93 results about "Peritoneal dialysis fluid" patented technology

An automatic exchanger apparatus for peritoneal dialysis fluids is provided having a dialysis fluid bag and a drained fluid bag and arranged for connecting and disconnecting between the end of a peritoneal dialysis circuit equipped with a branching point and the end of a tube extending from a patient to drain the waste dialysis fluid from the cavity of the patient and fill the peritoneal cavity of the patient with a fresh peritoneal dialysis fluid for exchange, and in particular comprises: means A, B, and C for carrying out respectively a step (A) of connecting the end of the patient side tube to the end of the peritoneal dialysis circuit, a step (B) of delivering and draining the waste fluid, and a step (C) of, disconnecting the two ends and connecting the end of the patient side tube to its shut-off member, arranged for carrying out their respective steps (A) and (C) automatically; and a controlling means for controlling the respectively means to execute their respectively steps in a sequence. The apparatus is simple in the construction while carrying out, with much ease, the connection and disconnection of the tubes and the exchange of the fluids including a waste and a fresh supply one, hence avoiding operational errors of the operator and minimizing the possibility of infection and contamination.

A method and a system for regenerating a body fluid, such as a peritoneal dialysis fluid. The body fluid is removed into an extracorporeal circuit comprising an electrofilter for removing charged ions from the body fluid, a nanofilter for removing large molecules, such as Dextran 40, and a reverse osmosis filter for concentrating the body fluid, for producing a synthetic urine to be discarded. The removed ions and large molecules are returned to the patient together with pure water from the reverse osmosis filter through an ultrafilter.

Peritoneal dialysis fluids and the use thereof for performing peritoneal dialysis are disclosed. The peritoneal dialysis fluid comprises a physiologically acceptable aqueous solution containing physiologically acceptable inorganic anions and cations and, as an osmotic agent, at least one sugar derivative, at concentrations sufficient for the removal of water and solutes from a patient by peritoneal dialysis. The sugar derivative is a compound of formulawherein each SG, which may be the same or different, represents a residue of a physiologically acceptable metabolizable sugar, SA represents a residue of a physiologically acceptable metabolizable sugar alcohol, n is from 1 to 4 andrepresents a glycoside linkage which is cleavable by an alpha-glycosidase enzyme.

The present disclosure relates to a wearable dialysis system and method for removing uremic waste metabolites and fluid from a patient suffering from renal disease. Uremic waste metabolites can be removed by a wearable peritoneal dialysis device (10) that regenerates the peritoneal dialysis solution without removing positively charged, essential ions from the solution and, consequently, the patient. Fluids can be removed. from the blood of the patient by an implantable fluid removing device (100). Fluids are delivered to the bladder and preferably removed from the body of the patient through urination. The wearable dialysis system may be operated continuously or; semi-continuously and be comfortably adapted to the body of the patient while allowing the patient to perform normal activities.

Disclosed is an apparatus having a heating function for hemodialysis, hemodiafiltration, hemofiltration or peritoneal dialysis, wherein the apparatus includes at least one of pipe for transferring at least one fluid of blood and dialsate, and a heating unit for heating at least one fluid of blood and dialsate, wherein the fluids to be heated by the heating unit are substances to be injected into human body; and the heating unit is arranged for measuring flow rates of the fluids to be heated, and injecting temperatures related with the flow rate to heat the fluids to be heated. The heating unit comprises: flow passages through which the fluids to be heated are flowed; a heater formed as a part of the flow passages, for generating heat; and a cover means including a first connection portion through which the fluids enter the flow passages, and a second connection portion through which the fluids come out from the flow passages. Present invention provides one effect in that blood having the same or nearly same temperature as that of human body can be injected into human body to prevent side effects caused by the dialysis and another effect in that blood can be heated effectively because the shapes of flow passages around the heater is deformed in improved manner.

A peritoneal dialysis (PD) system for infusing a volume of PD solution into a patient's peritoneal cavity in order to perform peritoneal dialysis on the patient includes a peritoneal cavity monitor (PCM) that measures this volume of fluid in the patient's peritoneal cavity by segmental bioimpedance spectroscopy (SBIS), to thereby determine an ultrafiltration volume of fluid in the patient's peritoneal cavity, and a switch, controlled by the PCM, for filling the patient's peritoneal cavity and draining the patient's peritoneal cavity when the ultrafiltration volume is unchanged over time, significantly decreased, or decreasing at a significant rate.

A method and a system for regenerating a body fluid, such as a peritoneal dialysis fluid. The body fluid is removed into an extracorporeal circuit comprising an electrofilter for removing charged ions from the body fluid, a nanofilter for removing large molecules, such as Dextran 40, and a reverse osmosis filter for concentrating the body fluid, for producing a synthetic urine to be discarded. The removed ions and large molecules are returned to the patient together with pure water from the reverse osmosis filter through an ultrafilter.

The present invention concerns a peritoneal dialysis fluid with enhanced ultrafiltration during the dialysis dwell period. According to the present invention this is achieved by a peritoneal dialysis fluid comprising sodium ions, osmotic agent and a buffer, characterised in that it comprises citrate at a level of 4 to 10 mM in a final solution ready for use.

The present invention relates to a fully automatic carbonate peritoneal dialysis device. The design element of the device is that the device comprises a peritoneal dialysate storage container, a dialysate input pump, a dialysate output pump, a dual-channel X-type polyester sleeve pipe, a blood leakage monitor and a bubble monitor. A dialysate weight sensor, a dialysate temperature sensor and a dialysate heating device are arranged in the peritoneal dialysate storage container. The dialysate input pump sends peritoneal dialysate into a human body abdominal cavity according to a set rate, and the dialysate output pump pumps the peritoneal dialysate out of the human body abdominal cavity according to the consistent rate of the dialysate input pump. One channel of the dual-channel X-type polyester sleeve pipe communicates with the dialysate input pump, and the other channel of the dual-channel X-type polyester sleeve pipe communicates with the dialysate output pump. The invention provides the fully automatic carbonate peritoneal dialysis device and a fully automatic carbonate peritoneal dialysis method.

The invention relates to a medical facility, in particular to a household automated peritoneal dialysis device. In the raw water treatment device of the facility, the water inlet of a multilayer filtration device is directly connected with a water source, the water outlet of a reverse osmosis device is connected with a peritoneal dialysis fluid mixer; the main body of a peritoneal dialysis fluid preparing device is a sealed metal box body, the metal box body is provided with interfaces which are connected with a plunger pump, a penetrant container, a peritoneal dialysis agent container, the peritoneal dialysis fluid mixer, an ultrafiltration device, a waste liquid container and an abdominal catheter through plunger valves; and the signal input interface of the ARM single chip microcomputer of a peritoneal dialysis automatic control system is connected with a treatment procedure module, a reparative treatment procedure module and a safety monitoring module respectively, and the signal output interface is connected with a power driver which is driven according to the commands of the ARM single chip microcomputer to control the plunger pump, the plunger valves, an electric heater, a solenoid valve and a sound and light alarm device. The invention integrates raw water treatment, peritoneal fluid preparation and automated dialysis so as to reduce medical cost and ensure safety and is suitable to be used in the basic units.

The invention relates to a testing system and related methods for detecting peritonitis or infection in peritoneal dialysate removed from a patient. The testing system can include a fluid sensor apparatus in a fluid line of a peritoneal dialysis cycler through which spent peritoneal dialysate can be pumped. The fluid sensor apparatus can detect one or more markers associated with peritonitis or infection.

The invention discloses a peritoneal dialysis solution product packaged by a non-PVC soft bag and a production method of the peritoneal dialysis solution product, and belongs to the technical field ofperitoneal dialysis. The peritoneal dialysis solution product packaged by the non-PVC soft bag comprises a packaging system which comprises a peritoneal dialysis solution bag, a medicine liquid guiding pipe and a waste liquid guiding pipe; a peritoneal dialysis solution is contained in the peritoneal dialysis solution bag; a sterile outer packaging bag is arranged outside the packaging system; the peritoneal dialysis solution bag is the non-PVC plastic infusion bag produced by a co-extruded film in a manner of dual films; a medicine adding pipe is connected to the infusion bag in a welded manner; an infusion pipe is further connected to the infusion bag in a welded manner; and the medicine liquid guiding pipe and the waste liquid guiding pipe can each be coiled into a circle with the diameter being 10-15 cm, and are each provided with a clamping device. According to the peritoneal dialysis solution product packaged by the non-PVC soft bag and the production method of the peritoneal dialysis solution product, the non-PVC plastic infusion bag is adopted for containing the peritoneal dialysis solution, and harm of a PVC packaging bag to a patient is avoided; and the infusion bag is connected with the medicine adding pipe and the infusion pipe both in the welded manner, and the phenomenon that when a soft bag made from a non-PVC film material is used for containing large-capacitypreparations, solution leakage happens easily is avoided.

An object of the present invention is to provide a chondroitin sulfate having a decreased molecular weight which has utilization as an inhibitor of peritoneal disorder caused by long-term use of a peritoneal dialysis fluid containing glucose or a polysaccharide thereof as an osmotic agent, utilization as an osmotic agent in a peritoneal dialysis fluid, and the like. The chondroitin sulfate having a decreased molecular weight of the present invention as a means for achieving the object is characterized by having a weight average molecular weight of from 1000 to 20000 and containing a constituent disaccharide unit represented by the following structural formula in an amount of from 65 o to 100% (molar ratio) of the total.-[4GlcAβ1-3GalNAc(6S)β1]-(wherein GlcA represents a D-glucuronic acid residue; GalNAc represents an N-acetyl-D-galactosamine residue; β1-3 represents a β1-3 glycosidic linkage; β1-4 represents a β1-4 glycosidic linkage; and (6S) indicates that position 6 of the monosaccharide residue is sulfated)

The invention relates to devices, systems, and methods for temperature regulation in generating peritoneal dialysate and using a peritoneal dialysis (PD) system. The system can use a heater and temperature sensors to regulate the temperature of fluid within the PD system.

A peritoneal dialysis system includes a base peritoneal dialysis system and a peritoneal dialysis fluid exchange system that operates independently of the base system. The base system includes a first cassette including a first patient line configured to be connected to a patient, and a PD cycler. The PD cycler receives the first cassette, and includes a pump that cooperates with the first cassette to deliver dialysate to and drain dialysate from a peritoneal cavity of the patient via the first patient line. The peritoneal dialysis fluid exchange system includes a second cassette including a second patient line configured to be connected to the patient and a fluid exchange device that receives the second cassette. The fluid exchange device includes a data exchange interface operable to transfer patient treatment data from the peritoneal dialysis fluid exchange system to the base peritoneal dialysis system.

The invention discloses a method for preventing a peritoneal dialysis tube from floating and a peritoneal dialysis tube with a fixed end, the tube including an abdominal cavity, an external dialysis tube is arranged inside the abdominal cavity, one end of the outer dialysis tube extends to the outside of the abdominal cavity, the inner wall of the outer dialysis tube is slidably inserted with an inner dialysis tube, one end of the inner dialysis tube extends to the outside of one end of the outer dialysis tube, one end of the inner dialysis tube is fixedly connected with a dialysis liquid bag,and one end of the outer dialysis tube and the inner dialysis tube are fixedly connected with an adjusting device. The method for preventing peritoneal dialysis tube from floating and the peritonealdialysis tube with fixed end have the advantages that: the position of the whole dialysis tube in the abdominal cavity is positioned, When in use, one hand holds the outer dialysis tube, and the otherhand pulls the outer part of the inner dialysis tube box, and the outer sleeved silica gel tube is extruded and protruded to the outer side, and the protruding silica gel tube contacts with the innerwall of the abdominal cavity, so as to further position the dialysis tube, thereby preventing the dialysis tube from having the problem of floating tube, and having the characteristics of accurate operation and positioning.

The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing only icodextrin and 0 to 2.34 g / L of sodium chloride, and an alkaline second liquid containing an alkaline pH regulator, in which the first liquid after sterilization has a pH of 5.0 to 5.5, the second liquid after sterilization has a pH of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a pH of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the pH of the peritoneal dialysis fluid is close to the physiological range.

The invention discloses a peritoneal dialysis operator and a method for peritoneal dialysis by virtue of the peritoneal dialysis operator. The peritoneal dialysis operator comprises an operating box, a control device as well as a disinfecting device and a heating device which are arranged inside the operating box, wherein operating holes are formed in left and right walls; each of the operating holes is in sealed connection to a latex glove, and the latex gloves are arranged inside the operating box; a first communicating hole and a second communicating hole are formed in front and rear walls, and a cover plate, by which the corresponding communicating hole is closed, is arranged outside each of the holes; the control device is connected to the disinfecting device and the heating device; and the control device is connected to a power connector. When the operator of the invention is used, an operating room is not required to be prepared, hand washing and a facial mask are avoided, and meanwhile, the operator is not limited by time and space and is available to operation anytime and anywhere. In addition, peritoneal infection relevant to peritoneal dialysis, caused by bacteria on nasal cavity, oral cavity, air and skin can be avoided to the greatest extent.

A method and a device for differentiation of substances in a body fluid, such as blood, plasma or used peritoneal dialysis fluid, for example for hemodialysis. The device has a compartment having several inlets for entering a body fluid, a transition fluid and a diffusion fluid for flowing parallel with each other in laminar flow layers with substantially equal flow velocities. The transition fluid layer is interposed between the body fluid layer and the diffusion fluid layer. The compartment further has a first outlet for removing the body fluid and the transition fluid and a second outlet for removing the diffusion fluid. Pumps are arranged for controlling the flow velocities so that a marker substance, such as albumin, will not diffuse from the body fluid layer across the transition layer, during the passage of the body fluid from the inlet to the outlet of the compartment.

A self-warming peritoneal dialysis solution bag (20) is provided that contains a peritoneal dialysis solution. The solution bag (20) can have an outer surface and a non-electric, warming patch (32, 34) adhered or affixed to the outer surface. The non-electric, warming patch (32, 34) can include an activatable agent that undergoes an exothermic reaction when activated. The warming patch (32, 34) can retain a sufficient amount of activatable agent to generate enough heat, upon activation, to warm the contents of the bag (20) to at least 95 Fahrenheit degrees. Warming patches that are separate from a peritoneal dialysis solution bag are also provided, as are kits for warming a peritoneal dialysis solution bag. Methods of warming a peritoneal dialysis solution bag with a non-electric, warming patch, are also provided.

The invention discloses a method for calculating a home continuous ambulatory peritoneal dialysis operation behavior. The method comprises the steps that firstly, an electronic weighing unit collects peritoneal dialysis fluid electronic weighing data, and the electronic weighing data is transmitted to an intelligent terminal; secondly, the intelligent terminal encrypts the electronic weighing data and transmits the electronic weighing data to a database; thirdly, the electronic weighing data transmitted by the intelligent terminal is received and decrypted by the database; fourthly, the database compares real-time data with reference data which is pre-stored in the database and has the same encoding standard, the difference value between the real-time data and the reference data is found out, and the difference value is converted to form a corresponding operation behavior integral, so that the home continuous ambulatory peritoneal dialysis operation behavior is calculated. The data of the operation behavior of a home CAPD patient can be recorded through the technology of the internet of things, and the operation behavior of the patient can be evaluated in an evaluation scoring mode.

The invention discloses a low-calcium lactate peritoneal dialysis fluid medicine composition. The low-calcium lactate peritoneal dialysis fluid medicine composition contains glucose, sodium chloride, calcium chloride, magnesium chloride, alkali, azulene sulfonate and salt or ester in terms of azulene sulfonate and water. The adverse effects of a peritoneal dialysis fluid on peritonea can be reduced.

Disclosed is an apparatus having a heating function for hemodialysis, hemodiafiltration, hemofiltration or peritoneal dialysis, wherein the apparatus includes at least one of pipe for transferring at least one fluid of blood and dialsate, and a heating unit for heating at least one fluid of blood and dialsate, wherein the fluids to be heated by the heating unit are substances to be injected into human body; and the heating unit is arranged for measuring flow rates of the fluids to be heated, and injecting temperatures related with the flow rate to heat the fluids to be heated. The heating unit comprises: flow passages through which the fluids to be heated are flowed; a heater formed as a part of the flow passages, for generating heat; and a cover means including a first connection portion through which the fluids enter the flow passages, and a second connection portion through which the fluids come out from the flow passages. Present invention provides one effect in that blood having the same or nearly same temperature as that of human body can be injected into human body to prevent side effects caused by the dialysis and another effect in that blood can be heated effectively because the shapes of flow passages around the heater is deformed in improved manner.

The invention relates to a peritoneal dialysis fluid (lactate) which comprises 1.5-4.25% of glucose, 0.4-0.7% of sodium chloride, 0.02-0.03% of calcium chloride, 0.01-0.02% of magnesium chloride and 0.4-0.6% of sodium lactate. The peritoneal dialysis fluid is characterized in that the pH of the peritoneal dialysis fluid is adjusted to be 7.3-7.7 through trihydroxymethyl aminomethane.

The invention provides a peritoneal dialysis liquid (lactate) composition and a preparation method thereof. The composition comprises the following components in percentage by weight: 1.5 to 4.25 percent of glucose, 0.4 to 0.7 percent of sodium chloride, 0.02 to 0.03 percent of calcium chloride, 0.01 to 0.02 percent of magnesium chloride, and 0.4 to 0.6 percent of sodium lactate. The preparation method is characterized by, after the peritoneal dialysis liquid is subpackaged, comprising the following steps of 1) heating the subpackaged peritoneal dialysis liquid to a temperature of 115 DEG C by adopting an autoclave sterilization method, and maintaining for 5 minutes; 2) treating the peritoneal dialysis liquid with ultrasonic wave with frequency between 20 and 50kHz and intensity between 5 and 20W / cm<2> while the peritoneal dialysis liquid is heated; and 3) stopping heating and ultrasonic wave treatment when the maintenance time of the step 1) is reached, and cooling to reduce the temperature.

Embodiments of the invention disclose a disposable peritoneal dialysis tube installation bin. The installation bin comprises a cylindrical docking chamber made of aseptic soft membranes, and aseptic soft membrane gloves arranged at the two ends of the docking chamber in a sealing manner, and the installation bin in formed through the surrounding of the docking chamber and the soft membrane gloves. The docking chamber is provided with an air inlet, a first guiding ring and a second guiding ring, wherein the air inlet connects the outside and the interior of the installation bin, and is provided with a filter core; a peritoneal dialysis tube stretches into the docking chamber through the first guiding ring; a dialysate tube stretches into the docking chamber through the second guiding ring; and the first guiding ring and the second guiding ring are in sealing states. The installation bin further comprises two circular frames and at least one third guiding ring. Force applying structures used for circularly opening the docking chamber are respectively arranged at the two ends of the docking chamber, and the circular frames are in detachable connection with the force applying structures. A sterilization device can stretch into the docking chamber through the third guiding ring, and the third guiding ring is in a sealing state. According to the embodiments, the peritoneal dialysis tube and the dialysate tube can be better prevented from being polluted by bacteria during the docking operation.

A diagnostic test apparatus comprises: an elongate housing defining a test strip holder containing a lateral flow test strip; a fluid sampling chamber provided with an opening connecting the fluid sampling chamber with the test strip holder; a viewing window in the elongate housing allowing reading of one or more portions of the lateral flow test strip; and a connector configured to couple the diagnostic test apparatus to a bulk source of fluid. The apparatus may be included in a kit of parts. The apparatus is useful for detecting peritonitis. The bulk source of fluid may be peritoneal dialysate. Various markers may be determined in the bulk source of fluid such as MMP8, IL-6, HNE, MMP2, MMP9, TIMP1, TIMP2, NGAL, A1AT, desmosine, fibrinogen, IL-8, calprotectin, fMLP, IL1 b, cystatin C, HSA, RBP4, SPD, MPO, sICAM and TNFa. Detection of the markers to indicate peritonitis may also inform treatment choices.

The invention provides an infusion device of a peritoneal dialysis machine, which comprises a liquid bag containing peritoneal dialysis solution, a liquid box and a waste liquid bag, wherein the liquid bag is arranged in the liquid box; an infusion tube and a drain tube are arranged between the liquid bag and the waste liquid bag; the liquid box is arranged above the abdomen of the human body, and the height difference between the liquid box and the abdomen of the human body is 500-800mm; and the waste liquid bag is arranged below the abdomen of the human body, and the height difference between the waste liquid bag and the abdomen of the human body is basically equal to the height from a bed surface to the ground. Because the peritoneal dialysis liquid bag is arranged in the position having a certain height to the abdomen of a patient, liquid flow pressure is formed through the height difference, thus the dialysis solution is led into an abdominal cavity; and similarly, after the osmotic exchange of the dialysis solution is finished, the waste liquid is discharged by utilizing the height difference between the waste liquid bag and the abdomen. The infusion device provided by the invention has the characteristics of simple structure design and safety in use.