A kinetic anchoring deployment system utilizing a high-impulse, high-velocity anchor launching mechanism is described herein. The assembly generally has a handle, a flexible elongate body, and a launch assembly thereupon. The launch assembly uses a number of different mechanisms for creating a high-impulse shock wave for launching a carriage carrying a tissue anchor, e.g., combustible materials, rapid vaporization of a fluid, hydraulic energy transmission, laser energy, compression springs, electromagnetic energy, etc. The deployment system may be advanced intravascularly and/or intraluminally within a patient body for treating a number of different indications.