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98results about How to "Good mechanical support" patented technology

Preparation method of high-strength ion-responsive lubricating hydrogel

InactiveCN108341973AGood mechanical supportTo achieve the purpose of reversible regulation of lubricationSkin complexionPhysical chemistry
The invention relates to a preparation method of high-strength ion-responsive lubricating hydrogel, belonging to the technical field of ion response. The preparation method combines a high-strength hydrogel material with a synergistic design system of ion-responsive supramolecular hydrogel, and realizes the regulation and control of the surface lubrication of the hydrogel material by regulating the bulk phase of the hydrogel material as well as surface ion species and charged state. On the one hand, the high-strength hydrogel can give good mechanical support to cartilage; on the other hand, the ion-responsive supramolecular hydrogel can undergo gel-sol conversion under the action of external ions, and the factors such as ion species and concentration of the environment in which the hydrogel is located can be further controlled according to complexion situations of different ions by an ion-responsive polymer, so that the purpose of reversible regulation of hydrogel surface lubrication is achieved, and the hydrogel is enabled to automatically adjust the strength and the surface lubrication performance. The high-strength ion-responsive lubricating hydrogel greatly enhances the stability and environmental adaptability of bionic cartilage, thus having a very good medical prospect.
Owner:JILIN UNIV

Fixing device for fractures of anterior column, posterior column and square area of acetabulum and method

InactiveCN104644255ANot easily deformedReduce traumatic arthritisBone platesSteel platesFossa iliaca
The invention discloses a fixing device for fractures of an anterior column, a posterior column and a square area of an acetabulum and a use method thereof. The fixing device comprises a trapezoid main board and a pubic auxiliary board; the integral shape of the trapezoid main board and the pubic auxiliary board is matched with anatomical structures of the insides of the anterior column and the posterior column of the acetabulum and the square area of the acetabulum; an arcus marginalis steel plate positioned at an ilium arcus marginalis is arranged at the upper part of the trapezoid main board; a posterior column steel plate is arranged at one side edge of the trapezoid main board; after being crossed, the posterior column steel plate and the arcus marginalis steel plate are bent and extend towards the fossa iliaca to form a posterior column side wall; an ischium steel plate is arranged at the lower part of the trapezoid main board; a square area baffle is arranged among the arcus marginalis steel plate, the posterior column steel plate and the ischium steel plate; the pubic auxiliary board is matched with an anatomical structure of the inside of the superior pubic ramus, is bent near a pubic tubercle and extends towards the upper surface of the superior pubic ramus to form a pubic side wall; the trapezoid main board and the pubic auxiliary board are provided with a plurality of screw holes. By using the fixing device, the acetabulum fractures can be stably reduced and fixed and quality of fracture reduction and internal fixation is improved.
Owner:郭晓东

Preparation method of microchannel heat sink for high-heat flux heat dissipation

The invention relates to a preparation method of a microchannel heat sink for high-heat flux heat dissipation. The method includes the following steps that: a) materials are selected; b) a microchannel is made inside a plate; c) three-dimensional microchannel deformation-free modeling is performed; d ) and a metal frame, a ceramic frame, an outer lead, an IC device, a sensor and a heater are integrated on an active microchannel heat sink, so that system miniaturization can be realized, mechanical support and environmental protection are provided for a chip and an internal circuit, and an input and output function is realized for the chip and the internal circuit. The thermal expansion coefficient of the product is adjustable; and heat generated by devices or a system can be taken away from the heat sink through a high-thermal conductivity medium, the temperature of the surface of the heat sink can be decreased as much as possible and remain constant. The microchannel heat sink has the advantages of small size, large heat dissipation area, good solderability and high stability, and can meet the requirement of high-power density heat dissipation, and can be in sealed connection with other components or parts.
Owner:NO 55 INST CHINA ELECTRONIC SCI & TECHNOLOGYGROUP CO LTD

Active-oxygen-responsive degradable polyurethane heart patch for myocardial infarction repair and preparation method thereof

The invention discloses an active-oxygen-responsive degradable polyurethane heart patch for myocardial infarction repair and a preparation method thereof. The heart patch comprises a cast membrane, an electrospun fibrous membrane and a porous membrane, and polyurethane is active-oxygen-responsive degradable polyurethane containing thioketal bonds. The invention also provides a method for preparing the heart patch. The preparation method is simple and is convenient to operate, active-oxygen polyurethane films with different pore sizes and porosities can be prepared as required, and the active-oxygen polyurethane films have good mechanical properties, oxidation resistance, degradability and biocompatibility. Under the condition that functional cells or factors are not added into the polyurethane patch, cardiac functions can be effectively recovered after myocardial infarction, and the left ventricle remodeling and fibrosis degree after myocardial infarction can be inhibited; and after the cells or active factors are added, the treatment effect can be further improved. The active-oxygen-responsive degradable elastic polyurethane heart patch disclosed by the invention is simple in preparation method and has a good application prospect.
Owner:ZHEJIANG UNIV

Nanofiltration membrane, preparation method and application thereof

The invention discloses a nanofiltration membrane, a preparation method and application thereof. The nanofiltration membrane comprises a support bottom membrane and an active separation layer arrangedon the support bottom membrane, wherein the active separation layer has an interpenetrating network structure, and the interpenetrating network structure is mainly formed by interpenetrating polyamide formed by an interfacial polycondensation reaction of a polyethyleneimine monomer and an acyl chloride monomer with ultrafine nanofibers. The preparation method comprises the following steps: arranging an ultrafine nano-fiber layer on a micro-filtration membrane to prepare an ultrafine nano-fiber / micro-filtration membrane composite substrate; and carrying out an interfacial polycondensation reaction on a polyethyleneimine monomer and an acyl chloride monomer on the surface of the superfine nanofiber / micro-filtration membrane composite substrate, and carrying out heat treatment to obtain thenano-filtration membrane. The preparation method of the nanofiltration membrane is simple, and the obtained nanofiltration membrane has high flux and high salt rejection performance, so that the desalination energy consumption cost is reduced, and the nanofiltration membrane has a wide application prospect in the aspects of seawater desalination pretreatment, water softening and the like.
Owner:SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI

Shear force-responsive supramolecular bionic articular cartilage material with dynamic lubrication and self-repairing ability and preparation method thereof

The invention relates to a shear force-responsive supramolecular bionic articular cartilage material with dynamic lubrication and self-repairing ability and a preparation method thereof, and belongs to the technical fields of bionic self-repairing and lubricating articular cartilage materials and preparation thereof. Inspired by articular cartilage, a covalently crosslinked high-strength hydrogelnetwork, a shear force-responsive supramolecular network and an intrinsic self-repairing structural motif are organically combined to provide an intelligent hydrogel material having a function of bionic articular cartilage activity. The intelligent hydrogel material has good mechanical properties and a shear self-lubricating function; more importantly, through the interaction between a shear force-responsive exudation lubricating layer and a self-repairing motif, the dynamic exudation lubrication mechanism is simulated while realizing the double repair of a three-dimensional network structureand the shear force-responsive self-lubricating function after the material is worn. The design concept can be applied to the preparation of new artificial articular cartilage or self-repairing lubrication devices, and has broad application prospects.
Owner:JILIN UNIV

Novel dual-layer nerve conduit and preparation method thereof

The invention provides a novel dual-layer nerve conduit. The novel dual-layer nerve conduit consists of an electrospin decellularization pig nerve substrate conduit layer, and a PLCL layer arranged onthe outer layer of the electrospin decellularization pig nerve substrate conduit layer. Besides, the invention provides a preparation method of the novel dual-layer nerve conduit. The preparation method comprises the following steps of (1) pretreating pig nerves; (2) performing decellularization on the pretreated pig nerves; (3) performing crushing and drying treatment on nerves after being subjected to decellularization; (4) performing electrostatic spinning on the dual-layer nerve conduit layer; and (5) performing post-treatment on the dual-layer nerve conduit layer. The novel dual-layer nerve conduit prepared by the method disclosed by the invention has good biocompatibility and favorable machinery support; an inner-layer decellularization matrix contains various kinds of functional proteins, including collagen, proteoglycan, glycosaminoglycans and nerve growth factors, proliferation, migration and axon growth of schwann cells can be promoted, and the outer-layer PLCL can also effectively prevent hyperplasia of fibrous connective tissue and invasion of surrounding tissue.
Owner:中国医科大学
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