294 results about "Coma" patented technology

The invention provides applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma. Experimental results indicate that levorotary oxiracetam has obvious awaking effect on coma caused by alcoholism, but dextrorotary oxiracetam basically has no effect, and the awaking effect of levorotary oxiracetam is two times of that of dextrorotary/levorotary mixed oxiracetam; levorotary oxiracetam has remarkable awaking effect on comas caused by both trauma and anesthesia.

An intraocular lens comprises optical part configured to be implanted in an eye of a subject. The intraocular lens further comprises at least one aspheric surface configured, in combination with a lens in the capsular bag of an eye, to reduce an aberration of a wavefront passing the eye. The aberrations may include astigmatism, coma, and/or spherical aberrations. An aberration of the intraocular lens may be expressed as a linear combination of Zernike polynomial terms that may include a Zernike coefficient a₁₁. The Zernike coefficient a₁₁ may be selected to reduce a spherical aberration of a wavefront passing the eye and/or to compensate for an average value resulting from a predetermined number of estimations of the Zernike coefficient a₁₁ in a population of corneas and capsular bag lenses.

Embodiments of the present invention combine static analysis, source code instrumentation and feedback-guided fuzz testing to automatically detect resource exhaustion denial of service attacks in software and generate inputs of coma for vulnerable code segments. The static analysis of the code highlights portions that are potentially vulnerable, such as loops and recursions whose exit conditions are dependent on user input. The code segments are dynamically instrumented to provide a feedback value at the end of each execution. Evolutionary techniques are then employed to search among the possible inputs to find inputs that maximize the feedback score.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia. Described are methods and devices to treat coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect symptoms of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia.

Intraocular lenses (IOLs) and related methods. One embodiment provides an IOL which includes a lens optic and a pair of haptics. The haptics can be coupled to the lens optic and can cause compression of the lens optic when the IOL is fixated in an eye. The lens optic can have a compressed geometry, an uncompressed geometry including an aberration, and a desired geometry. The compressed geometry can be the desired geometry. The aberration can be astigmatism, coma, or spherical aberration. For instance, the aberration can be astigmatism of about 0.17 D at the spectacle plane and of about 0.25 D at the intraocular lens plane. Moreover, the haptics can define a first axis between the haptics; the lens optic can define a second axis perpendicular to the first axis; and the uncompressed geometry can differ from the compressed geometry in the vicinity of the second axis.

Disclosed are methods and systems and methods for neuromodulation of the Reticular Activating System using ultrasound to produce acute effects or Long-Term Potentiation (LTP) or Long-Term Depression (LTD). Included is control of direction of the energy emission, intensity, pulse duration, frequency, and phase/intensity relationships to targeting and accomplishing up-regulation and/or down-regulation. The invention can be applied for a variety of clinical purposes such as reversibly putting a patient to sleep or waking them up (for example, for the purpose of anesthesia) or reversibly putting a patient into a coma (for example for the purpose of protecting or rehabilitating the brain of the patient after a stroke or head injury).

The present invention relates generally to a diagnostic device including a prognostic assay for parameters which are indicative of a condition or event associated with the systemic vasculature. More particularly, the present invention provides an assay to detect parameters associated with a vascular disease including cardiovascular, stroke, pulmonary, renovascular, cerebrovascular, thrombotic or generalized arterial or venous condition or event including acute coronary syndrome such as but not limited to acute myocardial infarction, heart failure, atheromoma or a thrombotic condition. The identification of these parameters or more particularly a pattern of parameters enables the diagnosis of a condition or event or the determination of the risk of development of a condition or event associated to the systemic vasculature. Still more particularly, the present invention is directed to a diagnostic device comprising a set of members wherein one or more of said members has or have specific or generic binding partners in a biological sample from an animal including human subject wherein the pattern of binding of the members to the binding partners is indicative, predictive or otherwise associated with a likelihood of a condition or event within the systemic vasculature. The absence of detection of specific or generic binding partners is also of indicative or predictive value. This is particularly important in cases where patients are unable to communicate advice to a physician on their own condition, such as during surgery or for patients in a coma. It is also useful in determining the risk of a vascular disease including cardiovascular, stroke, pulmonary, renovascular, cerebrovascular, thrombotic or generalized arterial or venous conditions or events in a healthy subject or a subject entering into an exposure to risk such as surgery or chemotherapy. The present invention is useful inter alia for the identification and/or quantitation of biochemical markers of conditions or events in the systemic vasculature such as heart disease, heart disorders, infections of the heart, stroke and thrombosis as well as the determination of a risk of development of these conditions including the absence of disorders or absence of risk of the development of a disorder. The assessment of such conditions may be made in a clinical setting, as part of triage, as part of a routine testing protocol and/or as a laboratory procedure.

A method of identifying a site of injury in a pediatric patient with brain injury is provided which comprises obtaining an electroencephalogram signal on the patient. The identification of phase synchrony within the signal is indicative of the site of brain injury. Electroencephalogram signals may also be used to determine prognosis of a pediatric patient in a coma in which an increase in the temporal variability of phase synchronized EEG signals over time is indicative of an improvement in the patient.

Provided is an optical information recording and reproducing apparatus including a light beam expander for correcting spherical aberration caused when a plurality of recording layers of an optical disc are brought into focus by changing a divergent angle or a convergent angle of light entering an objective lens, and coma aberration correcting means for correcting coma aberration caused by tilt of the optical disc. When the coma aberration correcting means is driven, the value of a drive signal is varied according to a target recording layer of the optical disc. As a result, even when a transmission layer thickness varies in a multilayer recording medium, coma aberration does not remain in any of the recording layers.

The invention discloses a novel traditional Chinese medicine composite for treating coma and heart syncope symptoms and a preparation method thereof. The traditional Chinese medicine composite mainly comprises the following raw material medicines: styrax, benzoin, holy basil, rhizoma acori graminei, toad venom, tambac, santalwood, rosa banksiae, nutgrass flatsedge, toosendan fruit, radix aristolochiae, common fibraurea, macrostem onion, fructus citri sarcodactylis, citron, aspongopus, lotus node, madder, dalbergia wood, plant soot, rhizoma ligustici wallichii, corydalis tuber, turmeric, curcuma, mastic, myrrh, radix salviae miltiorrhizae, peach kernel, safflower, radix notoginseng, ground beetle, stiff silkworm, logwood, draconis sanguis, catechu, rhizoma sparganii, rhizoma zedoariae, pangolin scales, spatholobus stem, motherwort, angelica, rhizoma atractylodis, radix puerariae, angelica root, sibirian button bur, magnolia flower, purple common perilla, chrysanthemum, baikal skullcap root and coptis root. The traditional Chinese medicine composite can be prepared into any common oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can obviously improve diseases which are caused by the inverse disorder of the functional activities of qi, fluctuation warp and non-smooth qi of yin and yang and represent coma, delirium, exanimation and asphyxia as main symptoms or are accompanied with the symptoms of asphyxia and coldness of limbs, dottiness and the like, and has definite clinical curative effect, obvious curative effect and quick acting. Because the traditional Chinese medicine composite basically adopts medicine-food homologous medicines specified by the national dispensatory for combination, the traditional Chinese medicine composite has the advantages of low expense, no toxic or side effect basically and the like.

The invention relates to the determination of higher-order aberrations of an optical element over an optical zone that is larger than the typically limited measured zone over which the aberrations are measured. This is accomplished by apparatus, systems, and methods in which, preferably, the Zernike data from an aberration measurement is fit to a conic function. The conic function smoothly and continuously increases or decreases between the measured zone and the optical zone allowing the extrapolated data to accurately determine the aberrations over the optical zone. According to the invention, a plurality of independent conic plus piston sections that vary azimuthally can very accurately describe a wavefront aberration composed of defocus, astigmatism, spherical aberration, secondary astigmatism, and tetrafoil. The description of primary coma and trefoil will not be as good because they vary with the 3<rd >order of the radial component. However, the description error is relatively small. A tilt term can be added to account for the tilt component of the coma and trefoil terms.

The invention discloses an assessment method of auxiliary CRS-R scale auditory shock based on a brain-computer interface. The assessment method comprises following steps of: 1) selecting simulation, arranging and designing an experimental paradigm; 2), collecting signals; 3) performing data processing; 4) counting inspecting evaluation standards. The assessment method of auxiliary CRS-R scale auditory shock based on the brain-computer interface has following beneficial effects: based on an auditory extraneous experimental paradigm, mismatch negative waves MMN and P300, peculiar to human race, are induced; in combination with an auditory shock assessment method of a coma recovery scale CRS-R, scores of CRS-R auditory shock items are accessed by adoption of the brain-computer interface and a peak detection algorithm; and therefore, the method can not only be effectively used for assessment diagnoses of the coma recovery scale, tracking of recovery effect and selections of a prognosis treatment scheme but also provide scientific and objective detection data to the conventional scale diagnoses in order to ensure authenticity and effectiveness of detection results..

The invention provides a lower jaw supporter, which solves the problem that can not be solved in the prior art; the problem is upper airway obstruction (snoring) of non-trachea cannula general anesthesia patients and unconscious patients including patients of coma, alcoholic intoxication, toxicosis and the like. The technique proposal is that the lower jaw supporter comprises a tie plate and movable supports which are arranged at the left and the right sides of the tie plate; and the upper end of the movable support is provided with a lower jaw angle fixed disk which is adaptive to the shape of lower jaw angle. The left and right positions and the height of the movable support can be adjusted. The lower jaw supporter completely relieves hands of anaesthetists or nurses who need to use hands to support lower jaws for a long time, and provides a device specially used for supporting the lower jaw loose of general anesthesia non-trachea cannula patients; and the device mainly prevents or avoids the upper airway obstruction of the patients caused by the wallowing of tongues so as to disarm the risks of chronic oxygen deficiency of body and accumulation of carbon dioxygen caused by that the upper airways of the patients are blocked or stopped.

The invention provides a method and device for evaluating the coma degree. The method comprises: electroencephalogram data of a patient is acquired; the electroencephalogram data is pretreated, and purified electroencephalogram signals are obtained; according to the purified electroencephalogram signals, the coma degree of the patient is evaluated. According to the method, the coma degree of the patient is automatically evaluated according to the purified electroencephalogram signals of the coma patient, manual intervention in the evaluating process of the coma degree is lowered, the influence of subjective factors of medical personnel on the evaluating process is avoided, man-made erroneous judgment is avoided, the evaluating error is reduced, and the evaluating accuracy is improved. Sample entropy is applied to evaluation of the coma degree, the sample entropy corresponding to the purified electroencephalogram signals is calculated, according to a threshold value range of the sample entropy, the coma degree is evaluated, quantification evaluation of the coma degree is achieved, and the evaluation efficiency is greatly improved. Meanwhile, according to the purified electroencephalogram signals, prognosis judgment is automatically conducted, the sample entropy is applied to the prognosis judgment of the coma patient, and the efficiency and accuracy of the prognosis judgment are improved.

The invention discloses a primotest clustered hair single cell bacterium (Comamonas testosteroni) WXZ-18 CGMCC No.1800 strain with aerobic denitrifying property and a method to denitrify the waste water; which is characterized by the following: possessing strong tolerance degree for dissolved oxygen; deacidizing nitrate and nitrite with distinctive speed under the condition of 10-98% saturated dissolved oxygen; seeding to active sludge; proceeding enriched culture; realizing the aerobic anti-nitration.

The invention relates to a method acquiring telescope primary and secondary mirror alignment error based on astigmatism decomposition. The method includes the steps of measuring four misalignment rates of a secondary mirror and the proportionality coefficient of exit pupil wavefront error astigmatism coefficient to coma coefficient, wherein the proportionality coefficient is expressed through a zernike polynomial, measuring a real-time exit pupil wavefront error, placing a misalignment rate dx and a misalignment ty of the secondary mirror in one group, placing a misalignment rate dy and a misalignment rate tx of the secondary mirror in one group, decomposing a astigmatism item Ast into Astx and Asty, constructing a relation model of the misalignment rates and the astigmatism item, solving a coupling coefficient Alpha x and a coupling coefficient Alpha y, constructing a relation model of the misalignment rates and a coma item, and solving the misalignment rates of the secondary mirror according to a constructed relation model of the misalignment rates and the wavefront error.