The invention discloses a migratory Atlantic salmon factory-like artificial breeding method. The migratory Atlantic salmon factory-like artificial breeding method includes the eyed egg incubation stage, the mouth opening and feeding stage, the fry breeding stage and the silvering process stage. Eyed eggs are incubated in an incubator in an incubation room with running fresh water; in the mouth opening and feeding stage, Atlantic salmon fries are bred in an indoor breeding pond with running fresh water; in the fry breeding stage, indoor closed circulating fresh water breeding is performed; in the silvering process stage, indoor closed circulating fresh water breeding is performed, the silvering process includes the silvering period and the lighting recovery period, the silvering period of five weeks begins first, during the silvering period, it is bright for 12 hours and dark for 12 hours every day, then the lighting recovery period of fives weeks begins, and 24-hour lighting is performed every day during the lighting recovery period. In the breeding process, the Atlantic salmon fries are all incubated and bred indoors, so that incubation and breeding are free of weather influences, the incubation and breeding conditions can be manually controlled conveniently, large-scale breeding can be carried out, the breeding is stable, the survival rate of the fries is high, the fries are uniform in size, and high-density breeding can be achieved.