Peritoneal dialysis solution (lactate) (low calcium) composition

Abstract

The invention relates to a peritoneal dialysis solution (lactate) (low calcium) composition which comprises 1.5-4.0% of glucose, 0.5-0.6% of sodium chloride, 0.0001-0.0002% of calcium chloride, 0.00004-0.00006% of magnesium chloride and 0.4-0.5% of sodium lactate, and is characterized by further comprising 0.01-0.02% of sodium metabisulfite, sodium sulfite or sodium hydrogen sulfite.

Description

technical field [0001] The peritoneal dialysis fluid of the present invention and its preparation method. Background technique [0002] Compared with hemodialysis, peritoneal dialysis has the advantages of wide application range, high dialysis efficiency, good preservation of residual renal function, and high quality of life of patients. It occupies an increasingly important position in the replacement therapy of chronic renal failure. The key to successful peritoneal dialysis is a well-functioning peritoneum with ultrafiltration. However, due to the long-term nature of peritoneal dialysis treatment, the ultrafiltration performance of the peritoneum is often affected by various factors and changes during the treatment process, and this change is irreversible, which will eventually cause the loss of the peritoneal ultrafiltration function of the patient, making it impossible to perform Peritoneal dialysis treatment. The Chinese literature "Clinical and basic research on per...

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Problems solved by technology

The literature also pointed out that since glucose degradation products (GDPs) in peritoneal dialysis fluid can promote the expression of eNOS in endothelial cells but not the expression of AQP1, this effect of GDPs may be involved in the occurrence of ultrafiltration dysfunction during long-term peritoneal dialysis

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