435 results about "Secondary infection" patented technology

The invention discloses a skin burn repair material and a preparing method thereof, and belongs to the field of biomedicine. A functional loading substance is added into a polymer to prepare the repair material through the coaxial electrostatic spinning process, and the upper surface layer micro-nano structure is adjusted so that the repair material can resist adhesion of outside microorganisms and bacteria. The prepared repair material containing the functional loading substance with antibacterial, antiphlogistic and repair promoting functions repairs the skin burn area in a targeted mode based on the characteristics of different stages of the burnt skin repair process. The adopted base material has high biocompatibility, secondary damage to the wound region of traditional medical gauze when fresh dressing is changed for a wound is avoided, and secondary infection caused by external factors can be effectively resisted. The skin burn repair material and the preparing method thereof can be effectively applied to biomedicine related fields and have the possibility of extensive clinic application.

This invention relates to a synthetic nutritional composition suitable for use in the prevention of secondary infections following a viral infection characterised by neuraminidase activity comprising a sialylated oligosaccharide and N-acetyl-lactosamine and / or an oligosaccharide containing N-acetyl-lactosamine The invention further extends to the use of such a composition in the prevention of secondary infections such as otitis media.

An intra-tracheal sputum aspiration apparatus arranged so that air feeding to and air evacuation from trachea (13) by means of artificial respirator (12) are carried out through tracheal cannula (14) and so that in the event of sputum clogging, tube pump (16A) is operated to thereby attain discharge of sputum through suction tube (15) to the outside of the body by means of a negative pressure produced thereby. By virtue of the employment of the tube pump (16A) as a sputum aspirator (16), the intra-airway pressure by the artificial respirator (12) would have substantially no fluction even when a positive pressure is applied to the lungs. Consequently, sputum disposal can be accomplished while maintaining artificial artificial respiration, so that there can be prevented any secondary infection by infectious agents discharged from sputum collection bottle (17) into the air.

An intra-tracheal sputum aspirating apparatus arranged so that air feeding to and air evacuation from trachea (13) by means of artificial respirator (21) are carried out through tracheal cannula (14) and so that in the event of sputum clogging, tube pump (16A) is operated to thereby attain discharge of sputum through suction tube (15) to the outside of the body by means of a negative pressure produced thereby. By virtue of the employment of the tube pump (16A) as sputum aspirator (16), the intra-airway pressure by the artificial respirator (12) would have substantially no fluctuation even when a positive pressure is applied to the lungs. Consequently, sputum disposal can be accomplished while maintaining artificial respiration, so that there can be prevented any secondary infection by infectious agents discharged from sputum collection bottle (17) into the air.

The invention discloses Metarhizium anisopliae and application of Metarhizium anisopliae. The Metarhizium anisopliae provided by the invention is Metarhizium anisopliae JF-6213 with CGMCC No. 5952 registered in China General Microbiological Culture Collection Center. The strain (Metarhizium anisopliae) has good production traits and strong spore production capacity, strong insecticidal activity to sugarcane moth borer, good secondary infection to sugarcane moth borer, has 7.44 days LT50 (lethal time of 50%) to 3-4 years sugarcane moth borer; the strain is used for preparing insect killing fungus preparation which can effectively control population quantity of sugarcane moth borer; moreover, Metarhizium anisopliae JF-6213 has strong pathogenicity to brontispa longissima, asiatic migratory locust, leechee stinkbug and Dysmicoccus neobrevipes Beardsley, strong secondary infection capability and high stability and is quite applicable to tropical and subtropical areas.

The invention describes a method of producing extracts from the seeds of meadowfoam, brassicas and crambe plants. A number of subsidiary processes and steps are shown in order to extract differing fractions of oil. Products produced from the above method are also described including uses and methods of these products which include a variety of skin conditions including eczema, facial eczema, dermatitis, external ulcers, welts, rashes, insect bites, allergic reactions and other irritations, burns, wounds, psoriasis, acneiform eruptions, dryness, dry skin, irritation, skin atrophy, secondary infections and the like. The extracts are also described as being a useful compound for treatment of the symptoms of such skin conditions as described above. In particular the use and extraction of glucosinolate (GSL), thiocyanates (TCL) and isothiocyanates (ITCL) is described.

The invention relates to a metal base polyquaternary ammonium salt silica gel coating antibacterial finishing technology. The technology comprises the following steps: high-efficiently shearing and mixing double terminated vinyl silicone oil, dimethyl silicone oil, silicone oil containing hydrogen, EP-DC5700, PETA, and nano silver at room temperature so as to obtain an antibacterial coating silica gel; painting the prepared antibacterial coating silica gel on a basic material by using a painting knife, wherein the coating amount of the coating layer gel is 10 to 50 g / cm<2>; fixing the basic material coated by the antibacterial coating silica gel on transmission rollers arranged on the front side and rear side of a coating machine, and then placing the basic material in a conveying belt frame of a 200 KeV low-energy electronic accelerator to carry out a radiation curing treatment. An electronic beam radiation curing technology is adopted, and the technology has the advantages of high efficiency, short technological process, and long-lasting effect; the polyquaternary ammonium salt silica gel is well combined with fiber molecules under the radiation; the modified fiber has a long-lasting bacterium killing effect, will not penetrate into the skin and cause adverse effects such as secondary infection, has a good safety property, can effectively inhibits the growth of bacteria, and has good properties of thermal stability, weatherability, ultraviolet resistance, hygroscopicity and softness. The coating material can also be applied to various textures, can be used as a surface coating, and has the advantages of long lasting effect, no toxicity, and no pollution.

The invention relates to a wound coating agent which comprises the following components based on the ratio in parts by weight: 6-benzyl purine: natural brassin: plant vitamin C: zinc pyrithione: super-absorbent resin: water is equal to (0.5-8):(0.4-5):(6-10):(3-15):(30-40):(10-25). The wound coating agent can be used for improving the meristematic capability of callus tissues, promoting the healing of a wound and reducing scars of the wound. The wound coating agent can effectively kill a variety of harmful pathogens, and rapidly form a protective film on the wound of a plant, thus avoiding secondary infection during the transplantation and transportation processes of the plant. The wound coating agent can further supplement a variety of nutritional ingredients for keeping vitality, prevent the loss of water and nutrient, contain a large number of plant high-level nutritional elements, effectively prevent the loss of the water and nutrient of the wound of the plant and increase nutrition. The wound coating agent can be used for improving the capabilities of disinfection, disease resistance and corrosion resistance and has no toxicity or side effects. The wound coating agent can rapidly condition and heal the wound and an incision, prevent the wound from rotting, prevent the evaporation and loss of the nutrient and the water and promote the robust growth of the plant.

The invention relates to a method for preparing a veterinary oxytetracycline-artemisinin injection and clinical application of the veterinary oxytetracycline-artemisinin injection. Raw materials of the injection mainly comprise oxytetracycline, artemisinin, trimethoprim, flunixin meglumine, magnesium oxide or magnesium chloride, an antioxidant, a pH regulator, a compound organic solvent and water. As a veterinary compound preparation, the veterinary oxytetracycline-artemisinin injection is mainly used for treating infectious diseases and secondary infection which are caused by sensitive gram positive bacteria and negative bacteria, eperythrozoon, rickettsia and mycoplasma. The method for preparing the veterinary compound oxytetracycline-artemisinin injection is simple, the production process is mild, the chelating temperature is low, the stability is high, and the injection is convenient to use and is suitable for industrialized production.

The invention provides methods for inducing an immune response in a vertebrate host against a protozoan parasite, comprising administering to the host a live protozoan parasite that is genetically engineered to disrupt a stage-specific gene function that is required by the protozoan parasite to establish a secondary infection in the vertebrate host. Representative protozoan parasites belong to the phyla Apicomplexa and Kinetoplastida. The vertebrate host may be a mammal or a bird.

The invention discloses a traditional Chinese medicine preparation for wound hemostasis, anti-inflammatory and tissue regeneration. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicines in parts by weight: 1-5 parts of salvia miltiorrhiza, 1-5 parts of drynaria rhizome, 1-4 parts of bletilla, 1-4 parts of radix angelicae, 1-5 parts of crude rhubarb, 1-4 parts of rhizoma coptidis, 1-4 parts of scutellaria, 1-5 parts of dandelion, 1-5 parts of japanesehoneysuckle, 0.5-1.2 parts of dragon's blood, 1-5 parts of crude gardenia, 1-3 parts of monkshood, 1-3 parts of polygonum cuspidatum, 0.5-1.2 parts of moxibustion myrrh, 1-2 parts of rhizoma corydalis, 1-3 parts of Chinese gall and 1-3 parts of borneol. The traditional Chinese medicine preparation is used for wound hemostasis and anti-inflammatory, and has the advantages of remarkable curative effect, fast hemostasis and no secondary infection of a wound.

Pharmaceutical compositions are provided which comprise effective amounts of antimicrobials, anti-inflammatories, and antihistamines, to provide an ulcer medication which prevents secondary infections and promotes healing while providing immediate relief from pain. The composition may be used to treat a variety of ulcers including but not limited to intraoral aphthous ulcers and non-oral lesions.

The invention discloses a new traditional Chinese medicine compound for treating intestinal obstruction and a preparation method thereof, wherein the traditional Chinese medicine compound of the invention mainly comprises the following raw material medicines: rhizoma cyperi, storax, dalbergia wood, rhubarb, dried orange peel, fruit of immature citron, pangolin, grass-leaved sweetflag, angelica, brush-cherry seed, maticated leaven, malt, radish seed, rhizoma sparganii, rhizoma zedoariae, tambac, fumitory, radix curcumae, rhizoma ligustici wallichii, salvia miltiorrhiza, peach kernel, safflower, magnolia officinalis, amomum villosum and the like. The traditional Chinese medicine compound of the invention can be prepared into any common oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can markedly improve the symptoms of abdominal distension as a drum, abdominal pain, vomit, constipation, absent bowel sounds, flatus and aroused body fluid and electrolyte loss, intestinal wall circulatory disturbance putrescence and secondary infection and the like, and has exact clinical curative effect, remarkable curative effect and rapid effect taking. Because the traditional Chinese medicine compound of the invention is combined by basically adopting medicine-food homologous medicaments specified in National Formulary, the traditional Chinese medicine compound has the advantages of low cost, basically no toxic or side effect and the like.

The invention relates to a multifunctional enzyme that can be derived from crustaceans or fish. The enzyme has at least one of a chymotrypsin, trypsin, elastase, collagenase and exo peptidase activity, and a molecular weight between about 20 kd and about 40 kd as determined by SDS PAGE. Preferably, the multifunctional enzyme has substantial anti cell-cell adhesion activity. Preferably, the multifunctional enzyme has substantial homology with the krill multifunctional enzyme. These enzymes are useful for treating viral infections such as herpes outbreaks, fungal, bacterial or parasitic infections, including the primary and secondary infections of leprosy, colitis, ulcers, hemorrhoids, corneal scarring, dental plaque, acne, cystic fibrosis, blood clots, wounds, immune disorders including autoimmune disease and cancer. Additionally, the invention relates to a method of purifying the multifunctional enzyme, and to a preparation of essentially purified multifunctional enzyme.

The present invention relates to preparation of a new medicine Nifuratel nysfungin vagina tablet for gynecologic antisepsis and anti-inflammation. Nifuratel nysfungin can play a more complete role in curing mixed vagina infection (candida, trichomonas and bacteria) and pathogen which can not be or can not be timely and clearly diagnosed and preventing mildew secondary infection and recurrence after the treatment of other medicines. The present invention can be used for curing bacterial vaginopathy, trichomonas vaginitis, monilial vulvovaginitis, and vagina mixed infection. The advantage of the present invention lies in that the added pH buffer system ensures pH of the medicine is within 3.5 to 4.0 close to the physiological pH of vagina, thus effectively protecting the physiological environment of vagina, providing the appropriate living conditions beneficial to flora in vagina and promoting the recovery of diseases.

The invention relates to a plague-removing and cystoma-treating extracted traditional veterinary medicament used for treating damage by bursa of fabricus in chicken and secondary infection caused by the damage. According to monarch, minister, assistant and guide, the formula of the medicament comprises seventeen traditional Chinese medicines such as honeysuckle, fructus forsythiae, scutellaria baicalensis, cape jasmine, isatis indigotica fort, rhizoma anemarrhenae, the root of red-rooted salvia, cyrtomium fortunei and the like. The seventeen traditional Chinese medicines are smashed, decocted, extracted and concentrated, gypsum powder is added, and mixing is carried out, thus pure traditional Chinese powder and tablet are prepared, no toxic or side effect is produced; and the medicament is safe to use, and has small possibility of recrudesce, bacteria have small possibility of producing medicament resistance, and veterinary medicament residue and social public nuisance can be avoided.

The invention discloses a fermented traditional Chinese medicine for treating the reduction of the egg production of laying hens. The fermented traditional Chinese medicine is prepared from the following traditional Chinese medicine raw materials in parts by weight by fermentation by virtue of zymophyte: 1-15 parts of acanthopanax, 1-15 parts of common curculigo rhizome, 1-15 parts of polygonum multiflorum, 1-15 parts of Chinese angelica, 1-15 of folium artemisiae argyi, 5-20 parts of dangshen, 5-20 parts of bighead atractylodes rhizome, 1-10 parts of hawthorn, 1-10 parts of medicated leaven, 1-10 parts of malt and 1-10 parts of pine needles. Meanwhile, the invention discloses a preparation method of the fermented traditional Chinese medicine. The preparation method comprises the following steps: mixing and crushing the traditional Chinese medicine raw materials, screening with a 50-80 mesh sieve, carrying out high-temperature sterilization, adding water and zymophyte, and then putting in a fermentation tank for fermentation so as to obtain the product; and drying, sieving and subpackaging the product. The fermented traditional Chinese medicine prepared by the method has the advantages that the content of effective components and active materials is high so that the fermented traditional Chinese medicine can be efficiently absorbed by animals; and the zymophyte for fermentation is beneficial to the maintenance of intestinal tract environments of livestock and poultry and the prevention and treatment of secondary infection and other intestinal diseases.

The invention discloses a compound sulfamonomethoxine / compound sulfamonomethoxine sodium injection which is prepared from main components and auxilary components, wherein the main components comprise 5-20 parts by weight of sulfamonomethoxine / sulfamonomethoxine sodium, 1-4 parts by weight of diclofenac sodium and 1-4 parts by weight of trimethoprim and the auxilary components comprise 0.2-0.4 part by weight of antioxidant, 40-70 parts by weight of organic solvent, 0.2-1 part by weight of regulating reagent and 10-20 parts by weight of water for injection. The injection prepared by the invention can provide effective treatment on secondary infection and mixed infection of streptococcicosis, toxoplasmosis, eperythrozoonosis, colibacillosis, asthma and other diseases, has obvious effect if applied for a long term, strong effect enhanced by several times or dozens of times, hardly generates drug resistance and has the advantages of less consumption, less application times, little irritation and quick treatment effect, can treat both symptoms and root causes, save production cost, improve product additional value and reduce toxic or side effects caused by mismatching of medicaments during treatment.

The invention discloses a method for utilizing test tube potatoes for efficiently producing detoxication breeder's seeds.The method comprises the following steps of green net house preparation, test tube potato germination acceleration, matrix preparation, cultivation frame preparation, environmental disinfection, sowing, management after planting and breeder's seed harvesting and storing, wherein the test tube potatoes whose dormancy is not broken are soaked with a gibberellin solution for germination acceleration; a matrix is formed by mixing vermiculite and mushroom dreg, and potassium sulfate compound fertilizer is applied to the matrix; sowing is carried out according to the amount of 250 particles / m<2>, the planting distance is 5 cm, and the line distance is 8 cm; management after planting comprises temperature management, water management, matrix cultivation, fertilization management and disease and pest preventing management; after being harvested, the breeder's seeds are sorted and packaged into detoxification seed potato net bags and stored at the temperature ranging from 2 DEG C to 4 DEG C.The method has the advantages of being high in yield, high in economic benefit, storable and convenient to transport, secondary infection of pathogenic bacteria is eradicated, the potatoes can be planted mechanically, convenience is brought to cultivation and management, the survival rate is high, and the method has great significance in demonstration and popularization of production scales of detoxication breeder's seeds.

The invention relates to an expansion suppository of clotrimazole or a salt thereof. The expansion suppository consists of the clotrimazole or the salt thereof, a fat-soluble matrix and an expandable expansion carrier. The invention also relates to a preparation method and a detection method for the expansion suppository. The expansion suppository of the clotrimazole or the salt thereof provided by the invention adopts seven original leading technologies, wherein the addition of the expansion carrier applies six technologies including a suppository disposable filling integration technology, an inner core expansion coefficient control technology, an ergonomic suppository type technology, a treating and cleaning integrated preparation formulation, a vagina-attached administration technology and a side leakage prevention suppository body design; and poloxamer and a sustained-release material in the expansion suppository apply a medicament long-acting layered release technology. The expansion suppository of the clotrimazole or the salt thereof disclosed by the invention has the beneficial effects of having high efficiency, long acting, safety and few side effects, preventing the overflow of medicament liquid, cleaning the vagina, preventing secondary infection and the like.

The invention relates to a compound composition resisting plant viruses which comprises the effective ingredients of biological-derived plant-virus-resisting preparation and Tolfenpyrad at a weight ratio of 90:1-1:180. According to the invention, the biological-derived plant-virus-resisting preparation and Tolfenpyrad are not simply supposed, but supplemented to each other; and the compound composition can kill insects spreading viruses while inhibiting plant virus, cut off the virus infection route and avoid secondary infection of the viruses, thereby greatly improving the control effect on black-streaked dwarf disease of south rice and corn dwarf disease.

The invention discloses a compound sodium sulfadimidine injection liquid for a pig and a preparation method thereof, aiming at providing a compound kanamycin sulfate injection liquid which has fast effect for treating toxoplasmosis of the pig, addresses both the symptoms and root causes, reduces the time and dosage of used drug and has convenient drug usage, and a preparation method with simple technique and easy implementation. Each 100L injection liquid comprises: 5 to 20 sodium sulfadimidine, 1 to 10kg of lincomycin hydrochloride, 5 to 20kg of doxofylline, 1 to 4kg of trimethoprim, 0.2kg of sodium bisulfite, 0.01kg of EDTA-2Na, 40kg of propylene glycol, 10kg of 95% alcohol and the balance of water for injection. The injection liquid has fast effect for toxoplasmosis of the pig, addresses both the symptoms and root causes, can effectively treat and prevent secondary infection of bacterium, reduces drug resistance of pathogenic microorganism and leads the pig to accelerate restoring. Simultaneously, the compound sodium sulfadimidine injection liquid is an injection liquid and has convenient use.

The invention discloses a human body temperature detection method, system and device and a thermal infrared image processor. The method comprises the following steps of: acquiring a first image acquired by thermal infrared image acquisition equipment; determining a first image area containing a specified human body part of a target object in the first image; and determining the temperature of thespecified human body part according to the image information of the first image area. Temperature detection can be carried out on designated human body parts of multiple target objects at the same time, temperature detection is carried out on the designated human body parts of the target objects, the temperature detection precision is high, high-temperature individuals can be rapidly removed in time at the same time, and centralized infection or secondary infection is avoided. Meanwhile, non-inductive detection is carried out by acquiring the first image acquired by thermal infrared image acquisition equipment, and people flow can be rapidly evacuated without staying. Moreover, temperature detection is carried out on designated human body parts of the target objects, interference of an environment high-temperature object is avoided, false alarm of high temperature of hair exposed to the sun is avoided, and wrong detection and false detection are eliminated.

The invention relates to the technical field of NK cell in-vitro amplification, in particular to a NK cell transfection efficiency improving method. In lentivirus infection of NK cells, an auxiliary infection agent 1 is added while a CAR-containing lentivirus carrier is added in primary infection; an auxiliary infection agent 2, an auxiliary infection agent 3 and an auxiliary infection agent 4 areadded while a CAR-containing lentivirus carrier is added in secondary infection; the auxiliary infection agent 1 refers to polybrene solution, the auxiliary infection agent 2 refers to IL2 solution,the auxiliary infection agent 3 refers to IL12 solution, and the auxiliary infection agent 4 refers to PHA solution. According to a Car-NK transfection method, different auxiliary infection agents areadded in a transfection process, NK cell transfection efficiency is imiproved, and NK cell lentivirus transfection efficiency can be improved from less than 10% to 50%-60%.

The invention relates to a medicinal composition and injecta for curing avian toxoplasmosis, and a preparation method thereof. The medicinal composition comprises the following components in percentage by weight: 18 to 36 percent of sulfamonomethoxine, 16 to 65 percent of sulfamethoxazole, 7 to 18 percent of trimethoprim, 4 to 14 percent of pyrimethamine and 6 to 16 percent of nonsteroidal anti-inflammatory medicament. The injecta comprises the following components in percentage by weight: 5 to 10 percent of sulfamonomethoxine, 4 to 20 percent of sulfamethoxazole, 2 to 5 percent of trimethoprim, 1 to 3 percent of pyrimethamine, 1.5 to 4 percent of nonsteroidal anti-inflammatory medicament, 5 to 10 percent of polyethyleneglycol-400, 10 to 30 percent of propylene glycol, 30 to 60 percent of alpha-pyrrolidone, 0.1 to 0.2 percent of antioxidant, 0.01 to 0.02 percent of metal complexing agent and the balance of water for injection. Sulfamonomethoxine, sulfamethoxazole, trimethoprim and pyrimethamine are jointly applied and a long-acting preparation is prepared by adopting composite solvent, so that the medicinal composition and the injecta can prevent the secondary infection of other pathogen at the same time of destroying and expelling toxoplasma so as to relieve different symptoms and complicating diseases caused by the toxoplasma.

The invention relates to full-automatic throat swab collecting equipment. The collecting equipment comprises a supporting platform and a lifting chair arranged in a matched manner, wherein a fixing frame is arranged on the supporting platform, a fixing support is arranged on one side of the fixing frame, a three-degree-of-freedom parallel movement apparatus is arranged on the fixing frame, a collecting assembly is arranged on one side of the three-degree-of-freedom parallel movement apparatus and is used for collecting throat swabs, an information collection assembly is arranged on the collecting assembly in a matched manner, and a sensor assembly is arranged on the three-degree-of-freedom parallel movement apparatus in a matched manner. The high-precision movement and the real-time detection of a human body interaction force are realized through the information collection assembly and the sensor assembly, and the safety of people and equipment is guaranteed while the movement precision is improved. The full-automatic equipment can realize that a patient autonomously carries out the throat swab collection work, the secondary infection phenomenon of doctor operations is avoided, andtherefore the efficiency and safety of the collection work can be improved.

The invention relates to a recombinant human interferon alpha2b vagina expansive suppository, and a preparation method and a detection method thereof. The recombinant human interferon alpha2b vagina expansive suppository comprises a medicine-containing matrix mainly composed of recombinant human interferon alpha2b and a matrix, and an expansive carrier; herba corydalis bungeanae extract is added into the medicine-containing matrix, excellent synergistic effect with recombinant human interferon alpha2b is achieved, and after adding of the herba corydalis bungeanae extract, disease-resistant effect of one hundred thousand units of recombinant human interferon alpha2b is equal to that of three hundred thousand units of recombinant human interferon alpha2b; the medicine-containing matrix also comprises a mixture of kaempferol-3-O-beta-D sophoroside and lauryl sodium sulfate, and magnetic microspheres prepared from a crosslinked substance composed of magnetic iron crosslinked esterfied cassava modified starch and chitin-methyl cellulose; and curative effect of the recombinant human interferon alpha2b vagina expansive suppository is increased. According to the recombinant human interferon alpha2b vagina expansive suppository, six advanced original technologies are adopted, medicine liquid leakage is prevented, stability is high, curative effect lasts long, and secondary infection is prevented.