Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
1364 results about "Virus diseases" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
The most common diseases caused by viruses include ebola, influenza, yellow fever, human immunodeficiency virus (HIV / AIDS), human papillomavirus (HPV), viral gastroenteritis, varicella, and viral hepatitis, among others.
Adeno-Associated Virus Virion for Gene Transfer to Nervous System Cells
ActiveUS20130224836A1Improve efficiencyLower Level RequirementsNervous disorderSpecial deliveryNervous systemAdeno associate virus
The present invention provides a means for transferring a therapeutic gene of interest into a nervous system cell by a highly-efficient and simpler means. More specifically, the present invention provides a recombinant vector that uses an adeno-associated virus (AAV), a method for manufacturing the recombinant vector, and a method for using the recombinant vector. More specifically, recombinant adeno-associated virus virions, which are capable of passing through the brain-brain barrier, for transferring a therapeutic genes of interest into a nervous system cell in a highly-efficient manner, a drug composition containing the recombinant adeno-associated virus virions, a method for manufacturing the recombinant adeno-associated virus virions, and a kit or the like are provided.
Owner:JICHI MEDICAL UNIVERSITY
High-neutralizing-activity anti-SARS-CoV-2 fully-humanized monoclonal antibody and application thereof
ActiveCN111303280AGood neutralizing effectReduced responseImmunoglobulins against virusesAntiviralsDiseaseAntiendomysial antibodies
The invention discloses an anti-SARS-CoV-2 fully-humanized monoclonal antibody against SARS-CoV-2. The antibody is obtained by screening through a flow sorting-single cell PCR technology, and has a unique CDR partition. The invention further discloses an application of the antibody in preparation of medicines for treating the 2019-coronavirus disease. The monoclonal antibody disclosed by the invention has efficient and specific anti-SARS-COV-2 activity, also has the characteristics of high expression, complete humanization and good stability, and is suitable for industrial production.
Owner:ACADEMY OF MILITARY MEDICAL SCI
A and C macrocyclic oxidation substituted pentacyclic triterpanoids and preparation method and use thereof
InactiveCN101117348AStrong inhibitory activityOrganic active ingredientsMetabolism disorderDiseaseProstate cancer cell
The present invention relates to a pentacyclic triterpanoid derivative of multiple-oxide substitution of the A ring and the C ring and the medicine salt or solvate of the derivative, and the present invention also relates to the preparation method, the drug combination, and medical use of the derivative. The compound of the present invention has the functions of inhibiting the activity of six human tumor cell strains in vitro, such as human prostate cancer cell (PC-3), nasopharyngeal carcinoma cells (CNE), oral squamous carcinoma cell(KB), human lung cancer cell (A549), human hepatoma cell (BEL-7404), and human cervix cancer cell (Hela), and the function of the invention is at the same magnitude of the positive control of cisplatin, thereby the compound can be used as expected antitumor drug. The compound of the present invention also inhibits the alpha glucosidase strongly, and the inhibiting effect is greater than the positive control of acarbose, thereby the compound can be used as expected medicine for preventing and treating diabetes and the treatment of the virus diseases.
Owner:ZHEJIANG HISUN PHARMA CO LTD
SARS-CoV-2 (severe acute respiratory syndrome-corona virus disease-2) inhibitor and application thereof
InactiveCN111333722AHigh affinityRealize standardized productionBiological material analysisImmunoglobulins against virusesPhage antibodiesAntibody fragments
The invention relates to an SARS-CoV-2 (severe acute respiratory syndrome-corona virus disease-2) inhibitor and application thereof and in particularly relates to a neutralizing antibody for SARS-CoV-2 and application of the neutralizing antibody. According to the antibody, a phage display technology is adopted to construct a high-capacity human immunity phage antibody library, and an SARS-CoV-2 protein is adopted a target, human antibody single-chain antibody fragments are screened, and an antibody with a good neutralizing function on SARS-CoV-2 viruses is obtained. The antibody provided by the invention can be used for treating diseases caused by infection of novel corona viruses, and has significant clinical application value.
Owner:JIANGSU PROVINCIAL CENT FOR DISEASE CONTROL & PREVENTION PUBLIC HEALTH RES INST OF JIANGSU PROVINCE
Silybin esters derivatives and preparation and use thereof
The invention relates to a silibinin monoester derivative and its medicine salt or solvates. The invention also relates to its preparation method and its drug combination and medical application. The compound can inhibit activity of hepatitis b virus, so it is expected to be used as drug to treat hepatitis b virus and relevant virus diseases. The compound can protect liver and is expected to be used as drug preventing liver damage. The compound possesses effect anti free radical and is expected to be used as drug treating diseases caused by free radical.
Owner:ZHEJIANG HISUN PHARMA CO LTD
Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
ActiveUS20110027270A1Reduce in quantityLower titerSsRNA viruses negative-senseVirus peptidesMonoclonal antibodyVirus diseases
Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes. Also provided herein are compositions comprising such antibodies and methods of using such antibodies to diagnose, prevent or treat Influenza virus disease.
Owner:MT SINAI SCHOOL OF MEDICINE
Pesticide composition for relieving phytotoxicity of herbicide
ActiveCN102960341APromote protoplasm flowIncrease vitalityPlant growth regulatorsBiocideVerticillium speciesFreeze injury
The invention relates to a pesticide composition for relieving the phytotoxicity of herbicide. Effective components are a plant growth regulating agent and active polysaccharide, wherein the plant growth regulating agent is any one or a mixed agent of two of compound nitrophenolate and diethylaminoethyl hexanoate; the active polysaccharide is any one or a mixed agent of two of chitosan oligosaccharide and poly-glucosene; and the pesticide composition comprises the effective components in parts by weight of 0.05-90.0 parts of the plant growth regulating agent and 0.05-90.0 parts of the active polysaccharide. The pesticide composition comprehensively utilizes the synergism effect of the plant growth regulating agent and the active polysaccharide to resist disease source force and relieve the phytotoxicity of the herbicide. The pesticide composition is further applicable to crop exogenous damages including hormone phytotoxicity, low-temperature frozen injury, salt alkaline injury and the like, and also can be used for crop diseases of crops virus diseases, verticillium wilts and the like.
Owner:郭红甫
Vaccines expressed in plants
The anti-viral vaccine of the present invention is produced in transgenic plants and then administered through standard vaccine introduction method or through the consumption of the edible portion of those plants. A DNA sequence encoding for the expression of a surface antigen of a viral pathogen is isolated and ligated to a promoter which can regulate the production of the surface antigen in a transgenic plant. This gene is then transferred to plant cells using a procedure that results in its integration into the plant genome, such as through the use of an Agrobacterium tumenfaciens plasmid vector system. Preferably, the foreign gene is expressed in an portion of the plant that is edible by humans or animals. In a preferred procedure, the vaccine is administered through the consumption of the edible plant as food, preferably in the form of a fruit or vegetable juice which can be taken orally.
Owner:PRODI GENE INC
GeXP (Gene Expression Profiler) detection kit for differentiating 11 kinds of duck viral diseases
ActiveCN103773899AStrong specificityImprove throughputMicrobiological testing/measurementDNA/RNA fragmentationDiseaseDuck hepatitis A virus
Owner:GUANGXI VETERINARY RES INST
Method for preventing and treating tomato yellow leaf curl virus diseases
ActiveCN103828582AReduce morbiditySolve quality problemsPlant protectionTomato yellow leaf curl virusGreenhouse
The invention discloses a method for preventing and treating tomato yellow leaf curl virus diseases. The method includes cultivating tomatoes in sunlight greenhouses in large rows and small rows; transplanting abutilon theophrasti 15-20 days before the tomatoes are planted in fields; planting one row of abutilon theophrasti at the planting distances of 20cm along the inner side of the root of a north wall of each greenhouse; planting a row of abutilon theophrasti at the planting distances of 2.0m between each two adjacent small field planting rows; pulling out the abutilon theophrasti among the small field planting rows after fruits of fifth panicles of the tomatoes are set. The row spacing of the large rows of the tomatoes planted in the sunlight greenhouses is 80cm, and the row spacing of the small rows of the tomatoes planted in the sunlight greenhouses is 60cm. The leaf age of the abutilon theophrasti is 4 leaves and 1 core when the abutilon theophrasti is transplanted. The method has the advantages that the incidence of the tomato yellow leaf virus diseases can be effectively reduced, and the incidence of tomato yellow leaf virus disease infected tomato varieties can be within the range of 10% under the control generally.
Owner:QINGDAO GREEN SILICON VALLEY TECH CO LTD
Influenza viruses and uses thereof
ActiveUS20120244183A1Reduced ability to reassortImprove securitySsRNA viruses negative-senseSugar derivativesDiseaseOpen reading frame
Described herein are chimeric influenza virus gene segments and nucleic acid sequences encoding such chimeric influenza virus gene segments. A chimeric influenza virus gene segment described herein comprises packaging signals found in the non-coding and coding regions of one type of influenza virus gene segment and an open reading frame of a different type of influenza virus gene segment or fragment thereof. Also described herein are recombinant influenza viruses comprising two or more chimeric influenza virus gene segments and the use of such viruses in the prevention and / or treatment of influenza virus disease.
Owner:MT SINAI SCHOOL OF MEDICINE
A system for aquiculture using recirculated water based on decline algae
InactiveCN101161061AImprove efficiencyReduce consumptionClimate change adaptationPisciculture and aquariaWater basedLight energy
The invention provides a aquaculture system which uses light energy to realize cycle of water with a media of micro-algae and inhibits the disease occurrence of aquaculture species. The system includes two aquaculture subsystems which are connected through pipes for water cycle of aquaculture. The water-recycled aquaculture system based on micro-algae forms biological cycle chain through reasonable combination of the two aquaculture subsystems to significantly improve the efficiency of aquaculture. The circulating water based on micro-algae transfers surplus nutrient in aquaculture of the first aquatic product to the second aquatic product, and to be used as bait of the second aquatic product. Therefore, the water consumption is reduced and the discharged 'waste' is changed to effective nutrient. The bacteriosis occurrence of aquatic products is inhibited by using natural antibiotics secreted by micro-algae, and in addition, the infection probability of virus diseased is reduced.
Owner:FISHERY MACHINERY & INSTR RES INST CHINESE ACADEMY OF FISHERY SCI
Virus removal and rapid propagation technology of sweet potato variety 'Shangshu 19' and culture material
InactiveCN101611697AImprove immunitySolve the serious sweet potato virus diseaseCultivating equipmentsPlant tissue cultureDiseaseGermplasm
The invention is a virus removal and rapid propagation technology of sweet potato variety 'Shangshu 19', comprising the following steps: selecting plants which are robust without diseases and insect pests and have characteristics of the variety from growing plants; clipping stem with stem tip; removing visible leaves; sterilizing; peeling the stem tip with 1-2 leaf primodia via a dissecting needle; quickly inoculating into a differentiation and induction culture medium; trimming the sterilized seedling into stem segments with 1-2 internode(s) and switching into an enrichment medium after virus detection; selecting sterilized seedling in vigorous growth to cut into small segments with 1-2 internode(s) and switch into a rooting medium; carrying out domestication on seedling after rooting. The invention has stem tip in virus removal and stem segment in rapid propagation, solves the problems of severe virus disease for sweet potato, poor quality of new cultured breed, germplasm degradation, low yield and the like propagated by using sweet potato block and stem. The invention can artificially control the growing conditions, can not be influenced by nature, and has the advantages of small amount of material use, economical culturing materials, short growth cycle, large propagation coefficient and convenient management and is favor of industrial production.
Owner:周玉玲
Green biological water-flush fertilizer
InactiveCN102040431AIncrease productionImprove qualityFertilizer mixturesBiotechnologyContinuous cropping
The invention discloses a green biological water-flush fertilizer, relating to fertilizers. A manufacturing method is as follows: a, adding animal protein powder, vegetable protein powder, complex bacteria and complex enzyme into an amino acid solution, mixing uniformly, placing the mixture under the temperature of 15-35 DEG C, and after 6-8 days, forming a product A; and b, adding a complex nutrition conditioner, a continuous cropping modifier, a biological insect repellant, a harm removing agent, trace elements, a nitrogen-phosphorus-potassium compound fertilizer into the product A, mixing uniformly and obtaining the green biological water-flush fertilizer. The green biological water-flush fertilizer has the beneficial effects that 1, the sprouting rate can be improved, the fast rootingcan be realized, the sufficient nutrition of plants can be ensured, and premature senility resistance and aging resistance are achieved; 2, the yield and the quality of vegetables, melons and fruits are improved; 3, the utilization ratio, the long-term property, fast effect, long effect and stable efficiency of a base fertilizer are improved; 4, the extremely-good inhibiting effect and improving function are achieved for yellow seedlings, runt seedlings, lobules, leaf roll, blight, pythium debaryanum, droop, dead seedling, rot roots, abnormal rotting disease, virus disease, seedling falling disease and the like; and 5, green and unpolluted foods are beneficial to being produced.
Owner:徐贵阁
Ferulic acid and ferulic acid derivative anti-phytoviral agents
ActiveCN102090412AExcellent anti-plant virus activityEffectively prevent and treat viral diseasesBiocideOrganic chemistryNicotiana tabacumTobacco mosaic virus
The invention relates to a ferulic acid shown in a general formula (I) and the application of derivatives thereof to pesticides. When used as novel anti-phytoviral agents, the derivatives can well inhibit tobacco mosaic viruses, pepper viruses, tomato viruses, sweet potato viruses, potato viruses, melon viruses, maize dwarf mosaic viruses and the like, and effectively prevent and control the virus diseases of various crops such as tobacco, peppers, tomatoes, melons, grains, vegetables, beans and the like, and are particularly suitable for preventing and controlling tobacco mosaic. Meanings of each group are shown in specifications.
Owner:NANKAI UNIV
Nucleic acid detection kits
InactiveUS20050158716A1Quick checkQuick identificationSugar derivativesMicrobiological testing/measurementMicroorganismNucleic acid detection
The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5′ nucleases and 3′ exonucleases, are used to detect and identify nucleic acids derived from microorganisms. Methods are provided which allow for the detection and identification of bacterial and viral pathogens in a sample.
Owner:THIRD WAVE TECH
O-formammidotiazol-benzamide derivatives based on ryanodine receptor, and preparation method and applications thereof
The invention provides o-formammidotiazol-benzamide derivatives, and a preparation method and applications thereof. The o-formammidotiazol-benzamide derivatives have the chemical structure general formula represented by the formula I or the formula II. The invention discloses the structure general formula of the compounds, the synthesis method and the applications of the compounds as insecticides, acaricides and bactericides; the compounds are mixed with agriculturally acceptable auxiliary agents or synergistic agents for use in processing crafts of preparing the insecticides, the acaricides and the bactericides. The invention also discloses the applications of the compounds in combination with the commercial insecticides, the acaricides, the bactericides, anti-plant virus agents and plant activators for prevention and treatment of agriculture, forestry, horticulture plant diseases, insect attacks, acarus attacks and virus diseases, and the preparation method of the compounds.
Owner:JIANGXI TIANREN ECOLOGY
Anti-plant virus pesticide composition
The invention provides a pesticide composition, and in particular relates to an active pesticide composition, compounding one or more of toxic fluoride phosphate, the weight ratio of toxic fluoride phosphate to other active substances is 30:0.15 to 3.3:30, and the content of effective components by weight is 1%-90%. The compound composition can be processed into water dispersible powder, suspending agent, microemulsion, aqueous emulsion, water dispersible granule, dry suspension emulsion and seed coating agent and the like, after accessory ingredient or carrying agent is added. The composition can be used to prevent and treat virus diseases caused by rice stripe virus, rice dwarf virus, maze rough dwarf virus, rice black-streaked dwarf virus, tomato virus, cucumber mosaic virus and tobacco mosaic virus, and has the beneficial effects of enhanced effect, concurrent treatment, postponed pesticide resistance, decreased dosage of toxic fluoride phosphate and reduced cost.
Owner:GAUNGXI TIANYUAN BIOCHEM
Vaccines for use in the prophylaxis and treatment of influenza virus disease
ActiveUS20130209499A1Promote multimerizationEasy to purifySsRNA viruses negative-senseBacteriaHemagglutininInfluenza virus A hemagglutinin
Provided herein are polypeptides comprising portions of the influenza virus hemagglutinin, compositions comprising such polypeptides that can be used as immunogens in vaccines and methods of their use to generate an immune response against multiple influenza subtypes in a subject.
Owner:MT SINAI SCHOOL OF MEDICINE
Method for cultivating detoxification tissue culture bulb of fritillaria thunbergii
InactiveCN101213937ANo existenceControl spreadCultivating equipmentsHorticulture methodsMultiplication rateFritillaria thunbergii
The present invention relates to a culture method for the detoxication and the tissue culture of the bulb of Fritillaria thunbergii, which belongs to the technical field of breeding the plant seedling and is specially used for breeding the detoxic seedling of Fritillaria thunbergii and the detection of the virus of Fritillaria thunbergii. The method comprises the steps such as the formulation of the culture medium, the culture of the detoxication tissue culture bulb, the detection of the virus ELISA, etc. The present invention has good detoxication effect, high sensitivity of the virus detection, and can guarantee that the detocication daughter bulb is free from virus, thereby effectively controlling the occurrence and the broadcasting of the virus disease; the multiplication of the bulb is fast, and the monthly multiplication rate can reach 4.5 times, thereby being applicable to the factory seedling raising, greatly saving the breeding land of the traditional method and obviously reducing the production cost of Fritillaria thunbergii; the present invention can be applied to the purification and rejuvenation and the development of the species of Fritillaria thunbergii.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES
Lignin derivatives as well as preparation method and use thereof
The invention provides lignin derivatives as well as a preparation method and use thereof. The invention relates to compounds containing lignin, and the compounds have a chemical structure general formula represented by a formula I. The invention discloses a structural general formula and a synthetic method of the compounds, application of the compounds used as an antiviral agent and a bactericide, and a processing technology for preparing the antiviral agent and the bactericide by mixing the compounds with agriculturally acceptable auxiliaries or synergists. The invention further discloses application of the compounds in preventing and treating diseases, insect attack, mite attack and virus diseases in agriculture, forestry and horticulture in combination with an insecticide, a miticide, a bactericide, acetylglucosyl bromide and a plant activator and preparation methods of the compounds. The invention further discloses antineoplastic activity of the compounds and application thereof in treating tumors.
Owner:NANKAI UNIV
Polyinosinic powder for livestock and preparation method thereof
The invention aims to provide veterinary polyinosinic powder which mainly comprises poly cytidine acid, poly inosinic acid and auxiliary material, is prepared through a series of processes, such as mixing, dissolving, granulating, drying, grinding and the like, and is mainly used to prevent and treat the virus diseases of the livestock. Through the clinical therapeutic effect test we find that the medicine is characterized by good therapeutic effect, little dosage and high efficiency in preventing and treating the virus diseases of the livestock, and is suitable to be popularized and applied in the livestock industry.
Owner:TIANJIN RINGPU BIO TECH
Animal-free cell culture method
InactiveUS20060183224A1Easy to replaceSsRNA viruses positive-senseCell culture mediaBiotechnologyCell culture media
The present invention relates to a process for animal, preferably human, diploid anchorage-dependent cell culture, in the absence of exogenous components of primary animal origin, and to a cell culture medium substantially free of exogenous components of primary animal origin suitable for carrying out said process. In particular the invention concerns a cell culture medium which comprises at least one, more preferably several, exogenous animal-free growth factors. The present invention also relates to a process for cultivating animal, preferably human diploid anchorage-dependent cells in a medium according to the invention, involving the use of a trypsin substitute of non-animal origin for passaging cells. The invention further relates to a process for producing viruses, viral vaccines and the like.
Owner:GLAXOSMITHKLINE BIOLOGICALS SA
Cleavage of nucleic acids
InactiveUS20060035256A1Rapid detection and identificationHydrolasesPeptide/protein ingredientsMicroorganismNucleic acid cleavage
The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5′ nucleases and 3′ exonucleases, are used to detect and identify nucleic acids derived from microorganisms. Methods are provided which allow for the detection and identification of bacterial and viral pathogens in a sample.
Owner:THIRD WAVE TECH
Composite of toxic fluoride phosphate and plant growth regulator
ActiveCN102388918AEfficient prevention and controlInhibit expansionPlant growth regulatorsBiocidePhosphateTobacco mosaic virus
The invention provides a formulation composite comprising toxic fluoride phosphate and at least one growth regulator. According to the weight part, the toxic fluoride phosphate accounts for 10%-80% of the formulation composite, the growth regulator accounts for 0.0001%-2% of the formulation composite, the formulation composite also comprises an assistant, an surface active agent, a solvent and a carrier accepted by agriculture, and the formulation composite can be prepared into wettable powder, suspending agent, missible oil, microemulsion, emulsion in water, water dispersible granule, dry suspending agent, seed coating agent and other agents. The formulation composite can be used for preventing and curing tobacco mosaic virus, cucumber mosaic virus, and various virus diseases caused by viruses on rice, such as tobacco mosaic, cucumber mosaic, tomato virus disease, pepper virus disease, rice virus disease and the like and achieves the effects of improving efficacy, treating in a compatible manner, delaying medicine resistance, reducing the using amount of toxic fluoride phosphate and the like.
Owner:GAUNGXI TIANYUAN BIOCHEM
Root restriction culture method for preventing passion fruit base rot disease
ActiveCN107535247AEarly floweringGuarantee the basic needs of nutrition during the reproductive periodCultivating equipmentsPlant protectionDiseasePlant cultivation
The invention discloses a root restriction culture method for preventing the passion fruit base rot disease, and belongs to the field of plant cultivation. The method comprises the following steps ofvirus-free seedling selection, substrate preparation, canopy frame construction, planting vessel installation and current year cultivation and management. By selecting virus-free seedlings for planting, a special substrate, a special planting vessel and a reasonable biennial culture mode are prepared for solving the passion fruit virus disease from the source, the problem of the passion fruit baserot disease in the planting process is solved, the effect of preventing and treating bacterium breeding is achieved, and the requirement for growth environment needed by passion fruit planting is met. Passion fruit virus disease spreading can be controlled, the base rot disease outbreak tendency can be controlled, and the purposes of high efficiency and high production of passion fruit are achieved.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI
Honeysuckle composition for resisting virus diseases of pigs
The invention discloses a honeysuckle composition for resisting virus diseases of pigs, and relates to a feed additive or Chinese veterinary medicine special for preventing and controlling the virus diseases of the pigs and capable of promoting the growth of the pigs. The composition consists of the following components: 30 to 60 portions of honeysuckle extract, 5 to 20 portions of Chinese thorowax root extract, 5 to 20 portions of baical skullcap root P.E, 5 to 20 portions of dandelion P.E, and 10 to 25 portions of licorice extract. The composition is Chinese medicinal powder of which the granularity is between 200 and 300 meshes and which is yellow or brown-yellow, and has the following content of the active components: 5 to 20 percent of chlorogenic acid, 2 to 10 percent of baicalin and5 to 15 percent of glycyrrhizic acid. When used, the composition is mixed with a feed in a ratio of 0.02-0.2 percent and then is fed to animals. The composition has the effect of preventing and controlling highly pathogenic blue ear pig disease, porcine rotavirus disease, influenza, infectious bronchitis and the like, and virus diseases caused by porcine circovirus PCV, foot-and-mouth disease virus and the like, and can effectively promote the growth of the live pigs.
Owner:新乡博凯生物技术有限公司
Novel coronavirus antigen epitope and application thereof
ActiveCN111848753AImproving immunogenicityHigh titerSsRNA viruses positive-senseAntibody mimetics/scaffoldsAntigen epitopeCoronavirus vaccination
The invention provides a novel coronavirus antigen epitope and application thereof. A super computer is used for simulating S, E, M and N protein structures of the novel coronavirus, and novel coronavirus epitopes SEQ ID NO 1-38 are obtained through calculation. The epitopes have very good immunogenicity; an antibody generated by inducing a part of epitope polypeptide has the effect of neutralizing the novel coronavirus; the antigen epitope can be combined with antibodies in serum of novel coronavirus patients at home and abroad, has the potential of resisting various novel coronavirus strains, and also has the potential of identifying and applying different strains. The epitope provided by the invention can be used for (1) research and development of novel coronavirus vaccines and universal coronavirus vaccines such as MERS viruses and SARS viruses; and (2) preparing a novel coronavirus antibody, and further detecting and typing viruses and treating diseases caused by the viruses. Thenovel coronavirus antigen epitope has a wide application prospect in the aspects of prevention of coronavirus and propagation and outbreak thereof, and detection and diagnosis of virus strains.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI
Fusion protein of SARS-CoV-2, and vaccine composition of fusion protein
InactiveCN111662389AInhibition of replicationRefrain from rebroadcastingSsRNA viruses positive-senseAntibody mimetics/scaffoldsSpecific immunityVariant strain
The invention belongs to the technical field of biology, and particularly relates to a fusion protein of SARS-CoV-2, and a vaccine composition of the fusion protein. The fusion protein and the prepared vaccine composition containing the fusion protein overcome the defects of poor immunogenicity and the like of subunit vaccines, can induce the specific immune response aiming at SARS-CoV-2, and achieve the purposes of inhibiting the replication of SARS-CoV-2, inhibiting the spread of SARS-CoV-2 or preventing the settlement of SARS-CoV-2 common strains and variant strains in SARS-CoV-2 host bodies. The fusion protein and the vaccine composition containing the fusion protein can effectively prevent and / or treat novel coronavirus pneumonia (Corona Virus Disease 2019, COVID-19). The fusion protein can be recombined and expressed in large quantities by the aid of the genetic engineering technology, the consumed time is short, and the large-scale production can be facilitated.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
1,2,3-thiadiazole-1,3,4-thiadiazole compounds and preparation method and application thereof
InactiveCN102174031AHave anti-disease activityHas growth regulating activityBiocideOrganic chemistryDiseaseAdjuvant
The invention provides 1,2,3-thiadiazole-1,3,4-thiadiazole derivatives, and a preparation method and application thereof. The invention relates to 1,2,3-thiadiazole-containing heterocyclic compounds with the chemical structural general formula shown as the specification. The invention discloses the structural general formula of the compounds, a synthesizing method of the compounds, application ofthe compounds serving as pesticides, bactericides, anti-plant-virus agents and plant activating agents, and a process for preparing the pesticides, the bactericides, the anti-plant-virus agents and the plant activating agents by mixing the compounds and agriculturally acceptable adjuvants or synergists. The invention also discloses application of the compounds when the compounds are combined withcommodities of the pesticides, the bactericides, the anti-plant-virus agents and the plant activating agents in prevention and control of agricultural, forestry, horticultural and health diseases, insect pests and virus diseases, and a preparation method of the compounds.
Owner:NANKAI UNIV
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com