250 results about "Pediatric patient" patented technology

Methods of administering sotalol hydrochloride in an amount effective for treating one or more cardiovascular disease or disorder in pediatric patients are described and include IV and / or oral doses based on age-specific creatinine clearance ranges.

Various devices, systems, and methods are disclosed. The method may include determining a body surface area of a patient (who may have a body surface area of about 0.6 m2 to about 1.3 m2), selecting a blood pump from a plurality of differently sized blood pumps based on the body surface area of the patient, implanting the blood pump, and activating the blood pump to provide support to the patient. The selected blood pump may have a cannula connecting an inlet and an outlet. The cannula may have a bend and a cannula length measuring an axial length between the inlet and the outlet. The cannula length may be between about 30 mm to about 46 mm if the body surface area is less than 0.9 m2.

The invention relates to the technical field of intelligent medical treatment, in particular to a pediatric patient nursing guidance method and system based on data analysis. According to the method and the device, the short-time fluctuation and the long-term trend of the physiological characteristics of the patient can be dynamically captured by acquiring the physiological sign data in the specified time period, calculating the fluctuation condition and forming the health state fluctuation information instead of only depending on single-point measurement data, so that the change characteristics of the health state are reflected more accurately. According to the method, the physiological signs conforming to the mean value or standard deviation range are screened, the individual health baseline is established, and the deviation between the individual health baseline and the physiological signs is compared, so that health assessment can be adaptively adjusted according to the reference states of different individuals instead of unified standard assessment, and misjudgment caused by individual differences is reduced. The nursing intervention level is set based on the change trend of the physiological signs, and the nursing intensity can be flexibly adjusted through factors such as duration and frequency of the fluctuation trend, so that the nursing suggestions have higher pertinence.

The invention relates to the technical field of medical apparatus and instruments, in particular to a multi-dimensional adjustable traction device for pediatric orthopedic nursing, which comprises a bottom plate and further comprises a shaking assembly connected to the bottom plate; the bed frame is connected to the output end of the rocking assembly, an upper lying plate and a lower lying plate which can rotate are connected to the bed frame, and the same mattress is placed on the upper lying plate and the lower lying plate; and the traction mechanism comprises a fixing assembly and a traction assembly. The traction mechanism and the fixing assembly are arranged to limit the legs of a pediatric patient, injury and pain caused by leg movement of the patient are relieved when the patient is nursed, the direction of traction force is the same as the direction of a fracture line, and a good treatment effect is guaranteed; the bed frame is driven by the shaking assembly to slightly shake front and back, the mood of a child patient is pacified, the metal block which is magnetically locked is kept stable relative to the bed frame, and traction stability is kept.

The present disclosure relates to solid-state forms and corresponding pharmaceutical compositions of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, and methods of treatment, including treatment of rheumatoid arthritis and juvenile idiopathic arthritis using the same. The treatment methods generally comprise administering to a patient (e.g., a pediatric patient) a therapeutically effective amount of upadacitinib as a stable liquid pharmaceutical composition or a solid dosage form, at a dose based on patient body weight.

A system for aiding in a medical clinical trial involving one or more pediatric patients includes a patient passport, individual achievement stickers that are awarded to pediatric patients and that are placed within the patient passport, and an interactive companion toy having distinctive patterns thereon. A camera of a mobile device scans the individual achievement stickers in the patient passport and / or the distinctive patterns on the interactive companion toy, and an interactive incentivization application logic section of the mobile device unlocks and display reward content to the pediatric patient. The interactive companion toy, the mobile application, and the physical passport can be customized to match particular protocols of the clinical trial. The pediatric patient is thus incentivized to participate and continue the clinical trial. Virtual medical play associated with the clinical trial can be practiced on the interactive companion toy in an augmented reality environment. Parents are assisted through automatic text message reminders, and electronic patient-reported outcomes are collected, transmitted, processed, and summarized for visualization and insights via a cloud-based clinical trial portal.

Described herein are pediatric garments for infants and children with medical needs. The pediatric garment is designed to provide quick and easy access to the body, specifically for pediatric patients, and any medical equipment, devices, and / or attachments related to the pediatric care of the patient. The pediatric garment features may include a unique combination of openings with locations that are placed according to the medical needs of a pediatric patient.

The present disclosure relates to improved lipid emulsions for providing parenteral nutrition, including ready-to-use parenteral nutrition formulations comprising such lipid emulsions. More particularly, the present disclosure is directed to improved lipid formulations or emulsions including multi-chamber containers comprising same, wherein the lipid emulsion contains DHA, EPA, and ARA in an optimized concentration and ratio, optionally in combination with choline and defined levels of phytosterols. The present disclosure further relates to methods of avoiding and / or treating liver damage and / or inflammation, and to methods for improving fatty acid profiles in plasma and certain tissues or organs especially of pediatric patients.

Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum-based chemotherapeutics.

Provided are methods for clinical treatment of Atypical Hemolytic Uremic Syndrome (aHUS) using an anti-C5 antibody, or antigen binding fragment thereof, in pediatric patients.

Provided herein are methods of preparing an engineered heart valve for implantation into a subject in need (e.g., a pediatric patient). For example, a porcine pulmonary valve can be decellularized and then recellularized with cells from the subject. Hydrogels can be used to facilitate cell delivery and growth within the sub-endothelial layer (e.g., spongiosa) of a heart valve, which is essential for long-term success of the implantation.

The present disclosure relates to improved lipid emulsions for providing parenteral nutrition, including ready-to-use parenteral nutrition formulations comprising such lipid emulsions. More particularly, the present disclosure is directed to improved lipid formulations or emulsions including multi-chamber containers comprising same, wherein the lipid emulsion contains DHA, EPA, and ARA in an optimized concentration and ratio, optionally in combination with choline and defined levels of phytosterols. The present disclosure further relates to methods of avoiding and / or treating liver damage and / or inflammation, and to methods for improving fatty acid profiles in plasma and certain tissues or organs especially of pediatric patients.

A decision support method and system is provided for monitoring and treating pediatric obesity. Embodiments include generating obesity risk curves corresponding to obesity risk levels, for example, severe and morbid obesity risk levels. Generating obesity risk curves depends on predicting at least one health proxy such as, for example, spend data and chronic conditions. Generating severe obesity curves depends on an age-dependent multiplier. An obesity risk level is assigned to a target pediatric patient using the obesity risk curves dependent on the age-dependent multiplier. In some aspects, an intervening response is initiated based on the assigned obesity risk level.

The present invention provides methods of treating or preventing atrial fibrillation, atrial flutter, or a combination thereof comprising intravenously administering sotalol hydrochloride to a subject in need thereof. Embodiments of the present invention further provide novel methods of intravenously administering sotalol hydrochloride for example in pediatric patients. The present invention provides a novel intravenous, prophylactic, antiarrhythmic method of sotalol administration.

Provided herein are methods of treating cannabinoid-induced toxicity. Further provided herein are injectable compositions for treating acute cannabinoid overdose, poisoning, or acute cannabinoid-induced CNS depression. Further provided herein are methods of treating cannabinoid-induced toxicity in pediatric patients.

The invention belongs to the field of intelligent medical treatment, and particularly relates to a method, equipment, medium and program product for predicting RMPP based on lung microvascular changes. The method comprises the following steps: S101, acquiring a CT image of a pediatric MPP patient; s102, the CT image is extracted to obtain a quantitative PBV parameter, the quantitative PBV parameter comprises BV10%, and BV10% refers to the percentage of the blood volume in a blood vessel with the blood vessel cross section area larger than 10 mm < 2 > in the total lung blood volume; and S103, if BV10% is higher than a first threshold value, judging that the pediatric MPP patient develops into a prediction result with high RMPP risk, and otherwise, outputting a prediction result with low RMPP risk. According to the application, the prediction effect on the occurrence and development of the RMPP is found by quantitatively measuring the microvascular change in the CT, and the clinical value of early diagnosis of the RMPP is realized, so that the clinical early treatment is driven.

A method of treating cancer in a pediatric patient in need thereof comprises administering to the patient 9-ING-41 in combination with an additional therapeutic agent.

The present invention provides an extended-release capsule dosage form of metoprolol succinate in the form of coated discrete units and processes for their preparation. The present invention provides an extended-release capsule dosage form of metoprolol succinate in the form of discrete units, wherein said capsule dosage form is bioequivalent to the marketed Toprol-CL® tablet. Moreover, the extended-release capsule dosage form comprising coated discrete units can be sprinkled onto food to ease administration for patients who have difficulty swallowing tablets or capsules, e.g., paediatric patients or geriatrics.

To provide methods of providing sedation or analgesia to a pediatric patient.SOLUTION: The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More specifically, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during or after surgery.SELECTED DRAWING: Figure 1

The present disclosure is related to a device for gripping catheters that are used in interventional cardiac procedures without causing internal catheter damage. The present disclosure will allow the operator to maintain improved stability and maneuverability compared with current approaches, including, primarily, digital manipulation, which can lead to fatigue, instability and inappropriate catheter movement. Specifically in the pediatric population where small movements can lead to severe and permanent complications, the present disclosure has the potential to increase the safety profile of already high-risk interventional catheterization and electrophysiology procedures.

Compositions and methods for treating hair loss and / or nail brittleness, fragility, and pitting, particularly in pediatric patients, using topically administered JAK / STAT inhibitors and one or more penetration enhancer are described herein.

The invention relates to the technical field of virtual reality, in particular to a traditional Chinese medicine pediatric acupuncture training system combined with virtual reality guidance, which comprises a virtual behavior generation module, a feedback module, an evaluation module and a guidance module. By simulating the physiological behavior of a pediatric child patient, providing sensory feedback, quantitatively evaluating the operation technique in real time and guiding the dialectical diagnosis and treatment process, high-simulation pediatric acupuncture skill training is achieved, and the clinical pertinence of training is effectively improved.

The present invention provides a liquid composition comprising effective amount of Hydroxyurea for oral administration. The invention further discloses liquid formulation in form of ready to use oral suspension which remains stable at room temperature at the time of dispensing, storage and even after reopening of the container comprising the suspension. Also provided is a method of preparing the formulation and treating sickle cell anemia in pediatric patients.

An oral formulation of granules of an active ingredient such as gepotidacin or a pharmaceutically acceptable salt thereof that rapidly disperses in water, or an oral formulation comprising such granules. Such granules provide an oral suspension with good mouthfeel and palatability. This oral suspension is particularly useful for pediatric patient populations or patient populations with difficulty swallowing.

Compositions for intranasal delivery of benzodiazepines, such as diazepam, midazolam, and lorazepam and methods for their use to treat and prevent seizures in pediatric subjects aged 2-5, inclusive. Compositions for rapid therapeutic onset with a decreased incidence and / or severity of adverse effects after administration and methods of improving patient compliance with a prescribed treatment regimen.

The utility model provides an anti-falling device for an oxygen inhalation nasal catheter for children, and belongs to the technical field of medical equipment. Comprising an upper anti-falling belt and a pipe penetrating plate, adjusting openings are formed in the two sides of the pipe penetrating plate, and the outer wall of the upper anti-falling belt is slidably connected with the interiors of the adjusting openings. By arranging the anti-falling assembly, the oxygen inhalation nasal catheter can be prevented from being pulled and falling off easily by a child patient, the anti-falling assembly is soft and breathable through the upper anti-falling belt, the lower anti-falling belt and the breathable grooves formed in the upper anti-falling belt and the lower anti-falling belt, and the soft cotton cushion making direct contact with the cheek of the child patient is made of soft cotton materials. The soft rubber support making contact with the jaw of the pediatric patient is made of soft rubber and is in an upwards-bent-arc shape, the jaw is surrounded, the wearing comfort of the pediatric patient is improved, the upper anti-disengaging assemblies can be greatly adjusted according to the actual situation by pulling the upper anti-disengaging assemblies at the two ends and moving the soft rubber support upwards, and the safety of the pediatric patient is improved. The anti-falling device not only depends on elastic adjustment, so that the practicability of the anti-falling device is improved.

The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.

Examples of the disclosure are directed to adjustable back plates or backboards for a mechanical compression device to accommodate different patient sizes and / or for ease of storage. Examples of the disclosure includes back plates that can be folded, pieced together, or otherwise have a variable distance between connectors that attach to legs of a chest compression device. Examples also include back plates which may have two sides, such as an adult patient side and a pediatric patient side, to accommodate different patient sizes.

Disclosed is a pediatric emergency kit for esophageal tamponade procedures in pediatric patients and methods of use thereof. The pediatric emergency kit includes at least one esophageal balloon catheter for the tamponade of blood flow, and an inflation hand pump equipped with a pressure gauge for inflating a balloon on the balloon catheter. The pediatric emergency kit can be configured to include multiple compartments, optionally, with a first container / compartment containing at least the esophageal balloon catheter and a second container / compartment containing at least the inflation handpump, and optionally a second esophageal balloon catheter. Optionally, both the first and second containers / compartments contain a syringe, a 3-way luer lock stopcock, and / or a guidewire. Also provided are instructions and / or methods of using the kit for correct placement and inflation of the esophageal balloon to effectively manage arterio-esophageal fistulas.

The invention discloses a pediatric surgical operation fixing device which comprises an operating bed and an L-shaped pressing plate located above the operating bed, four supporting legs symmetrically distributed in pairs are fixedly connected to the lower surface of the operating bed, an air bag is installed on the L-shaped pressing plate, a first positioning mechanism used for driving the L-shaped pressing plate to move in the vertical direction is arranged below the operating bed, and a second positioning mechanism used for driving the L-shaped pressing plate to move in the vertical direction is arranged below the operating bed. And the second positioning mechanism is used for driving the L-shaped pressing plate to move in the horizontal direction. According to the device, the first positioning mechanism drives the L-shaped pressing plate to move downwards to the lowest point, so that the L-shaped pressing plate is close to a child patient, then the second positioning mechanism drives the L-shaped pressing plate to move to the preset position in the horizontal direction, so that the L-shaped pressing plate avoids the position where an operation is about to be conducted, and finally the air bag is inflated through an external air pump; according to the device, the air bag is arranged to limit the pediatric patient and prevent the pediatric patient from moving randomly, and vertical movement and horizontal movement of the L-shaped pressing plate can be controlled through the driving shaft, so that the overall convenience of the device is effectively improved.