11 results about "Alcoholic liver damage" patented technology

This invention discloses a compound peptide nutrient with fat-reducing effects, belonging to the field of health food technology. Specifically, it relates to a VQPIPY peptide or a product containing VQPIPY peptide in the preparation of lipid-lowering drugs or health products, or in the preparation of drugs for treating and / or alleviating alcoholic liver damage. This invention also provides a meal replacement powder containing VQPIPY peptide, shown as a compound of whey powder, milk powder, oats, spinach powder, allulose, and camel milk peptide in a specific ratio. Through the synergistic effect of its components, this product achieves multiple effects such as providing satiety, inhibiting blood sugar, and lowering blood lipids. It is characterized by balanced nutrition, safety, effectiveness, and good taste, and can be used for weight management and daily health maintenance.

This invention relates to a composition for improving alcoholic liver damage, belonging to the field of health product technology. This application provides the use of rhodioloside and lactose-N-trisaccharide in the prevention and / or inhibition of alcoholic liver disease. This application also provides a composition of human lactose oligosaccharides and rhodioloside. The compositions described in this application can prevent the occurrence of alcoholic liver disease or inhibit its further deterioration. This application provides a green, safe, and healthy composition, offering an ideal composition for protecting human health.

This invention discloses the application of American ginseng glycoprotein extract in the preparation of drugs for treating alcoholic liver disease, belonging to the field of biomedical technology. This invention verifies that TD can significantly reduce serum ALT, AST, and TG levels in ALD mice, effectively reducing liver damage and lipid accumulation; inhibit NLRP3 protein expression and its downstream targets, effectively alleviating liver inflammation and pyroptosis; and improve intestinal flora imbalance in ALD mice. American ginseng glycoprotein extract has multi-target protective effects against alcoholic liver disease, reducing alcohol-induced liver tissue inflammation and oxidative stress damage. It has a mild composition and high safety profile, and can synergistically exert effects in liver protection, anti-inflammation, and antioxidation, making it suitable for adjunctive intervention and long-term management of alcoholic liver disease, providing a natural, mild, and effective protective pathway for alcoholic liver damage.

The invention relates to a novel application of ergothioneine, in particular to an application of ergothioneine in preparation of a product for preventing or improving alcoholic liver injury. The invention finds that the ergothioneine has a very remarkable effect in the aspect of preventing or improving the alcoholic liver injury, and the ergothioneine particularly has the effects of preventing or relieving liver pathological injury, regulating alcohol metabolism, regulating lipid metabolism, improving liver oxidative stress injury and improving the liver inflammation state. The ergothioneine is used for preparing products with related effects and has an application prospect.

The application provides application of Gao Yao-4 medicine powder in preparation of a medicine for treating or preventing acute alcoholic liver, and belongs to the field of medicine. It is found for the first time that the drugs in the Gao Yao-4 medicine powder have a combined effect, can effectively reduce the content of AST, ALT and TBIL in serum and liver tissue after a large amount of drinking, effectively reduce the content of TC, TG, MDA, TNF-alpha, IL-1beta and IL-6 in liver tissue after a large amount of drinking, improve the content of SOD, reduce the apoptosis rate of liver tissue cells, improve the expression amount of Bc1-2 protein, and reduce the expression amount of Bax, caspase3 and C-caspase3 protein, and has a repairing and protecting effect on alcoholic liver cell damage. It is shown that the Gao Yao-4 medicine powder can be used for treating / preventing acute alcoholic liver damage, and does not have side effects, and has high safety.

The invention provides application of setuzumab in preparation of a medicine for treating non-alcoholic liver injury, and belongs to the technical field of biological medicine. Results show that the setutuzumab can significantly reduce ALT level and AST level in serum of a mouse with non-alcoholic liver injury, so that the setutuzumab can effectively prevent and / or treat the non-alcoholic liver injury. Space exploration experiment results show that the exploration distance of the quadrant where the platform of the non-alcoholic liver injury model mouse treated by the cetuzumab is located, the exploration time of the quadrant where the platform is located and the crossing frequency are obviously larger than those of a control group, so that the cetuzumab effectively improves the spatial memory ability and the positioning cruising ability of the non-alcoholic liver injury model mouse; therefore, the effect of treating the cognitive impairment caused by the non-alcoholic liver injury is achieved. Open field and tail suspension experiment results show that the cetuzumab can improve depression and anxiety behaviors of non-alcoholic liver injury model mice, and has the effect of treating depression caused by non-alcoholic liver injury.

The invention provides a traditional Chinese medicine health-care product for assisting in preventing alcoholic liver injury, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5 parts of dandelion, 4 parts of radix puerariae, 2 parts of radix paeoniae rubra, 2 parts of honeysuckle, 2 parts of chrysanthemum, 3 parts of poria cocos, 3 parts of coix seeds, 3 parts of fingered citron, 2 parts of pericarpium citri reticulatae, 2 parts of pericarpium citri reticulatae viride, 3 parts of rhizoma atractylodis macrocephalae, 2 parts of hawthorn, 3 parts of liquorice, 3 parts of fructus perillae, 3 parts of salvia miltiorrhiza, 2 parts of radix paeoniae alba, 2 parts of angelica sinensis, 2 parts of rehmannia, 2 parts of fructus lycii, 3 parts of astragalus membranaceus and 4 parts of hovenia dulcis thunb. The traditional Chinese medicine composition has the effects of clearing heat, resolving dampness, soothing the liver, regulating qi, strengthening the spleen and the stomach, reducing phlegm, promoting blood circulation to remove blood stasis, nourishing yin, tonifying qi, relieving alcoholism, preventing alcoholic liver injury in an auxiliary manner and promoting the body to recover a normal and healthy state.

This invention discloses the application of a traditional Chinese medicine composition in the preparation of drugs, foods, or health products for the prevention and / or treatment of Alzheimer's disease and / or neuroinflammation and / or cognitive impairment. The traditional Chinese medicine composition includes Hovenia dulcis, mung bean, sea buckthorn or fresh sea buckthorn, tangerine peel, mulberry or fresh mulberry, turmeric, and hawthorn. It exhibits good preventive and therapeutic effects on Alzheimer's disease, improves neuroinflammation, and alleviates cognitive impairment. It can effectively avoid the toxic effects of acetaldehyde on the human body, achieve the prevention of drunkenness and rapid sobering up. It has good improvement effects on alcoholic liver damage, alcoholic gastric damage, alcoholic kidney damage, alcoholic brain damage, alcoholic cardiomyopathy, and alcohol-induced cognitive impairment. It also has the effects of protecting the cardiovascular and cerebrovascular systems, strengthening the spleen and stomach, and protecting the liver. It has the advantages of having a small number of medicinal ingredients, low cost, convenient administration, no obvious toxic side effects, and convenient daily carrying. It is suitable for timely administration by people who want to sober up and for preventive health care by the general population. Its market prospects are even broader.

The application belongs to the technical field of proteins, and relates to an anti-digestion peptide capable of relieving alcoholic liver injury, a preparation method and application of the anti-digestion peptide, and the amino acid sequence of the anti-digestion peptide is PIPFPR. The anti-digestion peptide can resist the degradation of gastrointestinal digestive enzymes and be absorbed by intestinal epithelial cells, can resist the decrease of cell viability, eliminate free radicals, resist ethanol-induced oxidative stress, and relieve liver cell injury. The application further provides a preparation method and application of the anti-digestion peptide capable of relieving alcoholic liver injury.