The present invention discloses a human body affinitive lubricating protective and repair gel, which combines photocatalyst (TiO2) particles with a disinfection material such as nano silver to produce a TiO2Ag compound, and mixes the compound with a filtered natural biological organism with a molecular weight below 50 Kbp and a concentration of 0.05˜5% including small molecules of collagen, chitin, chitosan, hyaluronic acid, vitamin C, and nano iron, and its pH value is adjusted to 6 which is close to the pH value of our skin, and thus the mixture constitutes a gel affinitive to human skins and non-toxic to human cells. An accessory ingredient such as an aromatic agent, a detergent, or a cosmetic agent is added in the manufacturing process to produce an emulsion or a paste for coating or spraying, which is used as a health or sanitation item such as a hand liquid soap, a cosmetic, a shampoo, or a disinfectant. The feature of the small diameter of the particles (1˜100 n/m) can penetrate the cuticle of our skin and remain at the derma inside the skin pores to produce a protective film, and the collagen can be absorbed by the skin to give the effects of repairing tissues, stopping bleeding, and lubricating skins. With the cyclic disinfection effect of the TiO2Ag compound, a deeper clean skin to prevent germs is obtained and a disinfection effect is achieved to eliminate acnes and pimples. The present invention also makes use of an oxidation-reduction mechanism of the photocatalyst (TiO2) to achieve long-hour disinfection and naturally remove germs.