31 results about "Cerebral ventricular" patented technology

Apparatus for directed cranial access to a site includes a guidepiece and a receptacle. The receptacle includes a lower part having a rim and a base, and a hollow stem at the base adapted to be mounted in a hole in the skull; and an upper part having a rim and an opening at the top. Each part of the receptacle has an interior spherical surface, and they can be joined at the rims to form an inner surface enclosing a spherical interior. The guidepiece includes a body having a spherical outer surface and a cylindrical bore through the center, defining an alignment axis; and a guide tube in the bore. The guidepiece is dimensioned to fit rotatably within the receptacle interior, and the apparatus is assembled by joining the receptacle over the guidepiece body, with the guide tube projecting through the top opening. The guide tube is dimensioned to accept an imaging device such as an ultrasound probe during an imaging stage, and an adaptor is provided, dimensioned to accept a device to be placed at the site during a placement stage. The probe is inserted into the guide tube and the guidepiece is swiveled until the image shows that the alignment axis is aligned along an optimal trajectory to the site, the receptacle is tightened to lock the guidepiece, and the imaging device is withdrawn. Then the adaptor is inserted into the guide tube, and the device is inserted through the adaptor along the established trajectory to the site. After placement of the device into the intracranial target, the adaptor, guidepiece, and receptacle are removed as a unit over the device while the device is held in place.

The invention discloses an image processing method and device, and the method comprises the steps: carrying out training of a deep convolutional neural network through a first sample set containing abrain image marked with a ventricular segmentation result, and then segmenting the brain image through the deep convolutional neural network, so that the obtained segmentation result is quick, accurate and robust; determining the position of the actual midline plane of the brain image through the segmentation result, so that the obtained position of the actual midline plane is more accurate; and finally, comparing the position of the actual midline plane with the position of the theoretical midline plane to determine the image processing result of the to-be-detected brain image of the image. Therefore, the purpose of automatically judging brain structure displacement is achieved, the influence of whether the posture of the brain image is set right or not on the recognition result is greatly reduced, the posture of more brain images can be dealt with, and in addition, the deep convolutional neural network is adopted, so that the image processing result is more accurate.

The invention provides a multi-mode automatic ventricular segmentation system and a use method thereof. The method comprises the following steps of collecting a manually segmented thick layer scanningdata set D1 and an unsegmented thin layer scanning data set D2; importing a pre-training model to construct an encoder ER, constructing a decoder DR through a sub-pixel convolution layer, and constructing a multi-modal ventricular segmentation model M in combination with the encoder ER and the decoder DR; generating a supervision signal S by using segmented information in the thick-layer scanningdata set D1; taking the thick-layer scanning data set D1 and the thin-layer scanning data set D2 as input, extracting a feature F, and inputting the feature F and a supervision signal S into a decoder DR; combining a loss function L1 generated by the thick-layer scanning data set D1 and a loss function L2 generated by the thin-layer scanning data set D2 to obtain a loss function L of the ventricular segmentation model M; continuously training and optimizing the ventricular segmentation model M according to the loss function L; and using the trained ventricular segmentation model M to automatically segment the brain images of different multi-modal scanning methods.

The invention relates to the technical field of ventricular drainage devices, and discloses a ventricular device. The device comprises a drainage tube, a drainage bag and a controller. The drainage end of the drainage tube is placed in the cerebral ventricle, the other end of the drainage tube is connected to the drainage bag, the drainage tube is provided with an electromagnetic pinch valve and afirst pressure sensor, the first pressure sensor and the electromagnetic pinch valve are connected to the controller, the controller is connected with a prompt device and a control input device, thecontroller is also connected with an intracranial pressure monitoring device, and the intracranial pressure monitoring device comprises an intracranial pressure monitoring probe extending into the brain. According to the ventricular drainage device of the present invention, the adjustment and control of drainage can be realized according to the set pressure value, the drainage is not affected by the posture of patients, the medical staff can be reminded in time when the drainage tube is not smooth, the use safety is ensured, the intracranial pressure of patients can be more accurately controlled, and the device is conducive to the improvement of the prognosis of patients.

The invention discloses application of N-acetylserotonin in preparation of a drug for treating intraventricular hemorrhage and belongs to the technical field of biomedicines. The invention discloses and proves that the N-acetylserotonin can relieve cerebral edema and blood brain barrier destruction caused by the intraventricular hemorrhage; it is discovered that the N-acetylserotonin has an improvement effect on sports and learning memory disorder induced by the intraventricular hemorrhage; it is disclosed that a protection effect of the N-acetylserotonin is related to relief of oxidative stress, inhibition of ferroptosis and improvement on synaptic plasticity; and in addition, in a primary cortex neuron haemorrhage cell model, it is proven that the NAS can obviously inhibit neuron death induced by Hemin and relieve axon injury. According to the application, a scientific basis is provided for utilizing the N-acetylserotonin to treat the intraventricular hemorrhage as a novel drug.

The invention relates to an adjustable external ventricular drainage device fixing frame. The fixing frame comprises a fixed box, a height adjusting rod and an angle adjusting rod, wherein a groove isformed in one side of the fixed box; the locking screw penetrates through the fixed box and extends into the groove; the locking screw is in threaded fit with the fixed box; a gear cavity is furtherformed in the fixed box; gear is arranged in the gear cavity, the gear is connected with a height adjusting knob arranged outside the fixed box through a rotating shaft; a rack is arranged on one sideof the height adjusting rod; the height adjusting rod penetrates through the fixing box and a rack on the height adjusting rod to be matched with the gear, a rotating shaft is arranged at one end ofthe height adjusting rod and penetrates through the head of the height adjusting rod, an angle adjusting knob is arranged at one end of the rotating shaft, the other end of the rotating shaft is connected with the end of the angle adjusting rod, and a hook is arranged on the angle adjusting rod. The fixing device is used for fixing and supporting the external ventricular drainage tube and the drainage device, the height and angle can be adjusted at will, it can be guaranteed that the relative position of the drainage device and the head is fixed, and operation is convenient.

The invention provides a method, a device and equipment for determining a bleeding area based on a brain image, and a medium. The method comprises the following steps: determining a brain tissue area of each image in a brain CT image sequence; according to each brain tissue area, determining a ventricular edge corresponding to each brain tissue area; performing Hough transform straight line detection on each ventricular edge to obtain a target line segment of each ventricular edge; and determining a target area according to the target line segment of each ventricle edge, performing parabola fitting on pixel points of the target area to obtain a fitting result, and determining whether a bleeding area exists in the target area or not according to the fitting result. According to the method, the bleeding area is automatically determined based on the brain CT image, manual participation is not needed, the recognition speed is high, and the accuracy rate is high.

A limiting buffer assembly is installed on the top face of a bottom plate, the bottom end of an internal thread supporting pipe is movably sleeved with a supporting plate, an edge spring is welded to the middle of the top face of an arc-shaped sliding block, an annular bottom groove is formed in the position, corresponding to the end of a rotating plate, of a sleeve, and threading rings are evenly welded to the middle of an S-shaped spring plate. A drainage bottle limiting assembly is arranged between the rotating plate and the supporting plate, the ejector rod is connected with a drainage tube protection assembly, and a disinfection anti-disengaging assembly is installed at one end of a protection tube. A drainage bottle is clamped and fixed through the rotating plate after being placed on the top face of the supporting plate, and the drainage tube is guided and limited through an S-shaped spring plate and a threading ring; the S-shaped spring plate deforms to be matched with the bending shape change when the drainage tube is pulled, the drainage tube is prevented from being bent and blocked, the supporting plate slides along the internal thread supporting tube for buffering, the influence of the fixing device on the position, connected with the human body, of the drainage tube is reduced, and therefore the device is more comfortable to use and better in safety.

The invention discloses a CTP image-based infarction false positive filtering method. The infarct false positive filtering method comprises the following steps: S1, segmenting a complete ventricle area in a brain tissue CTP image; S2, obtaining a brain sulcus area threshold according to the complete ventricle area threshold, and screening out a complete brain sulcus area; and S3, filtering the ventricle area and the cerebral sulcus area as false positive filtering areas. The complete ventricular region in the CTP image is firstly segmented, then the threshold value of the cerebral sulcus area is obtained according to the threshold value of the ventricle area, then the complete cerebral sulcus area is screened out, and the ventricular region and the cerebral sulcus area are used as false positive filtering regions for filtering, so that false positive probability is reduced, and diagnosis accuracy is improved.

An implantable intracranial pulse pressure modulator for treating hydrocephalus in patients of all ages is disclosed as well as a system and method for use of the same. In one embodiment of the implantable intracranial pulse pressure modulator, two one-way valves are interposed in parallel, opposing orientations between a vestibule and a chamber. One of the one-way valves, in response to systole, provides fluid communication from the vestibule to the chamber such that a small aliquot of cerebrospinal fluid (CSF) is displaced from a cerebral ventricle into a ventricular catheter, thereby reducing intraventricular systolic pressure. The other one-way valve, in response to diastole, provides fluid communication from the chamber to the vestibule such that the same volume of CSF is reintroduced into a cerebral ventricle, thereby increasing intraventricular diastolic pressure. Together, both processes work synergistically to reduce intraventricular pulse pressure in order to treat hydrocephalus.

The present invention relates to a pharmaceutical composition for treating cerebrovascular diseases including stem cell-derived exosomes as an active ingredient. The stem cell-derived exosomes according to the present invention have superior nerve cell protective effects, such as inhibition of cerebral ventricular distention, reduction of hydrocephalus, and inhibition of nerve cell death and cellular inflammation in an intraventricular hemorrhage (IVH) animal model, and thus, can be useful in treating cerebrovascular diseases including intraventricular hemorrhage, etc.

The invention discloses ventricular drainage tube clamping equipment for neurosurgery and a use method thereof, and particularly relates to the technical field of ventricular drainage tube clamping, the ventricular drainage tube clamping equipment comprises a clamping shell, two symmetrically arranged connecting blocks are connected to the bottom end of the clamping shell, and a micro-control mechanism is arranged at the top end of each connecting block. A micro-control mechanism is adopted to start the output end of a first micro gear motor to rotate forwards, a connecting sleeve rod can drive a drainage tube in an arc-shaped buckling plate to be adjusted on the left side and the first micro gear motor to rotate backwards, and therefore the four-axis multi-angle driving effect can be achieved, even when the hands are sore, fine adjustment operation can be achieved by controlling and adjusting the position of the drainage tube, the situation that the position of the drainage tube is affected by large adjustment amplitude is avoided, meanwhile, wrist force is not needed in the adjustment process, the deflection angle is small, the drainage tube is prevented from deviating to affect the drainage effect, and operation is more convenient, time-saving and labor-saving.

An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male and female fasteners, a coupler, a driveline assembly, and a co-pulsatile driver. Forward and backward flow communication between the blood pump and the heart chamber is accomplished using the present flow cannula invention which is anastomosed to the heart chamber in a sutureless manner. When providing circulatory support, the co-pulsatile driver ejects blood out of the blood pump during systolic ventricular contraction and fills the blood pump with blood during diastolic ventricular relaxation.

The invention discloses a training method and device for improving a ventricular segmentation model, electronic equipment and a medium. The method comprises the following steps: acquiring a normal brain sample image; acquiring a standard brain image and a ventricular label corresponding to the standard brain image, wherein the standard brain image is a human brain three-dimensional image in a preset standard space, and the ventricular label is used for marking the position of a ventricular area; calculating a transformation relation between the normal brain sample image and the standard brain image; converting the ventricular tag of the standard brain image into a space coordinate system corresponding to the normal brain sample image based on the transformation relation to obtain the ventricular tag of the normal brain sample image; performing three-dimensional image deformation processing on the plurality of normal brain sample images and the ventricular labels of the normal brain sample images to obtain a plurality of ventricular deformation sample images and ventricular labels of the ventricular deformation sample images; and training the network model by using a sample data set to obtain a ventricular segmentation model, the sample data set comprising a plurality of ventricular deformation sample images and ventricular tags of the plurality of ventricular deformation sample images.

A ventricle drainage tube comprises a catheter and a drainage bag, a flow limiting valve is additionally inserted between the catheter and the drainage bag. The flow limiting valve comprises a valve cylinder, a narrow channel cover, which is in thread connection with one end of the valve cylinder and allows a liquid to pass and enter the valve cylinder, and a buffer cylinder, which is in thread connection with the other end of the valve cylinder and is used for discharging the liquid, and a buffer partition plate that extends from the inner wall to the cylinder center is arranged in the buffer cylinder; a supporting seat with a plurality of through holes is arranged on the inner side of one side, close to the buffer cylinder, of the valve cylinder, a supporting rod is arranged on the supporting seat, a spring is sleeved on the supporting rod, and the tail end of a spring is ejected into the tail end of a valve pin; and the valve pin abuts against the opening edge of a narrow channel opening, communicated into the valve cylinder, of the narrow channel cover. The height limitation of a traditional drainage tube is eliminated, and the intracranial hydrops pressure difference between the drainage tube and a patient can be automatically balanced and adjusted through a flow limiting valve. Compared with other equipment, the cost is low, disposable use can be realized, and safety and sanitation are realized. In addition, the flow velocity can be inhibited in a certain procedure in the early drainage stage through the buffer cylinder, and too fast drainage is prevented.

The invention discloses a drug injection device which comprises a catheter component, an injection head and a handle. The catheter component comprises an outer sleeve, a drug feeding pipe and a filler, the inner side of the outer sleeve is filled with the filler, a catheter channel is formed in the middle of the filler, the drug feeding pipe is connected on the inner side of the catheter channel in a sleeving manner and slidably connected with the inner wall of the catheter channel, one end of the catheter component is connected with the injection head, and the other end of the catheter component is connected with the handle. According to the drug injection device, when a drug is injected into a cerebral ventricle, an injection area of the drug is widened, so that the drug is more uniformly diffused, treatment of a patient can be facilitated, biopsies of the cerebral ventricle of the patient can be achieved, the patient is conveniently treated by medical staff, and the pain of the patient is prevented when biopsy is implemented for the patient again.

The invention discloses a ventricular puncture model and belongs to the field of medical teaching instruments. The ventricular puncture model is characterized by comprising a skull model, a brain model and a thrombus model; a skull is divided into an upper skull structure and a lower skull structure from the temporal part; a detachable component is arranged between the upper skull structure and the lower skull structure; holes are formed in the left and right sides of the top of the upper skull structure of the skull; a brain model comprises left and right ventricle models and a third ventricle model; the third ventricle model is arranged in the left ventricle model and the right ventricle model; the surface of the brain model is provided with grooves; venation plexus is arranged in the brain model; a specific hydrogel material is adopted, so that the touch feeling is simulated; key brain structures such as left and right ventricles and a third ventricle in an intracranial hyperbaric state are included, and important brain characteristics such as cerebral gullet, venation plexus and the like are contained; and through the design of the auxiliary fixing device and the cerebral groove position, the model can be repeatedly used for brain puncture operations such as third ventricular fistulization and cerebral hematoma aspiration, and the teaching experiment effect can be greatly improved.

The invention belongs to the technical field of external ventricular drainage, and particularly provides an improved external ventricular drainage device. The improved external ventricular drainage device comprises a handle, wherein a limit block is fixedly connected with one end of the handle, a puncture needle is fixedly connected with one end of the limit block, a connecting block is clamped with the surface of the limit block, a clamp block is fixedly connected with one end of the connecting block, a joint is in sleeve joint with the surface of the connecting block, and a drainage needle is fixedly connected with one end of the joint. According to the improved external ventricular drainage device, the handle, the limit block, the puncture needle, the connecting block, the clamp block,the joint, the drainage needle, a groove, clamp grooves, a first round hole, a limit groove and a second round hole are arranged, by cooperation of the components in actual application, the force bearing area of the handle in a puncturing process is increased, so that the puncturing process is faster and more convenient, meanwhile, under the actions of the limit groove and a limit plate, the handle can rotate the joint and the drainage needle, therefore, the opening direction of the drainage needle is adjusted, and the drainage position is more accurate.

Systems, devices, user interfaces, and methods for managing patient conditions. A system for monitoring and / or managing a patient suffering from a brain condition may include a controller obtaining and / or storing data related to one or more monitored patient parameters contributing to the brain condition of the patient and displaying values of the one or more monitored patient parameters in trend lines over time on a user interface. The displayed trend lines may represent values of ventricular CSF volume, values of IVH volume, total ventricular volume in the brain, and / or values of other suitable parameters. The data related to the one or more monitored patient parameters may include images of the patient's brain and / or data derived from images of the patient's brain and / or suitable patient data.

The invention relates to the technical field of surgical instruments, in particular to a ventricular drainage device fixing rod for neurosurgery, which comprises a fixing support, a vertical rod is fixedly connected to the fixing support, a fixing base is slidably connected to the vertical rod, the fixing base slides along the height direction of the vertical rod, and a fixing assembly for fixing a drainage bag is connected to the fixing base. The vertical rod is slidably connected with a tube clamp capable of clamping a drainage tube, the vertical rod is connected with a control system, and the control system comprises a flow velocity detection module, a flow velocity comparison module and an alarm module.

The ventricular drainage tube comprises a drainage tube body and a guide wire, the drainage tube body comprises a drainage cavity at the front end and a flow guide cavity at the rear end, the drainage cavity is made of elastic materials, and the guide wire penetrates through the flow guide cavity to move relatively in the drainage cavity and moves out of the drainage cavity. The drainage cavity is self-recovered to be of an arc-shaped bent structure under the action of elastic force. The invention further provides a using method of the ventricular drainage tube. According to the ventricular drainage tube, the drainage cavity with the elastic memory function is adopted, the drainage cavity is in an arc-shaped bent state during drainage so that the contact area of the drainage cavity in an intracranial drainage area can be increased, sufficient drainage can be achieved, and craniocerebral injury caused by the fact that the drainage cavity is inserted too long can be avoided; when the drainage cavity is removed, the drainage cavity is in a linear state under the action of the guide wire so that the drainage cavity can be smoothly detached, and the drainage tube is simple in design structure, convenient to operate, not prone to blockage and sufficient in drainage.

The invention provides an anti-gravity device which is applied to the human body and resists excessive shunting or insufficient shunting caused by posture change after ventriculo-peritonal shunt operations. The device is mainly applied to ventriculoperitoneal shunting treatment of hydrocephalus of the cerebral neurosurgical department. The device is characterized by having the function of resisting positional hydrostatic pressure generated due to the posture change of the human body.

Described herein is the use of CSF, more particularly external CSF or CSF-like compositions for the treatment and prevention of different diseases. More particularly, the application provides for the administration of CSF to the intrathecal space or the cerebral ventricles of a patient to increase intracranial pressure and / or CSF flow.

The invention discloses a ventricle puncture guiding device, which belongs to the technical field of medical devices and can solve the problems of complicated, time-consuming, high cost, strong subjectivity, and high puncture difficulty in the prior ventricle puncture. The ventricle puncture guiding device includes: a first positioning structure; it includes a first positioning plate, the first positioning plate has a concave first arc edge; the first arc edge is used to fit the first line on the surface of the skull; The second positioning structure; it includes a second positioning plate and a plurality of third positioning plates; the plurality of third positioning plates are sequentially movably connected head to tail to form a fitting, and the second positioning plate and the plurality of third positioning plates are located on the same plane; The side edges in the length direction of the fitting are used to fit the second line on the surface of the skull; the first line and the second line are perpendicular or intersect; the second positioning plate includes a first side edge close to the first positioning plate, and the first side edge It is used to be in close contact with the surface of the first positioning plate to form an angle line. The invention is used for ventricle puncture.

The ventricular synchronous drainage device comprises a base, a control box is fixedly installed at the upper end of the base, universal wheels are fixedly installed at the lower end of the base, a connecting port is fixedly formed in the right end of the control box, and a ring sleeve is fixedly installed in the middle of the upper end of the control box; a supporting column is fixedly installed at the upper end of the interior of the ring sleeve, a telescopic column is movably installed at the upper end of the supporting column, a display screen is fixedly installed at the outer end of the supporting column, an operation panel is fixedly installed at the lower end of the display screen, and a top plate is movably installed at the upper end of the telescopic column. According to the ventricular synchronous drainage device based on grating sensing, a synchronous adjustment mode is adopted, when the head of a patient moves, the connection port is connected with an external sensor to enable the control box to enable the drainage bottle to ascend synchronously, and the situation that ventricular effusion of the patient flows back to cause secondary injury due to untimely synchronization of the drainage bottle is avoided; and the protection effect of the device is effectively improved.

The invention discloses a liquid storage bag type wireless intracranial pressure monitoring system, and particularly relates to the field of medical instruments. The liquid storage bag type wireless intracranial pressure monitoring system comprises an intracranial monitoring end and an extracranial monitoring end, the intracranial monitoring end comprises a liquid storage bag, a hydraulic sensor is installed on the inner side wall of the liquid storage bag, an NFC integrated chip is fixedly installed on one side of the hydraulic sensor, and an NFC coil is embedded in the liquid storage bag, the extra-cranial monitoring end comprises an intracranial pressure monitor, and the intracranial pressure monitor is connected with an NFC reader through a data line. Intracranial pressure monitoring and the liquid storage bag for ventricular drainage are combined together, the hydraulic sensor is arranged in the liquid storage bag, the liquid storage bag is buried under the skin of a patient, no external line is arranged, and intracranial infection caused by intracranial and external communication in a traditional intracranial pressure monitoring tube implantation operation is avoided; the risk that pipelines fall off or lines are broken in the monitoring and carrying process of a patient is avoided, the intracranial pressure monitoring time can be prolonged, and the purpose that one object has multiple purposes can be achieved.