94 results about "Lavage fluid" patented technology

The invention relates to the technical field of pathogen detection, in particular to a primer probe combination and a kit for detecting various invasive fungi and application of the primer probe combination and the kit. According to the primer and probe combination provided by the invention, a digital PCR (Polymerase Chain Reaction) platform technology is utilized, so that the rapid, efficient, accurate, sensitive and high-specificity simultaneous quantitative detection of Aspergillus fumigatus, Aspergillus, Mucoriums, Cryptococcus and Pneumocystis jirovecii is realized. The rapid detection of the common invasive fungi in sputum, alveolar lavage fluid, urine, blood and other samples is realized, the detection process does not need culture, the detection period is short, the manpower is greatly reduced, and the detection efficiency is improved.

The invention relates to a bronchoalveolar lavage fluid rapid detection method based on a fluorescent staining technology and a corresponding detection device, and aims to improve the detection efficiency of alveolar lavage and sampling screening. The detection device comprises an endoscope assembly, a lavage fluid supply module, a recovery module and a control module. Wherein the recovery module is internally provided with an assembly used for adding a fluorescent coloring agent into the recovery liquid, the fluorescent coloring agent is injected into the recovery liquid in the recovery process of the lavage fluid according to needs, and an electromagnetic drive stirring mechanism is combined, so that dynamic and uniform mixing of the dyeing liquid and the lavage fluid is achieved. The control module automatically adjusts the injection amount, the mixing speed and the stirring duration of the coloring agent according to preset parameters or real-time detection data, and the dyeing reaction time in the operation process is remarkably saved.

The invention discloses a traumatic patient body cavity rewarming method and device based on double-orifice precise temperature control and a storage medium. According to the method, temperature control lavage fluid is synchronously conveyed through double cavities, body temperature and pressure data are collected in real time, parameters are dynamically adjusted, and efficient rewarming is achieved. The device comprises a main machine, a double-cavity rewarming catheter and detachable consumables, the double-cavity catheter comprises a bladder lavage cavity and a stomach tube rewarming cavity and is connected with the main machine through a spiral connector, and the heat exchange efficiency is improved through an internal spiral heat conduction structure; the host integrates an intelligent temperature control system and a double-pump driving and pressure monitoring module, and supports a touch screen operation and wound first-aid mode. The system may store and synchronize data to an external medical system. The scheme solves the problems of low rewarming efficiency, temperature control difference, complex operation and the like in the prior art, and is suitable for low-body-temperature treatment of traumatic patients.

The utility model discloses a double-cavity suction catheter and a pulmonary alveolar lavage device comprising the same. The catheter comprises a water injection pipe and a water suction pipe. A plurality of spray holes are formed in the circumferential surface of the water injection pipe, the far-end end surface of the water injection pipe is connected with the circumferential surface of the water suction pipe, the far-end end part of the water suction pipe is closer to the far-end side than the far-end end part of the water injection pipe, and the outer diameter of the far-end of the water suction pipe is smaller than that of the far-end of the water injection pipe. The lavage device can recover lavage fluid in the deeper airway and avoid retention of the lavage fluid in the body, and the lavage fluid in the trachea can be recovered through the water suction pipe while the lavage fluid is injected into the trachea through the water injection pipe for lavage.

The invention discloses an application of isothunberine or a pharmaceutically acceptable salt thereof in preparation of a medicine for preventing and / or treating asthma diseases. It is found that in an OVA-induced mouse asthma model, the isothunberine significantly reduces airway resistance excited by acetylcholine, improves inflammatory cell infiltration and airway mucus high secretion of asthma model mouse lung tissue, reduces the levels of lgE and OVA-lgE in serum and related inflammatory factors in alveolar lavage fluid, and has the effect of preventing and treating asthma. Therefore, the effect of treating asthma is achieved. Therefore, the isothunberine has the potential of preventing or treating the asthma, provides a new treatment mode for the treatment of the asthma, and has a wide application prospect.

The application provides an operating bed system, comprising: a flushing pump having a lavage tube for introducing lavage fluid into the body of a medical object and a recovery tube for recovering waste liquid generated by lavage; the liquid metering device is used for metering the amount of the lavage liquid flowing out of the lavage pipe and the amount of the waste liquid recovered by the recovery pipe; the bed body is provided with a carrying table for carrying a medical object, and the carrying table is provided with a confluence part which is used for collecting leaked liquid leaked to the carrying table and is provided with a through hole; the leaked liquid collecting device is communicated with the through hole and is used for collecting leaked liquid flowing out of the through hole; the leaked liquid metering device is used for metering the amount of the leaked liquid collected by the leaked liquid collecting device; and the processor is in signal connection with the liquid metering device and the leaked liquid metering device and is used for acquiring the lavage fluid amount, the waste liquid amount and the leaked liquid amount and determining the human body absorption amount based on the lavage fluid amount, the waste liquid amount and the leaked liquid amount. According to the method, the parameters required by the human body absorption amount can be automatically and timely measured and calculated, the safety risk can be reduced, and the user experience can be improved.

The invention discloses a pulmonary alveolar lavage device for children pneumonia patients, and relates to the technical field of medical instruments, the pulmonary alveolar lavage device comprises a lavage device and a suction pipe, the suction pipe is fixedly communicated with the lavage device, one end of the suction pipe far away from the lavage device is provided with a sealing assembly, the sealing assembly comprises a bearing box, and the bearing box is fixedly communicated with one end of the suction pipe far away from the lavage device. A long rod support is fixedly connected to the outer side wall of the bearing box. By means of continuous operation of the progressive assembly, follow-up full-filled collection bottles and pushing of the previous collection bottle, the full-filled collection bottles are arranged on the workbench in a linear array mode, the filling sequence of the collection bottles can be determined, follow-up detection and analysis are helped, and the accuracy and traceability of the detection result are ensured, for example, the detection efficiency is improved. When the lavage fluid is subjected to microbiological culture and analysis, the dynamic change of an illness state can be judged by knowing the perfusion sequence of the sample, and the change condition of pathogens in the lavage fluid at different stages can be observed.

The invention relates to application of a traditional Chinese medicine composition in preparation of a medicine for treating pneumonia, which is characterized in that the traditional Chinese medicine composition is prepared from gypsum, rehmannia, ophiopogon root, rhizoma anemarrhenae and achyranthes bidentata. The composition disclosed by the invention can be used for remarkably reducing the content of inflammatory factors of IL-6, IL-1beta and TNF-alpha in alveolar lavage fluid of a model rat with pneumonia caused by lipopolysaccharide, reducing the number of white blood cells and neutrophils of rat blood and increasing the percentage of lymphocytes and platelets, so that the traditional Chinese medicine composition has a relatively good treatment effect on pneumonia.

The utility model discloses a small animal alveolar lavage device which comprises an oxygen tank and a lavage fluid tank on the right side of the oxygen tank, a needle cylinder is arranged on the left side of the oxygen tank, a controller is fixedly connected to the outer wall of the right end of the needle cylinder, and a fluid outlet pipe is fixedly connected to the portion, close to the right side, of the outer wall of the lower end of the needle cylinder so that lavage fluid can be communicated with oxygen to be sprayed out. A liquid return pipe is arranged on the left side of the liquid outlet pipe to recycle used irrigation liquid, a waste liquid tank is arranged on the left side of the needle cylinder to collect waste liquid, a guide pipe c is arranged between the waste liquid tank and the needle cylinder to guide the moving direction of the waste liquid, and a guide pipe a is arranged between the oxygen tank and the needle cylinder to guide circulation of oxygen. A guide pipe b is arranged between the irrigation solution tank and the needle cylinder to guide irrigation solution to circulate, and by installing a temporary storage bubble, a handle, a threaded rod and a movable ring, waste liquid is prevented from dripping on the ground, so that the ground is prevented from being polluted, the time of the irrigation process is shortened, and the irrigation speed is increased.

The invention belongs to the technical field of biological medicine, and particularly discloses application of CCL28 as a biomarker and a therapeutic target in sepsis. The invention particularly relates to application of a CCL28 gene or a detection reagent for the expression quantity of the CCL28 gene in preparation of a kit for diagnosis or prognosis monitoring of sepsis. The expression of the novel immunomodulatory factor CCL28 in a sepsis patient is obviously improved, and the expression level of the novel immunomodulatory factor CCL28 is in obvious negative correlation with poor prognosis of sepsis. Through CLP induction of a sepsis mouse model, the invention finds that the expression level of CCL28 in sepsis mouse blood, abdominal cavity lavage fluid (PLF), liver and kidney is significantly increased. By adopting the recombinant CCL28 for treatment, the bacterial load in the mice with sepsis can be remarkably reduced, and the multi-organ injury of the mice with sepsis can be reduced, so that the survival rate of the mice with sepsis can be remarkably improved. In conclusion, the invention explores a novel immunomodulatory protein CCL28, and the novel immunomodulatory protein CCL28 not only can be used as a diagnosis and prognosis biomarker of sepsis, but also can be used as a novel target spot for treating sepsis.

The invention discloses a broncholung lavage fluid composition for treating non-small cell lung cancer, and relates to the technical field of cancer treatment. The preparation method of the bronchus lung lavage fluid composition for treating the non-small cell lung cancer comprises the following steps: S1, performing metagenome sequencing on a BALF sample, S2, grouping by R / NR based on differential strains obtained in S1 to obtain core bacteria, performing single-strain Kaplan-Meier survival analysis on the strains, and determining the survival rate of the single-strain Kaplan-Meier to obtain the bronchus lung lavage fluid composition for treating the non-small cell lung cancer. Finally, seven key microorganisms, namely bronchopulmonary lavage fluid combinations, which are remarkably related to immunotherapy PFS are locked; s3, determining the relationship between the seven key BALF bacteria and the existing immune therapeutic effect marker; and S4, verifying the generation conditions of IL6, IL8 and RANTES cytokines promoted by the seven strains through an in-vitro cell experiment, and revealing the activation and enhancement effects of the seven strains on immune cell functions. According to the invention, the immunotherapy effect of the non-small cell lung cancer patient can be promoted to be improved by combining a plurality of beneficial specific microorganisms in an airway administration mode. In conclusion, the method has a good application prospect.

The utility model discloses lung lavage fluid collecting equipment, which relates to the field of medical auxiliary devices, is used for solving the problem that collected lung lavage fluid is polluted due to the fact that a connecting hose falls off when the connecting hose is directly placed at the upper end of an outer tank body, and comprises the outer tank body, an upper cover and the connecting hose, the end part of the connecting hose is positioned in the outer tank body; the connecting hose and the negative pressure bag can be quickly clamped through the connecting structure, the connecting hose is prevented from falling off from the outer tank body, the negative pressure bag is located in the outer tank body, the situation that bacteria enter the outer tank body to pollute lung lavage fluid can be reduced, the top end of the negative pressure bag can abut against the air bag, and the volume of the air bag is reduced; therefore, the air bag filled with air is extruded and then abuts against the matching block to move, the connecting hose can be blocked through the air bag, the situation that lung lavage fluid continues to flow into the negative pressure bag is avoided, and the situation that the lung lavage fluid in the negative pressure bag overflows is avoided.

The present invention belongs to the field of biomedicine technology, and specifically relates to a composition containing pyruvate, a preparation method thereof and an application thereof. The composition comprises the following raw materials in parts by weight: 2-3 parts of pyruvate and 3-5 parts of modified tyrosine, and the structural formula of the modified tyrosine is:. The composition can significantly reduce the number of inflammatory cells in the bronchoalveolar lavage fluid of mice with acute lung injury, as well as the W / D ratio of lung tissue and MPO activity. At the same time, the composition is used in a relatively small amount, which can avoid side effects such as liver damage caused by long-term use of hormone drugs and reduce drug resistance. The preparation method provided by the present invention is simple and feasible, and provides a new synthetic idea for preparing drugs for treating acute lung injury.

The present invention relates to a primer-probe combination for early detection of endometrial cancer, a methylation detection kit, and the use thereof. Provided in the present invention is a methylation gene marker for endometrial cancer detection, which specifically comprises at least one of VSX1, SYT1, ZNF132 and VWC2 genes. Measuring the methylation levels of the genes can remarkably distinguish subjects with endometrial cancer from subjects without cancer. The gene marker of the present invention can well identify subjects with endometrial cancer and subjects without cancer from each of tissue / urine / brush smear / swab / blood / lavage fluid specimens, and can achieve a good detection effect simply by means of a single index and further improve the detection efficiency by means of multi-index combination.

The utility model relates to the technical field of drainage tubes, and discloses a sandwich drainage tube which comprises an outer tube and an inner tube, one end of the inner tube is located on the inner side of the outer tube, the other end of the inner tube penetrates through the side wall of the other end of the outer tube and is fixedly connected with the outer tube, and a plurality of lavage channels are communicated between the end, located in the outer tube, of the inner tube and the outer tube. A plurality of leading-out holes and a plurality of leading-in holes are formed in the outer wall of the end, close to the lavage channels, of the outer tube in a penetrating mode, the leading-in holes are communicated with the lavage channels respectively, and the leading-out holes are located between every two adjacent lavage channels respectively. According to the sandwich drainage tube, the inner cavity of the inner tube is isolated from the inner cavity of the outer tube through the lavage channel, so that liquid for lavage into the body of a patient through the inner tube directly enters the body of the patient through the guide-in hole, the lavage liquid is prevented from being directly guided out by the outer tube, the lavage efficiency is improved, and the lavage treatment burden of the patient is relieved.

The invention belongs to the technical field of virus detection, and particularly relates to a double-channel real-time fluorescent quantitative PCR (Polymerase Chain Reaction) detection primer, a probe, a detection kit, a detection method and application thereof. The detection sensitivity is high, and the lowest detection limit can reach 10 copies / mL; the detection time period is short, nucleic acid detection can be completed within 45 minutes, and the kit is suitable for clinical and bedside rapid detection and diagnosis; the detection specificity is high, and cross amplification with other 80 pathogens is avoided; the detection accuracy is 100%; virus quantitative analysis can be carried out, and the quantitative linear range is good; the detection repeatability is good, and the precision is high; uDG enzyme is added into a detection system, so that pollution can be prevented; a reference gene is also added into the detection system, so that the quality of the whole extraction and amplification process of the sample can be monitored according to the detection result of the reference gene, and the existence of the RNA of the Enduma virus in samples such as whole blood, serum, plasma, cerebrospinal fluid, urine, alveolar lavage fluid, throat swab and excrement can be detected.

The invention belongs to the technical field of biomedicine, and discloses an antibody for evaluating the curative effect of infantile pneumonia asthma and application of the antibody. The heavy chain CDR sequence of the monoclonal antibody (secreted by the hybridoma cell strain 2B5) is SEQ ID NO: 2-4, the light chain CDR sequence of the monoclonal antibody (secreted by the hybridoma cell strain 2B5) is SEQ ID NO: 6-8, the dissociation constant of the monoclonal antibody and an IL-5R antigen reaches 2.435 * 10 <-1 > / L, and the affinity is high. The antibody can accurately evaluate the curative effect of infantile pneumonia and asthma by detecting the lung function, the ratio of eosinophilic granulocytes in bronchoalveolar lavage fluid and lung tissue inflammation, can also significantly improve airway obstruction and inflammation of asthma model mice, has an effect superior to that of dexamethasone, solves the problems that existing curative effect evaluation is lack of specific tools and has large side effects of therapeutic drugs, and has good clinical application prospects. And a new scheme is provided for curative effect evaluation and adjuvant therapy of infantile pneumonia asthma.

The invention discloses application of irisin in treatment of acute lung injury / acute respiratory distress syndrome. The research finds that the plasma irisin level is obviously reduced in ARDS patients, and the survival prognosis of the patients with the lower irisin level is poorer. Neutrophil as the most inflammatory cells is a cause for promoting lung tissue injury. Further analysis finds that the level of irisin is in negative correlation with the number of circulating neutrophils, and irisin incubation can significantly reduce in-vitro survival promoting (apoptosis delay) phenotypes of neutrophils in ARDS mouse alveolar lavage fluid. Iris receptor integrin alphaVbeta5 inhibitor treatment can promote neutrophil infiltration and aggravate an ARDS process. The invention provides a novel therapeutic drug and strategy for the treatment of acute lung injury / acute respiratory distress syndrome.

The invention relates to the technical field of medical lavage equipment, and discloses a lung lavage flushing and sucking machine which comprises an adjustable water inlet pump for providing lavage fluid input power; one end of the water inlet pipe is connected with the adjustable water inlet pump, and the other end of the water inlet pipe is inserted into the lung through a trachea cannula and is provided with a water injection nozzle; one end of the water outlet pipe is close to the lung to collect waste liquid after lavage, and the other end extends to the far end; the wastewater discharge structure is connected with one end, extending to the far end, of the water outlet pipe and used for receiving wastewater after irrigation. The lavage force is improved through the adjustable water inlet pump, efficient lavage of the deep part in the lung is achieved, meanwhile, continuous collection of waste water is achieved through cooperation of the water outlet pipe and the waste water collecting device, and the lavage efficiency in the lung is improved.

The invention provides a spanishneedles herb exosome as well as a preparation method and application thereof in acute lung injury, and belongs to the technical field of biological medicines. According to the preparation method of the spanishneedles herb exosome provided by the invention, the spanishneedles herb exosome can be extracted from a plant source through a simple method. In one embodiment of the invention, a lung injury model constructed by using LPS is used as an experimental animal to verify the therapeutic effect of the spanishneedles herb exosome. Results show that after the spanishneedles herb exosome is used for treatment, mouse lung tissue injury and inflammatory cell exudation can be relieved, and lung injury caused by LPS can be relieved; tNF-alpha and IL-1beta in lung lavage fluid of a mouse are remarkably reduced, and lung inflammation infiltration of the mouse can be relieved. Therefore, the spanishneedles herb exosome has the effect of treating the acute lung injury and can be used for preparing the medicine for treating the acute lung injury.

The utility model provides a bronchoalveolar lavage fluid collecting device, belongs to the technical field of alveolar lavage, and solves the problem that lavage fluid subpackaging is troublesome in the prior art. The device comprises a first collection chamber and a second collection chamber which are communicated in a tank body, the second collection chamber is communicated with an insertion pipe, a subpackaging bottle is placed under the insertion pipe, a bottle cap is arranged at an opening in the upper end of the subpackaging bottle in a threaded and sleeving mode, a guide pipe is communicated with the bottle cap, and a sealing plate is arranged on an opening in the lower end of the guide pipe in an attached mode. One end of the sealing plate is hinged to the guide pipe, a torsion spring is arranged at the hinged position, a support is arranged on the outer side of the tank body, and a driving mechanism is arranged on the support. After the tank body collects a certain amount of lavage fluid, the intubation tube is inserted into the subpackaging bottle through the driving mechanism for subpackaging, after the lavage fluid is injected, the intubation tube is pulled out, and the whole process is operated by a mechanical device instead of manual operation, so that the risk of infection caused by contact with the lavage fluid is reduced, and more manpower is saved.

This invention belongs to the field of biodetection technology and discloses specific PCR primers and identification methods for the subspecies of Mycobacterium abscessus. The differentiation effect of this invention on the three subspecies of Mycobacterium abscessus is equivalent to whole-genome sequencing, while the established detection method does not rely on sequencing, is rapid and low-cost, and has low requirements for equipment and personnel, making it applicable to laboratories at all levels. The amplification method has low template requirements; it is applicable to raw samples such as sputum, bronchoalveolar lavage fluid, pleural and peritoneal fluid, cultures, and extracted nucleic acids, and is not culture-dependent. Identification of the three subspecies is based on product length rather than amplification negative / positive (presence or absence of bands), avoiding false negative results. The product length differences are significant (above 1000 bp), making results easy to interpret, reducing the impact of electrophoresis errors on results, and improving the accuracy and stability of detection. The detection reagents based on this invention can be widely used in clinical precision testing and epidemiological monitoring, among other related fields.

The invention relates to the technical field of biomedicine, in particular to a group of key biomarkers for predicting endometrial receptivity, including specific microbial strains and metabolites, and a prediction model containing the markers. The method comprises the following steps: collecting a uterine cavity lavage fluid sample, carrying out 16S rRNA gene sequencing and non-targeted metabonomics analysis, and screening out eight key microbial strains and eight key metabolites; based on the markers, the following diagnostic models are constructed: a model only based on eight microbial strains; a model based on only eight metabolites; a combined microorganism and metabolite model; and a clinical data model is further combined. According to the method, a microbiome and metabolome multi-omics conjoint analysis strategy is adopted, strict screening is carried out in combination with LASSO regression, SVM-RFE and other machine learning algorithms, and the obtained biomarker is high in specificity. The constructed model, especially a combined model, shows high prediction precision and good calibration degree through verification of various curves.

This invention discloses the application of a peptide SRD in the preparation of drugs for treating acute lung injury, belonging to the field of biomedical technology. In vivo experiments verified the protective effect of peptide SRD on acute lung injury (ALI), particularly its effect on improving AT2 mitochondrial function. In animal models of ALI, tail vein injection of peptide SRD significantly reduced the protein concentration and total cell count in bronchoalveolar lavage fluid, significantly alleviated the severity of lung injury, lowered histological scores, significantly decreased SOD2 acetylation levels while significantly increasing total SOD2 protein levels, and significantly increased SPC levels (an indicator of AT2 survival). ELISA analysis showed a significant decrease in the levels of IL-6, IL-1β, and TNF-α, indicators of pneumonia in mice. These experimental results confirm that the antioxidant peptide SRD can improve oxidative stress damage in ALI, effectively reduce AT2 cell damage under ALI conditions, promote AT2 regeneration and repair, effectively improve lung function, and reduce the inflammatory response of damaged lungs, thus exhibiting a good therapeutic effect on ALI.

The utility model provides a catheter device for subsection bronchial lavage, which comprises an inner catheter for lavage fluid injection and suction and a mesh basket mechanism for plugging and positioning, and the mesh basket mechanism is arranged on the outer side of the front end of the inner catheter; the mesh basket mechanism comprises a mesh basket body located on the inner side and a film sleeve located on the outer side, and the mesh basket body and the film sleeve are arranged in a stacked mode in the radial direction of the inner catheter. The mesh basket body is formed by weaving a plurality of filaments, and the filaments at least comprise shape memory alloy wires. The utility model can realize the positioning and plugging effect at the specified position in the subsection bronchial tube, the mesh basket mechanism automatically opens to achieve the plugging function, and the utility model has the advantages of convenient operation and strong practicability.

The invention provides a combined marker for predicting intrauterine adhesion after abortion curettage, a kit and application, and belongs to the technical field of biological detection. The method comprises the following steps: prospectively collecting macrophages of decidua of a subject, wherein the subject is in Damp; the method comprises the following steps of: selecting a non-IUA group and an IUA group according to B ultrasonic follow-up visit results of two months after operation, and analyzing gene differential expression of macrophages of the two groups of subjects, difference of intrauterine microbiota and change of serum metabolites to finally obtain a method capable of accurately predicting intrauterine adhesion after abortion curettage operation. According to the method, the model efficiency of predicting intrauterine adhesion after abortion curettage is as high as 97.8%, and the method has the advantages of being low in cost and simple and rapid in detection method and has a large application prospect.

The application discloses a kind of nanoparticles for removing lung mucus and its preparation method and application, it is related to the field of biological medicine.The nanoparticles of the application are composed of inner core and shell coated on the surface of the inner core, wherein the inner core contains citric acid and photoluminescent polymer-aliphatic polyester copolymer;The shell contains deoxyribonuclease and hydrophilic polymer.The nanoparticles provided by the application have excellent biocompatibility and multifunctional integration characteristics, which realizes effective penetration of lung mucus barrier, specific degradation of DNA network, down-regulation of pro-inflammatory factors and inhibition of mucus production in sequence through cascade response mechanism, breaking through the limitations of traditional single therapy.In addition, the in vivo experimental results show that it can significantly reduce the thickness of lung mucus and the protein concentration of lavage fluid, and effectively relieve airway obstruction, and can be used for removing lung mucus.

The present application provides a kind of respiratory tract sampler for collecting avian tracheal lavage fluid, belong to the technical field of poultry respiratory tract sampling instrument, including support part, flexible catheter part, positioning and fixing assembly, elastic catheter head assembly, elastic sliding sleeve assembly and inner integrated tube assembly;Support part opens poultry beak, flexible catheter part extends into trachea, insertion cylinder is recycled in head connection pipe, elastic fin supports flexible fin, avoids bending and reduces mucosa irritation;After reaching the predetermined depth, inner integrated tube assembly provides positive pressure gas, drives insertion cylinder to extend, makes limit inclined table and clamping inclined table self-locking, through-hole is exposed in trachea, positive pressure simultaneously provides oxygen for a short time;Subsequently switch to lavage mode, lavage fluid is washed trachea through through-hole, then switch negative pressure back suction to collect sample;After use, move sliding sleeve, manually push and press flexible head to make insertion cylinder reset, it is convenient to disinfect and reuse;Can reduce poultry discomfort, accurately control lavage position, realize oxygen supply, lavage, back suction multi-functional switching.

The present application relates to the technical field of medical apparatus and instruments, in particular to a bronchoscope alveolar lavage fluid collector, which is applied to a bronchoscope alveolar lavage fluid suction system, the suction system comprises a bronchoscope unit, a waste liquid collecting unit and a negative pressure aspirator, and the bronchoscope unit, the collector, the waste liquid collecting unit and the negative pressure aspirator are connected in series, the collector comprises a valve mechanism, an adapter mechanism and a specimen jar; the specimen jar is detachably installed on the adapter mechanism. The valve mechanism is communicated with the bronchoscope unit and the waste liquid collecting unit respectively, and the adapter mechanism and the detachable assembly structure of the specimen jar are matched, when sampling, the specimen jar is only needed to be installed on the side of the valve mechanism by using the adapter mechanism, and a complete sampling channel can be constructed, after sampling, the sampling channel can be switched to a waste liquid collecting channel by only removing the adapter mechanism, and the pipeline between the bronchoscope unit and the waste liquid collecting unit does not need to be repeatedly detached and connected, so that the pipeline pollution risk and the operation complexity are reduced.

The invention provides a dry powder inhalation preparation taking enoxone as an active ingredient. The preparation is small in particle size, high in lung delivery efficiency, small in dosage and capable of remarkably improving the medication compliance of patients. The dry powder inhalation preparation can significantly reduce the level of white blood cells in pulmonary alveolar lavage fluid of a bronchial asthma rat model, improve the lung function and the lesion degree of trachea, bronchus and lung, and has an obvious treatment effect on bronchial asthma.