35 results about "Brain condition" patented technology

A method for treating brain-related chronic pain disorders in human subjects includes assessing the brain function of a subject suffering from chronic pain, diagnosing a chronic pain-related abnormal brain condition, and mitigating the abnormal brain activity by applying an electrical stimulation signal to tissues corresponding to at least one area of abnormal brain activity.

Disclosed embodiments relate to an apparatus for detecting brain conditions. The apparatus for detecting brain conditions may include: a layer which is located adjacent to the brain of a living body; a light source which is formed on the layer and irradiates light to the brain; and an optical sensor which is formed on the layer adjacent to the light source and detects the light scattered from the brain. Since detection is possible at a location relatively adjacent to the brain, the apparatus for detecting brain conditions may improve accuracy and reliability of detection. The apparatus for detecting brain conditions may be used to detect brain conditions such as cerebral oxygenation, cerebral blood volume, cerebral blood flow, etc. or to monitor brain activities, or to diagnose and / or localize the disease foci in case of neurovascular disease such as stroke including hemorrhage or bleeding, into or around the brain or brain tumors or epilepsy, etc. Since the apparatus for detecting brain conditions has a relatively flexible structure, damage to the brain tissue may be minimized.

The present invention provides, among other things, methods and compositions for treating brain conditions. In some embodiments, the methods include administering to a subject suffering from or susceptible to a brain condition an angiotensin (1-7) peptide via either an intravenous or subcutaneous route of administration.

The present invention provides, among other things, methods and compositions for treating brain conditions. In some embodiments, the methods include administering to a subject suffering from or susceptible to a brain condition an angiotensin (1-7) peptide via either an intravenous or subcutaneous route of administration.

Systems and methods are provided for rapidly introducing treatment to patients suffering traumatic brain injuries. A wearable map of the brain electroencephalography (EEG) points is worn in a headscarf, helmet, or other headgear for providing real-time information on a wearer's brain condition. The overall system includes an application (app) or program software that may run on a tablet, portable communication device, or computing device that processes the data from the EEG sensors and interprets the data in real time. If there is an accident or other stress forces experienced by the wearer that mimics a concussion, the system initiates the real-time ejection of a cooling agent within the headgear to provide a reduction in the victim's brain temperature with the helmet cooling system. A drug intervention system and injury detection app for expedited treatment of a potential brain injury during the critical early phases of the injury is also provided.

An apparatus that supports a rehabilitation of a brain-damaged patient, including a patient condition analyzer configured to generate a patient condition scenario about a brain condition of a patient based on brain-related information of the patient, a network model determiner configured to determine a network model to be applied to the patient using the patient condition scenario, and a rehabilitation model generator configured to generate a rehabilitation model to be applied to the patient based on the determined network model.

The invention provides a hospital care system. The hospital care system comprises a plurality of acquisition devices, a transmission device and a terminal receiving device. The system has the following beneficial effects: care workers can know about conditions of patients in real time or at a preset moment comprehensively and take measures to save the patients timely in case of abnormities; due to the alarm function of the system, the timeliness and the comprehensiveness of patient condition information provided by the system are enhanced; physiological index data capable of indicating the patient condition is provided timely and comprehensively on the premise that the patients are not disturbed during rest at night, and the emotional resistance of the patients is eliminated; the labor intensity of the care workers is reduced, and the problem that fatigue is easily caused due to large average care business volume caused by a small number of care workers is solved; the medical treatment environment for the patients is improved, and the survival rate of the patients is increased in case of unexpected emergencies.

Disclosed are systems and methods for capturing a pupillary light reflex (PLR) by capturing images of a subject's pupil, for example using a smartphone, extracting image data to determine PLR and classifying the PLR to provide an analytical output, such as a diagnosis or prognosis, of a neurological or psychiatric brain condition.

The invention provides a bad learning habit reminding method and reminding device. Learning state data are counted. A statistical value which changes as learning state changes is calculated. According to the statistical value, a bad learning state judging threshold value is set. In a bad learning state, a processor triggers a reminder. The learning state comprises a head posture, an eye distance, or a brain condition. According to the invention, a statistical method is used; according to personal habits, a judgment standard with obvious individual characteristics is established; the change of usage is tracked in the course of using; constant self-adjusting is carried out to adapt to different groups and individualities; and the bad learning habit reminding method and reminding device are targeted, take a gradual approach for bad state changes, and are easy to accept.

An exemplary method of treating a chronic low back pain condition in a patient includes 1) generating, by an electroacupuncture device implanted beneath a skin surface of the patient at at least one of acupoints BL22, BL23, BL24, BL25, and BL26 within the patient, stimulation sessions at a duty cycle that is less than 0.05, wherein the duty cycle is a ratio of T3 to T4 and each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes, and 2) applying, by the electroacupuncture device, the stimulation sessions to the target tissue location in accordance with the duty cycle.

The present invention relates to methods for characterization of bacterial skin microbiota to provide diagnostic, therapeutic, and preventive measures for alleviating skin conditions. In certain embodiments, the invention relates to characterization of bacterial skin microbiota associated with psoriasis and related diagnostic, therapeutic, and preventive measures for alleviating psoriasis. These methods will be useful for detecting, diagnosing, and monitoring individuals who have or are at risk of certain skin conditions.

Described herein are methods and compositions for the treatment of skin conditions associated the dysbiosis. Further described herein is the use of metabolites for treatment of dysregulated microbiota in a subject. Such metabolites can be produced by microorganisms present in a higher abundance in the skin of healthy subjects as compared to the skin of a subject having dysbiosis of the skin. In addition, compositions and methods provided herein describe the use of metabolites as part of a combination therapy.

The present invention relates to a novel approach means of screening foot skin condition of patients at risk for foot tissue breakdown, such as persons with diabetes, through the provision of a remote screening device that can be used in telemedicine or home self-monitoring approaches. The invention would record high resolution images of the bottom of the patient's feet, without artifacts or other distortions that might arise from images taken of feet that have been compressed through standing and the like. These images could immediately be viewed by the patient and / or electronically submitted to a medical facility where clinicians could screen the images for signs of tissue breakdown.

This document provides methods and materials related to assessing brain conditions within mammals. For example, methods and materials that can be used to determine whether or not a mammal (e.g., a human) with a brain aneurysm is likely to experience brain aneurysm rupture are provided.

Methods for treating pain, inflammation, and skin conditions comprise exposing at least a portion of the body of a subject having pain, inflammation, or a skin condition to a bioelectromagnetic field having low frequency and low viscosity for a period of time sufficient to treat the pain, inflammation, or skin condition. Bioelectromagnetic fields may be generated by the interaction of an electromagnetic field generated by a device or composition with the natural electromagnetic fields produced by the body. Such generated bioelectromagnetic fields treat the pain, inflammation, and skin conditions.

An image analysis apparatus that analyzes a skin condition from a video of the face of a subject captured with an imaging part includes a tracking part configured to track the amount of changes of multiple tracking points arranged in advance in an analysis region of the face based on a change in the expression of the face included in the video, and obtain the compression ratio of the skin in the analysis region based on the amount of changes, and a skin condition analysis part configured to analyze the skin condition of the subject based on the compression ratio obtained by the tracking part.

Vascular conditions are detected non-invasively in the human body using a collection of information from small local regions of the vasculature, or from a specific signature or “BrainPulse” that can be derived from a patient's heartbeat-induced cranium movements. An array of accelerometers or other sensors are engaged against the head of a patient and skull movements, preferably under 100 Hz, are recorded. Vibration signatures of vessel structures such as branches, aneurysms, stenosis, etc. using random, periodic, band limited or transient analysis provides a library for further processing. The signature library is used to localize the origin of the recognized vascular feature, and the localized feature is presented to the physician in a clinically relevant manner.

The invention discloses a chest detection method, an electronic device and a health monitor. The health monitor can be used to detect tissue physiological data of a user's breast and detect whether the physiological state change of the user's breast conforms to a preset abnormal condition according to the tissue physiological data of the user's breast previously obtained and the tissue physiological data of the user's breast currently obtained by the health monitor; and output alarm information when the physiological state change of the user's breast conforms to the preset abnormal condition.The health monitor makes the professional detection of the user's breast simpler and more convenient. Compared with the traditional annual inspection, the invention not only avoids the problem that detection in the hospital is restricted by location and time, but also is more beneficial to the realization of long-term regular monitoring of the user's breast conditions and conducive to early discovery of breast abnormality or lesions, thereby increasing the probability of early discovery of diseases such as breast cancer.

The invention relates to an ultralow-frequency EEG (electroencephalograph) detector and an ultralow-frequency EEG detection and analysis method. The detector comprises a direct-current EEG amplifier connected with a computer, the direct-current EEG amplifier is detachably connected with multiple EEG electrodes, a control circuit board electrically connected with the EEG electrodes is arranged in the direct-current EEG amplifier, a filter unit, an operational amplifier, a digital-to-analog converter unit and an MCU or DSP unit which are electrically connected are arranged on the control circuitboard, the filter unit comprises a high-pass digital filter and a low-pass digital filter which are electrically connected, the high-pass digital filter filters low-frequency signals firstly and hasthe cut-off frequency of 1 mHz, and the low-pass digital filter filters high-frequency signals later and has the cut-off frequency of 1 Hz. The invention also relates to a detection and analysis method for acquiring and detecting EEGs by the ultralow-frequency EEG detector and then processing the EEGs. The problem of detection of ultralow-frequency EEG of 1 Hz or below is solved, accurate EEGs areobtained by processing detected EEGs, and the brain condition can be known more accurately.

This document provides methods and materials related to assessing brain conditions within mammals. For example, methods and materials that can be used to determine whether or not a mammal (e.g., a human) with a brain aneurysm is likely to experience brain aneurysm rupture are provided.

Systems and methods are provided for rapidly introducing treatment to patients suffering traumatic brain injuries. A wearable map of the brain electroencephalography (EEG) points is worn in a headscarf, helmet, or other headgear for providing real-time information on a wearer's brain condition. The overall system includes an application (app) or program software that may run on a tablet, portable communication device, or computing device that processes the data from the EEG sensors and interprets the data in real time. If there is an accident or other stress forces experienced by the wearer that mimics a concussion, the system initiates the real-time ejection of a cooling agent within the headgear to provide a reduction in the victim's brain temperature with the helmet cooling system. A drug intervention system and injury detection app for expedited treatment of a potential brain injury during the critical early phases of the injury is also provided.

Methods for treating pain, inflammation, and skin conditions comprise exposing at least a portion of the body of a subject having pain, inflammation, or a skin condition to a bioelectromagnetic field having low frequency and low voltage for a period of time sufficient to treat the pain, inflammation, or skin condition. Bioelectromagnetic fields may be generated by the interaction of an electromagnetic field generated by a device or composition with the natural electromagnetic fields produced by the body. Such generated bioelectromagnetic fields treat the pain, inflammation, and skin conditions.

A sensitive measure of brain condition simultaneously evaluates multiple measurements of water diffusion in brain tissue combined so as to correct for covariance between the different data types of the multipoint measurements and compares the multipoint measurements to a corresponding multipoint measure representing normal brain tissue to provide a distance indicating a likelihood of atypical brain conditions.

Embodiments herein include a method for detecting a brain condition in a subject. The method can include obtaining a breath sample from the subject and contacting it with a chemical sensor element, where the chemical sensor element includes a plurality of discrete graphene varactors. The method can include sensing and storing capacitance of the discrete graphene varactors to obtain a sample data set and classifying the sample data set into one or more preestablished brain condition classifications. Other embodiments are also included herein.

Systems and methods for use in identifying a brain condition of a subject are provided. In some aspects, a provided method includes constructing a classifier to identify a brain condition of a subject comprising steps of receiving image data obtained from a plurality of subjects, wherein the image data is acquired during an acquisition period following administration of at least one radioactive tracer. The method also includes defining a plurality of brain condition classes using the image data associated with one or more time frames during the acquisition period, and processing the image data to generate signatures corresponding to each of the plurality brain condition classes. The method further includes constructing the classifier using the signatures. The classifier can then be applied to determine a degree to which the subject expresses one or more disease states in order to determine a brain condition of the subject.

Provided herein are amyloid-binding assays that simulate in situ brain conditions by combining binders with various A-beta species on mammalian brain tissue. In general the amyloid-binding assays comprise the steps of (a) contacting a mammalian brain tissue sample with at least one A-beta species; (b) applying a putative binder to the brain tissue sample; and (c) determining whether the putative binder binds to the A-beta species.

This document provides methods and materials related to assessing brain conditions within mammals. For example, methods and materials that can be used to determine whether or not a mammal (e.g., a human) with a brain aneurysm is likely to experience brain aneurysm rupture are provided.

A headset, configured to be attached to a human head, includes an accelerometer providing a signal indicative of head acceleration due to blood flow through the brain. An analyzer evaluates a plurality of samples indicative of acceleration over time where each sample corresponds to the head movement resulting from a cardiac contraction. The analyzer identifies brain conditions at least partially based on a level of chaos of the plurality samples. The algorithm applied by the analyzer is partially formulated based on clinical data and examination of a plurality of subjects. In one example, the plurality of samples evaluated by the analyzer are indicative of the head accelerometer only in a single axis. In some situations, the analyzer identifies brain conditions further based on contemporaneous neurological examination of the subject.

This invention relates to a method of inhibiting neuronal cell death, including protecting neuronal cells from cell death and the effects of stress, such as high or low pH, comprising administering to the cells an effective amount of Teneurin C-terminal Associated Peptide (TCAP). The invention provides the use of TCAP to prevent and / or treat a number of brain conditions, such as hypoxia-ischemia and brain alkalosis or various brain or spinal cord injuries due to physical or physiological stresses. In one aspect the invention provides a use of TCAP to increase β-tubulin, β-actin levels in neuronal cells and / or to increase fasciculation among neuronal cells, in culture or in tissue. In another aspect, the invention provides a method of treating various pH induced neuronal conditions.

Provided herein are amyloid-binding assays that simulate in situ brain conditions by combining binders with various A-beta species on mammalian brain tissue. In general the amyloid-binding assays comprise the steps of (a) contacting a mammalian brain tissue sample with at least one A-beta species; (b) applying a putative binder to the brain tissue sample; and (c) determining whether the putative binder binds to the A-beta species.