11 results about "Have Nausea" patented technology

This invention relates to an azabicyclo[3.1.0]hexane derivative that can be used as a 3C-like protease inhibitor. This azabicyclo[3.1.0]hexane derivative can be used to treat fever, nausea, vomiting, headache, dyspnea, fatigue, respiratory tract infection, olfactory and gustatory disturbances and their complications, or combinations thereof, caused by novel coronavirus infection.

This invention provides a method for treating postoperative nausea and vomiting using buccal acupuncture combined with a triple antiemetic regimen. The method employs a combined intervention of buccal acupuncture and a triple antiemetic regimen. The triple regimen consists of a 5-HT3 receptor antagonist, a glucocorticoid, and a dopamine receptor antagonist, administered intravenously in two separate doses. The buccal acupuncture uses CA-2 (upper jiao), CA-3 (middle jiao), and CA-4 (lower jiao) as core acupoints, with auxiliary and reinforcing acupoints added based on the surgical site and high-risk groups. A standardized procedure of pecking stimulation is applied, along with a corresponding postoperative remedial antiemetic medication regimen. This invention organically combines multi-target drug blockade with buccal acupuncture's visceral regulation, synergistically enhancing the antiemetic effect, reducing the incidence of nausea and vomiting, and decreasing the need for remedial medication. The regimen is highly standardized, widely adaptable, and can meet the postoperative nausea and vomiting control needs of various surgeries and high-risk groups. It exhibits good safety, strong repeatability, and high clinical application value.

Methods and compositions comprising carotenoids for the treatment or prevention of nausea, e.g., chemotherapy-induced nausea and vomiting.

This invention belongs to the field of traditional Chinese medicine technology, and relates to a topical Chinese medicine composition, topical drug, topical patch, acupoint patch, and preparation method and application for treating nausea and vomiting caused by chemotherapy for intracranial tumors. The Chinese medicine composition consists of the following raw materials in parts by weight: 1-2 parts of Ligusticum chuanxiong, 1-2 parts of Gastrodia elata, 2-4 parts of Uncaria rhynchophylla, 1-2 parts of Citrus aurantium, 1-2 parts of Sinapis alba, 1-2 parts of Clematis chinensis, 0.5-1 part of Melia toosendan, 0.5-1 part of Panax ginseng, 1-2 parts of Pinellia ternata, 1-2 parts of Albizia julibrissin bark, 0.5-1 part of Lentinus edodes, and 1-2 parts of Astragalus membranaceus. This Chinese medicine composition has the effects of relieving nausea and vomiting, soothing the liver and strengthening the spleen, detoxifying and eliminating turbidity, calming the liver and extinguishing wind, and calming the mind and soothing the nerves. It not only effectively controls the nausea and vomiting symptoms caused by chemotherapy for intracranial tumors, but also harmonizes the body's Qi and organ functions. The Chinese medicine composition has a simple formula, widely available ingredients, and a simple preparation method; it is for topical application, convenient for clinical use, and has low adverse reactions.

The invention discloses anti-vomiting hydrolyzed whey protein and a preparation method thereof, and belongs to the technical field of food processing. The product provided by the invention reduces the digestion burden of protein and relieves the symptom of vomiting. According to the method disclosed by the invention, protein sequences are mutually crosslinked by virtue of a treatment mode of first fibration, second polymerization and final hydrolysis, and a hydrolyzed polypeptide sequence is changed, so that the abundance of the polypeptide SLAMAASDISLA in a hydrolysate is improved. The polypeptide has the characteristics of being easy to recognize by intestinal peptidase and relatively high in PepT1 affinity, the bioavailability of protein is improved, and the deamination proportion of unutilized amino acid is reduced, so that substances generating nitrogen-containing toxoid are reduced, the stimulation of toxin accumulation on gastrointestinal mucosa is relieved, and the symptoms of nausea, vomiting and the like of a user are avoided.

A nasal spray solution for hangovers and method for its preparation. The nasal spray solution may be used to alleviate headache, fatigue, nausea, redness of the eyes, raised blood pressure, congestion, dizziness and other symptoms resulting from the consumption of alcohol. The main active components of the nasal spray solution are vitamin B12, aloe vera extract, L-glutamine, and potassium chloride.

Amisulpride can be used to treat postoperative nausea and / or vomiting in patients who have been given prophylactic medication for postoperative nausea and / or vomiting, and in which the dose of amisulpride is 7.5 to 15 mg.

The disclosure relates to the use of phosphodiesterase 1 (PDE1) inhibitors in combination with a Compound of Formula VIII or a Compound of Formula IX, as described herein, or in combination with an antiemetic agent, such as an antipsychotic agent, e.g., olanzapine, for preventing or treating nausea and / or vomiting, e.g., CINV (chemotherapy-induced nausea and vomiting). In some embodiments, the Compound of Formula VIII or the Compound of Formula IX is used as mono-therapy (i.e., without a PDE1 inhibitor).

Use of sesquiterpenoids having the structures of formula (I) and formula (П) in relieving nausea and vomiting. The sesquiterpenoids having the structures of formula (I) and formula (П) are cedrol and analogs, racemates, stereoisomers, tautomers, isotopically labeled compounds, solvates, polymorphs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof, wherein R 1 to R 8 are as described in the claims and the description. The compounds having the structures of formula (I) and formula (П) can reduce kaolin intake in pica rats, significantly alleviate the symptoms of nausea and vomiting induced by chemotherapeutic drugs such as cisplatin when used in tumor treatment, and can also relieve vomiting caused by gastrointestinal injury, inflammatory diseases, anorexia, etc. In addition, the compounds having the structures of formula (I) and formula (П) can also be used in the preparation of drugs for relieving / treating nausea and vomiting or in the preparation of foods for assisting in protecting the gastric mucosa.

A disposable, self-contained electro-stimulation device configured with paired cutaneous electrodes for placement over specific acupuncture and neurostimulation points (such P6) on a patient's wrist, delivering controlled electrical pulses to reduce or prevent nausea and vomiting following surgery or anesthesia. Its advanced circuitry trades boost-converter efficiency for total system energy conservation, optimized for the low-duty-cycle pulse output used in neuromodulation rather than continuous high-power operation. Its single-IC, digitally controlled pulse engine performs both biphasic stimulation and contact verification, optimizing it for compact, battery-powered wearable medical devices. It also uses a miniature Hall-effect magnetic-field sensor positioned over a planar helical trace that carries the stimulation current, producing a proportional magnetic field detectable by the Hall sensor for the non-invasive current detection and skin-contact verification.

Use of a compound of formula (I) or its stereoisomer, hydrate, metabolite, solvate, pharmaceutically acceptable salt, co-crystal or a composition thereof, in the manufacture of a medicament for preventing postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting.