36 results about "Chloroformate" patented technology

The application belongs to the technical field of chemical synthesis, and particularly relates to a preparation method of diisopropyl peroxydicarbonate and application of the diisopropyl peroxydicarbonate. The preparation method comprises the following steps: firstly, isopropyl chloroformate and an ester-soluble organic solution are added into a three-necked flask, stirring is started, hydrogen peroxide solution is added, when the temperature of the mixture in the flask is stabilized at-5 DEG C, sodium hydroxide solution is slowly added into the three-necked flask, and the time and temperature in the reaction process are controlled; finally, the organic phase is separated, washed with water, dried with anhydrous sodium sulfate, and obtained. The preparation method is safe and controllable, the yield of the diisopropyl peroxydicarbonate is high, the stability is good, the diisopropyl peroxydicarbonate can be directly used for the preparation of polyvinylidene fluoride, a chain transfer agent is not needed, polymerization can be carried out under low-temperature conditions, the molecular chain regularity of the polyvinylidene fluoride is improved, abnormal structures are few, the crystallinity is high, and the comprehensive performance is good.

The invention discloses a positive pole piece and a preparation method thereof, a diaphragm-free battery and a battery. The positive pole piece comprises a positive pole current collector and a positive pole active material layer arranged on at least one side of the positive pole current collector, the positive pole active material layer comprises a polymer, and the polymer is formed by polymerizing at least one of small molecules of the following raw material components: vinylethylene carbonate, vinylene carbonate, 2, 3, 4-trimethyl-1, 3-pentanedione, 2, 3, 4-trimethyl-1, 3-pentanedione and 2, 3, 4-trimethyl-1, 3-pentanedione. The adhesive is prepared from 2, 4-hexadienoic acid, allyl trifluoroacetate, diethyl allylmalonate, allyl methacrylate, allyl chloroformate, allyl phenylacetate, allyl acetate, allyl 4-hydroxybenzoate and allyl phenoxyacetate. The adhesive is prepared from the following raw materials: 1, 4-hexadienoic acid, allyl trifluoroacetate, diethyl allylmalonate, allyl methacrylate, allyl chloroformate, allyl phenylacetate, allyl acetate, allyl 4-hydroxybenzoate and allyl phenoxyacetate. The positive pole piece provided by the invention comprises the polymer, so that the interface impedance can be reduced, and the rate capability of the battery can be improved.

This invention belongs to the field of chloroformate synthesis technology, and particularly relates to a continuous preparation method of chloroformates, comprising the following steps: 1) feeding the reactant raw material alcohol and phosgene together into a synthesis tower via an absorption tower for reaction, generating crude chloroformate and byproduct hydrogen chloride; 2) sending the crude chloroformate formed in step 1) to a degassing tower, returning the phosgene removed from the degassing tower to the synthesis tower for further reaction, and then distilling the chloroformate after phosgene removal into a purification system to obtain the target product chloroformate; 3) sending the byproduct hydrogen chloride formed in step 1) into an absorption tower for washing with the raw material alcohol and then into the tail gas system. The beneficial effects of this invention are: it realizes continuous production of chloroformate products through synthesis and deacidification, improves the synthesis reaction rate, and shortens the deacidification time; simultaneously, through the recovery and recycling of phosgene, it reduces raw material consumption and forms a clean, inherently safe, automated production process.

Biodegradable, controlled release microcapsules whose microcapsule walls comprise the reaction product of fractured plant proteins with isocyanates and / or bis- or poly-chloroformates.

The invention discloses anti-mildew plastic for a packaging container and a preparation method of the anti-mildew plastic, and relates to the technical field of plastic. The plastic is prepared from the modified biochar and the modified polyethylene; wherein 3, 5-diformylphenylboronic acid, 5-nitro-2-(oxiranyl methoxy) acetophenone, ethynyl magnesium bromide, isobutyldichlorosilane, hydroxylamine hydrochloride, ammonium salt and 3-butenyl chloroformate are used for synthesizing an anti-aging substance, then the anti-aging substance and polyethylene are subjected to cross-linking modification, an ultraviolet absorption group, a silicon-carbon bond and a boron-carbon bond are introduced into a polyethylene side chain, and the anti-aging substance is prepared. While the photo-thermal aging of the plastic is prevented, the barrier property of the plastic is improved; the biochar is modified by aminopropyl methyl dimethoxysilane, N, N-diethyl-p-aminobenzaldehyde, 11-chlorodecanoic acid and chitosan, antibacterial groups are generated on the surface of the biochar, and the biochar and modified polyethylene can be stacked in order, so that movement of water vapor and oxygen is prevented, and the anti-mildew effect of the plastic is improved.

This invention belongs to the field of peroxide preparation technology, specifically relating to a heat exchange device and method for preparing peroxides. The heat exchange device includes heat exchange tubes disposed within a reaction vessel, with several heat exchangers mounted on the heat exchange tubes. Each heat exchanger includes several external fins spaced apart on a fixed plate. The fixed plate has grooves that mate with the heat exchange tubes, and the heat exchange tubes are disposed within these grooves. The peroxide preparation method involves stirring a desensitizer, a catalyst, and an oxidant together, followed by the addition of an alkyl acyl chloride or an alkyl chloroformate to continue the reaction. After the reaction is complete, a crude product is obtained. The crude product is then washed and separated to obtain the peroxide. This invention utilizes the high-efficiency heat transfer performance of the heat exchanger, thereby enabling stable preparation of peroxide products, reducing the reaction time, and improving the conversion efficiency from initial raw materials to peroxide products.

The present application relates to a kind of aryl carboxylate compounds and its preparation method, preparation method includes the following steps: S1, under inert atmosphere, chloroformate or its derivative, aryl iodine, ligand, reducing agent, additive and catalyst are dissolved in solvent, obtain the reaction body solution;S2, the reaction body solution obtained in S1 step is stirred, obtain the aryl carboxylate compound of structural general formula as shown in III, wherein, R 1 Group is selected from H, 4-trifluoromethyl, 4-methoxy, 4-methyl formate in any one of methyl group, R 2 It is selected from 4-trifluoromethyl, 4-acetyl, 4-methyl formate in any one of methyl group.Compared with prior art, the present application uses chloroformate or its derivative, aryl iodine as substrate, aryl carboxylate compound is prepared, reaction condition is mild and substrate is widely adaptable, yield is as high as 80%.And raw material cost is low and easy to obtain, preparation condition is simple and also easy to realize.

This invention belongs to the field of nanomedicine technology, specifically relating to a pH / hypoxia dual-responsive polymer, nanomicelles, their preparation method, and applications. The pH / hypoxia dual-responsive polymer is a hydroxyethyl deacetylated chitosan modified with p-nitrobenzyl chloroformate and cinnamaldehyde. Ropivacaine is loaded onto it and prepared into nanomicelles for use as a drug delivery system after tumor surgery. Due to its acid sensitivity and hypoxia response, it can intelligently identify the tumor microenvironment, achieving precise drug delivery.

The application relates to a synthesis method for constructing 2,4-imidazolidinedione compounds in a DNA coding compound library. The method takes 2-amino-N-acetamide compounds of On-DNA and p-nitrophenyl chloroformate as raw materials, reacts under the action of alkali, and obtains 2,4-imidazolidinedione compounds. The method has the advantages of mild reaction condition, simple operation, good substrate universality, good product yield and suitability for DNA coding compound synthesis in a multi-well plate.

The present application relates to the synthesis of pesticide compounds, in particular to a method for preparing a pyrasulfotole intermediate. The method comprises: (1) using p-chlorotoluene as a raw material, through nitration, chlorination, hydrolysis, or chlorination, hydrolysis, nitration, to obtain 3-nitro-4-chlorobenzaldehyde, (2) fluorination and reduction of 3-nitro-4-chlorobenzaldehyde to obtain 4-fluoro-3-amino benzaldehyde; (3) 4-fluoro-3-amino benzaldehyde is then contacted with chloroformate for reaction, and then chlorination to obtain compound IV; (4) compound IV is contacted with trifluorobutanamine ester under alkaline conditions for reaction to obtain compound I. The process for preparing compound I avoids using expensive raw material 2-chloro-4-fluorobenzoic acid, effectively reduces the cost of raw materials, reduces the three wastes generated in the process, and at the same time, the total yield of the reaction is high, and it is suitable for industrial mass production.

The invention discloses a preparation method of dodecyl chloroformate, which comprises the following steps: heating dodecanol to melt the dodecanol into a liquid state, introducing phosgene for reaction, reducing the reaction temperature to 0-20 DEG C in the reaction process, continuing the reaction until the content of the dodecanol in the reaction system is less than 0.5%, stopping introducing the phosgene, and keeping the temperature to obtain a reaction liquid; and heating the reaction liquid to 30 DEG C or above, introducing nitrogen, and removing impurities in the reaction liquid to obtain dodecyl chloroformate. Compared with the conventional method, the preparation method of dodecyl chloroformate can effectively improve the reaction conversion rate and selectivity by optimizing the reaction temperature of each stage in the reaction process, and can quickly and simply prepare high-yield and high-purity dodecyl chloroformate, the content is greater than or equal to 98%, the yield is greater than or equal to 98%, the product competitiveness can be improved, and the method is suitable for industrial production. The industrial application is convenient to realize and the industrial practicability is high.

The application discloses a method for continuously synthesizing isooctyl chloroformate, which comprises the following steps: preparing a continuous reaction device which comprises a photochemical tower, a transfer kettle and a chase light tower which are communicated with each other, feeding isooctanol and phosgene into the photochemical tower to perform a reaction, overflowing the obtained esterification liquid to the transfer kettle, performing gas-liquid separation on the obtained tail gas outside the tower, and feeding the liquid light into the tower; controlling the temperature of the transfer kettle at 30-40 DEG C, feeding the esterification liquid into the chase light tower after the transfer kettle collects a certain amount of esterification liquid, controlling the temperature of the chase light tower at 40-80 DEG C, feeding nitrogen into the chase light tower to perform chase light, and collecting high-purity isooctyl chloroformate in the chase light tower, wherein the content of the isooctyl chloroformate is greater than or equal to 99%, and the yield is greater than or equal to 97%. The method realizes continuous production under the premise of ensuring the quality and yield of the product, has small production land occupation, small liquid holdup of the reaction system, small risk, high production efficiency, easily controlled process conditions, little waste, accords with the green and environmental protection production concept, and is suitable for industrial production.

The invention belongs to the technical field of diisocyanate preparation, and particularly relates to a method for preparing diisocyanate from dihydric alcohol. The method for preparing diisocyanate from dihydric alcohol comprises the following steps: reacting dihydric alcohol with phosgene to generate aliphatic alkane diol di (chloroformate); the method comprises the following steps: heating and decomposing aliphatic alkane diol di (chloroformate) into dichloroalkane; enabling the dichloroalkane to react with liquid ammonia to generate aliphatic primary diamine; and reacting the aliphatic primary diamine with phosgene to generate diisocyanate. According to the method, low-cost 1, 4-butanediol or 1, 5-pentanediol is used as a raw material, diisocyanate is prepared through phosgenation, thermal decomposition, ammonification and secondary phosgenation, the technical effects of mild reaction conditions, high yield and reduction of raw material cost are achieved, meanwhile, reaction byproducts can be recycled, and the method is suitable for industrial production. The technical problems that a traditional process depends on an expensive diamine raw material, reaction conditions are harsh, and continuous production is difficult are solved.

The invention belongs to the field of organic matter preparation, and particularly relates to a preparation method of 9-fluorenyl methyl-N-succinimido carbonic ester, which comprises the following steps: dissolving N-hydroxysuccinimide, mixing with dried chloroformic acid-9-fluorenyl methyl ester and silicon-based solid alkali to react, quenching and washing after the reaction is completed, drying and purifying to obtain the 9-fluorenyl methyl-N-succinimido carbonic ester. The 9-fluorenyl methyl-N-succinimido carbonic ester is subjected to a reaction to obtain 9- The solid alkali is doped with ester groups. According to the method, the high-quality and high-purity product can be obtained, the requirement of a high-precision experiment for the product purity can be met, and the method is easy to operate and suitable for industrial popularization.

The application belongs to the field of organic matter preparation, and particularly relates to a preparation method of 9-fluorenylmethyl-N-succinimidyl carbonate, wherein N-hydroxy succinimide is dissolved and mixed with dry chloroformate-9-fluorenylmethyl ester and a silicon-based solid base for reaction, water is used for quenching and washing after the reaction is completed, and 9-fluorenylmethyl-N-succinimidyl carbonate is obtained after drying and purification; an ester group is doped on the solid base. The method can obtain high-quality and high-purity products, can meet the demand of high-precision experiments on product purity, and is simple to operate and suitable for industrial promotion.

Biodegradable, controlled release microcapsules whose microcapsule walls comprise the reaction product of fractured plant proteins with isocyanates and / or bis- or poly- chloroformates.

This invention belongs to the field of organic synthesis technology and relates to a method for preparing (S)-4-(2,4-difluorophenyl)-2-(hydroxymethyl)pent-4-en-1-yl isobutyrate. 2,4-Difluoroiodobenzene reacts sequentially with allyl alcohol and tert-butyl chloroformate to obtain 2-(2,4-difluorophenyl)allyl tert-butyl carbonate. Under the action of a palladium catalyst and Sadphos chiral phosphine ligand, the 2-(2,4-difluorophenyl)allyl tert-butyl carbonate undergoes alkylation and reduction to obtain (S)-4-(2,4-difluorophenyl)-2-(hydroxymethyl)pent-4-en-1-yl isobutyrate. This invention utilizes a palladium catalyst and Sadphos chiral phosphine ligand to precisely construct a chiral center in one step, achieving an enantioselectivity of up to 99.4% and an overall yield of 65-70%. The operation is simple, the catalyst is recyclable, significantly reducing production costs and making it suitable for industrial production.

The invention discloses a method for preparing fluoroformate, which comprises the following steps: by taking chloroformate as a raw material and hydrogen fluoride as a fluorination reagent, mixing chloroformate steam and hydrogen fluoride gas, and performing gas-phase catalysis on the chloroformate and hydrogen fluoride to generate fluorination reaction through a fixed bed reactor filled with a catalyst to obtain the fluoroformate, the catalyst is characterized in that at least one of active components of lithium fluoride, potassium fluoride, sodium fluoride, rubidium fluoride or cesium fluoride is loaded on at least one of carriers of activated carbon, aluminum fluoride, magnesium fluoride, ferric fluoride, chromium fluoride and zinc fluoride, the mass percentage ratio of the active components to the carriers of the catalyst is 10-50%: 50-90%, the reaction temperature is 200-400 DEG C, and the retention time is 10-60 s. The method has the advantages of greenness, high efficiency, continuous catalysis and the like.

The utility model discloses an isooctyl chloroformate continuous production device, the device comprises a synthesis unit and a deacidification unit which are communicated through a pipeline, the synthesis unit comprises a photochemical tower, a tail gas condenser and a crude product buffer tank, the side part of the photochemical tower is provided with an isooctyl alcohol inlet, a liquid light inlet and a crude product outlet, the crude product outlet is connected with a crude product buffer tank through a pipeline, the bottom of the tail gas condenser is provided with a shared port of a tail gas inlet and a liquid-light outlet, and the liquid-light outlet is connected with a liquid-light inlet of the photochemical tower through a liquid-light backflow pipeline; the deacidification unit comprises a falling film evaporator, a gas-liquid separation tank and a finished product temporary storage tank, the top of the falling film evaporator is communicated with the crude product buffer tank through a pipeline, the lower side of the falling film evaporator is communicated with the gas-liquid separation tank through a pipeline, and the bottom of the falling film evaporator is communicated with the top of the finished product temporary storage tank through a pipeline. The device can realize continuous synthesis and deacidification of isooctyl chloroformate, and is low in phosgene consumption, high in product yield, safe and environment-friendly.

This application relates to the technical field of organic light-emitting materials, and particularly to a chiral light-emitting molecule and its preparation method, as well as a chiral light-emitting liquid crystal. The preparation method of the chiral light-emitting molecule includes the following steps: S1: Menthyl chloroformate, 4-phenol-2,1,3-benzothiadiazole, palladium catalyst, and acid-binding agent are sequentially added to a flask, followed by the addition of an organic solvent for dissolution and thorough stirring to obtain a mixture; S2: The mixture is injected into a nitrogen-filled reaction vessel, heated to 70–95°C, reacted for 5–10 hours, and then separated and purified to obtain the chiral light-emitting molecule. Compared with traditional preparation methods such as alkylation, acylation, dehydration, and ring-opening methods, the preparation method of this application significantly shortens the reaction time while increasing the yield; furthermore, this method is simple to operate, the reaction is mild, and it can be carried out under conventional laboratory conditions, reducing the cost of chiral light-emitting molecules.

The reaction kettle structure comprises a kettle body, a liquid pump is arranged at the outer top of the kettle body, an air pump is arranged at the outer bottom of the kettle body, a liquid inlet of the liquid pump is communicated with a liquid conveying pipeline, a liquid outlet of the liquid pump is communicated with a liquid inlet pipe, and the tail end of the liquid inlet pipe downwards extends into the kettle body and is rotationally connected with a liquid spraying pipe. The peripheral side of the lower part of the liquid spraying pipe is communicated with a plurality of liquid spraying branch pipes, the bottom ends of the liquid spraying pipe and the liquid spraying branch pipes are communicated with liquid spraying nozzles, an air inlet of the air pump is communicated with an air conveying pipeline, an air outlet of the air pump is communicated with an air inlet pipe, and the tail end of the air inlet pipe upwards extends into the kettle body and is rotationally connected with an air spraying pipe; a guide rail is arranged on the top in the kettle body, an electric sliding block is arranged on the guide rail in a sliding mode, the bottom end of the electric sliding block is fixedly connected with an L-shaped connecting rod, and the tail end of the connecting rod is fixedly connected with a rotating frame. According to the utility model, the hedging contact of alcohol and phosgene and efficient and high-quality stirring can be realized, and the reaction efficiency and quality are higher.

This invention belongs to the field of compound synthesis technology, specifically relating to a method for synthesizing biphenylhydrazine, comprising the following steps: (1) mixing isopropyl chloroformate and hydroxylamine hydrochloride in solvent a, and reacting under certain temperature and alkaline conditions to obtain intermediate 1; (2) mixing intermediate 1 with a hydrocarbon sulfonyl halide in solvent b, and reacting under certain temperature and alkaline conditions to obtain intermediate 2; (3) mixing intermediate 2 with 3-amino-4-methoxybiphenyl in solvent c, and reacting under certain temperature and alkaline conditions to obtain biphenylhydrazine. This invention provides a novel method for synthesizing biphenylhydrazine. The synthesis of biphenylhydrazine in this application uses new raw materials and intermediates, which has the advantages of inexpensive raw materials, short synthesis route, mild reaction conditions, high yield, and ease of industrial production.

A system and method of making a silylcarbonate compound, the method including reacting trialkylsilylalcohol with alkyl chloroformate in the presence of a base at an elevated temperature to form the silylcarbonate compound.

The invention discloses a method for detecting related substances in n-amyl chloroformate by a GC (Gas Chromatography) method, and belongs to the technical field of chemical engineering and pharmacy, the related substances in the n-amyl chloroformate are detected by a gas chromatography method, and temperature programming is adopted: the initial temperature is maintained for 18 minutes at 50 DEG C, the temperature is raised to 290 DEG C at 20 DEG C / min and maintained for 20 minutes, a constant flow mode is adopted, the flow rate is 2.0 ml / min, the split ratio is 10: 1, the temperature of a sample inlet is 200 DEG C, and the flow rate is 2.0 ml / min; the temperature of a hydrogen flame ionization detector is 290 DEG C, the content of 3-methylbutanol, 2-methylbutanol, n-amyl alcohol, 2-methylbutyl chloroformate and 3-methylbutyl chloroformate in n-amyl chloroformate can be effectively separated and quantitatively detected, and the method is simple and convenient to operate, high in specificity, high in sensitivity and accuracy, good in linearity, high in sensitivity and high in accuracy, and can be used for detecting the content of 3-methylbutanol, 2-methylbutanol, n-amyl alcohol, 2-methylbutyl chloroformate and 3-methylbutyl chloroformate in n-amyl chloroformate. And the quality of the n-amyl chloroformate product can be effectively controlled.

The present application belongs to the field of chemical analysis test, and particularly relates to a phenyl thiochloroformate-based resorcinol fluorescent probe for detecting biological amine. The resorcinol and phenyl thiochloroformate are reacted for 4-5 hours under the catalysis of N,N-diisopropyl ethylamine to obtain the target fluorescent probe. The fluorescent probe has the characteristics that the easily-obtained raw materials are used, and the thioester group structure is integrated into the fluorescent probe molecule through one-step reaction. The synthesis method is simple, the reaction condition is easy to control, and the product is convenient to purify. The fluorescent probe has superior performance in the detection of biological amine, high sensitivity and strong selectivity, and can rapidly and accurately identify biological amine in various solvents such as deionized water, aqueous solution of tris(hydroxymethyl) aminomethane hydrochloride, aqueous solution of cetyltrimethylammonium bromide, aqueous solution of sodium dodecyl sulfate or dimethyl sulfoxide solution, which provides a good precondition for the practical application of the fluorescent probe in biological samples.

The invention discloses a leaf alcohol carbonate precursor fragrance spice, and a synthesis method and application thereof. The method comprises the following steps: reacting dimethyl malate with triphosgene and pyridine to obtain dimethyl malate chloroformate; the method comprises the following steps: dissolving leaf alcohol in CH2Cl2, adding alkali DMAP, then adding dimethyl malate chloroformate, and reacting to obtain dimethyl malate-leaf alcohol carbonate; and placing the dimethyl malate-leaf alcohol carbonate in a phosphate buffer solution, and treating with lipase to obtain the malic acid-leaf alcohol carbonate or malic acid monomethyl ester-leaf alcohol carbonate precursor fragrance perfume. The obtained leaf alcohol carbonate precursor fragrance spice is applied to heating cigarettes, and leaf alcohol can be released when the heated cigarettes are smoked, so that green fragrance is increased.

The invention provides a synthesis and purification process of high-purity chloroformate, and belongs to the technical field of chemical synthesis, and the synthesis and purification process comprises the following steps: S1, taking a mixed solution of bis (trichloromethyl) carbonate and an organic solvent as a base material, dropwise adding an alcohol compound under a temperature control condition, and carrying out phosgenation reaction to obtain a mixed reaction solution; s2, carrying out inert gas purging on the mixed reaction liquid obtained in the step S1 to remove free hydrogen chloride and phosgene so as to obtain a treated mixed liquid; s3, enabling the mixed solution treated in the step S2 to pass through an adsorption bed layer filled with an adsorption material, and carrying out deferrization and deacidification treatment; and S4, feeding the purified liquid obtained in the step S3 into a rectification unit, and separating the solvent from the product under a negative pressure condition to obtain high-purity chloroformate, the adsorption material comprises a zirconium-doped SBA-15 mesoporous molecular sieve skeleton, and an amidoxime group and a steric hindrance type tertiary amine group which are grafted on the surface of the skeleton. According to the process, the impurity content can be greatly reduced, and the product chromaticity index and the rectification yield can be improved.

The invention relates to oligomeric urea-amine molecules, preparation and application in carbon dioxide adsorption, and belongs to the technical field of high polymer materials. The preparation method comprises the following steps: firstly, reacting an amino-containing compound with p-nitrophenyl chloroformate to generate carbamate with a specific structure, and then reacting carbamate with hydrazine hydrate to combine amine groups in carbamate with hydrazine molecules in hydrazine hydrate to obtain oligomeric urea-amine molecules. The molecule has the characteristics of simple structure, excellent water solubility and high melting point, and can efficiently adsorb carbon dioxide; and after heating treatment at a relatively low temperature, desorption release of carbon dioxide can be realized, and regeneration of molecules can also be achieved.

The invention discloses a preparation method of tetradecyl chloroformate, which is characterized in that tetradecyl alcohol and phosgene are used as raw materials, tetradecyl chloroformate is used as a solvent, and tetradecyl chloroformate is prepared by reaction at the temperature of 0-30 DEG C. Compared with a conventional method, in the preparation method, by optimizing the solvent type and the reaction temperature condition, the reaction conversion rate and selectivity can be effectively improved, the technological process is simplified, high-yield and high-purity tetradecyl chloroformate can be rapidly and simply prepared, the product content is larger than or equal to 98%, the yield is larger than or equal to 98%, the product competitiveness can be improved, and the method is suitable for industrial production. The industrial application is convenient to realize and the industrial practicability is high.

The invention belongs to the technical field of compound synthesis, and particularly relates to a synthetic method of bifenazate, which comprises the following steps: (1) mixing isopropyl chloroformate and hydroxylamine hydrochloride in a solvent a, and reacting at a certain temperature under alkaline conditions to obtain an intermediate 1; (2) mixing the intermediate 1 and alkyl sulfonyl halide in a solvent b, and reacting at a certain temperature under an alkaline condition to obtain an intermediate 2; and (3) mixing the intermediate 2 and 3-amino-4-methoxybiphenyl in a solvent c, and reacting at a certain temperature under an alkaline condition to obtain the bifenazate. According to the novel synthesis method of the bifenazate, the bifenazate is synthesized by adopting novel raw materials and intermediates, and the method has the advantages that the raw materials are low in price, the synthesis route is short, the reaction conditions are mild, the yield is high, and industrial production is easy.