45 results about "Polyhexamethylene guanidine" patented technology

The invention provides a compound disinfectant for preventing and treating aquaculture virus diseases and a preparation method thereof. The composite disinfectant is prepared by introducing polyhexamethylene guanidine or a salt thereof, a quaternary ammonium salt compound, metal nanoparticles and an auxiliary agent into a water system as main raw materials, and is prepared by the following steps: adding a quaternary ammonium salt compound solution and a penetrating agent into a polyhexamethylene guanidine or salt solution thereof, and uniformly stirring and mixing to obtain a mixed solution A; slowly dropwise adding the metal nanoparticle dispersion liquid into the mixed solution A, starting ultrasonic treatment at the same time, and uniformly stirring and mixing to obtain a mixed solution B; dropwise adding the pH regulator solution into the mixed solution B, regulating the pH, adding the preservative solution, supplementing water, uniformly mixing, standing and curing to obtain the composite disinfectant. The compound disinfectant aims at achieving synergistic interaction, finally achieves the comprehensive prevention and treatment effects of being efficient, low in toxicity, broad in spectrum and not prone to inducing drug resistance, and particularly achieves efficient and safe prevention and control on fish, shrimp and crab virus diseases so as to meet the urgent requirement for healthy aquaculture.

The invention provides dust-free antibacterial deodorant bentonite cat litter and a preparation method thereof, and belongs to the technical field of cat litter. Firstly, a certain amount of sodium bentonite, baking soda and calcium carbonate are used for preparing bentonite cat litter, then polyvinyl alcohol and sodium carboxymethyl cellulose which have the film forming property, polyhexamethylene guanidine hydrochloride which has the bactericidal property and soybean ethyl sulfate morpholine which has the deodorization function are used for preparing the bentonite cat litter; the components are compounded to obtain a functional dust suppressant with antibacterial, deodorant and film-forming effects, the functional dust suppressant is sprayed and coated on the surface layer of the bentonite cat litter, so that the prepared dust-free antibacterial and deodorant bentonite cat litter is remarkable in deodorant and antibacterial effects and good in wear resistance, and a layer of water-soluble film is formed on the surface of the dust suppressant after the functional dust suppressant is sprayed for dust suppression treatment, so that the dust suppression effect is good. The bentonite cat litter has the advantages that the structure and the film-forming property of the surface layer of the bentonite cat litter are improved, the hardness and the wear resistance of the surface are improved, the dust suppression effect of the cat litter is obviously improved, dust is extremely low under simulated falling and transportation conditions, and the cat litter has excellent water absorption and caking performance.

The present invention relates to the field of fabric technology, and discloses an antibacterial and deodorizing nylon fabric and a preparation method thereof. The preparation method of the antibacterial and deodorizing nylon fabric comprises the following steps: reacting mercaptoethylamine with eugenol to obtain an intermediate product; modifying nano-titanium dioxide with a silane coupling agent KH560 and the intermediate product in sequence, and then mixing with nylon 56, ethylene-methyl acrylate-glycidyl methacrylate terpolymer, and polyhexamethylene guanidine; co-extruding, pelletizing, and melt spinning to obtain modified bio-based nylon 56 filaments; soaking the modified bio-based nylon 56 filaments in a polyacrylic acid / water solution and weaving them into bio-based nylon 56 fabric; and treating the bio-based nylon 56 fabric with an antibacterial and deodorizing finishing solution to obtain the antibacterial and deodorizing nylon fabric. The antibacterial and deodorizing nylon fabric of the present invention has excellent antibacterial and deodorizing properties and washability.

The invention discloses an antibacterial modified lyocell fiber fabric and a preparation method thereof, and the preparation method comprises the following steps: cutting a lyocell fiber fabric into a certain size, and placing the cut lyocell fiber fabric in a eutectic solvent for pretreatment; and after the pretreatment is finished, adding an antibacterial agent into the deep-eutectic solvent, then adding a coupling agent, carrying out graft modification, after the reaction is finished, taking out, washing with deionized water, and finally drying to obtain the antibacterial modified lyocell fiber fabric. According to the method, the lyocell fiber fabric is used as a reaction raw material, polyhexamethylene guanidine hydrochloride is used as an antibacterial agent, glutaraldehyde is used as a coupling agent, a choline chloride-urea eutectic solvent is used as a pretreatment solvent and a subsequent reaction medium, the lyocell fiber fabric is pretreated in the eutectic solvent, the fiber surface is damaged, more active hydroxyl groups are exposed, and the surface of the fiber is subjected to surface modification; and adding a coupling agent and an antibacterial agent, so that the polyhexamethylene guanidine hydrochloride is grafted on the lyocell fiber fabric, and the antibacterial lyocell fiber fabric which is excellent in antibacterial performance, long-acting and washable is obtained.

The invention relates to a veterinary hoof disease prevention and treatment composition as well as a preparation method and application thereof, and aims to solve the technical problems that existing commercial hoof bath lotion is limited in sterilization effect and relatively strong in local irritation, and a safe and efficient treatment medicament for treating cow hoof warts is lacked and the like. The invention provides a veterinary composition which comprises the following active ingredients: a glycyrrhizic acid compound, didecyl methyl ammonium bromide and polyhexamethylene guanidine salt, and the three components are combined, so that the composition has an antibacterial effect and an effect of promoting skin tissue repair at the same time. A series of tests prove that the traditional Chinese medicine composition can effectively inhibit animal pathogenic bacteria, prevent and / or treat animal limb and foot diseases and promote healing and repairing of ulcer injury. The medicament disclosed by the invention is suitable for preventing and treating limb and hoof diseases in a large-scale pasture, has the characteristics of high sterilization efficiency, good safety and effective treatment, and can improve the animal hoof health management level.

Disclosed herein is a composition that contains a polyhexamethylene guanidine salt and a thermoplastic polymer. The polyhexamethylene guanidine salt is grafted to the thermoplastic polymer. The present invention also relates to a method of forming the composition and to a mixture that can be beneficially employed to form the composition. The present invention also relates to medical devices comprising or consisting of said composition or from said mixture.

The invention relates to the technical field of textile fabrics, in particular to a preparation method of a bio-based flame-retardant antibacterial textile fabric, which comprises the following steps: step 1, cleaning the textile fabric and then drying for later use; 2, sequentially preparing a solution A, a solution B and a solution C; wherein the solution A is a poly dimethyl diallyl ammonium chloride aqueous solution with the mass fraction of 3-7%; the solution B is a nucleotide salt flame retardant aqueous solution with the mass fraction of 15-30%; the solution C is a polyhexamethylene guanidine salt antibacterial agent aqueous solution with the mass fraction of 4-9%; 3, the standby textile fabric in the step 1 is sequentially subjected to A solution dipping, B solution dipping, C solution dipping and B solution dipping to form a cycle, roll compacting is conducted after each time of dipping till the pick-up rate is 90-100%, and the total number of cycles is 3-7; and drying the textile fabric to obtain the bio-based flame-retardant antibacterial textile fabric.

The invention belongs to the technical field of medical materials, and discloses antibacterial silica gel as well as a preparation method and application thereof. The antibacterial silica gel comprises a silica gel substrate and a copolymer coating on the surface of the silica gel substrate, the copolymer coating is grafted with polyhexamethylene guanidine biguanide; and the copolymer coating comprises an isooctyl acrylate structure and a maleic anhydride structure. The antibacterial silica gel provided by the invention has good antibacterial performance, and further has high tensile strength and tear strength.

The invention belongs to the field of polymer separation membranes, and particularly discloses a hydrophilic antibacterial oil-water separation polyphenylene sulfide membrane material and a preparation method and application thereof, and the preparation method comprises the following steps: (S1) preparing a PPS microporous membrane by a thermally induced phase separation method; (S2) treating the PPS microporous membrane in a dilute nitric acid solution to obtain a nitric acid modified hPPS microporous membrane; (S3) dispersing CNF in water to obtain a CNF dispersion liquid; coating the surface of the hPPS membrane with the CNF dispersion liquid in a suction filtration deposition manner, and dipping the hPPS membrane in a solution containing Fe < 3 + > to obtain a CNF-hPPS membrane; and (S4) dipping the CNF-hPPS in a (hexamethyleneguanidine) hydrochloride solution to obtain the hydrophilic antibacterial oil-water separation polyphenylene sulfide membrane material. The polyphenylene sulfide micro (PPS) porous membrane is prepared by adopting a thermally induced phase separation method, and after acidizing treatment, cellulose nanofiber (CNF) and polyhexamethylene guanidine (PHMG) with specific content are combined in an ion complexing manner, so that the oil-water separation rate and antibacterial effect of the membrane are greatly improved under the condition of lower loss of membrane flux.

The application discloses a preparation method of an anti-algae-adhesion super-hydrophobic composite coating. The method comprises the following steps: uniformly dispersing epoxy resin into ester substances to obtain a mixed solution A; adding polyhexamethylene guanidine hydrochloride, polyvinylpyrrolidone, nano-TiO2, polytetrafluoroethylene micro powder, graphene oxide and gamma-aminopropyl triethoxysilane into the mixed solution A, uniformly mixing to obtain a mixed solution B; adding fluorine-containing silane and polyether amine curing agent into the mixed solution B, uniformly dispersing to obtain a mixed solution C; and spraying the mixed solution C to a substrate surface, and performing normal-temperature ventilation and drying to obtain the super-hydrophobic composite coating. The super-hydrophobic coating prepared by the method has the characteristics of low contact area with water, low viscous force and self-cleaning, and also has good anti-algae-adhesion performance, and has a wide application prospect in marine antifouling.

The invention discloses a flame-retardant antibacterial colored sea-island fiber and a preparation method thereof. The method comprises the following steps: firstly, carrying out ball-milling nanocrystallization pretreatment on an inorganic dye; melting and blending a nano inorganic dye, the dried polyethylene glycol terephthalate slices, a decabromodiphenyl ethane flame retardant and a polyhexamethylene guanidine antibacterial agent in proportion to prepare multifunctional master batches; then, mixing and granulating the master batch and polyethylene glycol terephthalate slices to obtain island component slices; and finally, by taking the slices as island components and soluble polyethylene glycol terephthalate as a sea component, carrying out sea-island composite spinning, stretching and heat setting to obtain the finished fiber. Through the nanocrystallization and two-step dispersion process, the problem that multiple functional components are uniformly dispersed in polyethylene glycol terephthalate is solved, and the obtained fiber is uniform in color and luster, high in color fastness, excellent in lasting flame retardance and antibacterial performance, excellent in comprehensive quality and suitable for the field of high-end functional textiles.

The invention relates to the technical field of flame retardance and antibiosis, in particular to a flame-retardant and antibacterial finishing agent for cotton and preparation and application of the flame-retardant and antibacterial finishing agent. The preparation method comprises the following steps: firstly, dissolving polyhexamethylene guanidine hydrochloride and an epoxy compound, uniformly mixing, reacting, and post-treating to obtain a first intermediate; uniformly mixing the first intermediate with phosphoric acid in an inert atmosphere, and reacting to obtain a second intermediate; and finally, uniformly mixing the second intermediate with urea in an inert atmosphere, and reacting to obtain the flame-retardant antibacterial finishing agent for cotton. According to the flame-retardant antibacterial finishing agent for cotton provided by the invention, on the basis that the excellent bactericidal property of guanidine hydrochloride is fully exerted, the ammonium phosphate group enables cotton fabrics to be more easily dehydrated and carbonized, the cotton fabrics are endowed with excellent flame-retardant property, and the finishing agent has the advantage of washing resistance due to the formation of phosphate bonds.

Disclosed are a modified polyvinyl alcohol starch film and a preparation method. The raw material for preparing the film includes, in a weight proportion, 30-120 parts by weight of starch, 60-100 parts polyvinyl alcohol, 10-30 parts plasticizer, 0.1-20 parts modified aluminosilicate crystals, 0.5-10 parts processing aids, 0.1-10 parts polyhexamethylene guanidine hydrochloride, and 0.01-0.2 parts hydroxy ethyl methacrylate. The modified polyvinyl alcohol starch film can be better prepared utilizing the modified polyvinyl alcohol starch film and preparation method disclosed herein. Polyvinyl alcohol starch itself is a hygroscopic material and can absorb moisture in the air which becomes slimy. In weather with extremely high ambient humidity such as during damp seasons, such film may even directly dissolve, causing the contents to leak. The modified polyvinyl alcohol starch film prepared as disclosed herein is water-resistant and is not susceptible to moisture absorption and exudation due to the influence of ambient temperature and humidity.

This invention relates to the field of functional coating technology, and discloses a long-lasting antifouling polyvinyl alcohol film, its preparation method, and its application. The preparation includes the following steps: Step 1, dissolving an antibacterial agent and a polysaccharide in a solvent and reacting at room temperature for 10-48 hours, followed by dialysis to obtain an antibacterial powder; then mixing the antibacterial powder and dopamine in a solvent for polymerization, and dialysis the reaction solution to obtain a modified antibacterial agent; Step 2, dissolving the modified antibacterial agent and polyvinyl alcohol in a solvent, mixing, and coating the mixture onto a substrate to obtain the polyvinyl alcohol film; the antibacterial agent is polyhexamethylene guanidine and / or polyethyleneimine; the polysaccharide is oxidized dextran or oxidized hyaluronic acid. This invention utilizes the excellent film-forming properties and abundant hydroxyl functional groups of polyvinyl alcohol, using dopamine as a linker to form hydrogen bonds with various antibacterial agents and polysaccharides, thus subjecting the antibacterial agents to more chemical bond constraints and limiting their release rate, thereby achieving long-lasting antifouling effect of the film.

The invention provides a mixture containing microcapsules, a preparation method of the mixture and a nursing pad, and belongs to the technical field of medical monitoring nursing materials. Methyl red and bromothymol blue in the microcapsule-containing mixture provided by the invention are acid-base indicators, so that the nursing pad has a pH value indication effect; the persimmon extract has antibacterial and deodorizing effects; the polyhexamethylene guanidine has a broad-spectrum antibacterial effect; the polyethylene glycol has good solubility, lubricity, moisture retention and the like, so that the solubility, the stability and the bioavailability of the raw materials are improved; part of substances (methyl red, bromothymol blue, persimmon extract, polyhexamethylene guanidine and polyethylene glycol) in the raw materials can be contained in hydrophobic cavities of cyclodextrine to form a microcapsule structure, so that the stability and dispersity of the raw materials are improved, slow and continuous release is realized, the nursing pad has long-time antibacterial and deodorant effects, and the service life of the nursing pad is prolonged. And the color developing uniformity of the nursing pad can be improved.

The invention provides a reactive dye salt-free dyeing method for a cotton fabric by means of oxygen bleaching, aims to integrate a desizing-scouring-bleaching process and a cationization modification process, and comprises the steps of desizing-scouring-bleaching, low-temperature activation oxygen bleaching, cationic solution dipping, dyeing and the like. A traditional oxygen bleaching process and a hydrogen peroxide-tetraacetylethylenediamine low-temperature oxidation process are combined, firstly, the raw cotton fabric is selectively oxidized, selective conversion from hydroxyl to carbonyl on the surface of cotton fiber is achieved, and meanwhile desizing, boiling-off and bleaching are conducted on the raw cotton fabric; subsequently, the oxidized carbonyl-containing cotton fabric and a polyhexamethylene guanidine hydrochloride aqueous solution are subjected to a Schiff base reaction, and cationic groups are successfully introduced to the surface of the cotton fiber, so that the dye-uptake rate and fixation rate of salt-free dyeing of the reactive dye are improved, and the modified cotton fabric is endowed with excellent mechanical strength and whiteness on the basis of the dye-uptake rate and fixation rate.

The invention discloses a breathable thermal fabric and a preparation method thereof, and relates to the field of fabrics. When the breathable warm-keeping fabric is prepared, flax short fibers are oxidized and then sequentially grafted with polyhexamethylene guanidine hydrochloride and maleic anhydride to obtain flax strips; the preparation method comprises the following steps: reacting pentaerythritol with phosphorus oxychloride, and grafting 2-(allyloxy)-4, 6-dichloro-1, 3, 5-triazine to obtain a flame retardant; uniformly mixing terephthalic acid, itaconic acid, ethylene glycol, a flame retardant and dimethyl allyl silane, reacting, and spinning to obtain a hollow polyester strip; and gilling and spinning the flax strips and the hollow polyester strips, and then finishing with dimethyl allyl silane to obtain the breathable warm-keeping fabric. The breathable and warm-keeping fabric prepared by the invention has excellent breathable, warm-keeping, antibacterial, flame-retardant, crease-resistant and mechanical properties.

The application provides a composite oilfield anti-hydrogen sulfide bactericide as well as a preparation method and application thereof. The anti-hydrogen sulfide bactericide comprises component A and component B. The component A is a bactericidal component, and the component B is an anti-hydrogen sulfide agent. The mass ratio of the component A to the component B is (1-2):(1-3). The dodecyl dimethyl benzyl ammonium chloride absorbs the cation of the ionized bacteria body, and is gathered on the cell wall to produce a room blocking effect on TGB and FB. The polyhexamethylene guanidine hydrochloride compensates for the problem that the bactericidal effect of the dodecyl dimethyl benzyl ammonium chloride on SRB is not ideal through adsorption and smothering, so that the harmful bacteria such as SRB, TGB and FB in produced water can be effectively killed. The 1,3,5-tris(hydroxyethyl)-hexahydro-sym-triazine can react with hydrogen sulfide in the produced water, and the sulfur element is bound by chemical bond to effectively reduce the hydrogen sulfide content in the produced water.

The invention relates to the field of high polymer materials, in particular to a municipal pipeline prepared from a PE recycled material and a preparation method. The modified PE material is prepared from 75-86% of a PE reclaimed material, 3-5% of a processing aid, 10-20% of a modifier and the balance of a processing aid, the modifier is prepared from a benzene ring-containing polymer, crosslinked polyethylene, phosphorylcholine, polyhexamethylene guanidine hydrochloride, environment-friendly arginine and a compatilizer according to the weight ratio of (4 to 24) to (4 to 16) to (0.4 to 2) to 1 to (1 to 2) to (1 to 2). The benzene ring-containing polymer, the crosslinked polyethylene, the phosphorylcholine, the polyhexamethylene guanidine hydrochloride, the environment-friendly arginine and the compatilizer can achieve a synergistic effect, so that the anti-fouling and antibacterial properties of the PE recycled material regeneration pipeline can be improved, and meanwhile, the physical properties and the thermal stability of the PE recycled material regeneration pipeline are further improved, so that the PE recycled material regeneration pipeline can keep better properties in a high-temperature and oil-stain environment for a long time; oil stain retention is avoided, and bacterium breeding of the pipeline is reduced.

The invention relates to the field of materials, in particular to a functional material containing nano silicon carbide and a preparation process of the functional material. The functional material containing nano silicon carbide is prepared by taking polyvinyl chloride, polycarbonate, polyethylene, modified nano silicon dioxide, catechin graft and the like as main raw materials and talcum powder, a lubricant and the like as auxiliary materials through melt extrusion. Wherein the nano silicon carbide is wrapped by a polymer, so that the nano silicon carbide has better mechanical properties. In the catechin graft, after polyhexamethylene guanidine hydrochloride is grafted on the surface of catechin, the catechin is not easy to oxidize, so that the antibacterial effect is more remarkable, finally, the functional material containing the nano silicon carbide is prepared through melt extrusion granulation with polyvinyl chloride, polycarbonate, polyethylene and the like, and the prepared functional material containing the nano silicon carbide has antibacterial property and excellent mechanical property.

The present application relates to the technical field of textile fibers, in particular to an antibacterial polyolefin elastomer fiber and a preparation method thereof, the preparation method being: mixing and granulating antibacterial polyolefin elastomer materials to obtain spinning granules; the antibacterial polyolefin elastomer materials comprising ethylene-propylene copolymer A, maleic anhydride grafted ethylene-octene copolymer B and antibacterial agent C; the antibacterial agent C comprising hydroxyl modified nano-silver, polyhexamethylene guanidine hydrochloride and silane coupling agent; and the spinning granules being subjected to melt spinning to obtain the antibacterial polyolefin elastomer fiber. The antibacterial polyolefin elastomer fiber has broad-spectrum antibacterial property, and the fiber has good mechanical properties and elasticity, and the spinning process is smooth, being suitable for industrial application. The present application has simple process, low cost and green environmental protection, and the prepared antibacterial polyolefin elastomer fiber can be applied to various scenes such as antibacterial close-to-body textiles, medical protection, baby products and the like.

The application relates to the technical field of polyurethane sponges, in particular to a polyurethane sponge for shoe materials and a preparation method thereof, the polyurethane sponge for shoe materials comprises the following raw materials in percentage by weight: a foaming agent 0.5-0.7%, toluene diisocyanate 14-16%, silicon oil 0.5-0.7%, triethylene diamine 0.4-0.6%, a tin catalyst 0.08-0.12%, an antibacterial agent 0.8-0.12%, a dispersing agent 3-5%, and the balance is polyether polyol; the antibacterial agent is prepared by the reaction of polyhexamethylene guanidine hydrochloride and a carboxyl-terminated hyperbranched polyester, and then the reaction with zinc ions and calcium ions; the polyurethane sponge has the advantages of improved antibacterial property.

The invention discloses an antibacterial and moth-proof wool yarn fabric and a preparation method thereof. The preparation method comprises pre-treating wool yarn with low-temperature plasma; preparing a modified arginine M-Arg antibacterial agent; compounding the modified arginine M-Arg antibacterial agent with polyhexamethyleneguanidine (PHMG) to obtain an antibacterial solution; placing the pretreated wool yarn in the compounded antibacterial solution to obtain the antibacterial wool yarn by an impregnation method; placing the antibacterial wool yarn in a zinc acetate solution, and in-situ synthesizing N-ZnO nanoparticles on the surface of the antibacterial wool yarn by an ultrasonic method to obtain the antibacterial and moth-proof wool yarn; during the ultrasonic process, adding ammonia water to adjust the pH; and weaving the wool yarn into a wool fabric. The raw materials of the invention are easily available and the cost is low. The problem that wool fabric has poor antibacterial performance and is easily moth-eaten is solved, and the obtained fabric has good antibacterial and moth-proof performance.

The invention discloses a packaging film as well as a preparation method and application thereof, and belongs to the technical field of packaging. The preparation method comprises a carboxylated starch preparation step, a starch / polyhexamethylene guanidine / rutin preparation step and a degradable packaging film preparation step. The preparation method specifically comprises the following steps: by taking starch as a film-forming material, performing carboxylation treatment on the starch to prepare carboxylated starch; the preparation method comprises the following steps: performing cross-linking grafting reaction on carboxylated starch and polyhexamethylene guanidine to obtain starch / polyhexamethylene guanidine, reacting the starch / polyhexamethylene guanidine with rutin, and performing hydrogen bond connection to obtain starch / polyhexamethylene guanidine / rutin. The starch food packaging film is applied to food packaging, the problems that an existing starch food packaging film does not have antibacterial performance and is poor in oxidation resistance are solved, and the packaging film has excellent antibacterial and antioxidant functions.

The invention relates to a modified polyhexamethylene guanidine polymer plastic and a preparation method thereof, and belongs to the technical field of polymer materials. According to the invention, the heat-resistant agent is self-made and is used for modifying polyethylene, and the modified polyethylene and the modified polyhexamethylene guanidine are compounded to obtain the antibacterial high-molecular plastic; the phosphate group of the heat-resistant agent can inhibit gas-phase combustion, enhance the flame retardance of the plastic, increase the crosslinking density of modified polyethylene, and improve the high temperature resistance and mechanical properties of the plastic; according to the modified polyhexamethylene guanidine, the number of active sites on the surface of the polyhexamethylene guanidine is increased through plasma treatment, then the antibacterial ability of the modified polyhexamethylene guanidine is enhanced, moreover, the modified polyhexamethylene guanidine can also form stable hydrogen-bond interaction with phosphate groups in modified polyethylene, and the antibacterial property of the modified polyhexamethylene guanidine is improved. And the two-phase bonding capacity is enhanced, so that the overall mechanical property of the composite material is improved.

This invention relates to the field of antibacterial material application technology, specifically a method for preparing dual-targeted antibacterial and osteogenic nanomaterials for implant modification. The nanomaterials are prepared by mixing anhydrous citric acid as a carbon source and polyhexamethylene guanidine hydrochloride and diallyl dimethyl ammonium chloride as heteroatom dopant sources to provide guanidine and ammonium groups, respectively. This invention exerts stable antibacterial efficacy against six common infectious bacteria by inhibiting biofilms, disrupting bacterial membranes, and inhibiting bacterial energy metabolism, avoiding antibacterial failure and bacterial resistance risks caused by biofilms and the closed bone marrow cavity microenvironment. Simultaneously, it promotes stable osteogenic properties by promoting glutathione production, clearing ROS, and promoting mitochondrial metabolism to improve bone regeneration in the infected microenvironment, achieving a dual antibacterial and osteogenic effect, effectively solving the defects of lacking osteogenic function and insufficient biosafety.

The application discloses a preparation method of an antibacterial and cell adhesion promoting orthopedic implant, and steps are as follows: 1) configuring a water solution of polyphenol compounds, adding polyhexamethylene guanidine hydrochloride and arginine-glycine-aspartic acid into the water solution, wherein the mass concentration ratio of the polyhexamethylene guanidine hydrochloride and the arginine-glycine-aspartic acid is 50:1-200:1; 2) soaking the implant base material in the solution at room temperature for 12-24 hours; and 3) after cleaning, the antibacterial and cell adhesion promoting orthopedic implant is obtained. The application realizes competitive growth of bacteria and cells, i.e. cell> bacterial growth. The antibacterial and cell adhesion promoting orthopedic implant realizes a win-win of antibacterial and adhesion promoting and bone forming, and can reduce the problem of implant loosening caused by infection in orthopedic surgery to a certain extent.

The application belongs to the technical field of fabrics, and particularly relates to an antibacterial moisture-absorbing and air-permeable pure cotton fabric, a preparation method and application in non-allergic underwear. The application uses cotton fibers to prepare the fabric, and the fabric has good moisture absorption and air permeability. Dimethylaminoethyl methacrylate reacts with chlorinated modified nano zinc oxide under the action of a catalyst potassium iodide to generate alkenyl modified nano zinc oxide. The alkenyl modified nano zinc oxide reacts with methacryloyl ethyl sulfobetaine under the action of a Ce(IV) salt initiator under acidic conditions, and graft copolymerization occurs with cotton fibers to obtain grafted cotton fibers. The cotton fibers are introduced with an antibacterial component through graft modification treatment, and the antibacterial performance can be effectively improved. The grafted cotton fibers are first spun into pure cotton yarn, and then spun into pure cotton fabric. The pure cotton fabric is subjected to antibacterial finishing of polyhexamethylene guanidine hydrochloride, and the antibacterial performance of the pure cotton fabric is further improved.

The invention relates to the technical field of fabrics, and discloses an antibacterial and deodorant nylon fabric and a preparation method thereof. The preparation method of the antibacterial and deodorant nylon fabric comprises the following steps: reacting mercaptoethylamine with eugenol to obtain an intermediate product; the preparation method comprises the following steps: modifying nano titanium dioxide by using a silane coupling agent KH560 and an intermediate product in sequence, mixing with nylon 56, an ethylene-methyl acrylate-glycidyl methacrylate terpolymer and polyhexamethylene guanidine, and carrying out blending extrusion, grain-sized dicing and melt spinning to obtain the modified bio-based nylon 56 filament. The modified bio-based nylon 56 filaments are woven into the bio-based nylon 56 fabric after being soaked in a polyacrylic acid / aqueous solution; and treating the bio-based nylon 56 fabric with the antibacterial and deodorant finishing liquid to obtain the antibacterial and deodorant nylon fabric. The antibacterial and deodorant nylon fabric disclosed by the invention has excellent antibacterial and deodorant properties and washability.

The invention provides a preparation method of a chicken quadruple inactivated vaccine composition containing riemerella anatipestifer, and relates to the field of duck plague vaccine.The preparation method comprises the steps that a chitosan-based endotoxin adsorption-inactivating agent is prepared, specifically, chitosan is subjected to carboxymethylation after being swelled in an alkali solution, then reacts with polyhexamethylene guanidine under the action of an activating agent, and purification and concentration are conducted to obtain the chitosan-based endotoxin adsorption-inactivating agent; preparing a saponin-cholesterol composite immunologic adjuvant nanocapsule: after cholesterol and cationic lipid form a film, carrying out hydration ultrasonic treatment to form cationic lipidosome, adding saponin into the cationic lipidosome, and carrying out high-pressure homogenization and sterile filtration to obtain the nanocapsule; treating and mixing antigens, namely incubating, inactivating and purifying riemerella anatipestifer liquid by the adsorption-inactivating agent, centrifuging, taking supernatant, and mixing the supernatant with a Newcastle disease virus antigen, an H9 subtype avian influenza virus antigen and a bursal disease virus VP2 protein antigen; emulsifying and forming: adding the saponin-cholesterol nanocapsule into the antigen mixed solution, uniformly mixing to obtain a water phase, curing at low temperature, and sub-packaging to obtain the product. The four antigens are effectively integrated, and the immunogenicity and the safety are achieved.