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310results about How to "Low market price" patented technology

Preparation method of metformin hydrochloride

The invention discloses a preparation method of metformin hydrochloride. The method comprises: taking 40% dimethylamine as a starting material, which is subjected to a salification reaction with hydrochloric acid salt forming reaction of dimethylamine hydrochloride, subjecting the dimethylamine hydrochloride and dicyandiamide to an addition reaction in solvent N, N-dimethylformamide so as to generate a metformin hydrochloride crude product, then conducting refining, thus obtaining metformin hydrochloride. The solvent of the invention has viscosity insusceptible to temperature, and is easy to be separated from the product. Besides, the solvent can dissolve the reactant dicyandiamide, and even if dicyandiamide is not fully reacted, it cannot be separated out during separation of the product and the solvent, so that the production operation can be easier, and the purity of the final product can be very high. The method of the invention has the advantages of simple and easy production operation, high raw materialutilization rate, and cheap as well as easily available solvent, the market price of which is 2-3 times lower than prices of solvents in prior, and the synthesis cost is reduced by about 30%, so that the preparation method of the invention is very suitable for industrial production of metformin hydrochloride.
Owner:赤峰万泽药业股份有限公司

Holmium-contained Nd-Fe-B rare earth permanent magnetic material and manufacturing method thereof

InactiveCN101404196AIncreased coercive force HcjReduce manufacturing costMagnetic materialsRare-earth elementHolmium
The invention provides an Nd-Fe-B rare earth permanent magnet material containing Ho and a preparation method thereof; the composition of the Nd-Fe-B rare earth permanent magnet material containing Ho comprises Re Alpha Ho Beta B Gama MxNyFe 1-Alpha-Beta-Gama-x-y; wherein, Re is rare earth element and comprises Nd or Nd as well as one or more elements out of La, Ce, Pr, Pm, Sm, Eu, Tb, Dy, Ho, Er, Tm, Yb, Lu, Y and Sc; M is addition element and comprises Co and Cu; N is addition element and comprises one or more elements out of Al, Ga, Nb, Zr, Ti and Sn; Alpha, Beta, Gama, x and y are respectively weight percentage of all elements; Fe is iron and unavoidable impurities; wherein, Alpha is not more than 35% and not less than 29%; Beta is not less than 0.05% and not more than 0.5%; Gama is not more than 1.20% and not less than 0.95%; x is not more than 10% and is not less than 0; y is not more than 1.50% and not less than 0. The preparation method adopts the continuous procedures such as smelting, casting, crushing, forming and sintering to prepare a magnet. The Hcj of the Nd-Fe-B rare earth permanent magnet material is improved and the production cost thereof is reduced after Ho is added in the Nd-Fe-B rare earth permanent magnet material.
Owner:ZHEJIANG SHENGHUA MAGNETIC MATERIALS

Method for preparing enhanced heat-transfer and scale prevention coating of micron/nanometer titanium dioxide on stainless steel substrate

The invention discloses a method for preparing an enhanced heat-transfer and scale prevention coating of micron/nanometer titanium dioxide on a stainless steel substrate, comprising the following steps of: (a) pre-treating the stainless steel substrate; (b) preparing ammonium fluorotitanate and boric acid into uniform solutions, and mixing the two solutions uniformly; (c) placing the prepared mixed solution in a water bath and controlling the temperature thereof at 20-80 DEG C, suspending the stainless steel substrate perpendicularly in the mixed solution and starting to deposit to prepare the substrate coated with TiO2 thin film after the temperature of the mixed solution is stable; (d) after deposition, picking the substrate out and washing the surface of the substrate with distilled water; and (e) drying the substrate naturally, then placing the substrate in a resistance furnace to heat to obtain the micron/nanometer TiO2 surface coating. The coating prepared by adopting the method is compact and uniform in appearance and the Ra value of the sintered surface coating is substantially equal to that of the polished surface coating. The coating is high-temperature resistant and is combined with the substrate more firmly.
Owner:TIANJIN UNIV

Method for preparation of m-aminobenzenesulfonic acid by catalytic hydrogenation

Belonging to the field of fine chemical industry, the invention in particular relates to a method for preparation of m-aminobenzenesulfonic acid by catalytic hydrogenation. The method includes: taking sodium m-nitrobenzene sulfonate as the raw material, adding water for dissolving, boiling the mixture by activated carbon, conducting hot filtration, adjusting the pH value of the filtrate to 7.5-8.5 by a sodium hydroxide aqueous solution, employing Pt-Ru/C as a catalyst to perform hydrogenation reduction for preparation of m-aminobenzenesulfonic acid, ending the hydrogenation reduction reaction when the hydrogen pressure no longer changes, filtering out the Pt-Ru/C catalyst at the end of the reaction, firstly washing the catalyst by ethanol, then carrying out washing recycling, with the recycled catalyst being able to be applied over 50 times and still having a conversion rate and selectivity up to 99%; and subjecting the obtained filtrate to acid precipitation to pH of 2, thus obtaining a white crystal, i.e. the target product m-aminobenzenesulfonic acid. The method provided by the invention lowers the catalyst cost, improves the utilization rate of equipment, and also overcomes the problems of pollution and energy consumption in the regeneration process of the catalyst.
Owner:中国中化股份有限公司 +1

Immobilized composite unhairing enzyme with leather-making secondary waste as carrier and preparation method thereof

InactiveCN103525954AReduce the degree of actionMinimize or avoid damagePre-tanning chemical treatmentFiberNeutral protease
The invention discloses a preparation method of an immobilized composite unhairing enzyme with leather-making secondary waste as a carrier. The method is characterized by: firstly soaking the leather-making secondary waste in deionized water at room temperature, then reacting the leather-making secondary waste with glutaraldehyde, conducting filtration and washing off the residual glutaraldehyde on the leather-making secondary waste by deionized water; reacting the glutaraldehyde treated carrier with the composite unhairing enzyme, performing filtration and washing off the residual composite enzyme on the carrier, thus obtaining the immobilized composite unhairing enzyme with leather-making secondary waste as the carrier. Specifically, every 100 parts of the composite unhairing enzyme comprise 55-80 parts of neutral protease, 10-25 parts of alpha amylase and 5-15 parts of pancreatin. The immobilized composite unhairing enzyme prepared by the method involved in the invention has a high immobilized enzyme amount and high enzyme activity yield, and has good stability and reusability. The immobilized composite unhairing enzyme can be used for raw hide unhairing and collagen fiber dispersion, the production conditions are mild, high controllability can be achieved on a hide collagen hydrolysis process and the separation and loose degree of collagen fibers, and also the product quality fluctuation can be avoided in production.
Owner:SICHUAN UNIV

Random color dot matrix label anti-counterfeiting system

The invention belongs to the anti-counterfeiting technology field and discloses a random color dot matrix label anti-counterfeiting system. The system comprises anti-counterfeiting code dot matrix images and a composite image, wherein software generates the anti-counterfeiting code dot matrix images with a variable quantity, size and position, and multiple random colors around a two-dimensional code; and the software guarantees the reliability of code scanning, and simultaneously, the two-dimensional code is divided into four color areas, the colors of the four color areas are changed randomly, the anti-counterfeiting code dot matrix images and an original anti-counterfeiting base plate are synthesized so as to generate an image format used for a printing machine and send to the printing machine for printing, an independent label can be printed or the image can be directly printed to a product package, and simultaneously, the complete image is stored in a system database for backup sothat query and comparison can be performed. A simple and operable mode with low cost is adopted, and the counterfeiting cost of a counterfeiting enterprise is increased so as to protect the brand andthe fame of an enterprise. The products of the enterprise are reliable and competitive in a marketplace.
Owner:CHONGQING YANSHEN TECH DEV CO LTD

Magneto-rheological clutch, brake and variable speed control drive assembly device

The invention belongs to the technical field of drive assembly devices, in particular to a magneto-rheological clutch, brake and variable speed control drive assembly device, which is formed by assembling a coupling, an upper shell, a lower shell, a clutch coil, a clutch shell, a brake coil, a brake shell, a clutch holder shaft, a clutch disc shaft, a clutch bearing, a brake pad bracket, a reversing bearing, a reversing gear, a reversing shaft and a power gear; when a vehicle starts, the coupling inputs power to the clutch disc shaft; when the vehicle runs, current is input into the clutch coil, a magneto-rheological material is subjected to phase change, and the power is transmitted to the reversing shaft from the clutch disc shaft through the power gear and the reversing gear; and when the vehicle is braked, the current input into the clutch coil and the brake coil is cut off, the magneto-rheological material is subjected to phase change, and the brake pad bracket and the reversing shaft are in a brake locking state. The device solves technical problems to achieve light-weight product, simple structure, material reduction and intelligent control, and powerful support is provided for promoting new materials, new technologies, new processes and technical upgrade of products.
Owner:山东格新精工有限公司
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