A drug delivery system for the prevention of cerebral vasospasm
A technology for cerebral vasospasm and drugs, applied in the field of compound delivery systems, which can solve the problems of lack of effectiveness, time-consuming, side effects, etc.
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[0142] The present invention relates to a delivery system for delivering therapeutic agents to cerebral arteries to prevent or reduce the severity of cerebral vasospasm. More specifically, the present invention relates to delivery systems for the delivery of drugs to cerebral arteries that prevent or reduce the severity of cerebral vasospasm. Unlike previously studied existing therapeutic methods including intravenous and intraarterial drug delivery, the present invention provides a drug delivery system that delivers therapeutic agents to specific regions around cerebral arteries, which achieves local release of the drug and through Reduced delayed cerebral ischemia (DCI) caused by cerebral vasospasm leads to better efficacy. In one aspect, the invention provides the use of a transient receptor potential protein blocker as an active substance that blocks channels that are believed to be alternative pathways that are activated during the development of vasospasm.
[0143] In o...
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