16 results about "Subarachnoid space" patented technology

The application discloses a lumbar puncture auxiliary mechanism and a use method thereof. The lumbar puncture auxiliary mechanism comprises a main body assembly, a supporting shell fixed to one side of a positioning disc, and a puncture needle penetrating through the positioning disc and the supporting shell. The main body assembly is provided with an adjusting assembly in the supporting shell. The adjusting assembly comprises a driving element arranged on one side of the positioning disc, a transmission element arranged on one side of the driving element, and an adjusting element arranged on one side of the transmission element. The adjusting element comprises a limiting shell fixed to the inner wall of the supporting shell, a rack sliding in the limiting shell, and a first spring fixed to the end of the rack. The adjusting assembly can intermittently supply the puncture needle, so that the puncture needle can smoothly break through the yellow ligament without improper force. The puncture process can be judged, so that the time when the puncture needle enters the epidural space and the subarachnoid space can be accurately grasped, and the accidental damage to the human body is reduced.

This utility model discloses an anesthesia puncture needle, including an outer needle tube and a needle hub connected to one end of the outer needle tube; it also includes an inner needle body nested inside the outer needle tube, with one end extending to the outside through the opening of the outer needle tube, and the other end extending into the needle hub. The protruding end of the inner needle body is conical, and at least one collection hole is opened on its outer wall near the end. This utility model relates to the field of medical anesthesia technology. This anesthesia puncture needle, through the cooperation of the inner needle body and the outer needle tube, can facilitate the puncture needle to enter the subarachnoid space. At the same time, it can pull the piston collector to draw cerebrospinal fluid from the end of the inner needle body and store it in the internal cavity of the piston collector, so that it can be mixed with the colorimetric solution injected through the colorimetric branch tube, thereby enabling colorimetric treatment of the cerebrospinal fluid, facilitating rapid diagnosis by medical personnel. In this process, the colorimetric solution will not come into contact with the human body, avoiding harm to the human body.

This utility model discloses a lumbar puncture needle with monitoring function, comprising: a needle body, with a puncture needle main body internally connected to the needle body. The puncture needle main body is used to detect puncture depth and monitor cerebrospinal fluid pressure. The puncture needle main body includes an outer needle and an inner needle, with the inner needle located inside the outer needle. A gap is reserved between the outer and inner needles. A signal receiving mechanism is provided at the top of the outer needle. Both the outer and inner needles are electrically connected to the signal receiving mechanism via a point-to-line connection. This utility model provides a lumbar puncture needle with monitoring function, consisting of a system and a puncture needle main body. It can issue an alarm when the puncture needle tip contacts the cerebrospinal fluid in the subarachnoid space of the lumbar spine, and can monitor the cerebrospinal fluid pressure in real time during cerebrospinal fluid collection. Through precise puncture depth feedback and real-time cerebrospinal fluid pressure monitoring, doctors can more accurately locate the puncture point, reduce surgical errors, and improve the success rate of surgery. Real-time monitoring of cerebrospinal fluid pressure helps to detect abnormal intracranial pressure in a timely manner, prevent serious complications such as brain herniation, and ensure patient safety.

The present disclosure is directed towards devices, methods, and related systems that are minutely-invasively delivered to the brain parenchyma, subdural or subarachnoid space where the devices, methods, and systems directly interface with central nervous system media (i.e., fluid or tissue) enabling detecting, sensing, measuring, stimulating, altering and / or modulating of the media or tissue surfaces.

The application discloses a method, device and equipment for evaluating the width and narrowness degree of the subarachnoid space of the optic nerve, and the method comprises the following steps: collecting a target image corresponding to a target position of the optic nerve, and obtaining the resolution of the target image, wherein the target position is any one of a plurality of preset positions on the optic nerve; dividing the subarachnoid space of the optic nerve in the target image into at least two regions by using at least one division line, the division line passes through the centroid of the optic nerve sheath in the target image, and the target circle central angle is bisected, the target circle central angle is the central angle of a circle with the centroid as the center and an arbitrary length as the radius; evaluating whether the target image meets the first evaluation standard based on the images of the at least two regions and the resolution of the target image; in this way, the defect that the MR image cannot be effectively judged whether it can be used for evaluating the width and narrowness degree of the subarachnoid space of the optic nerve can be solved, and the subarachnoid space of the optic nerve can be equally divided to the maximum extent, so that the final evaluation result is more accurate and more persuasive.

The invention provides a construction method of a spinal cord injury animal model for maintaining the integrity of subarachnoid space, which comprises the following steps: adopting a mammal with spinal cord injury, clamping and closing the opening of the dura mater of the mammal, dripping biological glue in alignment with the clamped and closed position, and suturing after the biological glue becomes frost and the dura mater is adhered together. The invention also provides application of the spinal cord injury animal model for maintaining the integrity of the subarachnoid space in research on motor function, nervous tissue recovery or tissue morphology recovery of animals after spinal cord injury. The application shows that after experimental spinal cord injury is caused, the motion function and histomorphological recovery of a mouse can be improved by tightly suturing the dura mater.

Magnetic resonance imaging (MRI) is used to image the slow flow of cerebrospinal fluid (CSF) in subarachnoid and perivascular spaces, amongst other regions of the brain and central nervous system. The slow CSF flow imaging can be provided by using low velocity’ encoding (VENC) and an efficient data acquisition. Tailored image processing can be used to further improve the accuracy, specificity, and visualization of CSF flow dynamics.

The invention relates to an anchoring mechanism and a device for percutaneous interventional therapy of hydrocephalus, the device comprises a shunting unit, the shunting unit comprises a shunting tube body, a one-way valve and an anchoring mechanism, the anchoring mechanism comprises a fixing part and an anchoring rod, one end of the anchoring rod is connected with the fixing part, the other end of the anchoring rod is a free end, and the anchoring mechanism is connected with the other end of the anchoring rod in an anchoring state. And the anchoring rod deviates relative to the fixed part, or the anchoring rod deviates from the shunting pipe body, so that a space for anchoring is formed. The invention provides a brand new anchoring mechanism which does not relate to an expansion structure, so that the volume of the device in the subarachnoid space can be reduced, and the intracranial occupation is reduced; the device can be used for treating hydrocephalus through an intervention method, open surgical operation is not involved, trauma is reduced during operation, surgical operation time is saved, the contact area of the device and blood is reduced, and therefore the risk of central nervous system injury and blood-related complications is reduced; and the possibility of postoperative infection can be greatly reduced by matching with an anchoring mechanism.

Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.

The invention relates to the technical field of augmented reality medical training, in particular to a subarachnoid space puncture training system based on augmented reality, which comprises a scene loading module, a process control module, a visualization processing module, a synchronous explanation module and an interaction control module. The system loads a three-dimensional anatomical or panoramic video training scene according to the selection of a user, and starts a four-stage progressive training process. And carrying out transparency gradient processing on the three-dimensional human body model through material rendering control, and dynamically generating an anatomical structure visualization effect from the skin to the deep tissue. And the synchronous explanation module activates the dynamic annotation system, displays the corresponding anatomical annotation according to the training stage, and synchronously plays voice explanation and subtitles based on the time axis. The interaction control module responds to the user operation instruction and controls the playing state of the training process. According to the system, progressive visualization of an anatomical structure and accurate and synchronous explanation of training content are realized, and the immersion, coherence and teaching effect of training are improved.

Disclosed herein are methods and systems configured to distribute multiple fluids towards a target area. The target area may comprise a nerve ending within a patient's intrathecal space retaining cerebrospinal fluid (CSF). At least one fluid of the multiple fluids may be a therapeutic fluid comprising a medication. The distribution may be controlled to adjust a baricity of the therapeutic fluid with respect to the CSF, to provide more effective distribution towards the target area. An implementation may consider fluid densities, fluid flow rates, relative position and spatial orientation of the target area with respect to a point of fluid distribution to determine and control the fluid distribution toward the target area. An implementation may individually adjust fluid flow rates from multiple reservoirs to adjust therapeutic fluid baricity, dynamically modulate fluid extraction and aspiration through the intrathecal space using barbotage and respond to device or patient spatial orientation, permitting precise therapeutic fluid distribution prescriptions.

The application belongs to the field of biological medicine, and particularly relates to a drug for treating EGFR mutant non-small cell lung cancer meningeal metastasis, application, a medicine box and a preparation method of the drug, the drug is a lyophilized powder preparation or injection solution for subarachnoid injection of EGFR-TKIs, the amount of EGFR-TKIs in the drug is 0.01-5 mg per person, and the injection method comprises any one of lumbar puncture, injection through a catheter indwelled in the pre-bridge pool and Ommaya capsule injection. The prepared EGFR-TKIs injection solution can be directly injected into the subarachnoid space, greatly improving the drug concentration in the cerebrospinal fluid of the patient, the cerebrospinal fluid / plasma concentration ratio is increased from far less than 1 to more than 2 times, and even more than 10 times. The application can completely solve the problem of insufficient dose caused by the blood-brain barrier after oral administration of a targeted drug, and the drug has fast effect and can significantly improve the treatment effect of lung cancer meningeal metastasis.

The invention is directed to a method and apparatus for early warning of cerebral vasospasm after subarachnoid hemorrhage using brain imaging equipment to identify blood leakage within the subarachnoid space to detect brain zones with increased risk of cerebral vasospasm.

The application relates to the field of interventional medical technology, in particular to a percutaneous interventional venous sinus puncture access device. The access device is formed by the mutual cooperation of a balloon catheter, a deflecting catheter and a puncture guide wire, can puncture into the subarachnoid cavity in the cranial cavity on the venous sinus without damaging the brain, break the dura mater and arachnoid, construct a stoma between the pontocerebellar angle pool and the inferior petrosal sinus, and make the cerebrospinal fluid flow from the subarachnoid cavity to the venous sinus, to the jugular vein and to the heart, and participate in blood circulation. The access device can also be used for delivering a shunt, so that the hydrocephalus which can only be effectively treated by operation in the past can be treated by a minimally invasive interventional method, the access device is not used for surgical open operation, the intraoperative trauma is reduced, the operation time is saved, and the possibility of postoperative infection is greatly reduced.

The invention belongs to the technical field of hydrocephalus operation equipment, and particularly relates to a cerebrospinal fluid shunting device. According to the flow dividing device, the biocompatible coating is arranged on the expansion support, and the biocompatible coating has the water absorption expansion characteristic, so that the weight of the coating after water absorption is increased, and under the limiting effect of the gravity of the biocompatible coating after water absorption, the expansion support is prevented from further expanding; the water-absorbing biocompatible coating enables the expansion stent to be clung to the blood vessel wall at the brain pool as much as possible, so that the volume of the expanded expansion stent is reduced, the expansion of the expansion stent and the water-absorbing weight of the biocompatible coating are relatively balanced, the volume of the subarachnoid space where the expansion stent is located cannot be excessively increased, and the expansion stent is more stable in expansion. Therefore, the risk of injury to a central nervous system caused by surgical operation and a shunting device is reduced.