Conjugates containing hydrophilic spacer linkers

a technology of hydrophilic spacer linkers and conjugates, which is applied in the direction of drug compositions, peptides/protein ingredients, antibacterial agents, etc., can solve the problems of complex approaches and adverse side effects of the currently available chemotherapeutic agents and radiation therapy regimens
US20140073761A1Pending Publication Date: 2014-03-13ENDOCTYE INC
0 Cites 13 Cited by

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ENDOCTYE INC
Publication Date
2014-03-13

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

Described herein are compositions and methods for use in targeted drug delivery using cell receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in imaging, diagnosing, and / or treating diseases and disease states caused by pathogenic cell populations.
Need to check novelty before this filing date? Find Prior Art

Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of priority under 35 U.S.C. §119(e) of U.S. provisional patent application Ser. Nos. 60 / 946,092 and 61 / 036,186, filed Jun. 25, 2007 and Mar. 13, 2008, respectively; the disclosures of which are incorporated herein in their entirety by reference.TECHNICAL FIELD

[0002] The present invention relates to compositions and methods for use in targeted drug delivery. More particularly, the invention is directed to cell-surface receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations and to methods and pharmaceutical compositions that use and include such conjugates.BACKGROUND

[0003] The mammalian immune system provides a means for the recognition and elimination of tumor cells, other pathogenic cells, and invading foreign pathogens. While the immune system normally provides a strong line of defense, there are many instanc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More