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25 results about "Intoxication alcohol" patented technology

Genetically engineered probiotic composition for expressing ADH and ALDH and application thereof in hangover alleviating and liver protection

The invention discloses a genetically engineered probiotic composition for expressing ADH (adenosine dihydrogenase) and ALDH (aldehyde dehydrogenase) and application of the genetically engineered probiotic composition in hangover alleviating and liver protection. The genetically engineered probiotic composition (such as EcN.1917-ADH and EcN.1917-ALDH) is constructed by introducing genes of alcohol dehydrogenase (ADH, NCBI (National Center for Biotechnology Information) Gene ID: 855349) and acetaldehyde dehydrogenase (ALDH, NCBI Gene ID: 855206) of saccharomyces cerevisiae into probiotics (such as escherichia coli). The engineering bacterium shows remarkable ethanol, acetaldehyde and endurance capacity in an in-vitro experiment, and the ethanol degradation rate is remarkably higher than that of a wild type strain; a mouse drunkenness model verifies that drunkenness and death caused by drinking can be reduced through pretreatment, drunkenness tolerance time is remarkably prolonged, and movement coordination disorder caused by alcohol can be improved. The strain can effectively promote alcohol metabolism and relieve alcoholic liver injury, and a new candidate strain is provided for development of a hangover-alleviating and liver-protecting viable bacterial preparation.
Owner:CHONGQING MEDICAL UNIVERSITY

Composition for dispelling effects of alcohol and protecting liver as well as preparation method and application of composition

The invention belongs to the technical field of functional compositions, and discloses a composition for dispelling effects of alcohol and protecting liver as well as a preparation method and application thereof, and the composition comprises the following raw materials in percentage by mass: 13-28% of ginseng, 18-28% of globe artichoke, 10-27% of pueraria peptide, 7-12% of houttuynia cordata, 7-9% of mulberry, 6-9% of gardenia and 10-29% of collagen composite peptide. The composition can reduce alcohol irritation, relieve alcohol absorption and increase the alcohol content; meanwhile, the liver and stomach are protected; meanwhile, alcohol metabolism is rapid, hangover is prevented, headache, dizziness, nausea and other uncomfortable symptoms caused by alcohol are relieved, and the drunkenness degree is relieved. After the medicine is taken for 2-6 months, mild fatty liver and moderate fatty liver can be obviously improved, and severe fatty liver and alcoholic liver can be obviously improved; indexes related to endocrine metabolism, such as blood sugar, blood fat, uric acid, triglyceride, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, glutamic oxalacetic transaminase and glutamic-pyruvic transaminase, are obviously improved.
Owner:GUANGDONG ZHONGTAIYI TRADITIONAL CHINESE MEDICINE TECHNOLOGY CO LTD

System for preventing drunk driving and control method thereof

Disclosed is a drunk driving prevention system and a method of controlling the same, the system including a sensor module that measures alcohol content in exhaled breath of a driver during a breath inspection of the driver, and a control module configured to check a drunken state of the driver according to the alcohol content measured by the sensor module to determine whether the breath inspection is completed and to prevent an engine start when the breath inspection is failed, wherein the control module includes an inspection unit that displays breath inspection guide information through a display unit, and the inspection unit displays the breath inspection guide information based on an engine operation input of the driver.
Owner:HYUNDAI MOBIS CO LTD

Traditional Chinese medicine composition for preventing and treating drunkenness

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for improving alcohol tolerance of a user and relieving uncomfortable symptoms of the user after drinking. Compared with modern medical treatment, the traditional Chinese medicine compound is started from multiple mechanisms of relieving alcoholism, protecting liver and stomach and dredging collaterals and blood stasis, whole-course intervention from acute symptom control to organ injury repair is achieved, and the traditional Chinese medicine compound is more suitable for the complex pathogenesis of alcoholism multi-system injury. According to the formula, an effective traditional Chinese medicine scheme is provided for drunkenness patients according to the core treatment principle of separately eliminating and draining, and clearing away heat and toxic materials. The composition can significantly improve the alcohol tolerance of a user, alleviate the vomiting symptom of the user after drinking, and improve the discomfort symptom of the user after sobering up. The traditional Chinese medicine composition is a pure traditional Chinese medicine formula, is safe and has no toxic or side effect.
Owner:SHANGHAI FOURTH PEOPLES HOSPITAL

Karaoke apparatus

To provide a karaoke device capable of assisting a user to perform karaoke singing well.SOLUTION: In the karaoke device, a karaoke body 10 includes an acquisition part for acquiring an alcohol concentration of exhalation of a user, a scoring processing part for evaluating karaoke singing performed by the user and obtaining a score value, and a first storage processing part for storing user identification information of the user, musical piece identification information of a musical piece, the score value of the karaoke singing, and the alcohol concentration acquired during the karaoke singing in association with one another. And a control unit including a second storage processing unit that stores a music piece as a sober-time high score music piece in a case where a score value of a drinking state is lower than a score value of a sober state, and a presentation unit that presents a message recommending drinking in a case where a music piece selected by a user is a drinking-time high score music piece and presents a message suppressing drinking in a case where the music piece selected by the user is the sober-time high score music piece.SELECTED DRAWING: Figure 2
Owner:DAIICHI KOSHO COMPANY

Method for detecting higher alcohols in serum and application thereof

PendingCN121385149AComponent separationTriple quadrupole mass spectrometryMetabolic kinetics
The invention belongs to the technical field of chemical analysis and detection, and particularly relates to a method for detecting higher alcohols in serum and application of the method in metabolic kinetic analysis of alcoholic beverages. In order to realize the effective separation and synchronous detection of fatty alcohol, aromatic alcohol and isomers thereof, reduce the volatile loss of higher alcohol and the use amount of a sample and reduce the serum matrix effect, the method comprises the following steps: performing pretreatment extraction and derivatization on drunk serum; high performance liquid chromatography-triple quadrupole mass spectrometry is adopted to detect higher alcohols in serum after drinking and the content of the higher alcohols. Results prove that the detection method disclosed by the invention has the advantages of low sample amount, high precision and accuracy, low matrix effect and low detection limit. The detection method disclosed by the invention is used for detecting the content of ethanol and higher alcohol in serum in the metabolic kinetics analysis of the alcoholic beverage, so that the alcoholic beverage with excellent metabolic efficiency can be screened, and data support can be provided for the evaluation of slow drunkenness, fast sobering and light hangover.
Owner:LUZHOU LAOJIAO CO LTD +1

A method for constructing a drunken animal model and application thereof in drunkenness evaluation

PendingCN122623629ABiotechnologyPhysiology
The application discloses a drunk animal model construction method and application thereof in drunk evaluation, and belongs to the technical field of model construction. The technical problems to be solved are that a traditional Kunming mouse drunk model is genetically hybrid, modeling is uneven, data repeatability is poor, drug efficacy verification is inaccurate, and there is no systematic drunk evaluation system. The technical solution points comprise providing a drunk animal model construction method for light and severe drunk animals and a light and severe drunk evaluation method. The drunk animal model construction method based on ICR mice is provided, the drunk model is reproducible, the evaluation indexes are quantifiable, and the drug screening is accurate, and the light and severe drunk evaluation method is provided.
Owner:NINGBO HAIERSHI NEW DRUG TECHNOLOGY CO LTD

A hall sensor-based electric bicycle helmet alcohol detection system

The application discloses a kind of electric bicycle helmet alcohol detection systems based on hall sensor, to improve the safety of driver.The system includes helmet alcohol detection system and car speed control system, both are linked through wireless communication.Helmet alcohol detection system is built-in alcohol detection sensor module, human existence detection module and helmet interface detection module, for judging whether driver drinks and whether helmet is correctly worn.Car speed control system detects the voltage output by hall sensor in vehicle handlebar to judge vehicle driving state;when voltage is non-zero (vehicle driving), the system automatically queries the state of helmet alcohol detection system.If driver drinks or does not correctly wear helmet is detected, the system will make the vehicle unable to drive through car speed control system, and trigger sound and light alarm to remind driver.The application combines wireless communication and sensor technology, can effectively prevent drunk driving and not wearing helmet and other dangerous behaviors, significantly improve the safety of driver.
Owner:HUAIYIN TEACHERS COLLEGE

Application of common turnip polysaccharide in preparation of products for preventing alcoholic liver injury and assisting in dispelling effects of alcohol

PendingCN122056913AOrganic active ingredientsDigestive systemCommon turnipIntoxication alcohol
The invention discloses application of common turnip polysaccharide in preparation of a product for preventing alcoholic liver injury and assisting in dispelling the effects of alcohol, and belongs to the technical field of natural product development and biological medicine. The common turnip polysaccharide prepared through ultrasonic and alcohol extraction is rich in galactose and rhamnose, has high galacturonic acid content, shows typical RG-I type pectic polysaccharide characteristics, can be kept stable in simulated gastrointestinal fluid and directly reaches the colon to play a role; meanwhile, the prepared common turnip polysaccharide can remarkably reduce transaminase increase and lipid accumulation caused by alcohol, and by specifically proliferating beneficial bacteria such as Akkermansia and the like, the intestinal barrier is repaired, and endotoxin is prevented from entering blood; meanwhile, liver hangover alleviating enzymes can be obviously activated, and the drunkenness time is shortened.
Owner:JIANGNAN UNIV +1

Coffee cherry pulp skin fermentation composition-containing drunkenness / fermentation / alcohol feeling enhancing agent

To provide a flavor improvement agent for enhancing the drunkenness feeling and the fermentation or alcohol feeling of a food / drink.SOLUTION: Provided is a flavor improvement agent, which is a flavor improvement agent for enhancing the drunkenness feeling and the fermentation or alcohol feeling of a food / drink, containing a coffee cherry pulp skin fermentation composition, and in which the coffee cherry pulp skin fermentation composition is one produced by a production method comprising lactic acid bacteria fermentation treatment and yeast fermentation treatment of coffee cherry pulp, skin and / or mucilage.SELECTED DRAWING: None
Owner:KIRIN HOLDINGS KK

A traditional Chinese medicine composition with hangover-relieving effects

ActiveCN118286363BNervous disorderAntinoxious agentsIntoxication alcoholTraditional medicine
This invention discloses a traditional Chinese medicine composition for relieving hangovers, prepared from the following raw materials in the indicated weight ratios: 2-5 parts germinated barley, 2-5 parts malt, 2-5 parts Japanese raisin tree fruit, 1-3 parts wild kudzu root, 1-3 parts clove, and 1-3 parts dried plum. This composition primarily targets the symptoms of abdominal distension, nausea, and fluid depletion after drinking alcohol. It utilizes common medicinal and edible herbs to regulate qi, strengthen the spleen, relieve nausea and vomiting, promote fluid production, and astringe sweat. It can significantly shorten the sobering-up time, alleviate the discomfort caused by drunkenness, and reduce the damage of alcohol to the body, thus possessing practical application value.
Owner:SICHUAN FUZHENG PHARM CO LTD

Method and system for transdermal alcohol monitoring

A method for monitoring intoxication of a user, the method including: receiving a set of samples from a body region of a user; generating an intoxication metric based on the set of samples; and providing a notification to the user based on the intoxication metric. The method can additionally or alternatively include: modifying operation of the transdermal alcohol sensing device based on the intoxication metric; determining contextual data; maintaining a hydration level of the transdermal alcohol sensing device; and any other suitable processes. A system for monitoring intoxication of a user including a sensor and a housing. The system can additionally or alternatively include any or all of: an inlet, a fastener, an electronics subsystem, a user device, and / or any other suitable component.
Owner:KHN SOLUTIONS LLC

A combined system preparation for preventing and treating alcohol harm and a preparation method thereof

PendingCN122140853ADigestive systemAerosol deliveryFormularyIntoxication alcohol
The application discloses a combined system preparation for preventing and treating alcohol harm, and belongs to the technical field of traditional Chinese medicines. The combined system preparation is composed of sugar-free chewing gum for oral taking and external use acupoint gel ointment. The sugar-free chewing gum is prepared by using homologous medicinal and edible materials such as Flos Puerariae, can be absorbed through oral mucosa, can freshen breath, has the effects of removing alcohol toxicity, refreshing brain, calming nerves, protecting liver and stomach, and the like, relies on natural food seasoning to optimize taste, has mild medicinal properties and is suitable for long-term conditioning, realizes the combination of medicine and food, and achieves the effect of "combining medicine with food". The external use ointment is designed with special formula for five core syndromes, takes the external and internal acupoint matching method as the core, integrates various acupoint matching methods, and realizes the precise correspondence among syndromes, ointments and acupoints. The two can realize double-channel drug delivery, can quickly remove alcohol, protect and nourish viscera from multiple targets, can prevent before drinking, relieve after drinking and long-term conditioning, are in line with the TCM concept of "preventing disease before it occurs", and are suitable for acute drunkenness and long-term drinking population. The preparation process retains active ingredients at low temperature, the ointment adopts modular design, and is suitable for industrial production.
Owner:左耀武

Drunk detection method and device, vehicle-mounted equipment, storage medium and program product

The invention relates to a drunkenness detection method and device, vehicle-mounted equipment, a storage medium and a program product. The method comprises the steps that when a vehicle is started, a head image, collected by an image collecting device on the vehicle, of a main driver on the vehicle and first gas sensing data output by an alcohol sensor on the vehicle are obtained, the head image is recognized, and face information and physiological parameters of the main driver are obtained; and analyzing the first gas sensing data to obtain a first alcohol content of the current air in the vehicle, and then performing drunkenness detection according to the facial information, the physiological parameters and the first alcohol content to obtain a first drunkenness detection result. According to the method, whether the main driver is drunk or not is comprehensively judged by using three different types of data including the sensing data of the alcohol sensor, the facial information of the main driver and the physiological parameters, non-inductive drunkenness detection can be realized, the defect of misrecognition of single type of data can be overcome, and the drunkenness detection accuracy can be greatly improved.
Owner:CHONGQING JINKANG NEW ENERGY VEHICLE CO LTD

Compound biological enzyme preparation for dispelling effects of alcohol and preventing drunkenness and application thereof

The invention discloses a compound biological enzyme preparation for dispelling effects of alcohol and preventing drunkenness and application thereof, and relates to the technical field of biology. The composite biological enzyme preparation comprises the following raw materials: 3-15 of papain, bromelain, alkaline protease, acid protease, pepsin, trypsin, alpha-amylase, lactase, lipase, cellulase, pectinase, glucoamylase, nuclease, nattokinase and serrapeptase. The composite biological enzyme preparation provided by the invention can obviously prolong the drunkenness latency period and greatly shorten the awakening time; the safety performance is excellent, the acute toxicity test shows that the compound meets the actual non-toxic level standard, and the oral administration safety is high. The alcohol effect dispelling and drunkenness preventing product developed by the invention has the core competitiveness of high efficiency, safety and strong adaptability, and has a wide application prospect.
Owner:NANNING PANGBO BIOLOGICAL ENG CO LTD

A casein preparation with delayed alcohol absorption and its use in food products

The application belongs to the field of biotechnology and medical health, and discloses a casein preparation capable of delaying alcohol absorption and application of the casein preparation in food. The application provides a preparation formula taking casein as a core active ingredient in view of the problems of obvious side effects and insignificant effect of existing alcohol elimination products. The casein preparation can form a colloid condensation layer in gastric juice to protect gastric mucosa, delay the absorption speed of alcohol in the gastrointestinal tract, reduce the damage of alcohol to the gastrointestinal tract and liver, and up-regulate the activity of liver ethanol dehydrogenase ADH and acetaldehyde dehydrogenase ALDH to accelerate alcohol metabolism. The casein preparation can reduce the drunken rate after acute alcohol intake, significantly prolong the drunken time, has excellent alcohol absorption delaying effect and eating safety, and is suitable for preparing various alcohol absorption delaying, liver and stomach protecting food.
Owner:SHANGHAI XIMAIS BIOPHARMACEUTICAL CO LTD

Methods and vehicles for preventing drunk driving

This invention discloses a method and vehicle for preventing drunk driving, belonging to the field of vehicle technology. The method includes: a gas detection module sending the detected current alcohol concentration around the driver's seat to a controller. The controller, in response to the current alcohol concentration being higher than a preset alcohol concentration, generates an image acquisition command and sends it to an image acquisition device. The image acquisition device, in response to receiving the image acquisition command, acquires the facial features of the person in the driver's seat according to the command and sends the facial features to the controller. The controller, in response to the facial features meeting a first preset condition, activates a warning control module, wherein the first preset condition indicates that the person is intoxicated. After the warning control module is activated, the vehicle is kept in a parked state. The technical solution provided by this application can restrain drivers' drunk driving behavior and avoid dangerous consequences caused by drunk driving.
Owner:CHERY AUTOMOBILE CO LTD

A composition for preventing and alleviating acute drunkenness

ActiveCN120154698BNervous disorderAntipyreticImmunocompetenceAlcohol breakdown
The present application relates to a kind of compositions for preventing and relieving acute drunkenness, which is prepared from the following raw materials by weight: 30 parts of Gegen, 10 parts of Chengma, 10 parts of Zhupencao, 15 parts of Zexie, 15 parts of Baishu, 30 parts of Fuling, 15 parts of Xianhecao, 15 parts of Gaoliangjiang and 30 parts of Baimaogen.The composition provided by the present application is a multi-target and multi-path protective process for treating acute alcoholism, involving anti-inflammatory, anti-allergic, promoting protein synthesis, immunosuppression, anti-shock, regulating blood lipids and cholesterol, participating in alcohol decomposition and metabolic pathways; affecting transcription factors such as SP1, ESR1, RELA (P65), NF-κb1 and STAT3, which can not only prevent acute drunkenness, but also reduce the harm of alcohol metabolism after drunkenness, including hyperlipidemia, dementia, hypercholesterolemia, fatty liver, cognitive impairment, cardiovascular and cerebrovascular diseases, etc. In addition, it can also protect the cardiovascular, nervous and skeletal systems after drunkenness, regulate immunity and enhance the immune capacity after drunkenness.
Owner:BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIVERSTY

Liquor box (Song liquor seven-star drunk liquor box)

ActiveCN309865884SBiotechnologyWine bottle
1. The name of the design product: wine box (Songjiu Seven Star wine box). 2. The use of the design product: for placing wine bottles. 3. The design points of the design product: in the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view.
Owner:ZHENGZHOU GUOXI LIQUOR CO LTD

Application of lactobacillus reuteri DSM17938 and product of lactobacillus reuteri DSM17938

The invention discloses application of lactobacillus reuteri DSM17938 and a product of the lactobacillus reuteri DSM17938. Aiming at the technical problems that the existing chemical anti-alcohol medicine has side effects and the anti-alcohol effect of common probiotics is unstable, the key point of the technical scheme of the invention is to provide application of a specific strain DSM17938 in preparation of functional foods or medicaments, and the viable organism content of lactobacillus reuteri DSM17938 in the product is 1 * 10 < 9 >-5 * 10 < 10 > CFU / mL or CFU / g; the product can effectively improve the content of alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) in the body, and further improve the total activity of the body, thereby prolonging the drunkenness latency of alcohol gavage mice and shortening the drunkenness sleep time of the mice. The invention also provides yoghurt which is prepared by fermenting the strain and has the effect of increasing the content of alcohol metabolic enzyme, and medicaments such as oral liquid and capsules containing the strain. The main purpose of the invention is to provide a safe, efficient and stable probiotic solution for relieving drunkenness symptoms, promoting alcohol metabolism and protecting the liver.
Owner:GUANGXI MEDICAL UNIVERSITY

Pure traditional Chinese medicine health-care product capable of efficiently, rapidly and directly degrading alcohol concentration in whole drinking process and having effects of preventing and reducing liver and stomach protection caused by drunkenness and preparation method of pure traditional Chinese medicine health-care product

The invention discloses a pure traditional Chinese medicine finished product and a preparation method thereof. The pure traditional Chinese medicine finished product can efficiently and quickly degrade alcohol concentration and prevent and reduce drunkenness. At present, medicines for dispelling the effects of alcohol are divided into chemical medicines and traditional Chinese medicine preparations. The traditional Chinese medicine has the following defects: (1) chemical medicines can aggravate decomposition and metabolism burdens of liver and kidney, and toxic and side effects are great; (2) traditional Chinese medicines have small toxic and side effects, but take effect slowly and are inconvenient to take. (3) on the basis of hangover alleviating and sobering treatment after drunkenness, drunkenness has hurt to human body. And (4) extracting the effective components of the traditional Chinese medicine, applying certain chemical reagents for preparation, mostly adopting intermediates such as paste, powder, particles and the like as compositions, and adopting other media and fillers for the final finished product, so that the effective components are diluted. The traditional Chinese medicine preparation has the following advantages and innovations: 1, a pure traditional Chinese medicine finished product is not used in the preparation process, any chemical is used, and toxic and side effects are avoided; 2, the effect of directly and efficiently degrading alcohol concentration in the whole drinking process is achieved; and 3, drunkenness is mainly prevented and reduced, and drunkenness and sobering treatment is assisted. The harm of drunkenness to a human body is reduced to the greatest extent. And 4, taking is simple.
Owner:汤建明

A polygonum multiflorum thumb extract, its preparation method and use

ActiveCN117281866BAntipyreticAnalgesicsPharmaceutical drugIntoxication alcohol
The application discloses a preparation method of a polygonatum officinale extract. The method uses high-pressure homogenization extraction, macroporous adsorption resin purification and three-phase extraction technology to obtain total flavones and total polysaccharides with high purity. The extract is rich in two categories of chemical components and has the advantages of high extraction efficiency. The application further discloses the use of the polygonatum officinale extract in the preparation of an alcoholism-relieving medicine or health-care food. The polygonatum officinale extract prepared by the application can effectively inhibit the damage of alcohol to the gastric mucosa and the liver, and shorten the drunk maintaining time, and therefore can be used for the preparation of an alcoholism-relieving medicine or health-care food.
Owner:JINJINHAI TECHNOLOGY (CHENGDU) CO LTD

Traditional Chinese medicine composition with hangover alleviating effect and preparation method thereof

PendingCN121243307AAerosol deliveryOintment deliveryDiuresisIntoxication alcohol
The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine composition with a hangover alleviating effect and a preparation method thereof. The traditional Chinese medicine composition comprises 10-50 parts of pueraria flower, 10-50 parts of hyacinth bean flower, 10-50 parts of bamboo shavings, 10-50 parts of folium eriobotryae and 10-60 parts of honey. The traditional Chinese medicine composition disclosed by the invention has the effects of relieving drunkenness, enlivening spleen, clearing heat, promoting diuresis, calming adverse-rising energy, reducing phlegm and arresting vomiting, also has health-care effects in the aspects of protecting liver, protecting gastric mucosa, inducing diuresis and regulating nerves, and can accelerate the metabolic rate of alcohol in a human body and relieve the symptoms of vomiting, dizziness, headache, dysphoria with smothery sensation, difficulty in sleep and the like after drunkenness.
Owner:NINGBO CUIYUAN KANGYI BIOTECHNOLOGY CO LTD

Karaoke equipment

We provide a karaoke machine that can assist users who have consumed alcohol with singing karaoke. [Solution] A karaoke device having a vocal range memory unit that stores the vocal range of each user when sober and when intoxicated; an acquisition unit that acquires the alcohol concentration of the user's breath; an identification unit that identifies pitches that cannot be sung based on the user's sober and intoxicated vocal ranges when the alcohol concentration is above a predetermined value; a determination unit that determines whether the reference pitch of each note in a song matches a pitch that cannot be sung; a setting unit that sets a correction value when the reference pitch of a note in a song matches a pitch that cannot be sung; and a sound output processing unit that, when the user sings a note in a song, emits singing sound based on a singing pitch corrected based on the set correction value.
Owner:DAIICHI KOSHO COMPANY