13 results about "Cerebral ventricular" patented technology

This invention belongs to the field of animal model technology, specifically disclosing a method for constructing a primary ciliary motor disorder hydrocephalus model, comprising the following steps: screening benzimidazole as a modeling agent; administering benzimidazole solution to experimental animals and setting up a blank control group; conducting experimental verification through pathological morphology and behavioral methods; if the experimental animals show significant ventricular enlargement and significant decrease in motor ability, the primary ciliary motor disorder hydrocephalus model is successfully constructed. This invention employs the above-mentioned novel method for constructing a primary ciliary motor disorder hydrocephalus model. The constructed hydrocephalus model exhibits good stability and repeatability, is objective and simple, and is highly operable, reducing other possible interfering factors. It provides a necessary experimental foundation for studying the mechanism of primary ciliary motor disorder hydrocephalus and developing treatment methods.

The utility model provides a laser-assisted ventricular puncture device. The laser-assisted ventricular puncture device comprises a guide core part and a laser transmitter, the guide core part comprises a guide core and a handheld part arranged at the tail end of the guide core, the handheld part is provided with two fixing frames, the two fixing frames are perpendicular to each other on a projection plane perpendicular to the guide core, and the intersection point is coaxial with the guide core; the number of the laser emitters is two, and the two laser emitters are fixed to the two fixing frames respectively. Accurate and visual alignment can be realized; deviation caused by visual errors is avoided.

The invention relates to the technical field of tearable tube sheaths, in particular to a tearable shunt tube sheath for ventricular jugular vein shunt, which comprises a catheter sheath and a mounting base inserted into the upper end of the catheter sheath, the catheter sheath is detachably connected with the mounting base, and an expansion catheter is fixedly mounted at the upper end of the mounting base. A hemostasis valve is mounted at the lower end of the mounting base; mechanical locking and pressing force adjustment are conducted on the two tearable tubes through the connecting piece, the situation that a traditional tube sheath needs to be torn open is avoided by pulling the pulling-out unit, the connecting piece is stably and linearly pulled out as a whole, and in the process, instant traction force and vibration generated due to material tearing and buckle separation when a sheath tube is torn in a traditional mode are completely avoided; the risk of tiny displacement of the tip of the accurately positioned shunt tube caused by sheath tube removal operation is eliminated, the shunt tube is always stabilized at the optimal position in the middle of the right atrium, and the operation success rate is increased.

The invention relates to the technical field of medical image processing and artificial intelligence, and discloses a brain iron deposition spatial distribution pattern intelligent identification and typing method and system, and the method comprises the steps: carrying out the spatial standardization and brain region segmentation of a whole-brain QSM image; generating a spatial distribution feature vector through a multi-scale spatial attention feature extraction network; an iron deposition mode is divided into a cortex type, a deep nuclei type, a ventricular surrounding type and a diffuse type by adopting a fuzzy clustering algorithm of spatial neighborhood constraint; establishing a mapping relation between the iron deposition mode and the vascular cognitive impairment etiology subtype; according to the method, automatic recognition and typing of the brain iron deposition space distribution mode are achieved, the mode recognition accuracy rate reaches 85% or above, and an auxiliary diagnosis basis is provided for vascular cognitive impairment pathogenesis typing.

The invention discloses an anti-bending fixing device of a drainage catheter for external ventricular drainage, relates to the field of cerebral drainage auxiliary instruments, and solves the problems that the drainage catheter is easy to bend due to the subscalp hidden trend, the drainage is unsmooth, the intracranial pressure measurement is inaccurate, and the existing fixing mode needs frequent human intervention. The device comprises a contact piece surrounding a drainage catheter, the contact piece is provided with a first adhesion layer and an inner side limiting protrusion, and the outer side is rotationally connected with a locking piece with a first connecting hole; the anti-bending supporting plate with the bending angle of 90-180 degrees is connected with the locking piece through a pin, and the auxiliary supporting plate is assembled to be matched with the trend of the guide pipe. The locking piece is connected with the telescopic connecting frame and the mounting frame, a reverse control shaft in the mounting frame is connected with two sliding frames, and the sliding frames are provided with supporting pieces with flexible bags and second adhesion layers. The device achieves accurate bending prevention and stable supporting, manual operation is reduced, drainage and pressure measurement accuracy is guaranteed, and adaptability is high.

The invention discloses an external ventricular drainage regulation and control device, and relates to the technical field of medical health. The external ventricular drainage operation through hole is formed in the top surface of the helmet; the drainage tube accommodating groove is embedded in the top surface of the helmet; the drainage bag accommodating groove is embedded in the top surface of the helmet; the flow velocity sensor is used for collecting the flow velocity of the drainage tube and the change condition of the flow velocity; a flow rate adjusting device; and the drainage control module is in signal connection with the flow velocity sensor and the transmission motor. The drainage device is fixed on the basis of a hardware structure, the flow speed regulation and control component is matched, drainage work is monitored in real time, automatic adjustment is carried out, and it is effectively guaranteed that the drainage work is safely and reliably carried out.

The WNT-ACTIVATED ADIPOSE-DERIVED STEM CELL APPARATUSES, METHODS AND SYSTEMS (hereinafter “WAADSC”) disclosed herein in various embodiments provide for production of an isolated and enriched population of mesenchymal stem cells that have an active Wnt signaling demonstrated by the elevated expression of Lgr5 marker and / or Nestin in more than 50% of the population. Such an autologous cell population may, in embodiments, be injected into cerebral ventricles of patients with neurodegenerative diseases to yield therapeutic results, such as halting the progression of certain conditions and / or ameliorating specific symptoms thereof.

The utility model relates to medical instrument technical field especially a ventricular peritoneal shunt pass bar. The utility model discloses pass bar subassembly, handle, guide piece and shunt tube fixed subassembly, pass bar subassembly includes the pass bar body of being placed in the patient's skin and the installation sleeve of being fixed in the pass bar body front end end portion, shunt tube fixed subassembly includes the installation post of being detachably installed in the inside of installation sleeve, the disc that is fixed in the installation post front end end face and with installation sleeve front end end face abuts and the plug rod of rotating being arranged in the disc front disc surface middle part and being inserted in the shunt tube spout, the guide piece detachably sets up in the installation sleeve outside, the handle is fixed in the pass bar body rear end. The device can reduce the external diameter of pass bar subassembly whole under the condition of keeping the shunt tube diameter invariable to reduce the injury to the child when puncturing.

The present application relates to the technical field of medical image processing and artificial intelligence, and discloses a brain iron deposition spatial distribution pattern intelligent recognition and typing method and system, which comprises: spatial standardization and brain region segmentation of whole brain QSM images; generating a spatial distribution feature vector through a multi-scale spatial attention feature extraction network; dividing the iron deposition pattern into a cortical type, a deep nuclear group type, a periventricular type and a diffuse type by using a fuzzy clustering algorithm with spatial neighborhood constraints; establishing a mapping relationship between the iron deposition pattern and the etiological subtype of vascular cognitive impairment; and evaluating the bilateral hemisphere iron deposition asymmetry, wherein the present application realizes automatic recognition and typing of the brain iron deposition spatial distribution pattern, the pattern recognition accuracy reaches more than 85%, and provides an auxiliary diagnosis basis for etiological typing of vascular cognitive impairment.

This invention relates to the field of medical device technology and discloses a fixation device for an external ventricular drainage tube and an intracranial pressure probe, including a side plate and a top plate. An adjustment assembly is provided between the side plate and the top plate, and a fixation mechanism is provided on the outer side of each side plate and the top plate. This invention secures the device to the patient's head by fastening the fixation sleeve formed by the side plate and the top plate to the outside of the patient's head. Then, the first and second fixation straps are pulled and secured using the round and barbed surfaces of the Velcro. The fixation is convenient and quick. The breathable padding improves the comfort and breathability of the device after fixation, preventing discomfort or allergic reactions caused by stuffiness. Furthermore, during fixation, adjustments can be made by pulling the two sets of side plates, allowing the limiting rod to move within the cavity, thus facilitating adjustment of the fixation sleeve size. This allows for adjustment according to the patient's head size, resulting in high applicability.

Embodiments disclose systems and apparatus that provide neurogenesis activation by FUS stimulation including activating quiescent NSCs in the subventricular zone of the lateral ventricles and promoting the proliferation of NSCs and subsequent differentiation into newly regenerated neurons. Also disclosed is a conventional MRI guided tFUS system programmed for use with ultrasonic activation of NSCs. A wireless electronic driving configuration for transcranial use under MRI guidance is provided and a cylindrically distributed ultrasound transducer array design to provide increased steering range in at least two axes. A close integration of tFUS with MRI navigation, achieved by a novel wearable thin-film MRI coil array tightly integrated with the transducer array, enables full navigation performance of MRI in real time during FUS treatment.

The application discloses a ventricular drainage regulator, belongs to the field of drainage devices, and is used for ventricular drainage and comprises a liquid storage tank provided with a tank body connecting pipe, wherein the liquid storage tank is connected with a negative pressure tank provided with a main piston through a threaded structure, the main piston is connected with an auxiliary rack through a main piston rod, the auxiliary rack is in mesh transmission with a driving gear of a rack driving motor, a main cavity in the negative pressure tank is communicated with an auxiliary cavity in a negative pressure auxiliary pipe through a cavity connecting hole, an auxiliary piston is arranged in the auxiliary cavity, the auxiliary piston blocks the cavity connecting hole in an initial state, the auxiliary piston is connected with an auxiliary piston rod, the auxiliary piston rod is connected with a linkage rod, the linkage rod is connected with a linkage plate, the linkage plate is connected with the auxiliary rack, and the application can generate and fine tune a negative pressure environment through structural adjustment, can effectively guarantee the stability of the negative pressure environment, can increase and fine tune the negative pressure, has better flexibility and adaptability, and is convenient for ventricular drainage and observation of drainage volume.

An irrigation assembly for an external ventricular drainage tube (EVD) system, comprising: a collapsible upper body and a base, the irrigation assembly connected to an external ventricular drainage tube using a connector adjacent a bottom end of the irrigation assembly; the connector intersects with the collapsible upper body and / or a base, the base intersects with the connector, and wherein the irrigation assembly stores fluid in an internal fluid reservoir, and when the irrigation assembly is activated, the irrigation assembly is coupled to the connector. The collapsible upper body pushes fluid from the inner fluid reservoir to an irrigation site to perform irrigation of the external ventricular drainage tube.