The invention provides a preparation method of a herba siegesbeckiae luoda
capsule. The preparation method comprises the following steps: step 1, weighing raw traditional Chinese medicinal materials according to a prescription amount; step 2, crushing
gastrodia elata into
fine powder, then mixing with
borneol and
calculus bovis factitius,
grinding into
fine powder, sieving, and uniformly mixing for later use; step 3, carrying out
reflux extraction on
ligusticum wallichii for 2-3 times by using
ethanol, filtering, combining filtrates, and recovering
ethanol to obtain a
ligusticum wallichii extracting solution; step 4, mixing herba siegesbeckiae, leech, ginger processed
pinellia,
gentiana macrophylla, pseudo-
ginseng, safflower, peach kernel,
salvia miltiorrhiza and
arisaema cum bile, adding water for decoction, filtering after decoction, and combining filtrate; step five, soaking musk and ground beetles in water for 1-2 hours, then performing
microwave radiation treatment, separating filter residues and filtrate after
microwave radiation,
drying the filter residues, and crushing the dried filter residues into
fine powder; and step 6, combining the
ligusticum wallichii extracting solution in the step 3, the filtrate in the step 4 and the filtrate in the step 5, performing vacuum concentration to obtain thick paste with the
relative density of 1.30-1.40, performing
vacuum drying, crushing the obtained dried substance into fine
powder, uniformly mixing the fine
powder with the fine
powder in the step 2 and the fine powder in the step 5, and preparing the
capsule with a pharmaceutically acceptable carrier or
excipient. The musk and the ground beetles are treated together, the special fragrance of the musk is used for covering the bad smell of the ground beetles, the fishy smell of the ground beetles is effectively weakened, and the
medicine taking compliance of a user is improved.