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183 results about "Cardiorespiratory arrest" patented technology

Cardiac arrest is a sudden loss of blood flow resulting from the failure of the heart to effectively pump.

Packaging structure of half-bridge power module, use of packaging structure of half-bridge power module, and manufacturing method for packaging structure of half-bridge power module

Disclosed in the present invention is a packaging structure of a half-bridge power module. The packaging structure comprises an insulating and thermal conductive plate, a multi-layer circuit board, a plastic package body and a bridge arm switch. Further disclosed in the present invention is the use of a packaging structure of a half-bridge power module in an OBC power source converter, a DCDC isolated converter, a non-isolated power source converter, a cardiac arrest awakening apparatus, and a circuit module formed by means of combining multiple half bridges such as ANPC, TNPC and Heric. Further disclosed in the present invention is a manufacturing method for a packaging structure of a half-bridge power module. The method comprises: performing assembling; providing an overflow region; and synchronously performing filling and grinding to remove the overflow region. In the present invention, a minimum size and a low impedance are achieved by means of DBC, flexible pin leading-out and welding are realized by means of a PCB, the reliability, safety and heat dissipation of modules are supported by means of a plastic packaging body, and the extension of a temperature monitoring unit and a decoupling capacitor is supported.
Owner:SHANGHAI METAPWR ELECTRONICS CO LTD

Fuzzy logic method-based cardiac arrest risk level prediction method and system

The invention relates to a cardiac arrest risk grade prediction method and system based on a fuzzy logic method, and the method comprises the steps: obtaining real-time vital sign data of a patient, the real-time vital sign data comprising at least one of heart rate, blood pressure, oxyhemoglobin saturation and respiratory rate; on the basis of the real-time vital sign data, feature selection and importance evaluation processing are carried out through a machine learning algorithm, and target features most related to the sudden cardiac arrest risk are obtained; performing fuzzification processing based on fuzzy C-means clustering on the basis of the target features so as to convert the accurate numerical data into a fuzzy set; according to a fuzzy logic principle, in combination with a case-based reasoning method, performing matching calculation on the fuzzy set and known sudden cardiac arrest case characteristics to obtain a sudden cardiac arrest risk level; based on the cardiac arrest risk level, risk level evaluation is carried out, and a corresponding early warning mechanism is triggered. The implementation of the method can improve the accuracy and comprehensiveness of prediction.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

AED intelligent first-aid management system based on Internet of Things

The invention discloses an AED intelligent first-aid management system based on the Internet of Things, and relates to the technical field of first-aid management, and the system comprises a data collection and transmission module, a first-aid decision support module, a resource scheduling and cooperation module, and a first-aid training and evaluation module. The first-aid decision support module processes acquired data by using big data analysis and an artificial intelligence algorithm, quickly judges the type and severity of cardiac arrest, generates a personalized first-aid scheme and pushes the personalized first-aid scheme to first-aid personnel equipment, and the resource scheduling and collaboration module tracks AED equipment and personnel information in real time, plans and deploys a path and an attendance route in combination with road conditions, and sends the path to the first-aid personnel equipment. The system is connected with a hospital system to realize efficient cooperation of first aid; through deep fusion of the Internet of Things technology, big data and artificial intelligence, an efficient and intelligent AED first-aid management system is constructed, the first-aid response speed and success rate are remarkably improved, and precious treatment time is won for patients.
Owner:ZHEJIANG GUOYUE TECH CO LTD

Donor heart preservation method based on crystal cardioplegic solution and UW solution and application of donor heart preservation method

PendingCN119969379ADead animal preservationHeart cellsCells heart
The invention discloses a donor heart preservation method based on a crystal cardioplegic solution (CC solution) and a UW solution and application of the donor heart preservation method, and belongs to the field of biomedical engineering. The method comprises the following steps: (a) preparing CC liquid; (b) perfusing CC liquid through the aorta at the pressure of 150mmHg for 3-5 minutes to cause cardiac arrest; (c) taking out the heart, and performing secondary perfusion with 2000ml of 4 DEG C UW solution for 8-12 minutes; and (d) immersing the heart into a UW solution for cold preservation, wherein the cold ischemia time is less than or equal to 8 hours. In combination with a CC liquid perfusion step, the protection effect of the cold preservation liquid is remarkably improved by reducing the metabolic rate of cardiac cells; through double perfusion of CC liquid and UW liquid, optimization of metabolic balance and effective inhibition of inflammatory response are realized in the cold storage process of the heart; the invention has the functions of prolonging cold ischemia time and keeping heart cells, and provides a new technical means for long-time cold preservation.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Sudden cardiac arrest prediction method and device, equipment and storage medium

The invention relates to a cardiac arrest prediction method, device and equipment and a storage medium, relates to the technical field of cardiac arrest risk prediction, fully captures a complex mode and trend of a patient capable of supporting a heart state of a current breathing mode at any time and time, and performs accurate early warning before cardiac arrest really occurs. Comprising the steps that in the process that a breathing machine is used for assisting a user in breathing, first interaction parameters actually generated by the breathing machine are collected every unit time; the first interaction parameter refers to a parameter for measuring a receiving state of specific oxygen input by a human body to the breathing machine; inputting a first interaction parameter collected at the current time as event information into a breathing mode prediction network under a heart state constructed based on a long-short-term memory network, and updating a target cell state of the breathing mode prediction network under the heart state at the current moment; and outputting the risk probability calculated by the breathing mode prediction network in the heart state.
Owner:XIANGYA HOSPITAL CENT SOUTH UNIV +1

Method and equipment for improving cardiac arrest resuscitation (Pocket Crash Cart)

Method and equipment for improving cardiac arrest resuscitation (Pocket Crash Cart) includes:1. Manual or Automatic Pocket Crash Cart which attaches to the patient via IV / OS to allows quick and accurate administration of emergency medication manually or remotely.2. The software for mirroring display screen of manual defibrillator or AED / computer / laptop / phone and video cameras allowing to transfer patient information from the Cardiac Arrest scene especially in hard-to-reach locations (cruise ship, expeditions) to CMF via internet for expert advice and / or administration of emergency medication in the absence of ASLC provider.
Owner:FREEMAN TAMARA ALIZA

Method, system and apparatus for a ai-optimized and video-directed CPR process in a cardiac arrest

The system provides a real-time video and audio communication with a 911 call center to perform effective CPR on a patient experiencing OHCA with real-time monitoring and feedback. The system includes a Mobile App that communicates with a smart phone with camera, a wireless remote-CPR equipment stand and emergency CPR kit. The mobile app will automatically send a link to a caregiver's cell phone responsive to a 911 call placed by the caregiver, to establish a secured video call via which the 911 center can guide the caregiver in performance of CPR until an ambulance arrives. This integrated description provides a comprehensive overview of the AI-driven CPR guidance system, detailing its core components, operational workflow, training processes, and scalability. By combining real-time coaching, advanced diagnostics, and EMS coordination, the system offers a groundbreaking approach to improving OHCA outcomes.
Owner:SHEN ANNABELLE +1

Dynamic Early Warning System for Cardiac Arrest Based on Multimodal Data Fusion

ActiveCN120114012BMedical data miningHealth-index calculationEngineeringAbnormal heart rate
The present invention discloses a dynamic early warning system for cardiac arrest based on multimodal data fusion, belonging to the field of medical information technology. Specifically, it includes: a non-contact sensing module for continuously acquiring the physiological parameters of a user based on non-contact devices; an active wearing module for starting the acquisition of contact physiological parameters when the user actively triggers the wearing device; a scene adaptive module for constructing a physiological parameter baseline only based on non-contact sensing data when the wearing device is not triggered; when the user triggers the wearing device, cross-verifying the contact data and the non-contact data and correcting the calibration parameters of the non-contact data; a risk decision module for starting a forced verification process of contact data when the non-contact detection detects an abnormal heart rate; if the verification fails or there is no response, generating a corresponding risk level early warning based on the continuous abnormal duration and the fluctuation pattern; the present invention realizes dynamic early warning based on multimodal data.
Owner:FUJIAN PROVINCIAL HOSPITAL

Automatic epinephrine injection patch for cardiovascular first aid

InactiveCN120860450AMedical devicesSensorsMedication injectionEpinephrine injections
The invention provides an epinephrine automatic injection patch and method for cardiovascular first aid, and the injection patch comprises a flexible biosensing layer which obtains the subcutaneous impedance value and vital sign parameters of a patient; the microneedle array is used for adjusting the penetration depth based on the subcutaneous impedance value and controlling the deformation quantity through a piezoelectric actuator; the micro-fluidic pulse drug delivery module is connected with the micro-needle array and is used for executing pulse type drug injection according to the penetration depth; and the control module is used for judging an autonomous circulation recovery state based on the vital sign parameters and triggering the microfluidic pulse administration module to stop injection. According to the application, by constructing a first-aid closed loop of'multi-mode physical sign dynamic monitoring-self-adaptive microneedle administration-ROSC intelligent termination ', the response speed of epinephrine injection is increased, the bioavailability is improved, the risk of excessive medication is reduced, and the gold rescue efficiency and the neurological function prognosis rate of pre-hospital cardiac arrest patients are remarkably improved.
Owner:SHANDONG UNIV QILU HOSPITAL

Establishment method and application of traumatic hemorrhagic sudden cardiac arrest rat model

The invention discloses an establishment method and application of a traumatic hemorrhagic sudden cardiac arrest rat model, a rat is used as an experimental subject, a researcher can accurately adjust the hemorrhagic degree in an animal model by controlling the bloodletting speed and amount to better control experimental conditions, the repeatability and reliability of experimental results are ensured, and the method has the advantages of being high in operability and high in reliability. In the model building process, not only is the factor of blood loss considered, but also tissue damage caused by laparotomy is combined, physiological changes under the combined action of multiple factors after trauma are reflected more comprehensively, and the complexity and authenticity of the model are improved; the method has the advantages that the operation is simple, the experiment cost is lower, the repeatability is high, the scale and frequency of cardiac arrest research experiments are not limited, the experiment result has higher reliability and generalizability, and the method not only can be used for basic medical research and exploration of the pathophysiology mechanism of traumatic hemorrhagic shock, but also is suitable for pharmacological research, and has a wide application prospect. The effectiveness of new drugs or therapies for improving prognosis is assessed.
Owner:SECOND AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE

Thoracic cavity monitoring and first-aid device for department of cardiology

The invention relates to the technical field of cardiology department medical devices, and discloses a cardiology department thoracic cavity monitoring first-aid device which comprises a shell, the shell is worn on the chest of a patient through a chest bandage, an external chest compression mechanism is arranged on the shell, and the external chest compression mechanism comprises a first air bag arranged at the bottom of the shell; the shell is connected with an electrode plate for monitoring the respiration and the heart rate of a patient; a rotating disc is rotationally arranged on the shell, an inflation assembly is arranged on the rotating disc, a first air vent is formed in the rotating disc, a second air vent and a communicating groove are formed in the shell, and the second air vent communicates with an inner cavity of the first air bag through the communicating groove. According to the thoracic cavity monitoring and first-aid device for the department of cardiology, through a simple wearing device, when breathing and cardiac arrest of a patient are monitored, first-aid measures of cardio-pulmonary resuscitation can be automatically carried out, autonomous circulation and autonomous breathing are promoted, vital signs of the patient are helped to be gradually recovered, and irreversible damage to the brain and the body of the patient is avoided.
Owner:CHENGDU CHENGNAN JINHUA HOSPITAL CO LTD +1

Monitor / defibrillator with advanced patient specific treatment protocol

PCT designated stage expiredWO2025012394A1Heart defibrillatorsHeart stimulationCardiac arrest- pulseless electrical activityVentricular tachycardia
The present disclosure provides methods, systems and devices for guiding, a treatment of a patient experiencing sudden cardiac arrest, by a responder and / or a mechanical CPR device, in accordance with a patient specific treatment protocol. This protocol conditionally implements a pulseless electrical activity protocol when a rhythm classification of an electrocardiogram of the patient is a non-shockable cardiac rhythm with electrical activity and a pulse indication is the absence of the pulse of the patient, or an asystole protocol when the rhythm classification of the electrocardiogram of the patient is a non-shockable cardiac rhythm without electrical activity, or a return of spontaneous circulation protocol when the rhythm classification of the electrocardiogram of the patient is the non-shockable cardiac rhythm with electrical activity and the pulse indication is the presence of the pulse of the patient, or a ventricular fibrillation / ventricular tachycardia protocol when the rhythm classification of the electrocardiogram of the patient is a shockable cardiac rhythm.
Owner:KONINKLIJKE PHILIPS NV +1

Sudden cardiac arrest dynamic early warning system based on multi-modal data fusion

ActiveCN120114012AMedical data miningHealth-index calculationEngineeringAbnormal heart rate
The invention discloses a sudden cardiac arrest dynamic early warning system based on multi-modal data fusion, and belongs to the technical field of medical information, and the system specifically comprises a non-contact sensing module which is used for continuously obtaining physiological parameters of a user based on a non-contact device; the active wearing module is used for starting contact type physiological parameter acquisition when a user actively triggers the wearable equipment; the scene self-adaption module is used for constructing a physiological parameter base line only based on the non-contact sensing data when the wearable equipment is not triggered; when the user triggers the wearable device, performing cross validation on the contact data and the non-contact data, and correcting calibration parameters of the non-contact data; the risk decision module is used for starting a contact type data forced verification process when the heartbeat frequency is detected to be abnormal in a non-contact manner; if verification fails or no response is made, corresponding risk level early warning is generated based on the continuous abnormal duration and the fluctuation mode; according to the invention, dynamic early warning is realized based on multi-modal data.
Owner:FUJIAN PROVINCIAL HOSPITAL

Portable emergency response kits with integrated signal transmission system

PendingUS20260060855A1First-aid kitsMedical equipmentOpioidergicOpioid overdose
A portable emergency response kit designed for rapid intervention in opioid overdose or cardiac arrest scenarios comprises a durable case with compartments for specific medical devices, such as opioid overdose treatment medication or an Automated External Defibrillator (AED). The case features a breakable closed circuit that is, upon opening, triggered to send a signal to notify emergency medical services (EMS) or predefined contacts of the kit's location.The system utilizes GPS module and may include dual-mode communication capabilities for reliable alert transmission in various environments. Additional features may include a transparent case material for visual confirmation of contents, tamper-evident seals, QR codes linked to instructional content, and a battery power source. The kit is designed to be user-friendly, incorporating ergonomic elements and optional accessories for enhanced portability and storage, ensuring rapid and effective response in critical situations.
Owner:FFF ENTERPRISES

Construction method and application of neurological function prognosis prediction model after cardio-pulmonary resuscitation

The invention discloses a construction method and application of a neurological function prognosis prediction model after cardio-pulmonary resuscitation, and the method comprises the steps: obtaining clinical data of a patient reaching spontaneous circulation recovery after cardio-pulmonary resuscitation, and screening a clinical patient meeting a discharge standard; taking brain function classification as dependent variables, respectively adopting an LASSO regression analysis method and a Boruta feature screening method to screen feature variables, and selecting common feature variables; constructing a plurality of machine learning models based on the common feature variables, and drawing an ROC curve and a decision curve corresponding to each machine learning model; carrying out discrimination evaluation on the machine learning model by adopting AUC, evaluating clinical benefits of the machine learning model by adopting a decision curve, and screening an optimal prediction model; and explaining the optimal prediction model and the common feature variables by adopting an SHAP tool. The prediction model constructed by the invention can conveniently and quickly predict the prognosis condition of the neurological function within 24 hours after sudden cardiac arrest and resuscitation.
Owner:TIANJIN MEDICAL UNIVERSITY GENERAL HOSPITAL

Intelligent method and system for quickly getting AED to emergency scene, device, and medium

The present application discloses an intelligent method and system for quickly getting an AED to an emergency scene, a device, and a medium. The method comprises: acquiring distress call information of an emergency event and the geographical location of an emergency scene; performing first AED search range calculation, second AED search range calculation and third AED search range calculation; and AED delivery personnel getting an available AED from an available AED location corresponding to the fastest AED access plan and delivering the AED to the emergency scene. The system comprises an emergency mobile terminal, an intelligent AED device and an emergency cloud platform. The use of the plan in the present application can provide a good solution for passersby to participate in cardiac arrest first aid, accurately, scientifically and effectively allowing passersby to participate in cardiac arrest first aid; moreover, the possibility of passersby responding can gradually increase with the popularization and application of AEDs, providing another boost for patients to receive timely medical treatment, thereby further ensuring the life safety and health protection of patients.
Owner:PRIMEDIC (JIANGSU) MEDICAL SCI & TECH CO LTD +1

Display module of electrode pads for external defibrillators

1. Name of the Design Product: Display Module of Electrode Pad for External Defibrillator. 2. Use of the Design Product: Electrically connected to a defibrillation device, attached to the human body surface to assist the operator in rescuing a patient with cardiac arrest symptoms, and at the same time display the effective use date of the electrode pad. 3. Design Key Points of the Design Product: Lies in the shape of the claimed part. 4. Picture or Photograph Most Indicating the Design Key Points: Perspective View. 5. Other Circumstances Requiring Explanation: Other Explanation: The area covered by blue in this design product represents the content not protected by this case.
Owner:PRIMEDIC (JIANGSU) MEDICAL SCI & TECH CO LTD +1

Medical double-core-layer pressure-resistant sensing balloon and preparation method thereof

The invention discloses a medical double-core-layer pressure-resistant sensing balloon and a preparation method thereof.The medical double-core-layer pressure-resistant sensing balloon comprises a balloon body connected with a catheter, the balloon body is of a double-core-layer shell layer structure, and a core layer comprises a developing and pressure sensing double-core structure; a developing agent is loaded in the inner core layer balloon, the position of the balloon is effectively displayed, it can be guaranteed that the core layer is not affected after the outer layer is damaged, the inner layer and the other core layer balloon can synchronously conduct pressure sensing, and the shell layer is a compression layer with toughness and bursting pressure and can be coated with a medicine coating. According to the medical double-core-layer high-pressure-resistant balloon provided by the invention, through the design of the internal double core layers, accurate control of pressure is effectively realized, and the problem that a developing agent leaks out of the brain after the outer layer of the balloon is broken in a trigeminal nerve minimally invasive puncture balloon compression operation is prevented; and by controlling the surface roughness of the outer layer, medicine coating can be carried out, so that vagus nerve reflex is prevented, and the problem of high risks of sudden blood pressure rise and sudden heartbeat arrest caused by compression in the operation process is solved.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE +1

Sudden cardiac arrest monitoring camera in hospital and recognition alarm system thereof

The invention discloses a cardiac arrest monitoring camera in a hospital and an identification alarm system thereof, and belongs to the technical field of heart system monitoring, the cardiac arrest monitoring camera comprises a support and a camera main body installed on the support, and the camera main body is provided with a transparent window for protecting a lens. And the shell of the camera main body is provided with a needle swinging mechanism capable of automatically cleaning the transparent window. After a driving wheel rotates under the action of a driving motor, the driving wheel can be matched with a connecting wheel to drive a driven wheel to rotate on a shell, the driven wheel drives a threaded rod to rotate, and under the action of meshing connection, a moving block moves left and right on the threaded rod so as to be matched with a connecting rope to drag a sliding toothed plate. When the moving block moves in the direction close to the driven wheel, the moving block can be matched with the connecting rope to drive the sliding toothed plate to move rightwards at the front end of the shell, and therefore under the action of the semicircular toothed ring and the sliding toothed plate, the swing rod is adjusted to swing anticlockwise on the transparent window, and dust on the transparent window is scraped away.
Owner:崔晓桐

Cardiopulmonary resuscitation education system and method based on application specialized for schools

PCT designated stage expiredWO2025116504A1Data processing applicationsEducational modelsEmergency procedureCardiorespiratory arrest
A cardiopulmonary resuscitation education method based on an application specialized for schools, according to the present invention, comprises the steps of: when a patient in cardiac arrest is found within a school, transmitting, by a person who has first found the patient, a rescue request to an emergency medical response team (SMART) through an application installed on his or her terminal; displaying a rescue request notification on a terminal of each team member of the SMART; automatically assigning, by an emergency procedure model, a main role and a plurality of sub-roles on the basis of the distance from the patient; transmitting a rescue request to team members who are a certain distance or more away from the patient; and providing a step-specific emergency procedure method for each of the main role and the sub-roles in real time through image, speech, and subtitle guidance.
Owner:COSMOS MEDIC INC

Response system with emergency response equipment locator

An automated external defibrillator (AED) management system includes an AED information database including location information for a plurality of AEDs, and contact information for notifying an owner or administrator of a respective AED. The system further includes a notification system communicatively coupled to the AED information database, the notification system configured to receive a request to alert responders in a vicinity of a cardiac arrest victim, receive a location of the cardiac arrest victim, identify at least one AED located in the vicinity of the cardiac arrest victim from the location information for the plurality of AEDs, provide an alert to the owner or administrator of the at least one AED located in the vicinity of the cardiac arrest victim based on the contact information, wherein the alert comprises a request for the owner or administrator to bring the AED to the location of the cardiac arrest victim.
Owner:ZOLL MEDICAL CORPORATION

Sudden cardiac arrest treatment device based on ultrasonic Doppler feedback technology

The invention relates to a sudden cardiac arrest treatment device based on an ultrasonic Doppler feedback technology, and belongs to the field of medical instruments. The cardiac arrest treatment device based on the ultrasonic Doppler feedback technology comprises a first monitoring module used for monitoring the blood flow condition of the neck blood vessel of a target organism; and / or the second monitoring module is used for monitoring the blood oxygen condition of the neck blood vessel of the target organism; the acquisition module is used for acquiring blood supply and / or oxygen supply of the target organism according to the blood flow condition and the blood oxygen condition; the system comprises a blood supply module, a cardio-pulmonary resuscitation pressing module, and / or a ventilation module, and / or a defibrillation module, and the cardio-pulmonary resuscitation pressing module is used for adjusting the pressing depth or pressing frequency according to blood supply and / or oxygen supply; the ventilation module is used for adjusting the ventilation frequency in the cardio-pulmonary resuscitation pressing process according to blood supply and / or oxygen supply; the defibrillation module is used for executing defibrillation operation under the condition that the defibrillable heart rhythm exists. According to the technical scheme, the treatment rate can be increased, and the cardiac arrest treatment quality can be improved.
Owner:SUZHOU SENSUS MEDICAL TECH CO LTD

System and method of noninvasive blood flow measurement during cardiopulmonary resuscitation using signal gating

In some embodiments, a blood flow sensor device such as a non-invasive cardiac arrest monitor (NICAM) that uses ultrasound to detect blood flow is used to monitor blood flow during cardiopulmonary resuscitation. One or more gating signal generation devices transmit gating signals to a blood flow monitoring computing device. The blood flow monitoring computing device uses the gating signals to determine time periods during which blood flow information generated by the blood flow sensor device is most likely to be accurate. The blood flow monitoring computing device measures blood flow during the time periods. In some embodiments, the blood flow monitoring computing device presents the measured blood flow to a user. In some embodiments, the blood flow monitoring computing device transmits a command to a chest compression device based on the measured blood flow.
Owner:UNIV OF WASHINGTON +1

Novel liquid body temperature circulation temperature control equipment

The invention relates to novel liquid body temperature circulation temperature control equipment, and belongs to the technical field of medical temperature control equipment. The device comprises an equipment base, a temperature control host, a stand column, a T-shaped installation frame, a pipeline assembly, a temperature control assembly and a temperature sensing assembly, the stand column is fixedly installed above the equipment base, the temperature control host is installed on one side of the stand column, the T-shaped installation frame is fixedly installed above the stand column, a lifting hook is installed below the T-shaped installation frame, and the pipeline assembly is installed above the lifting hook. The temperature control assembly is fixedly installed on one side of the temperature control host, and the temperature sensing assembly is installed on one side of the lower portion of the temperature control host. The temperature control equipment monitors the pipeline output temperature and the core body temperature of a patient in real time through the temperature sensing assembly, the temperature control host adjusts the temperature control power in a closed-loop feedback mode based on monitoring data, accurate, rapid and stable temperature control is achieved, the equipment is suitable for various clinical scenes needing mild hypothermia intervention such as thermoplegia and the syndrome after cardiac arrest, treatment safety and effectiveness are improved, and the treatment cost is reduced. And the workload of medical staff is reduced.
Owner:THE 960TH HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE

Respiratory-cardiac arrest detection and drug overdose treatment system

PendingUS20250375157A1SensorsDiagnostic recording/measuringBenzodiazepineExpired drug
The invention system is a wearable device that detects an impending or onset of cardio-respiratory arrest and remediates the condition by injecting an appropriate reversal drug depending upon the drug that triggered the arrest. It can detect and remediate arrests caused by drugs such as opioids, benzodiazepine or alcohol. Using self-test and other checks, it ensures that the system is operationally ready and that no near-expiration or expired drug is administered.
Owner:SASSANO JOHN

Application of STING inhibitor in preparation of medicine for treating or preventing post-cardiac arrest syndrome

The invention relates to the field of biological medicine, in particular to application of an STING inhibitor in preparation of a medicine for treating or preventing post-cardiac arrest syndrome. According to the invention, STING-mediated I-type interferon activation is inhibited through the intervention effect of the STING inhibitor, so that brain injury of a patient suffering from the post-cardiac arrest syndrome is relieved, and the survival rate and prognosis of the patient are improved.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Application of N6022 in improvement of cerebral injury after cardiac arrest resuscitation

The invention discloses an application of N6022 in improving brain injury after cardiac arrest resuscitation, and particularly relates to an application of N6022 or a derivative thereof given through a nose in improving the brain injury after cardiac arrest resuscitation and increasing the survival rate after cardiac arrest resuscitation. Compared with the prior art, the application has the advantages that the increased GSNOR enzyme activity of brain tissues after sudden cardiac arrest resuscitation can be effectively inhibited by nasal injection of N6022 into a sudden cardiac arrest resuscitation rat model; the N6022 can effectively improve the neurological function after cardiac arrest resuscitation and increase the survival rate after cardio-pulmonary resuscitation; n6022 is used for inhibiting the activity of GSNOR, so that the number of survival neurons of brain tissues after sudden cardiac arrest resuscitation can be increased; the delivery mode of the N6022 through the nose can effectively enable the N6022 to enter the brain tissue of the rat. According to the invention, a new application field of N6022 is developed, and a meaningful reference is provided for improving the cerebral function after sudden cardiac arrest resuscitation.
Owner:THE PEOPLES HOSPITAL WEIFANG CITY CN0

Real-time methods to enable precision-guided CPR to improve neurological outcome and predict brain damage after ischemic injury and reperfusion

A multimodal optical imaging platform is used to obtain cerebral perfusion-metabolism mismatch metrics for rapid assessment of acute brain injury, ongoing (real-time) feedback to optimize cardiopulmonary resuscitation to improve neurological outcome, and rapid prognosis of recovery. Light of several wavelengths and types is delivered to the tissue, which is then absorbed and scattered by tissue components such as blood and cellular components. Some of this light scatters back to the surface, where it is captured by a detector. The resulting data are processed to obtain blood flow and oxygenation parameters, as well as tissue scattering. These parameters are then combined to calculate metabolism and flow-metabolism coupling / decoupling metrics, which are used to determine ischemic damage, ongoing need for optimal blood flow and oxygenation, and to predict cerebral recovery in patients with acute brain injury during and immediately after cardiac arrest, stroke, traumatic brain injury, etc.
Owner:RGT UNIV OF CALIFORNIA