443 results about "Mri brain" patented technology

An Accommodating Intraocular Lens (AIOL) is disclosed herein, that is comprised of a flexible optic and a flexible haptic rim that conforms to the human eye capsule. The spherical or custom shape of the optic is engineered to be maintained during accommodation through the mechanical / optic design of the implant and the interaction between the implant and the naturally occurring position and actuating forces applied through ciliary muscle / zonules / and capsule as the brain senses the need to increase the diopter change or magnification when an object of fixation approaches the eye. The axial relocation or position of the AIOL may also be further adjusted anatomically to further improve the affect needed to achieve improved accommodation. Optionally, the accommodating intraocular lens is foldable or injectable for delivery of the lens into the eye.

In Pavlovian and instrumental conditioning, rewards typically come seconds after reward-triggering actions, creating an explanatory conundrum known as the distal reward problem or the credit assignment problem. How does the brain know what firing patterns of what neurons are responsible for the reward if (1) the firing patterns are no longer there when the reward arrives and (2) most neurons and synapses are active during the waiting period to the reward? A model network and computer simulation of cortical spiking neurons with spike-timing-dependent plasticity (STDP) modulated by dopamine (DA) is disclosed to answer this question. STDP is triggered by nearly-coincident firing patterns of a presynaptic neuron and a postsynaptic neuron on a millisecond time scale, with slow kinetics of subsequent synaptic plasticity being sensitive to changes in the extracellular dopamine DA concentration during the critical period of a few seconds after the nearly-coincident firing patterns. Random neuronal firings during the waiting period leading to the reward do not affect STDP, and hence make the neural network insensitive to this ongoing random firing activity. The importance of precise firing patterns in brain dynamics and the use of a global diffusive reinforcement signal in the form of extracellular dopamine DA can selectively influence the right synapses at the right time.

A method for identifying and treating a neural pathway associated with chronic pain via nerve stimulation and brain wave monitoring of a mammalian brain includes positioning a probe to stimulate a target nerve, wherein the target nerve is suspected of being a source of chronic pain; delivering a first nerve stimulation from the probe to the target nerve, wherein the first nerve stimulation is sufficient to elicit a chronic pain response in the brain; and monitoring for evoked potential activity in the brain as a result of the first nerve stimulation. The method can also include delivering second and third nerve stimulations to confirm the correct identification of the neural pathway and to treat the chronic pain, respectively. A system and apparatus for performing a procedure to identify and treat a nerve that is the source of chronic pain are also described.

With explosive penetration of portable electronic devices (PEDs) recent focus into consumer EEG devices has been to bring advantages including localized wireless interfacing, portability, and a low-cost high-performance electronics platform to host the processing algorithms to bear. However, most development continues to focus on brain-controlled video games which are nearly identical to those created for earlier, more stationary consumer EEG devices and personal EEG is treated as of a novelty or toy. According to embodiments of the invention the inventors have established new technologies and solutions that address these limitations within the prior art and provide benefits including, but not limited to, global acquisition and storage of acquired EEG data and processed EEG data, development interfaces for expansion and re-analysis of acquired EEG data, integration to other non-EEG derived user data, and long-term user wearability.

Electrical activity of the brain (EEG) and position / motion of a body part, e.g. motion of an arm, are measured. A virtual representation of either the moving body part or the intended movement as determined from the brain activity is presented as feedback to the subject on a display which can be implemented as a head-up display. A clock module is operable to time stamp information transferred from a brain electrical activity sensing system and a position / motion detection system for joint processing. This non-invasive EEG-based brain-computer-interface is particularly useful for stroke rehabilitation.

Embodiments of the disclosed technology provide a combination electroencephalography and non-invasive stimulation devices. Upon measuring an electrical anomaly in a region of a brain, various non-invasive stimulation techniques are utilized to correct neural activity. Stimulation techniques include transcranial direct current stimulation, transcranial alternating current stimulation and transcranial random noise stimulation, low threshold transcranial magnetic stimulation and repetitive transcranial magnet stimulation. Devices of the disclosed technology may utilize visual, balance, auditory, and other stimuli to test the subject, analyze necessary brain stimulations, and administer stimulation to the brain.