227 results about "Nucleophilic addition" patented technology

In organic chemistry, a nucleophilic addition reaction is an addition reaction where a chemical compound with an electron-deficient or electrophilic double or triple bond, a π bond, reacts with electron-rich reactant, termed a nucleophile, with disappearance of the double bond and creation of two new single, or σ, bonds. The reactions are involved in the biological synthesis of compounds in the metabolism of every living organism, and are used by chemists in academia and industries such as pharmaceuticals to prepare most new complex organic chemicals, and so are central to organic chemistry. Addition reactions require the presence of groups with multiple bonds in the electrophile(due to the fact that double bonds and even triple bonds can both lack electron rich sources): carbon–heteroatom multiple bonds as in carbonyls, imines, and nitriles, or carbon–carbon double or triple bonds. The lack of electron rich sources is due to the fact that these bonds are partially empty, even though they remain connected, since the region occupying the orbital is essentially dead. This electrophilic behavior is defined as empty space since everything inside is basically without any source of electricity except from outside the bond, since bonds tend to want to attract more to themselves(whether this be electric or non-electric can differ in most situations). The addition of the nucleophile means the continuous addition of a negative charge throughout the reaction, unless an electrophile also makes itself present to form a complete structure with no charge at all. The negative charge being continuous throughout the reaction until the formation of an intermediate, bearing the charge, thus is the addition reaction we have before us. Once this meets an electrophile, then the intermediate formed with the negative charge can thus be neutralized to form a complete structure via a type of bond.