137 results about "Have Nausea" patented technology

Provided are methods for the treatment of SCLC patients by administering therapeutic amounts of lurbinectedin by intravenous infusion. Also provided are methods of treating cancer by administering lurbinectedin in combination with other anticancer drugs, in particular topoisomerase inhibitors. The invention further relates to the administration of lurbinectedin in combination with anti-emetic agents for effective control of symptoms related to nausea and vomiting, reduced lurbinectedin dosages to achieve a safer administration and an increase in the number of treatment cycles. Stable lyophilized formulations of lurbinectedin are also provided.

The invention belongs to the technical field of health-care food, and particularly relates to a composition and oral drops with the effects of dispelling the effects of alcohol, protecting the liver and relieving hangover as well as a preparation method and application of the composition and the oral drops. The invention provides a composition taking silybin eutectic crystal, curcumin eutectic crystal, ampelopsis grossedentata extract, pyrroloquinoline quinone disodium salt, reduced glutathione, alpha-ketoglutaric acid, vitamin, hericium erinaceus extract, frankincense extract, licorice extract and the like as main active ingredients, and the composition is subjected to scientific formula screening and functional verification, and has the advantages that the composition has the obvious curative effect, and the curative effect is obvious; the traditional Chinese medicine composition can effectively improve the metabolism of ethanol, protect liver and gastric mucosa, and is helpful for relieving hangover-related symptoms such as fatigue, thirst, sleepiness, headache, dry mouth, stomachache, nausea, hypomnesis, inattention and the like.

The invention discloses an anesthesia reviving room risk assessment system for postoperative nausea and vomiting prediction, relates to the technical field of postoperative nausea and vomiting prediction, and aims to perform multi-modal fusion on clinical features of a patient and brain function signals to realize basic probability calculation of postoperative nausea and vomiting risks, and introduce real-time dynamic physiological parameters as regulatory factors to realize postoperative nausea and vomiting risk prediction. And performing adaptive adjustment on the basic prediction result to generate a comprehensive risk probability value. The system can collect and process data in real time after a patient enters an anesthesia reviving room, and dynamic and personalized risk assessment is achieved. Compared with a traditional scoring method which only depends on static clinical features, the method has the advantages that tiny fluctuation of the postoperative physiological state of the patient can be captured, prediction precision and timeliness can be improved, clear decision support can be provided for nursing staff, and therefore preventive intervention measures are optimized, and the occurrence rate of complications is reduced.

The invention relates to the technical field of biological medicines, and provides a pharmaceutical composition for treating liver cancer, which is prepared from the following raw material medicines in parts by weight: 3 to 8 parts of radix paeoniae rubra, 1 to 3 parts of fructus sophorae, 3 to 10 parts of rhizoma polygoni cuspidati, 3 to 20 parts of spica prunellae, 3 to 20 parts of herba hedyotidis diffusae, 3 to 10 parts of herba violae, 2 to 5 parts of turtle shell, 1 to 5 parts of radix angelicae sinensis, 1 to 3 parts of rhizoma curcumae, 1 to 3 parts of apios fortunei maxim and 3 to 5 parts of fructus polygoni orientalis. According to the technical scheme, the problems that in the prior art, after radiotherapy and chemotherapy are conducted on patients, obvious side effects can be generated, such as the symptoms of inappetence, nausea and vomiting, diarrhea, stomachache, dental ulcer and the like, and some patients have the symptoms of listlessness, weakness, shortness of breath, alopecia and the like are solved.

The invention provides the aprepitant and palonosetron hydrochloride compound emulsion for injection, the compound emulsion has better stability, nausea and vomiting can be more conveniently and effectively prevented and treated, and the medication compliance of patients is improved.

The invention provides a traditional Chinese medicine composition for relieving chemotherapy side effects, traditional Chinese medicine compound essential oil and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1-9 parts of pericarpium citri reticulatae, 1-9 parts of pericarpium citri reticulatae viride, 1-9 parts of clove, 1-9 parts of fennel, 1-9 parts of ginger, 1-9 parts of pogostemon cablin and 1-9 parts of rhizoma atractylodis. The traditional Chinese medicine composition is mainly used for treating abdominal distension pain, nausea and vomiting caused by damp turbidity resistance and spleen and stomach disharmony through the effects of promoting qi circulation, removing dampness, strengthening the spleen and harmonizing the stomach. Experimental results show that the traditional Chinese medicine compound essential oil prepared from the traditional Chinese medicine composition can reduce allotriophagia behaviors of rats and improve ingestion and drinking habits, has a recovery effect on metabolite disorder caused by chemotherapy-related nausea and vomiting, and provides a theoretical basis for a supplementary treatment method of chemotherapy-related nausea and vomiting.

The invention relates to the technical field of intelligent nursing, in particular to an intelligent nursing intervention system and method for nausea and vomiting after a pulmonary operation. The analysis of nausea and vomiting performance is established on the basis of continuous and quantifiable indexes, the sensitivity of judging a risk trend is improved, a risk change path is identified through a long-short-term memory neural network, an influence rule of intervention intensity on a nausea and vomiting evolution trend is accurately described, stage prediction of a nursing intervention effect is realized, and the risk prediction accuracy is improved. Structural optimization is performed on an intervention time sequence and nursing task allocation and execution rhythm through a convolutional neural network, an intervention rhythm path is recombined in combination with resource adaptation information, the coverage density of intervention measures for risk periods is enhanced, integrated response of nursing resources in a high-sensitivity interval is promoted, and synchronous optimization of task allocation and time sequence matching is realized.

The aluminum alloy door and window production frame paint spraying device comprises a fixing frame, a paint spraying device body and supporting legs, the paint spraying device body is fixedly connected to the top of the right side of the fixing frame, and the supporting legs are fixedly connected to the four corners of the bottom of the fixing frame. By arranging the controller, the controller starts the extraction mechanism, the extraction mechanism extracts harmful gas, then the harmful gas is filtered through the filtering mechanism, a user is prevented from inhaling a large amount of harmful gas, and then the effect of sucking and filtering the harmful gas is achieved; the problems that volatile organic compounds and other harmful gases are released in the paint spraying process, a structure for sucking and filtering the harmful gases is not provided, and a large amount of gases are sucked to damage body health and even cause serious diseases to stimulate a respiratory system, cause dizziness, nausea and other uncomfortable symptoms, and the like are solved. And certain potential safety hazards exist.

Compositions comprising cannabidiol and one or more compounds that are inhibitors of CYP2C19 and CYP3A4 enzymes are disclosed. Methods of using such compositions to treat pain, epilepsy, sleep deprivation, vomiting, nausea, psychosis, anxiety, depression, movement disorders, and other neuropsychiatric or neurogenic diseases are also provided. Compositions comprising cobicistat or a pharmaceutically acceptable isomer, salt, and / or solvate thereof; and at least one therapeutic agent metabolized by CYP2C19 and optionally CYP3A4 are provided. A method for inhibiting CYP2C19 and optionally CYP3A4 in a patient in need thereof is also provided, comprising administering to the patient an amount of cobicistat or a pharmaceutically acceptable isomer, salt, and / or solvate thereof effective to inhibit CYP2C19 and optionally CYP3A4 in the patient.

Provided are methods for the treatment of SCLC patients by administering therapeutic amounts of lurbinectedin by intravenous infusion. Also provided are methods of treating cancer by administering lurbinectedin in combination with other anticancer drugs, in particular topoisomerase inhibitors. The invention further relates to the administration of lurbinectedin in combination with anti-emetic agents for effective control of symptoms related to nausea and vomiting, reduced lurbinectedin dosages to achieve a safer administration and an increase in the number of treatment cycles. Stable lyophilized formulations of lurbinectedin are also provided.

The invention discloses a position pad for preventing supine hypotension syndrome in cesarean section. The position pad comprises a waist assembly, a head assembly, a leg assembly and a supporting assembly. The front end of the supporting assembly is provided with the head assembly, the middle is provided with the waist assembly, and the rear end is provided with the leg assembly. The head assembly comprises a headrest, a lifting ring, a cross rod, an inclined ring, an inclined bottom plate, an inclined sliding groove, a lifting assembly, an inclined assembly, a limiting seat and an adjusting plate. An adjusting plate is arranged in the middle of the front end of the supporting assembly. A limiting seat is arranged in the middle of the adjusting plate and movably connected with the lifting assembly; an inclined bottom plate is arranged at the bottom of the headrest; the front end of the inclined bottom plate is provided with an inclined sliding groove which is in sliding connection with the lifting assembly, and the rear end of the inclined bottom plate is provided with a cross rod; lifting rings are symmetrically arranged at two ends of the cross rod and rotationally connected with inclined assemblies; the lifting assembly and the inclining assembly of the head assembly can adjust the position of the head, and discomfort symptoms such as dizziness, nausea and vomiting of the puerpera can be effectively relieved.

Nausea and vomiting are unpleasant events caused by a variety of triggering factors. Wherein medicines often cause nausea and vomiting. An anti-tumor chemotherapeutic agent is one of the most emetic drugs, and often causes chemotherapy-induced nausea and vomiting (CINV). The latter seriously impairs the therapeutic effect and the quality of life of the patient. It is of great interest in determining agents capable of preventing and combating drug-induced nausea and vomiting, including CINV. A calcitonin gene-related peptide (CGRP) is a neuropeptide having various effects in a human body. However, neuropeptide effects in the brain are still to be clarified. CGRP receptor antagonists (named as gezepam) have been recently approved for use in the treatment of migraine. The use of gezepams for the direct treatment of nausea and vomiting, including CINV, is described.

Amisulpride is used in the therapy of nausea, vomiting or retches. The therapy may utilize a novel injectable formulation, in unit dosage form, comprising less than 50 mg amisulpride.

Provided are methods for the treatment of SCLC patients by administering therapeutic amounts of lurbinectedin by intravenous infusion. Also provided are methods of treating cancer by administering lurbinectedin in combination with other anticancer drugs, in particular topoisomerase inhibitors. The invention further relates to the administration of lurbinectedin in combination with anti-emetic agents for effective control of symptoms related to nausea and vomiting, reduced lurbinectedin dosages to achieve a safer administration and an increase in the number of treatment cycles. Stable lyophilized formulations of lurbinectedin are also provided.

A Limosilactobacillus fermentum strain capable of alleviating a hangover and the use thereof. The strain is at least one strain of Limosilactobacillus fermentum ibiome020, Limosilactobacillus fermentum ibiome021 and Limosilactobacillus fermentum ibiome022 respectively deposited with deposit numbers of CCTCC NO: M 2024188, CCTCC NO: M 2024222 and CCTCC NO: M 2024189. The Limosilactobacillus fermentum is a natural bacterium derived from the intestine of a healthy human and has high safety; can alleviate chronic / acute alcoholism, alcoholic intestinal damage or alcoholic liver damage; can accelerate the metabolism of ethanol and / or acetaldehyde, and delay the onset of intoxication; can shorten the sobering-up time; can reduce the mortality caused by drinking alcohol; can reduce the liver index; can lower the level of AST and / or ALT in serum; can alleviate discomfort caused by ethanol and / or acetaldehyde, and mitigate symptoms such as dizziness, headache, nausea and vomiting, and hangover after drinking alcohol; can ameliorate oxidative stress caused by alcohol, and increase the level of GSH in the liver; and also has excellent resistance to gastrointestinal fluid and bile salt, and can adapt to the complex environment within the body.

The invention belongs to the technical field of biological medicines and microorganisms, and particularly relates to a parabacteroides couchneri MRD02 and application thereof, the parabacteroides couchneri is Parabacteroides couchneri MRD02, the preservation number is GDMCC No.64793, and the preservation unit is Guangdong Province Microbial Culture Collection Center. The invention further discloses a preparation method of the parabacteroides couchneri MRD02 and application of the parabacteroides couchneri MRD02. The Parabacteroides goldsteinii MRD02 disclosed by the invention can be used for remarkably inhibiting joint swelling and systemic inflammation of rheumatoid arthritis of mice, and the inhibiting effect of the Parabacteroides goldsteinii MRD02 is remarkably superior to that of other parabacteroides strains; meanwhile, due to the fact that the usage amount of the Parabacteroides goldsteinii MRD02 is small, gastrointestinal reactions of nausea, vomiting or diarrhea are not found in the Parabacteroides goldsteinii MRD02, and anaphylactic reactions are also not found in the Parabacteroides goldsteinii MRD02.

The present invention relates to the field of medicine and food technology, and relates to a composition for relieving nausea and vomiting, and specifically to a composition obtained by mixing, heating and beating with ginseng and ginger as main raw materials, and its application in the preparation of a drug for relieving / treating nausea and vomiting. In the composition, the mass ratio of ginseng to ginger is 1:10-1:60, and the mass ratio of the mixed raw materials of ginseng and ginger to water is 1:10-1:40. The composition comprises total ginsenosides and total gingerols, wherein the total ginsenoside content is 15-55%, the total gingerol content is 2.5-9%, and the rare ginsenoside content accounts for more than 60% of the total ginsenoside content of total ginseng. The composition is prepared by the following method: mixing ginseng with fresh ginger, soaking in water, mixing and beating at 60-100°C for 30-75min, that is. The composition of the present invention can significantly relieve nausea and vomiting, and can be used to treat nausea and vomiting caused by various reasons.

The invention relates to the technical field of ginger moxibustion, in particular to a portable temperature-controllable ginger moxibustion device for arresting vomiting of tumor patients, which comprises a shell, a tube is fixedly connected to the inner side wall of the shell, a pore plate is fixedly connected to the bottom of the tube, a temperature sensor is mounted on the inner side wall of the tube, and a cover is in threaded connection to the top of the shell. A cylinder is fixedly connected to the bottom of the cover body, and an electric heating rod is mounted at the bottom of the cylinder; the electric heating rod is used for simulating heating power of moxa in traditional ginger-separated moxibustion, controllable heating power is used for exciting drug efficacy of ginger of ginger slices on the pore plate, the synergistic effect mechanism that ginger penetrates through heating power and drug efficacy enters the acupoint is perfectly rescribed, the device is designed according to the core requirement of descending adverse-rising energy and arresting vomiting of tumor patients, the device can accurately act on related acupoints for arresting vomiting, and the effect is achieved. The symptoms of nausea and vomiting caused by chemoradiotherapy and the like are effectively relieved.

The present disclosure relates generally to methods of treating, preventing, or reducing nausea, vomiting, or a combination thereof, hyperemesis gravidarum (HG), nausea and vomiting of pregnancy (NVP), or sequelae thereof in a human subject in need thereof, the method comprising administering to the human subject a therapeutically effective amount of an antibody that specifically binds to human glial cell line-derived neurotrophic factor family receptor alpha-like (GFRAL).

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating postoperative digestive tract reaction of malignant tumors, a preparation and application. The traditional Chinese medicine composition comprises the following active ingredient raw materials in parts by weight: 10-20 parts of fried codonopsis pilosula, 10-20 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 1-10 parts of liquorice, 10-20 parts of fried endothelium corneum gigeriae galli, 15-25 parts of fried malt, 25-35 parts of adina rubella hance root, 25-35 parts of wild grape root, 15-25 parts of Chinese actinidia root and 15-25 parts of coix seed. The traditional Chinese medicine composition and the preparation can effectively treat patients with malignant tumor postoperative digestive tract reaction, effectively improve symptoms of abdominal distension, stomachache, nausea, vomiting, diarrhea, constipation, anorexia, sour regurgitation, oral cavity / throat dryness and the like of the patients, improve the life quality of the patients and have good safety.

The GIP receptor agonists of this disclosure have antiemetic properties and can therefore be used to reduce or inhibit the frequency or severity of episodes of nausea or vomiting in patients in need.

The utility model discloses a tumor patient nausea and vomiting evaluation device, and particularly relates to the technical field of tumor patient nausea and vomiting evaluation, the tumor patient nausea and vomiting evaluation, the tumor patient nausea and vomiting evaluation device comprises a digital scoring ruler and a facial expression scoring ruler, the bottom end of the digital scoring ruler is provided with a cavity adapted to the sliding placement of the facial expression scoring ruler, and the side end of the facial expression scoring ruler is provided with an accommodating groove; and rolling wheels are rotationally mounted in the accommodating grooves and are in rolling fit with the side walls of the cavities. According to the device, the facial expression scoring ruler is arranged in the digital scoring ruler in a sleeving manner, so that the device is convenient for medical staff to carry and also convenient for the medical staff to select an evaluation tool which is most suitable for a patient to use.

The invention discloses a traditional Chinese medicine composition for treating nausea and / or vomiting, which is prepared from the following traditional Chinese medicines in parts by weight: 8-10 parts of radix paeoniae alba, 2-6 parts of rheum officinale, 2-6 parts of lindera aggregata and 2-4 parts of liquorice. The traditional Chinese medicine composition is reasonable in formula and clear in monarch, minister, assistant and guide, has the effects of strengthening the spleen, harmonizing the stomach, calming the adverse-rising energy and arresting vomiting, and is suitable for various symptoms of nausea and / or vomiting. Clinical research proves that the traditional Chinese medicine composition can remarkably improve the cure rate and shorten the cure time, is high in total effective rate and good in safety, and has good clinical significance.

Compositions and methods for the control and treatment of obesity, metabolic disorders, nausea and vomiting using ODN peptides and synthetic derivatives thereof are disclosed.

The present invention relates to an oily composition comprising maropitant and an oily carrier. The invention also relates to the use of such a composition in the treatment and prevention of nausea and vomiting in a non-human mammal, in particular a dog or cat.

The utility model discloses a record board for nausea and vomiting conditions caused by chemotherapy, and relates to the field of medical instruments. The recording board comprises a panel and a marking block, wherein the panel is provided with two condition information areas and two condition recording grooves; the condition information area comprises four condition grading areas; four condition grading areas of one condition information area respectively have nausea grade information, and four condition grading areas of the other condition information area respectively have vomiting grade information; the condition recording grooves and the condition information areas are arranged in a one-to-one correspondence mode, each condition recording groove comprises a lower transverse groove, a communicating vertical groove, four communicating transverse grooves and four recording vertical grooves, the recording vertical grooves and the condition grading areas are arranged in a one-to-one correspondence mode and are close to the condition grading areas, and the communicating vertical grooves are located on the outer sides of the recording vertical grooves; the communicating transverse groove communicates with the upper end of the recording vertical groove and the communicating vertical groove, and the lower transverse groove is located at the lower end of the communicating vertical groove and forms a T-shaped groove together with the communicating vertical groove; and seven marking blocks are placed in each condition recording groove.

This invention relates to an azabicyclo[3.1.0]hexane derivative that can be used as a 3C-like protease inhibitor. This azabicyclo[3.1.0]hexane derivative can be used to treat fever, nausea, vomiting, headache, dyspnea, fatigue, respiratory tract infection, olfactory and gustatory disturbances and their complications, or combinations thereof, caused by novel coronavirus infection.

A use of a compound of formula (I) or a stereoisomer, hydrate, metabolite, solvate, pharmaceutically acceptable salt and eutectic thereof or a composition thereof in the preparation of a drug for preventing postoperation nausea and vomiting or chemotherapy-induced nausea and vomiting.

The present invention belongs to the field of biotechnology, and specifically relates to a strain of animal Bifidobacterium lactis subsp. lactis BX‑186 that alleviates the adverse effects of semaglutide. The classification name of the animal Bifidobacterium lactis subsp. lactis provided by the present invention is: Bifidobacterium animalis subsp. lactis, the deposit unit is: General Microbiology Center of China Microbiological Culture Collection Administration Committee, the deposit number is: CGMCC No. 27837, and the deposit time is July 7, 2023. The animal Bifidobacterium lactis subsp. BX‑186 provided by the present invention directly interacts with the intestinal flora, thereby affecting the metabolic activities and physiological functions of the intestinal microorganisms, restoring the balance of the intestinal flora, and can alleviate the gastrointestinal discomfort symptoms caused by semaglutide, including nausea, vomiting and diarrhea, etc., and can also reduce body weight and the content of glycosylated hemoglobin HbA1c in the blood, and has broad application prospects.