10results about How to "Guaranteed effective concentration" patented technology

The invention provides mupirocin ointment as well as a preparation method and an application method thereof. The weight of mupirocin accounts for 0.1-0.5% of the total weight of the ointment. The water-soluble matrix is selected from polyethylene glycol, glycerol, propylene glycol or a mixture thereof. The stability and the curative effect of the medicine can be improved, and meanwhile, the safety and the use convenience of the ointment are ensured.

The invention discloses recombinant bacillus subtilis with the surface displaying Edwardsiella tarda outer membrane protein OmpA and vibrio cholerae enterotoxin CTB fusion protein, a construction method and application, spore capsid protein CotY serves as an anchor point, coding genes of OmpA and CTB are recombined into a genome of bacillus subtilis 168 in a homologous double cross mode, and the recombinant bacillus subtilis is obtained. The recombinant bacillus subtilis can be stably inherited in the bacillus subtilis and displays edwardsiella tarda outer membrane protein OmpA and vibrio cholerae enterotoxin CTB on the spore surface; after fishes and mammals orally immunize the Edwardsiella tarda, the survival time and the survival rate of bodies infected with the Edwardsiella tarda are remarkably improved; the recombinant bacillus subtilis is used as an oral vaccine type micro-ecological immune preparation for preventing and treating Edwardsiella tarda infection of fishes and mammals, the immune procedure is remarkably simplified, the immune stress is reduced, the labor cost is saved, the effective action concentration in the intestinal tract is ensured, and the organism is induced to generate specific immune response.

This invention discloses a compound traditional Chinese medicine powder inhaler for respiratory tract infections and its preparation method, relating to the field of pharmaceutical formulation technology. The compound traditional Chinese medicine powder inhaler for respiratory tract infections is composed of polysaccharide composite gel microspheres, forsythia, scutellaria, honeysuckle, and isatis root. The polysaccharide composite gel microspheres are composed of seaweed sulfated polysaccharide, lentinan, calcium chloride, and curcumin. Seaweed sulfated polysaccharide, lentinan, curcumin, and calcium chloride cross-link to form a three-dimensional network spherical structure, improving the particle morphology and flowability of the micropowder. Furthermore, due to its good hygroscopic and moisturizing properties, it competitively reduces the moisture absorption of the micropowder, preventing aggregation and further improving flowability. In addition, the gel microspheres have excellent adhesion, adhering to the infection site after entering the respiratory tract, reducing expulsion losses due to respiration, maintaining an effective drug concentration at the infection site, and improving therapeutic efficacy.

The utility model relates to a kind of descaling devices, including mainframe box, processing pipeline is located in mainframe box and multiple groups are arranged in parallel, first closed chamber and second closed chamber are arranged at the both ends of mainframe box, the both ends of processing pipeline are communicated with first closed chamber and second closed chamber respectively, first closed chamber and second closed chamber are communicated with one end of descaling pipeline, the other end of descaling pipeline is communicated with medicament storage tank, medicament storage tank imports descaling reagent by pump, pump circulates reagent along first closed chamber, second closed chamber and processing pipeline, by high efficiency, the scale layer of these parts is removed, avoid the case that water passage flow is small, ensure the entire water system's unobstructed, maintain the purification efficiency of purification mainframe to cooling circulating water, ensure that equipment can be stably and efficiently operated, reduce the risk that equipment efficiency is reduced due to scale layer accumulation, reduce the maintenance cost and energy consumption cost of enterprise.

The present application relates to sewage treatment technical field, disclose a kind of membrane aeration biological membrane reactor's operating method and operating device, sewage treatment system.The operating method has at least one control cycle during the continuous operation of reactor, the cycle includes: pre-control step, provide negative pressure pulse to membrane assembly inside, the normal compressive stress directed to membrane silk inside is applied to the biological membrane attached to the outer surface of membrane, so that the microstrain of outer layer structure is generated;Fluidized cutting step, add and fluidize circulating cutting microparticles to reactor, and microparticles are rolled cutting to the surface of biological membrane under the driving of fluid.By the cutting action of cutting microparticle and negative pressure pulse, the outer layer of biological membrane is selectively stripped from invalid biomass.The present application realizes the fine control from inside to outside to biological membrane under the condition of not interrupting sewage treatment process, can long-term maintain biological membrane in thin, high-activity ideal mass transfer state, effectively solve the problem that mass transfer efficiency attenuates with operating time.

The invention relates to a detection material for detecting a GABABR antibody and a preparation method of the detection material. The detection material for detecting the GABABR antibody comprises the following components: an antibody detection plate, a working solution, PBS (Phosphate Buffer Solution), a fluorescent secondary antibody and a mounting medium, by introducing the composite material of the modified trehalose, the chitosan and the polyvinyl alcohol to the surface of the glass slide, the adhesive force of the antigen protein is remarkably improved by adopting the technical scheme. The modified trehalose not only provides higher surface activity, but also forms a stable binding layer by optimizing the interface action of the antigen and the carrier, thereby remarkably reducing the loss of the antigen protein caused by washing and operation steps in the detection process. According to the design, the problem of insufficient antigen fixing force in the prior art is solved, the effective concentration of antigen protein is ensured, and the detection sensitivity and the result reliability are improved.

The invention discloses an aggressive agent for observing chromium carbides in stainless steel as well as a preparation method and application of the aggressive agent. The aggressive agent comprises the following components in parts by weight: 15-20 parts of water, 5.9-11.8 parts of hydrochloric acid, 3.9-7.9 parts of ethanol and 3-5 parts of ferric trichloride. The erosion agent special for observing the chromium carbide is prepared by optimizing the ratio of hydrochloric acid to water and adding a proper amount of ethyl alcohol, and the eroded chromium carbide is in a bright white ball shape, a water drop shape or a granular shape with a clear boundary and is embedded at a crystal boundary or in a crystal grain; the form of the precipitated chromium carbide in the stainless steel can be clearly observed, and the component content of the stainless steel can be analyzed.

The invention discloses a preparation method of pH gradient active drug loading type maqui berry anthocyanin-curcumin compound lipidosome, belongs to the fields of biological medicines, food science and nutritional health-care products, and particularly relates to a nano drug delivery system and preparation of functional foods and dietary supplements. According to the method, the water-soluble maqui berry anthocyanin and the fat-soluble curcumin are efficiently entrapped at the same time by utilizing a unique double-layer structure of the lipidosome and through a film dispersion-hydration technology. Soybean lecithin and cholesterol are used as main membrane materials, tea polyphenol or vitamin E and other antioxidants are combined, and curcumin is induced to transmembrane-transfer from a lipid bilayer membrane to an internal water phase through precise pH gradient control and mild heating, so that the encapsulation efficiency of curcumin is remarkably improved. Then, through the steps of high-pressure microjet homogenization, low-temperature dialysis and the like, the maqui berry anthocyanin-curcumin compound liposome which is uniform in particle size, high in stability and excellent in encapsulation efficiency is prepared.

The invention discloses a preparation method of food antibacterial preservative paper based on plant essential oil, and the preparation method comprises the following steps: S1, firstly selecting beta-cyclodextrin, dissolving the beta-cyclodextrin in water, and stirring and dissolving under the water bath condition of 65-75 DEG C to obtain a beta-cyclodextrin solution; s2, mixing origanum vulgare essential oil with ethanol to obtain a mixed solution A, and then adding the mixed solution A into the beta-cyclodextrin solution in S1; s3, continuously keeping the mixed solution A under a 65-75 DEG C water bath condition, stirring the solution and mixing to obtain a mixed solution B; s4, standing the mixed solution B, and then removing supernatant liquid under a centrifugal condition to obtain a bottom-layer solid; s5, drying the obtained bottom layer solid to obtain the microcapsule; and S6, mixing the microcapsules and PVA to obtain the preservative paper. The fresh-keeping paper not only can prolong the fresh-keeping period of food during long-distance transportation, but also can prolong the shelf life of the food during sales, is easy to degrade, conforms to the green and environment-friendly packaging concept, and provides a thought for food fresh-keeping.

The application relates to the technical field of lubricating grease, in particular to long-life anti-wear lubricating grease and application of the lubricating grease to automobile motor bearings. The lubricating grease is prepared from raw materials including a composite calcium sulfonate thickener 14-22%, high-alkaline-value synthetic calcium sulfonate 1.5-3.5%, surface-modified nano calcium carbonate 0.3-1.2%, a first anti-wear component 1.2-2.8%, a second anti-wear component 1.5-3.2%, a third anti-wear component 2-4%, a microcapsule component 1-2.5% and a balance of a composite base oil; the first anti-wear component includes modified nano molybdenum disulfide; the second anti-wear component includes lanthanum-doped nano cerium dioxide; the third anti-wear component includes a mixture of molybdenum dialkyldithiocarbamate, sulfided isobutylene and phosphoric acid trimethylphenyl ester; and the composite base oil is a ternary mixture of poly-alpha-olefin, alkylated naphthalene and partial benzene triacid ester. The lubricating grease has long life and anti-wear performance.