125 results about "Responsive polymer" patented technology

The invention belongs to the technical field of sewage treatment, and particularly relates to an intelligent response filter material, a preparation method thereof and a denitrification deep-bed filter tank. The intelligent response filter material is of a three-layer composite structure and sequentially comprises a carbon source inner core, a transition layer and a wrapping layer from the inner layer to the outer layer; the carbon source core comprises aquatic plant powder, aggregate and reinforced fibers, the transition layer adopts a hydrophilic modified porous carrier, and the wrapping layer adopts a pH responsive polymer. According to the invention, the intelligent response type filter material prepared from aquatic plant straws is adopted, and the pH response type envelope can automatically adjust the release rate of a carbon source according to the pH change caused by the denitrification process, so that intelligent on-demand supply of the carbon source is realized, and the denitrification efficiency and the utilization rate of the carbon source are greatly improved.

The present disclosure generally relates to carbon sequestration materials, and related systems, articles, and methods. In some embodiments, the carbon sequestration material comprises a gel. In some embodiments, the gel comprises a hydrophilic material, a thermo-responsive polymer, and a carbon dioxide capture medium. In accordance with some embodiments, the gel, when in the presence of water, is capable of sequestering and / or releasing gaseous carbon dioxide. In some embodiments, the gel has a relatively large sequestration capacity such that a relatively large amount of carbon dioxide per gram of gel can be sequestered by the gel. In some embodiments, the gel sequesters a surprisingly large amount of carbon dioxide when exposed to relatively humid conditions. In some embodiments, the gel releases an advantageous amount of gaseous carbon dioxide that was previously sequestered by the gel.

The invention relates to the technical field of antibacterial materials, and provides a light-enzyme-heat synergistic antibacterial nano composite material and a preparation method thereof.The preparation method comprises the steps that 1, a copper-based chalcogenide with a plasma resonance effect serves as a structural template, a transition metal oxide intermediate layer and a bismuth oxyhalide epitaxial layer are sequentially constructed on the surface of the copper-based chalcogenide with the plasma resonance effect through a step-by-step continuous solvothermal method, and the copper-based chalcogenide with the plasma resonance effect serves as the structural template; forming a core-shell heterojunction with Z-type energy band matching; (2) pre-assembling a natural enzyme and a monatomic nano-enzyme in a buffer system to form a composite catalytic unit with an electron transfer channel; and (3) by taking the core-shell heterojunction as a polymerization core, under the precise temperature control condition of 0-10 DEG C, initiating active free radical polymerization through an interface, constructing a thermal response polymer shell layer on the surface of the heterojunction, and encapsulating the composite catalytic unit in a functional microdomain of a polymer network in situ. The anti-bacterial fabric can achieve a better synergistic anti-bacterial effect.

The application discloses an oral nano-vaccine and a preparation method and application thereof, and relates to the technical field of immunology, and specifically discloses an oral nano-vaccine which comprises a nano-particle wrapped by a biomimetic bacterial membrane vesicle and an outer layer; the nano-particle comprises an antigen and a biodegradable polymer material; the biomimetic bacterial membrane vesicle comprises an ionizable flagellar lipoprotein, an immune adjuvant, a phospholipid, a sterol lipid and a polyethylene glycol lipid; and the outer layer is a pH-responsive polymer. The oral nano-vaccine provided by the application combines the immune activation advantages of natural bacterial membrane vesicles and the precise regulation characteristics of synthetic materials, significantly improves the transmembrane penetration capacity of the antigen in the intestinal epithelium and the overall activation effect of the mucosal immune system. The oral nano-vaccine provided by the application can protect the antigen and the immune adjuvant from degradation and realize precise release in the intestinal microenvironment; and the oral nano-vaccine significantly improves the bioavailability and safety of an oral tumor vaccine, and lays a key technical foundation for clinical transformation and large-scale production of the oral tumor vaccine.

The application discloses a catalyst for preparing methylaniline and a preparation method and application thereof, and belongs to the technical field of catalysts. The catalyst is prepared by modifying an activated carbon carrier with zirconium, cerium or nickel, treating the carrier with high-temperature nitrogen, loading active components Pd and pH-responsive polymers, solving the problems of low dispersion of the active components, easy poisoning and activity attenuation, and having good pH responsiveness and environmental adaptability. The preparation method optimizes a carrier modification process, adopts an impregnation method combined with timed stirring, controls reaction parameters, improves catalyst performance, realizes high selectivity and high yield of methylaniline, and has the advantages of high selectivity of the catalyst for methylaniline, inhibition of side reactions, adoption of a fixed bed reactor, simplification of operation, reduction of safety hazards, efficient reaction at a lower reaction temperature and pressure, and reduction of energy consumption and production cost.

The invention relates to the technical field of drug loading systems, and discloses a nanoparticle applied to photodynamic therapy and a preparation method thereof.The nanoparticle is of a core-shell-crown composite structure and sequentially comprises an inner core layer, an outer core layer, an inner shell layer and an outer shell layer from inside to outside, the inner core layer is composed of NaYF4 up-conversion nanoparticles, and the outer core layer is composed of NaYF4 up-conversion nanoparticles; the middle layer is a mesoporous Zr-MOF layer; the shell layer is a pH responsive polymer layer which is formed by connecting a polyethylene glycol-polycaprolactone block copolymer with folic acid through a hydrazone bond; the targeting canopy layer comprises double targeting ligands, and the double targeting ligands are respectively a bicyclo [6.1. 0] nonyne functionalized iRGD peptide and an azide functionalized anti-EGFR (epidermal growth factor receptor) nano antibody 7D12. The nanoparticles have the advantages of high stability, strong targeting property, high photosensitizer loading and the like, and can efficiently generate active oxygen.

Provided is a novel technique with which a temperature-responsive polymer, a hydrophilic polymer, and a hydrophobic polymer can be produced separately in a simple manner. The polymerizable composition contains the following monomers (A-1) and (B-1). (A-1) is a monomer represented by formula (1-1), and (B-1) is a monomer represented by formula (2-1) (in formula (1-1), R1 represents an alkanediyl group having 1-5 carbon atoms, and n represents an integer of 1-10). ) (In formula (2-1), R2 represents a linear alkanediyl group having 1-5 carbon atoms. ).

The present application relates to the technical field of soft coal seam drilling, and discloses an intelligent control drill rod and blowout hole device for soft coal seam drilling, which comprises a front-end sensing unit, a relay sensing unit, a hydraulic servo motor, a frequency converter, a shape memory alloy framework, a thermal-responsive polymer expansion gel layer and a control unit. The device can expand to 3 times the original diameter within 2 seconds through thermal triggering, forming a multi-stage labyrinth seal. The control unit is installed with an embedded AI chip to run an LSTM pressure time sequence prediction model, and combines temperature and vibration multi-source data fusion to judge the blowout risk level, solving the problems of lack of real-time gas pressure dynamic monitoring capability of traditional drill rods, reliance on artificial experience to judge blowout risk, and response lag. The single position pressure sensor is easily disturbed by local rock layer mutation, has a high false alarm rate, and cannot distinguish between normal pressure fluctuations and blowout precursors, so the device realizes early blowout warning and actively suppresses blowout accidents.

The invention relates to a preparation method of peppermint essence, which solves the problems of quick volatilization and poor durability of the traditional peppermint essence by optimizing the combination of essence components and a slow-release carrier by adopting a multi-layer microcapsule slow-release technology and a nanocapsule technology. According to the method, essence components such as menthol, menthone and leaf isovalerate are mixed with at least two layers of microcapsules, the outer layer microcapsules slowly release fragrance, the inner layer microcapsules quickly release fragrance, and it is ensured that the fragrance is kept for a long time in the using process. Meanwhile, the essence is uniformly dispersed in different carrier systems through ultrasonic-assisted emulsification by adopting a nanocapsule technology, so that the stability and dispersity of the essence are improved. In addition, the temperature-responsive and pH-responsive polymer materials are introduced, so that the release rate of the essence can be adjusted according to the external environment, and the adaptability of the essence is further enhanced.

A pressure sensing system (100) can include an ultrasound responsive polymer element which resonates at a resonance frequency when exposed to ultrasound waves (112) at an input frequency, at least one sensor (114) configured to directly or indirectly detect the resonance frequency, and at least one memory device (116) that has instruction that, when executed by at least one processor, cause the memory device (116) to correlate the resonance frequency detected to a pressure. Additionally, a method of detecting pressure can include identifying an area where pressure monitoring is desired, orienting an ultrasound responsive element (110) adjacent to that area, directing ultrasound waves (112) toward the ultrasound responsive element (110), detecting the resonance frequency produces by the ultrasound responsive element, and correlating that to a pressure.

This application provides a method for preparing pH-responsive polyamino acid drug-loaded nanoparticles based on sarcosine and their application. Sar-NNCA, L-lysine-NCA, and L-phenylalanine-NCA are dissolved in anhydrous DMF and polymerized under argon protection with a hexamethyldisilazine initiator to obtain a polyamino acid block copolymer Sar-NNCA. 80 -Lys(Cbz) n -Phe 10 The crude product was deprotected under HBr / acetic acid and loaded with DOX to obtain Sar. 80 -Lys n -Phe 10 -DOX. This application describes the preparation of a pH-responsive polymer nanoplatform, Sar, by encapsulating doxorubicin in polysarcosine-polylysine-polyphenylalanine nanoparticles via Schiff base bonds. 80 -Lys n -Phe 10 -DOX is used for tumor treatment. These polyamino acid nanoparticles are spherical with an average particle size of approximately 200 nanometers, exhibiting pH-responsive properties, excellent cellular uptake capacity, and anti-tumor effects. In vitro experiments show that Sar... 80 -Lys n -Phe 10 The carrier material exhibits excellent biocompatibility. The newly synthesized Sar... 80 -Lys n -Phe 10 -DOX nanomicelles show promise as a drug delivery system for cancer treatment.

The invention discloses a bio-responsive high polymer material and application thereof, and belongs to the technical field of biomedical materials. The bio-responsive high-molecular material provided by the invention contains polymers shown as formulas i to viii. Wherein the polymers of the formulas i to viii have excellent fluorescence performance, aggregation-induced fluorescence enhancement performance, multicolor luminescence performance and biological response capability based on a redox reversible switch, and can be applied to sensing, counterfeiting prevention, metal ion detection, multicolor imaging of in-vivo and in-vitro cells and / or tissues and quantitative detection of in-vivo and in-vitro oxidized and / or reducing substances; active oxygen in in-vivo and in-vitro tissues and cells can be removed to achieve long-acting anti-inflammatory and anti-oxidation effects, and the compound can be used for treatment of oxidative stress related diseases and visual monitoring of the treatment process; the biological activity of enhancing tissue retention, stimulating collagen generation, repairing tissue and resisting oxidation and aging of the tissue is achieved, and the effect of filling and repairing in-vivo cells and tissue can be effectively improved; the compound also has the capability of being chelated with metal ions to form a high-molecular metal complex, and can be used for resisting tumors, resisting bacteria, filling and repairing tissues, promoting collagen generation and the like.

Described herein are therapeutic pH-responsive micelle compositions comprising block copolymers and biological therapeutic agents useful in the treatment of cancer, methods for making such micelles, and intermediate compositions useful for making such micelles.

This invention relates to the field of biomedicine and discloses a composition for treating non-small cell lung cancer metastasis that targets replication stress vulnerability and its application. The composition includes a dual-responsive polymer prodrug, which consists of a block copolymer backbone, a matrix metalloproteinase cleavage peptide sequence coupled to the hydrophilic end, and an active molecular group coupled to the hydrophobic end based on an asymmetric grafting structure. The active molecular group comprises a replication stress inducer and an ATR kinase inhibitor. This invention maintains the amorphous phase of the micelle core through the asymmetric grafting structure, eliminating the permeation barrier caused by spontaneous crystallization of components. This amorphous core provides a proton permeation channel, ensuring the synchronous in-situ release of multiple target drugs, thereby blocking the DNA replication fork repair pathway and inducing mitotic catastrophe, maintaining the spatiotemporal overlap of multiple drug interventions in the pathological target area, and avoiding the risk of drug resistance.

The invention belongs to the technical field of concrete repairing, and particularly relates to an interface bonding material for concrete repairing and a preparation method and application thereof. The interface bonding material for concrete repair comprises the following components in parts by mass: a component A: 5-15 parts of functionalized graphene, 8-12 parts of a humidity response polymer, 4-8 parts of a temperature response polymer, 3-5 parts of a pH response polymer, 30-35 parts of an epoxy resin matrix, 10-15 parts of modified acrylic resin, 2-3 parts of a coupling agent and 3-5 parts of a nano reinforcing agent; the component B is a modified amine curing agent; the functionalized graphene is graphene of which the surface contains at least one of carboxyl, amino and hydroxyl. The interface binding material for concrete repair is good in environment adaptability and good in binding and anti-permeability performance.

The application discloses a kind of super-hydrophobic material and its preparation method and application, belong to functional material field.The application first uses bis (3-amino propyl) end-capped poly (dimethylsiloxane), diisocyanate compound, dissolves in organic solvent, carries out prepolymerization, then slowly adds the polyamino compound of tertiary amino group, carries out addition polymerization reaction, obtains pH response type polymer solution;Afterwards, hydrophobic nanoparticles are added in pH response type polymer solution, and mixed solution is obtained;Finally, the mixed solution is used to treat cellulose fiber material, and a pH-responsive and self-repairing super-hydrophobic material is obtained.The application utilizes the protonation and deprotonation of pH-responsive polymer in different pH environments to provide super-hydrophobicity and underwater super-oleophobicity for the surface of super-hydrophobic material, and at the same time, the pH-responsive super-hydrophobic material has the properties of organic solvent resistance, abrasion resistance, ultraviolet resistance, heat resistance, etc.

The invention discloses a cellulose-based light-emitting polymer and a preparation method and application thereof, the cellulose-based light-emitting polymer has a structure as shown in a formula (I), and the cellulose-based light-emitting polymer is prepared by carrying out click polymerization reaction on an organic light-emitting group with AIE characteristics and ethyl cellulose in an organic solvent under the catalysis of an organic base. The obtained polymer has both high transparency and high ultraviolet impedance effect, also has fluorescence characteristic, and realizes ultraviolet shielding and indication functions for ultraviolet sensitive materials. Along with the increase of the grafting rate, the fluorescence color can be regulated from blue-green to orange red, the grafting-rate-dependent multi-color luminescence characteristic is presented, and the method can be applied to the field of multi-color fluorescence two-dimensional codes. The acid-responsive polymer is developed through secondary grafting, can realize fluorescence discoloration under acidic stimulation, and can be used for constructing a dynamic multicolor encoding device with high data storage density and enhanced encryption capability. The invention provides an innovative method for developing reversible and multifunctional fluorescent cellulose materials.

The invention provides a preparation method of a controllable slow-release urea fertilizer based on coal-based quantum carbon dot coating, and relates to the technical field of fertilizer preparation, the preparation method comprises the following steps: taking urea, a coal-based quantum carbon dot dispersion liquid, a natural high-molecular polymer binder, trace elements and a response type polymer as raw materials, and carrying out raw material pretreatment, urea particle coating treatment and post-treatment; the response type polymer introduced into the coating material and the coal-based quantum carbon dots can form a synergistic controlled release system, hydroxyl and carboxyl on the surfaces of the coal-based quantum carbon dots and amino and ether bonds (-O-) on molecular chains of the response type polymer can form hydrogen bonds and coordinate bonds, and a stable composite coating layer network structure is constructed; when the soil environment changes, the acting force between the functional groups reversibly changes, the change amplitude of the porosity of the coating layer is further regulated and controlled, the regulation and control precision of the nutrient release rate is improved by 15%-20%, and meanwhile, the problem of nutrient burst release caused by local damage of the coating layer can be avoided.

A biosensor for monitoring surface binding events is disclosed. The biosensor comprises an array of nanoparticles and an analyte responsive polymer. The array of nanoparticles includes a plurality of nanoparticles distributed across the nanoparticle array. The analyte responsive polymer includes a recognition element at a first end of the polymer and a terminus at a second end of the polymer distal from the recognition element, the terminus end being conjugated to the nanoparticles in the array. When the recognition element reacts with an analyte, the analyte responsive polymer creates an electrochemical signal at the surface of the nanoparticle array which can be measured to monitor surface events of the analyte responsive polymer.

The invention discloses a biological material for vascular intervention and a preparation method thereof, and relates to the technical field of biological materials.The biological material comprises a stent base body and a functional coating coated on the surface of the stent base body, and the stent base body is made of a degradable metal material; the functional coating is composed of a bioactive substance, a drug sustained-release carrier, a nanoparticle enhancer and an intelligent responsive polymer. The biological material and the preparation method have the remarkable advantages that the micro-nano structure of the scaffold matrix promotes cell adhesion and proliferation, and the mechanical property is good; the functional coating realizes controllable release of the medicine and enhances the stability; the preparation process innovation ensures high quality of the material; a sensor and a protective film are integrated, so that the safety and functionality are improved, and the clinical application prospect is wide.

The invention belongs to the technical field of concrete structure protection and repair, and particularly relates to a graphene-based anti-permeation interface treating agent as well as a preparation method and a construction method thereof. The graphene-based anti-permeation interface treating agent is prepared from a component A and a component B. The component A is prepared from, by mass, 30-60 parts of functionalized graphene oxide dispersion liquid, 15-25 parts of reduced graphene dispersion liquid, 30-60 parts of nano silicon dioxide, 120-200 parts of waterborne epoxy resin emulsion, 3-8 parts of a dispersing agent, 1-2 parts of a defoaming agent and deionized water. The component B is prepared from 50 to 100 parts of functionalized graphene oxide dispersion liquid, 60 to 100 parts of nano silicon dioxide, 40 to 80 parts of nano filler, 30 to 65 parts of response type polymer, 100 to 180 parts of waterborne epoxy emulsion, 4 to 10 parts of dispersing agent and deionized water. The graphene-based anti-permeation interface treating agent disclosed by the invention is good in water resistance, and is beneficial to improving the interface bonding property with concrete.

The application provides a contrast medium catheter with photo-controllable deformation and application thereof. The contrast medium catheter with photo-controllable deformation comprises a catheter seat, a tube body, a transition section and a photo-controllable deformation head; one end of the tube body is connected to the catheter seat, the inner cavity of the tube body is communicated with the spherical inner cavity of the catheter seat, the other end of the tube body is connected to the transition section, the other end of the transition section is connected to the photo-controllable deformation head, and the photo-controllable deformation head is prepared from raw materials including photo-responsive polymer materials and near-infrared light conversion materials. The contrast medium catheter can realize the change of the shape of the head of the contrast medium catheter, deflect a certain angle, and then more accurately and quickly enter the correct blood vessel branch through the irradiation of the near-infrared light outside the body.

The invention discloses a full-degradable intragastric balloon and a preparation method thereof, and relates to the technical field of medical instruments. The intragastric balloon is of a double-layer composite structure, the outer layer of the balloon is an alkali response gel film, and the inner layer of the balloon is an acid response polymer film; the alkali response gel film is a PVA-boric acid gel film, and the acid response polymer film is polymethacrylate resin. The dual pH response mechanism ensures that the damaged balloon is not detained in the intestinal tract for a long time, and the risk of causing intestinal obstruction is reduced. Therefore, the safety of the intragastric balloon is improved, and the active safety design concept that the function can be maintained and the failure can be degraded is achieved.

The invention belongs to the technical field of energy materials, and particularly relates to a metallized plastic composite current collector and a preparation method and application thereof. The metallized plastic composite current collector is prepared by selecting a first polymer with a melting point of 60-100 DEG C and a conductive filler to form a PTC compound, then blending the PTC compound with a second polymer with a melting point of 120-200 DEG C to form a thermal response polymer layer, and forming a metal layer on the surface of the thermal response polymer layer. The thermal response temperature range of the metallized plastic composite current collector is reduced to 60-100 DEG C, internal electrochemical reaction of the battery is cut off at a proper temperature, internal components and structure degradation of the battery is avoided, the battery is better protected, meanwhile, the metallized plastic composite current collector has good mechanical performance and interface stability in the processing and thermal response process, and the service life of the battery is prolonged. And the structure of the composite current collector is not damaged. Rapid and reversible thermal turn-off at a low temperature is realized, and the structural integrity at a high temperature is ensured at the same time.

The application discloses a kind of ion response type high polymer film wrapped active ingredient spinning solution and its preparation method and application, the spinning solution includes the following components: polymer matrix, antioxidant and solvent;The polymer matrix includes sodium alginate and polyvinyl alcohol;The mass ratio of sodium alginate and polyvinyl alcohol is 1: (2.5-5). Sodium alginate in spinning solution has good ion response and biocompatibility, under the action of Ca 2+ , Al 3+ And other metal ions can be quickly crosslinked to form gel film, realize the wrapping of active ingredient;Polyvinyl alcohol has excellent spinning performance and mechanical properties, and can improve the stability of spinning solution and the mechanical strength of fiber by compounding with sodium alginate, avoid the problems such as broken wire and needle blockage in spinning process, suitable for electrospinning process application.

CO2-responsive polymer designed to be activated using CO2-sensitive microcapsules for sealing flow paths to improve the integrity of wellbores.

The invention relates to a gastric mucosa targeted repair type amino acid preparation as well as a preparation method and application thereof, and the preparation raw materials comprise the following components in parts by weight: 10-30 parts of gelatin, 5-15 parts of L-glutamine, 4-8 parts of an acidity regulator, 0.5-2.5 parts of MMP-9 specific lysis polypeptide, 0.4-0.6 part of gastric mucosa lesion targeted peptide and 3-7 parts of a pH responsive polymer. The pH response type polymer comprises ethyl cellulose and a methylation modified poly (acrylic acid-methyl methacrylate) copolymer. According to the amino acid preparation prepared by compounding the components, the targeted repair performance of the amino acid preparation on the gastric mucosal lesion part can be efficiently improved.

This invention belongs to the field of nanomedicine technology, specifically relating to a pH / hypoxia dual-responsive polymer, nanomicelles, their preparation method, and applications. The pH / hypoxia dual-responsive polymer is a hydroxyethyl deacetylated chitosan modified with p-nitrobenzyl chloroformate and cinnamaldehyde. Ropivacaine is loaded onto it and prepared into nanomicelles for use as a drug delivery system after tumor surgery. Due to its acid sensitivity and hypoxia response, it can intelligently identify the tumor microenvironment, achieving precise drug delivery.

The invention relates to the technical field of advanced chemical new materials, and discloses a preparation method of high-adhesion carboxylic butadiene-styrene latex, which comprises the following steps: introducing a novel amphiphilic polymer emulsifier carboxylated styrene-maleic anhydride copolymer, finely regulating the distribution of monomers on an oil-water interface in an emulsion polymerization process, and preparing the high-adhesion carboxylic butadiene-styrene latex. Therefore, uniform copolymerization of the monomer is realized. According to the invention, a multifunctional and responsive polymer emulsifier is constructed, so that the problem of monomer compatibility existing in traditional emulsion polymerization for a long time is successfully solved, and precise regulation and control between a microstructure and macroscopic properties of latex are realized. The obtained carboxylic butadiene-styrene latex with high binding power has excellent stability and reliability, provides a solution for the fields of high-performance building materials, protective coatings, adhesives and the like, and shows technical progress and excellent application prospects.

This invention belongs to the field of HVAC systems and discloses a multi-stage air water collection system and its operation method based on thermally responsive polymers. The system includes a first thermally responsive polymer module, a second thermally responsive polymer module, a pre-cooled water collector, a first fan, a heater, a post-condensate water collector, a second fan, a water collection unit, a first solenoid valve, a second solenoid valve, a third solenoid valve, a fourth solenoid valve, a fifth solenoid valve, a sixth solenoid valve, a seventh solenoid valve, an eighth solenoid valve, a first dew point temperature sensor, and a second dew point temperature sensor. The system operates by switching valves and using dual-stage operation of the post-condensate water collector and heater, matching the multi-stage desorption characteristics of the thermally responsive polymer, thereby achieving multi-device, multi-stage atmospheric water collection. By matching this system and the corresponding operation method, sufficient moisture in the air can be collected, while ensuring that each stage of the system operates in a minimum energy consumption mode, achieving low-energy air water collection.