The invention provides 1,2,3-thiadiazole-1,3,4-thiadiazole derivatives, and a preparation method and application thereof. The invention relates to 1,2,3-thiadiazole-containing heterocyclic compounds with the chemical structural general formula shown as the specification. The invention discloses the structural general formula of the compounds, a synthesizing method of the compounds, application ofthe compounds serving as pesticides, bactericides, anti-plant-virus agents and plant activating agents, and a process for preparing the pesticides, the bactericides, the anti-plant-virus agents and the plant activating agents by mixing the compounds and agriculturally acceptable adjuvants or synergists. The invention also discloses application of the compounds when the compounds are combined withcommodities of the pesticides, the bactericides, the anti-plant-virus agents and the plant activating agents in prevention and control of agricultural, forestry, horticultural and health diseases, insect pests and virus diseases, and a preparation method of the compounds.