The invention discloses an integrated traditional Chinese and western medicine medicine for treating atrophic gastritis and a preparation method thereof, belonging to the technical field of medicine; the raw materials of the active ingredients of the medicine integrated traditional Chinese and western medicine are composed of: pepsin, metoclopramide, rotundine, Ulmus chinensis, Kapok root, Osmanthus fragrans, Yellow bud cabbage, Shannai, White leaves, Bergamot, Longzi, Bailiang rice, Podocarpus pine fruit, Hanberry root, Orange peel and Mountain pepper root; Chinese and Western medicine of the present invention The combined medicine has a unique curative effect on the treatment of atrophic gastritis, and the preparation process is simple, the curative effect is remarkable, the absorption effect is good, it is convenient to take, safe and reliable, it is not easy to relapse after being cured, the cost is low, and it can achieve the purpose of treating both symptoms and root causes. Yin benefits the stomach, warms the middle and invigorates the spleen, relieves inflammation and relieves pain, regulates qi and activates blood circulation.