4 results about "Abdominal pain" patented technology

This invention discloses a guanylate cyclase-C (GC-C) activating peptide and its applications, belonging to the field of bioactive peptide technology. The amino acid sequence of the GC-C activating peptide is PFPGPIPN. The GC-C activating peptide of this invention can significantly activate GC-C activity, increasing intracellular cGMP levels. Furthermore, the GC-C activating peptide of this invention can alleviate constipation and abdominal pain symptoms in mice, thereby effectively preventing or improving irritable bowel syndrome (IBS). Therefore, the GC-C activating peptide provided by this invention has advantages such as high activity, safety and non-toxicity, and good water solubility. It can be used as a candidate molecule for alternative or adjuvant drugs in the clinical treatment of IBS, and also as a health product or food to improve constipation or abdominal pain.

This invention discloses an intelligent constant-temperature pressure-controlled anti-reflux intestinal flushing device, belonging to the field of medical device technology. It includes a liquid storage and heating unit, a delivery and pressure control unit, a flushing and drainage unit, and a control unit. The liquid storage and heating unit is connected to the delivery and pressure control unit via a pipeline, and the other end of the delivery and pressure control unit is connected to the flushing and drainage unit via a pipeline. The control unit is electrically connected to the liquid storage and heating unit and the delivery and pressure control unit. This invention can prevent sudden pressure increases that could damage the intestinal mucosa through closed-loop pressure control, maintaining stable pressure within a safe range to avoid intestinal injury. It offers enhanced comfort due to constant temperature control, significantly reducing the incidence of abdominal pain and spasms. It is effective, achieving a high rate of intestinal cleansing while shortening operation time. It is convenient with one-button start and preset pressure levels; it is quick to assemble and disassemble, easy to clean, and can be operated by a single person. It is reliable, providing stable continuous operation and timely alarm response, meeting the requirements for high-frequency clinical use.

1. The name of the design product: warm uterus waistband. 2. The use of the design product: portable nursing supplies for relieving abdominal pain and cold discomfort during menstruation. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective drawing.

The present invention discloses use of hyocholic acid (HCA)-based bile acid species in the preparation of a medicament for the treatment of irritable bowel syndrome (IBS). It was discovered in the present invention that the content of HCA species in the feces of IBS-D patients treated with traditional Chinese medicine was significantly increased. Moreover, HCA species were significantly reduced in fecal samples of IBS-D patients compared with healthy controls. Further research revealed that HDCA and natural traditional Chinese medicine PULVIS FELLIS SUIS can reduce the peripheral serotonin level by inhibiting the activity of tryptophan hydroxylase 1, and significantly improve the symptoms of diarrhea and abdominal pain in TNBS-induced mice, indicating an application value of HCA species in treating IBS-D.