The application provides application of Gao Yao-4
medicine powder in preparation of a
medicine for treating or preventing acute alcoholic liver, and belongs to the field of
medicine. It is found for the first time that the drugs in the Gao Yao-4 medicine
powder have a combined effect, can effectively reduce the content of AST, ALT and TBIL in serum and
liver tissue after a large amount of drinking, effectively reduce the content of TC, TG, MDA, TNF-alpha, IL-1beta and IL-6 in
liver tissue after a large amount of drinking, improve the content of SOD, reduce the
apoptosis rate of
liver tissue cells, improve the expression amount of Bc1-2
protein, and reduce the expression amount of Bax,
caspase3 and C-
caspase3
protein, and has a repairing and protecting effect on alcoholic
liver cell damage. It is shown that the Gao Yao-4 medicine
powder can be used for treating / preventing acute
alcoholic liver damage, and does not have side effects, and has high safety.