1209 results about "Cerebro vascular disease" patented technology

This invention concerns the method of extracting salvianolic acid A from Chinese crude drug: danshen root, and the quality control methods and drug combinations, and the application of this drug. It can be used in the preparation of the prevention drugs for cardiovascular disease, liver damage, liver fibrosis, pulmonary fibrosis and other.

An implantable medical device is provided for the suppression or prevention of pain, movement disorders, epilepsy, cerebrovascular diseases, autoimmune diseases, sleep disorders, autonomic disorders, abnormal metabolic states, disorders of the muscular system, and neuropsychiatric disorders in a patient. The implantable medical device can be a neurostimulator configured to be implanted on or near a cranial nerve to treat headache or other neurological disorders. One aspect of the implantable medical device is that it includes an electronics enclosure, a substrate integral to the electronics enclosure, and a monolithic feed-through integral to the electronics enclosure and the substrate. In some embodiments, the implantable medical device can include a fixation apparatus for attaching the device to a patient.

The present invention discloses a slowly-released oral medicine preparation which is made up by using breviscapine as main raw material and has the functions of promoting blood circulation and removing blood stasis, removing obstruction in the channels to relieve pain for curing angiocardiopathy and cerebrovascular disease with obvious therapeutic effect and its preparation method. Said slowly-released tablet (by one tablet) contains 60-120 mg of breviscapine, 20-75 mg of diluent, 50-150 mg of filling agent and 10-50 mg of slow release material. Said invention also provides its preparation method and concrete steps.

The invention relates to a brain vascular blood circulation dynamic analysis method and the apparatus thereof. According to the cerebral circulation vascular bed anatomical model, an equivalent network model which comprises 12 pipeline units simulating the brain circulation blood dynamics is built, and the relevant parameter calculation formulas are confirmed, by utilizing the formulas, the flow rate waveform and the value inside the cartid artery, the pressure waveform, the blood pressure of the body, the diameter of the blood vessel, the flow rate waveform and the valve of the vertebral artery and the front, the middle and the rear parts on two sides inside the skull, and the characteristic and the parameter of the cartid artery and each blood vessel section inside the skull can be determined, the apparatus designed by the invention can be performed, the detecting system comprises the vessel diameter detecting of the cartid artery outside the skull, the blood pressure detecting, theblood flow rate detecting of the cartid artery outside the skull, the pressure waveform detecting of the cartid artery outside the skull, and the blood flow rate detecting on the artery inside the skull; the control system comprises a control module and a power supply module; the calculation and analysis system comprises a host computer, a peripheral equipment, and an analog-digital converter, the invention can fully analyze the brain circulation dynamic characteristic, thereby having notable effect on the early stage and the ultra early stage diagnosis and therapy of the brain vascular illness.

Methods of treating metabolic diseases and disorders using a FGF21 polypeptide are provided. In various embodiments the metabolic disease or disorder is type 1 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, diabetic nephropathy, neuropathy, retinopathy, ischemic heart disease, peripheral vascular disease and cerebrovascular disease

A hemodynamic method and instrument for early diagnosis of cerebrovascular diseases features that the Doppler probe and ultrasonography B are used to detect the blood flowing speed, the ultrasonography B is used to detect the physical characteristics of blood vassel, the diameter and wall thickness of blood vessel are measured to obtain the flow of blood in the vessel, and a pressure probe is used to detect blood pressure.

The invention relates to flour suitable for patients with diabetes mellitus. The flour is prepared by uniformly stirring powder made of traditional Chinese medicines, such as rhizoma polygonati, kudzu-vine root, Chinese yam, tuckahoe, semen coicis, mulberry fruit, frosted mulberry leaf, raw hawthorn and semen euryales and the mixed flour of different grain, such as soya bean, string bean, cow peaand wheat which are beneficial to the patients with diabetes mellitus in a certain proportion and can be used for producing various foods suitable for the patients with diabetes mellitus to have as aprincipal food. The special meal flour has the obvious effects of systemically adjusting glucose metabolism, lightening the pancreatic island load, improving carbohydrate tolerance, microcirculation and the function of the visceral organ, reducing blood fat and blood viscosity and eliminating radicals. The special meal flour is suitable for the patient withs diabetes mellitus, adiposity, hyperlipemia, high blood viscosity, adiposis hepatica, hypertension and heart cerebrovascular disease and middle-aged and old people to have as the principal food.

The invention relates to a baked fast food and a method for making the same, in particular to a trtary buckwheat potato crisp containing nutritional ingredients such as trtary buckwheat and the like and having dual effects of nutrition and health care and a method for making the same. The food is characterized by the addition of trtary buckwheat having the effects of preventing cardiovascular and cerebrovascular diseases and protecting health; and the food is made through a special fabrication process and has both nutritive value and health care function.

The present invention discloses a medicine for curing angiocardiopathy and cerebrovascular disease. It is formed from ginseng stem and leaf saponin extracted from ginseng stem and leaf and peony total glycoside extracted from peony as raw material. Said medicine composition not only can promote blood circulation and remove stasis and relieve inflammation and stop pain, but also can supplement qi and promote the production of body fluid, and can raise immunity of human body, so that its therapeutic effect is greatly raised.

The invention belongs to the technical field of traditional Chinese medicine, particularly relates to a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine for treating the cardiovascular and cerebrovascular diseases is characterized being prepared from the following raw materials in parts by weight: 2 to 4 parts of radix panacis quinquefolii, 1 to 3 parts of dried human placenta, 5 to 7 parts of radix salviae miltiorrhizae, 5 to 7 parts of herba rhodiolae, 1 to 3 parts of schisandra chinensis fructus, 4 to 6 parts of head of angelica sinensis, 4 to 6 parts of Chuanxiong rhizoma, 3 to 5 parts of flesh of polygalae radix, 4 to 6 parts of hirudo, 4 to 6 parts of radix notoginseng, 4 to 6 parts of fried spina date seed, 7 to 9 parts of herba cistanche, 1 to 3 parts of saussurea involucrate, 3 to 5 parts of ganoderma lucidum spore, 2 to 4 parts of dendrobium officinale, 2 to 4 parts of grilled polygonum multiflorum, 4 to 6 parts of radix puerariae, 4 to 6 parts of rhizoma gastrodiae, and 9 to 11 parts of herba bidentis pilosae. Various herbs are matched to complement each other and to have functions for tonifying Qi, promoting blood circulation to remove blood stasis and activating main and collateral channels. The traditional Chinese medicine is widely used for treating the cardiovascular and cerebrovascular diseases.

The present invention relates to a Soy daidzin composition and its preparation method and application. It provides three compounds containing isoflavone glucoside which can be used for preparing medicine for curing climacteric syndrome due to female hormone deficiency and middle-aged and senile obtiterating angiocardiopathy and cerebrovascular disease. Said composition contains isoflavone glucoside compound, i.e. diadzin, soyabean flaving glucoside and genistin, and three kinds of isoflavone are 90%-100% of the composition, and the ratio of three isoflavone glucoside is 2-3:1-2:3-4. It can be made into various dosage forms of medicine preparation, and its preparation method includes the following steps: extracting soyabean with ethyl alcohol, concentrating, extracting with petroleum ether, vacuum drying to obtain dried powder.

The invention relates to the food scientific and technical field, and aims at providing a seafood flavoring prepared by using shrimp shell and a preparation method. The seafood flavoring is prepared by compounding the following components by weight percentage: 60%-70% of shrimp shell extract, 8%-15% of monosodium glutamate, 12%-20% of salt, 5%-10% of white sugar, 0.2%-0.5% of clove powder, 0.3%-0.6% of pepper, 0.2%-0.5% of fennel powder and 0.5%-1.0% of anti-oxidant. The components of the present invention have the advantages of reasonable compatibility, low production cost, good mouthfeel, delicious taste and abundant nutrients. The seafood flavoring contains rich active peptide, carnosine, amino acid, nucleotide, vitamin and trace elements, particularly to astaxanthin with the functionsof antioxidation, aging resistance, anti-tumor, cardio-cerebrovascular disease prevention and the like, the seafood flavoring is a good marine organism product.

The peony seed oil is rich in a great amount of unsaturated fattyacid, alpha-linolenic acid with maximal content in the peony seed oil is essential to the human body and has an important effect on improving the intelligence, protecting the vision and preventing cardiovascular and cerebrovascular diseases. But a majority of unsaturated fattyacid is easily oxidized, and the nutritional value of the peony seed oil is reduced. A preparation process of the water-soluble peony seed oil powder comprises the following steps of dissolving a wall material and an emulsifier into distilled water, stirring the wall material, the emulsifier and the distilled water until being adequately dissolved, slowly adding the peony seed oil to carry out the embedding at the temperature of 30 to 90 DEG C according to the ratio of the peony seed oil to the wall material of 1: 10 to 5: 10, adequately mixing the solution, homogenizing and emulsifying the mixture under the pressure condition of 100 to 1000 bar to obtain an emulsified solution, and carrying out spray drying or freezing drying on the emulsified solution, thus preparing the water-soluble peony seed oil powder product. The water-soluble powder product has the advantages that the oxidation of the peony seed oil can be prevented, convenience in carrying can be realized and the like, and after the water-soluble peony seed oil powder is added into the drinking water, a stable emulsion system with good dispersion can be formed. The water-soluble powder can be used as a mate for the drink such as coffee, contains no trans-fatty acids and is safe and nutritional.

The invention relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases, mainly containing one or more of Salvia miltiorrhiza, folium ginkgo, panax notoginseng, kudzuvine root Pueraria lobata, rhizoma ligustici wallichii, hawthorn and lotus leaf. The preparation method comprises the steps of selecting one or more of the Salvia miltiorrhiza, the folium ginkgo, the panax notoginseng, the kudzuvine root Pueraria lobata, the rhizoma ligustici wallichii and the hawthorn and lotus leaf, decocting, extracting active ingredients and concentrating the extracting solution to a certain concentration to obtain the Chinese traditional medicine preparation. In addition, the concentrated solution can be further made into capsules, tablets, granules, oral liquid, pills, pulvis, injection and sustained and controlled release preparations. Toxicologic and pharmacologic agent experiments show that the invention has no toxic side effect, is safe to use, has the functions of promoting blood circulation, remove blood stasis, reducing fat, freeing channels and eliminating phlegm and is suitable for phlegm stasis internal-block type cardiovascular and cerebrovascular diseases.

The invention discloses a novel conjugate composed of a hydrophilic polymer and resveratrol, a pharmaceutical composition including the conjugate, their preparation methods and applications in the preparation of drugs for treating tumor, diabetes and cardio cerebrovascular disease, wherein the hydrophilic polymer is selected from the group consisting of polyethylene glycol, polyglutamic acid, polyaspartic acid, polypropylene glycol, polyvinyl alcohol, polypropylene morpholine, polyethylene glycol-amino acid oligopeptide and their copolymer. Through modification of the hydrophilic polymer, a bound drug can be protected, stability and water solubility of the conjugate are raised, and active period of the conjugate in organisms is prolonged.

The invention relates to a kind of ligustrazine derivant, preparation method and medicinal compound and its application, belonging to chuanxiong rhizome derivant medicine technique. The structure general formula is as that: Ar is hydroxybenzene, fluorophenyl, chlorphenyl, methylbenzene, methoxybenzene, nitrobenzene, cyanobenzene, furan group, ligustrazine or thiofuran. Said preparation method comprises following steps: mixing intermediate 2- chloromethyl- 3, 5, 6- trimethyl pyrazine and halogenated benzyl, triethyl phosphite; heating and refluxing, adding waterless tetrahydrofuran and NaH at tetrahydrofuran bath condition, dropping mixing solution of aromatic aldchyde and waterless tetrahydrofuran, stirring, extracting, drying, filtering, steaming to remove disslovant, separating residues with fast column chromatography, recrystallizing with methanol, and getting ligustrazine derivant. Said product and medical findings can be used to produce medicinal compound, and medicine for preventing angiocardiopathy and cerebrovascular diseases such as ischemic disease, atherosclerosis and coronary disease.

The invention discloses functional camellia oil, which is obtained by mixing, stirring and filtering raw materials comprising the following ingredients in parts by mass: 928.8 to 989.3 parts of camellia oleifera seed oil, 10 to 70 parts of plant sterol ester, 0.1 to 0.7 part of rosemary and 0.1 to 1 part of vitamin E. The functional camellia oil has the advantages that the stability is good, the shelf life is long, the effect of obviously reducing blood cholesterol, triglyceride and low-density lipoprotein cholesterin is realized, the cardiovascular and cerebrovascular diseases can be effectively prevented, and good stability is realized during high-temperature cooking.

The present invention discloses a pharmaceutical composition for the treatment of cardiovascular and cerebrovascular diseases which comprises Radix Salviae Miltiorrhizae extract 5.0%-70.0%, Radix Notoginseng extract 10.0%-85.0%, Radix Astragali extract 5.0%-70.0%, and Bomeol or oil of Lignum Dalbergiae Odoriferae 1.0%-15.0%. The composition is active against cerebral ischemia and myocardial ischemia. The effects are superior to total phenic acid of Radix Salviae Miltiorrhizae or total saponin of Radix Notoginseng respectively, or the combination thereof. The composition of the invention can provide various kinds of preparations by the addition of various accessories. Thus the invention provides a more effective and convenient composition of TCM effective sections and its preparations.

The present invention provides a preparation method of a health-care blueberry beverage, and includes the following raw materials: blueberries, herba dendrobii, ginger, schisandra chinensis, sugar stevia leaves, Chinese wolfberries, guavas, carrots, sapodilla, grapes, actinidia chinensis, haws, bitter apricot kernels, corn, oats, soybeans and green tea. The beverage contains a variety of effective ingredients and nutritional ingredients including polysaccharides, flavonoids, flavonoids, saponins, peptides, vitamins, etc. The beverage can enhance and regulate immune function of human body, protect liver and improve eyesight, regulate intestinal microflora, resist aging, protect skin and beautify appearance, eliminate fatigue, prevent cardiovascular and cerebrovascular diseases, etc.