influence on health of the fruits of the tomatoes, namely intelligence enhancement, physical strength enhancement and life prolonging.

The present invention relates to a new IgG-degrading enzyme. Here, the inventors investigated whether the Fc fusion technology could be applied to a therapeutic enzyme of bacterial origin. Particularly, they developed IdeS-Fc fusion proteins as a divalent homodimer (IdeS-Fcdiv) or a monovalent heterodimer (IdeS-Fcmonov), in order to extend the IgG-depleting action of IdeS over time. Both IdeS-Fc efficiently separated monoclonal and polyclonal human IgG into F(ab')2 and Fc fragments, although with slower kinetics than their native counterpart. IdeS-Fcmonov exhibited a seven-fold half-life extension in vivo as compared to IdeS, and a significantly better residual cleavage of human IgG at later time points after injection. Their results provide the proof of concept for the use of an IdeS with extended IgG-hydrolyzing functions in vivo that could rapidly translate to the clinic. Thus, the present invention relates to an IgG-degrading enzyme-Fc fusion protein comprising at least one IgG-degrading enzyme fused to an Fc part of an antibody wherein the Fc part comprises at least one mutation.