81 results about "Pediatric patient" patented technology

A system for aiding in a medical clinical trial involving one or more pediatric patients includes a patient passport, individual achievement stickers that are awarded to pediatric patients and that are placed within the patient passport, and an interactive companion toy having distinctive patterns thereon. A camera of a mobile device scans the individual achievement stickers in the patient passport and / or the distinctive patterns on the interactive companion toy, and an interactive incentivization application logic section of the mobile device unlocks and display reward content to the pediatric patient. The interactive companion toy, the mobile application, and the physical passport can be customized to match particular protocols of the clinical trial. The pediatric patient is thus incentivized to participate and continue the clinical trial. Virtual medical play associated with the clinical trial can be practiced on the interactive companion toy in an augmented reality environment. Parents are assisted through automatic text message reminders, and electronic patient-reported outcomes are collected, transmitted, processed, and summarized for visualization and insights via a cloud-based clinical trial portal.

Described herein are pediatric garments for infants and children with medical needs. The pediatric garment is designed to provide quick and easy access to the body, specifically for pediatric patients, and any medical equipment, devices, and / or attachments related to the pediatric care of the patient. The pediatric garment features may include a unique combination of openings with locations that are placed according to the medical needs of a pediatric patient.

The present invention provides methods of treating or preventing atrial fibrillation, atrial flutter, or a combination thereof comprising intravenously administering sotalol hydrochloride to a subject in need thereof. Embodiments of the present invention further provide novel methods of intravenously administering sotalol hydrochloride for example in pediatric patients. The present invention provides a novel intravenous, prophylactic, antiarrhythmic method of sotalol administration.

To provide methods of providing sedation or analgesia to a pediatric patient.SOLUTION: The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More specifically, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during or after surgery.SELECTED DRAWING: Figure 1

The present disclosure is related to a device for gripping catheters that are used in interventional cardiac procedures without causing internal catheter damage. The present disclosure will allow the operator to maintain improved stability and maneuverability compared with current approaches, including, primarily, digital manipulation, which can lead to fatigue, instability and inappropriate catheter movement. Specifically in the pediatric population where small movements can lead to severe and permanent complications, the present disclosure has the potential to increase the safety profile of already high-risk interventional catheterization and electrophysiology procedures.

The invention relates to the technical field of virtual reality, in particular to a traditional Chinese medicine pediatric acupuncture training system combined with virtual reality guidance, which comprises a virtual behavior generation module, a feedback module, an evaluation module and a guidance module. By simulating the physiological behavior of a pediatric child patient, providing sensory feedback, quantitatively evaluating the operation technique in real time and guiding the dialectical diagnosis and treatment process, high-simulation pediatric acupuncture skill training is achieved, and the clinical pertinence of training is effectively improved.

The present invention provides a liquid composition comprising effective amount of Hydroxyurea for oral administration. The invention further discloses liquid formulation in form of ready to use oral suspension which remains stable at room temperature at the time of dispensing, storage and even after reopening of the container comprising the suspension. Also provided is a method of preparing the formulation and treating sickle cell anemia in pediatric patients.

Compositions for intranasal delivery of benzodiazepines, such as diazepam, midazolam, and lorazepam and methods for their use to treat and prevent seizures in pediatric subjects aged 2-5, inclusive. Compositions for rapid therapeutic onset with a decreased incidence and / or severity of adverse effects after administration and methods of improving patient compliance with a prescribed treatment regimen.

A supplement, and a method of treatment utilizing the supplement to elicit positive responses in a patient with neurological conditions is disclosed. The supplement comprises four components: N-acetylcysteine, glycine, choline, and biotin. In the preferred embodiment for treating adult patients, the effective supplement daily dosage comprises at least 1500 mg of glycine, 1500 mg of N-acetylcysteine, 1000 mg of choline, and 1000 μg of biotin. In another embodiment for treating pediatric patients, the supplement may comprise an effective supplement daily dosage of at least 500 mg of glycine, 500 mg of N-acetylcysteine, 250 mg of choline, and 250 μg of biotin. In a method embodiment, regular daily dosages of a supplement comprising over 1 g total of the four components are administered, resulting in improved outcomes among patients with cognitive impediments.

The invention belongs to the technical field of medication safety, and discloses a children medication evaluation method, and the children medication evaluation comprises the following specific operation steps: S1, checking the safety of a medicine: checking the toxicity and adverse events of the medicine according to the medication condition of a child, and particularly paying attention to the special reaction of the child; according to the invention, the body data of the child patient is imported into the evaluation system, so that the body data is compared with the internal information of the data management module, and then similar cases are found and compared with the medication conditions, so that the situation that the cases are far away from the medication conditions is avoided; meanwhile, the medicine use condition of medical staff is checked through the medicine information module and the clinical test management module, the situation that whether medicine conflicts exist or not and potential safety hazards are caused is avoided, the treatment condition is connected through feedback after medicine use of a patient, and data in the data management module are compared; therefore, the medication condition of children can be evaluated conveniently.

This invention discloses an artificial intelligence-assisted method and system for predicting the timing of extubation in pediatric patients, belonging to the field of clinical medical technology. It includes sample information collection: collecting large-sample clinical data of respiratory waveform signals, facial expression video streams, and vital sign data of the child to obtain sample information; and sample information processing: preprocessing the sample information and establishing a repository to store the preprocessed sample information to obtain a database. This invention uses a set state setting method combined with a model generation method, and integrates high-precision ventilator data, child facial expression video data, and vital sign data to predict the timing of extubation, thereby replacing the current subjective judgment method. This provides specific computer-aided decision support for sequential mechanical ventilation treatment during the resuscitation and extubation phase. Simultaneously, different timing prediction models are trained according to different child characteristics to improve the accuracy of computer-aided decision support.

Orodispersible film (ODF) is an innovative drug formulation that allows for adjustable dosing and improved patient compliance. It is administered into the mouth where it dissolves, making it suitable for children. The present invention provides an optimized ODF gel formulation and an optimal ODF containing therapeutic doses of hydrocortisone-type corticosteroids (HTC). This ODF is thin, flexible and transparent, and suitable for production in hospital pharmacy using standard equipment. The ODF of the invention allows accurate hydrocortisone levels to be released systemically in patients in need thereof, and its good physico-chemical stability is herein demonstrated for several months. This opens up new opportunities for use in pediatric patients, notably for children suffering from congenital adrenal hyperplasia.

This invention belongs to the field of medical device technology and discloses an endoscope. The endoscope includes a serpentine joint, an instrument channel, and a camera core wire. A traction wire threading structure is provided on the serpentine joint for the traction wire to pass through. The wall thickness of the traction wire threading structure on the side facing the center of the serpentine joint is less than the wall thickness on the side away from the center of the serpentine joint. The instrument channel is disposed within the serpentine joint, forming a cavity. The axis of the instrument channel is parallel to the axis of the serpentine joint. This embodiment of the endoscope can increase the internal space of the serpentine joint while effectively reducing the outer diameter of the serpentine joint, allowing the endoscope to enter extremely narrow cavities at lesion sites, such as the digestive tract of pediatric patients or severely narrowed lesion areas. This provides opportunities for observation and treatment of these patients, increasing the product's market coverage and application scenarios.

Provided herein are compounds and pharmaceutical compositions comprising a therapeutically effective amount of such compounds, or pharmaceutically acceptable salts, and a pharmaceutically acceptable excipient, and methods of treating neurodevelopmental diseases or disorders (NDD) and developmental and epileptic encephalopathy (DEE), comprising administering such compounds, or pharmaceutically acceptable salts, and pharmaceutical compositions, to pediatric patients.

To provide parenteral nutrition formulations.SOLUTION: The present disclosure relates to multi-chamber containers and to parenteral nutrition formulations, including ready-to-use parenteral nutrition formulations reconstituted from and amino acid formulations. More specifically, the present disclosure relates to formulations comprising butyrate derivatives, specifically arginine butyrate, for use in adult or pediatric patients. The present disclosure further provides methods for reducing or preventing systemic and local inflammation in patients receiving parenteral nutrition, as well as methods for maintaining or improving their systemic and local immunity and intestinal barrier function.SELECTED DRAWING: None

The invention discloses a knee joint moving device for postoperative rehabilitation of children, relates to the technical field of knee joint rehabilitation instruments, and aims to solve the problems of monotonous and repeated training process and insufficient protection design suitability in the prior art. The device comprises a seat and a knee joint moving mechanism, wherein the knee joint moving mechanism comprises a thigh assembly, a shank assembly and a power assembly; the thigh assembly is arranged on the seat; the shank assembly is hinged to the bottom of the front end of the thigh assembly and used for driving shanks of the pediatric patient to move. The power assembly is connected between the thigh assembly and the shank assembly and used for providing power for movement of the shank assembly. Through the arrangement of the guardrail, the inflation piston, the balloon connector and the balloon, after the leg folding action is completed, the rear side of the shank fixing body presses the inflation piston so that gas can be inflated into the balloon through the seat and the guardrail, the process of blowing the balloon can attract the attention of a child, and whether the movement times of the two legs are consistent or not can be judged through the expansion of the balloon.

A pediatric pelvic floor therapy system and method of operating a pelvic floor therapy system. The system may be designed for use by pediatric patients. The system includes non-invasive external electrodes, an electromyography (EMG) device, and a computer or mobile device that integrates gamification to engage users. The electrodes detect muscle activity, and the EMG device processes and transmits the signals wirelessly to the computer or mobile device. The received data is mapped to a gamified user interface that provides interactive game play based on the muscle activity of the user.

This invention relates to the field of cranioplasty materials, and particularly to a pediatric cranioplasty material, its preparation method, and its application. A method for preparing a pediatric cranioplasty material includes: acquiring cranial model data of a pediatric patient; obtaining a dense layer using 3D printing based on the cranial model data; placing a titanium mesh on the dense layer; wherein the titanium mesh comprises multiple titanium strips, each titanium strip having its two ends movably connected to the endpoints of two other titanium strips to form a titanium mesh, and each titanium strip rotating in the same plane about the movably connected point as an axis to extend or contract the titanium mesh; obtaining a porous layer using 3D printing on the dense layer and the titanium mesh based on the cranial model data, the dense layer and the porous layer encapsulating the titanium mesh to obtain the pediatric cranioplasty material. This invention provides a pediatric cranioplasty material, its preparation method, and its application, providing a cranioplasty material with strong mechanical properties and deformation capacity.

1. Name of the product in this design: Pediatric ventilator. 2. Purpose of this design: for use in ventilators specifically for pediatric patients. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The present application belongs to the field of intelligent medical treatment, and particularly relates to a method, device, medium and program product for predicting RMPP based on lung microvessel changes. The method comprises the following steps: S101: acquiring CT images of a pediatric MPP patient; S102: extracting the CT images to obtain quantitative PBV parameters, wherein the quantitative PBV parameters comprise BV10%, wherein BV10% refers to the percentage of blood volume in blood vessels with a cross-sectional area greater than 10 mm2 in total lung blood volume; and S103: if BV10% is higher than a first threshold value, determining that the pediatric MPP patient has a high risk of developing into RMPP, otherwise outputting a prediction result that the pediatric MPP patient has a low risk of developing into RMPP. The present application discovers the prediction effect of microvessel changes in CT on the occurrence and development of RMPP by quantitatively measuring the microvessel changes, realizes the clinical value of early diagnosis of RMPP, and thus drives early treatment in the clinic.

Apparatus and methods for utilizing a soft robot to facilitate standing and / or walking of pediatric patients, particularly patients suffering from dyskinesia, such as cerebral palsy. Such a soft robotic device may include a fabric pneumatic actuator that, upon inflation, generates the necessary torque along upper and lower contacts of the device to assist in movement of the patient, particularly in joint extension walking, standing, or sitting-to-standing movement. Compared with a fabric pneumatic actuator with an upright or isotropic structure, the concave structure can provide a larger torque angle and can also avoid friction and extrusion generated at the glenoid fossa. The actuator is soft, light in mass, good in compliance, and capable of providing comfortable joint extension in a multi-center trajectory. The actuator can be incorporated into a joint protector or an exoskeleton, and is very suitable for sensitive, soft and weak pediatric patients with dyskinesia, especially infants with cerebral palsy.

The invention discloses a pediatric patient anesthesia recovery state evaluation device and an evaluation method thereof, and relates to the field of intelligent medical treatment, the device comprises a double-gas-path module, the double-gas-path module comprises a main channel and an auxiliary channel, the main channel is used for collecting exhaled gas, and the auxiliary channel is used for providing low-flow oxygen to assist ventilation; the adjustable nose wing fixing clamp is connected with the double-gas-path module, the adjustable nose wing fixing clamp is used for being attached to the nasal septum of a monitored person, the miniature nasal cavity adaptive sensor module comprises a flexible silica gel substrate, a miniature infrared light source and a light-sensitive detector are integrated on the flexible silica gel substrate, and the miniature infrared light source and the light-sensitive detector are connected with the adjustable nose wing fixing clamp. The micro nasal cavity adaptive sensor module is arranged on the inner wall of the main channel; the airflow sampling module is arranged on the inner wall of the main channel. The invention provides a non-invasive, real-time, intelligent and high-precision solution for a high-risk and low-tolerance scene of postoperative anesthesia recovery of a pediatric patient.

The present invention is directed to the use of cangrelor for the treatment and / or prevention of shunt thrombosis in patients suffering congenital heart diseases undergoing shunt surgery. The invention is also directed to the use of cangrelor for the treatment and / or prevention of stent thrombosis in pediatric patients undergoing stent implantation.

The present invention relates to a method for treating an influenza virus infection, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection, wherein the compound has one of the formulae (I) and (II), as set forth herein, or is a pharmaceutically acceptable salt thereof, and wherein dosages set forth herein are used.

The utility model relates to the field of medical care, in particular to a safety bed guardrail for an ophthalmic ward and a bed. A sensing device is arranged on the upper surface of a transverse rod of the bed guardrail, the sensing device generates a first signal when responding to an object approaching the upper surface of the transverse rod, a pressure sensing device is arranged between the transverse rod and a telescopic vertical rod, and the pressure sensing device generates a second signal when responding to pressure applied to the telescopic vertical rod by the transverse rod; the lifting mechanism is electrically connected with the induction device and the pressure sensing device through a controller, and the controller responds to the first signal and the second signal to control the lifting mechanism to do stretching movement so as to increase the height of the cross rod. When most of the body of the patient is close to the upper portion of the cross rod and certain pressure is exerted on the cross rod, the lifting mechanism is controlled to stretch out, the height of the bedrail is increased, the patient is prevented from turning over the bedrail, the patient is effectively prevented from falling off the bed, the bed is particularly suitable for special scenes such as ophthalmology wards, and the diversified requirements of old people and child patients are met; and the safety and nursing efficiency of a ward are improved.

The invention belongs to the technical field of microbial infection treatment and medicine preparation, and discloses various applications of trans-cinnamyl aldehyde in resistance to enterococcus faecalis infection, a related pharmaceutical composition and a treatment method. It is found for the first time that trans-cinnamyl aldehyde has a remarkable inhibition effect on enterococcus faecalis, can destroy a biological membrane of the enterococcus faecalis and promote intestinal mucosa repair after enterococcus faecalis infection, and can selectively inhibit enterococcus faecalis without destroying intestinal probiotics such as lactobacillus and bifidobacterium. The invention also provides a pharmaceutical composition containing trans-cinnamyl aldehyde, and the composition is suitable for pediatric patients to treat intestinal enterococcus faecalis infection for a long time and can reverse the drug resistance of enterococcus faecalis to vancomycin. In addition, the problems that in existing enterococcus faecalis infection treatment, vancomycin is resistant to drugs, a biological membrane is difficult to remove, and probiotic balance and pediatric medication safety are affected are solved, and important clinical application value is achieved.

The invention relates to the technical field of intelligent pre-examination, and discloses a pain pre-examination grading system and method based on progressive intelligent interaction, and the system comprises an information collection device which is used for obtaining a subjective description text and a touch screen labeling operation, and generating pain position information; the collaborative decision engine takes the pain position information as an initial anchor point and executes a progressive verification process guided by diagnosis hypothesis credibility evolution; sequentially completing generation and maintenance of a diagnosis hypothesis set, screening a to-be-verified target diagnosis group based on credibility distribution, generating a targeted inquiry instruction, and updating the credibility according to user reply until a convergence condition is met; and the grading output device is used for generating a pre-examination grading result based on the converged diagnosis hypothesis set and the pain position information. The method corresponds to the system. According to the method, the problem of pre-examination triage caused by unclear child patient pain description and possible distortion of family member description is solved, and the accuracy and efficiency of triage are improved.

Subphenotypes of MODS associated with poor prognosis have been identified using multiomics analysis of pediatric patients with and without sepsis. Compositions and methods for the diagnosis and management of severe MODS are disclosed.

Compositions and methods for treating hair loss and / or nail brittleness, fragility, and pitting, particularly in pediatric patients, using topically administered JAK / STAT inhibitors and one or more penetration enhancer are described herein.