72 results about "Polyhexamethyleneguanidine hydrochloride" patented technology

The invention discloses a chitosan hydrogel for an antibacterial dressing and a preparation method thereof. The chitosan hydrogel for the antibacterial dressing comprises, by weight, 2 to 6 parts of chitosan, 5 to 20 parts of a water-soluble monomer, 1 to 5 parts of an antibacterial agent polyhexamethyleneguanidine hydrochloride, 0.015 to 0.1 part of a cross-linking agent, 1 to 5 parts of a condensing agent, 1 to 5 parts of an activator, 0.1 to 0.5 part of an initiator and 109 to 145 parts of dimethyl sulfoxide. The preparation method comprises the following steps: introducing a carboxyl group on chitosan in the manner of free radical polymerization; subjecting the carboxyl group introduced on chitosan and the antibacterial agent polyhexamethyleneguanidine hydrochloride to an amidation reaction by using the condensing agent and the activator; and uniformly mixing chitosan for the antibacterial dressing with the cross-linking agent and pouring an obtained mixture into a die for a reaction so as to obtain the hydrogel with good drug resistance, good antibacterial property, a lasting antibacterial effect, high water absorption and good mechanical properties.

The invention relates to the bactericide technical field, in particular to a method for producing and making polyhexamethylene guanidine hydrochloride. The method comprises the following steps that: a. the raw material is matched; the mass ratio of guanidine hydrochloride to 1,6-diaminohexane is 1:1; b. the matched raw materials are put into a reaction kettle and are heated to the complete dissolution as well as are mixed sufficiently, the temperature is raised to between 120 and 200 DEG C, a catalyst is added in the temperature-rise period; 2. the reaction lasts 2 to 3 hours to the extent that no NH3 discharges from the reaction kettle, the reaction is over, and the product of polyhexamethylene guanidine hydrochloride is obtained. The method solves the problems of the prior polyhexamethylene guanidine hydrochloride that the polymerization degree is low, the sterilization period is short, and the pH range is not wide.

The present invention discloses a health sterilization wet tissue, which comprises a nonwoven fabric adopted as a carrier of a health sterilization emulsion, wherein a weight ratio of the health sterilization emulsion to the carrier is 0.5-5:1, and the health sterilization emulsion comprises, by weight, 80-99% of deionized water, 0.1-3% of polyhexamethyleneguanidine hydrochloride, 0.1-2% of 1,2-propylene glycol, 0.01-0.5% of vitamin E, 0.05-1% of a flavor, 0.003-0.1% of EDTA-4Na, 0.01-6% of aloe gel lyophilized powder (200:1), and the balance of citric acid or sodium citrate. The health sterilization wet tissue has the following characteristics that: bactericdal power can achieve 90%, bacterial can be effectively killed, and effects of skin moisturizing and protection, tender, smooth and soft skin protection, pleasant aroma, and no side effect are provided. In addition, the health sterilization emulsion production method has characteristics of simple operation and high production efficiency.

The invention discloses a preparation method of polyhexamethyleneguanidine hydrochloride. The method comprises the following steps: (1) polycondensation reaction: adding raw materials guanidine hydrochloride and 1,6-hexamethylenediamine into a reactor, stirring and heating to react in two stages, wherein the reaction is carried out for 2-10 hours after the material temperature is raised to 130-150 DEG C in the first stage, and the reaction is carried out for 1-5 hours after the material temperature is raised to 185-195 DEG C in the second stage; (2) saponification reaction: lowering the material temperature to 140-160 DEG C, adding a sodium hydroxide solution to regulate the pH value to 12 or above, and after finishing adding the sodium hydroxide solution, keeping the temperature at 90-120 DEG C for 1 hour or above; (3) skimming and washing: separating out the lower water layer of the reaction solution, and washing the upper layer with water to obtain water-insoluble polyhexamethyleneguanidine; (4) salification: dissolving the polyhexamethyleneguanidine in a hydrochloric acid solution, and regulating the pH value of the solution to obtain the polyhexamethyleneguanidine hydrochloride water solution; and (5) drying: drying the water solution to obtain the high-purity polyhexamethyleneguanidine hydrochloride product. The method has the advantages of mild reaction conditions and simple preparation process. The purity of the obtained product is 96% or above, the yield can reach 90% or above, and the product is suitable for large-scale production and application.

The invention discloses antibacterial POM plastic comprising the components of, by weight, 100 parts of POM and 0.3-0.5 parts of a composite antibacterial agent. The composite antibacterial agent is composed of the components of, by weight: 2-6 parts of cedar oil, 4-8 parts of chitosan, 10-20 parts of nano-grade titanium dioxide, 15-25 parts of nano-grade silver oxide, 30-50 parts of polyhexamethylene guanidine phosphate, and 2-4 parts of trichlorocarbanilide. The antibacterial POM plastic provided by the invention has high bacterium inhibition, bacterium killing, and anti-mildew effects. The plastic can be used for producing parts such as anti-friction wear-resistant parts, transmission parts, and chemical and instrument parts.

The invention discloses an antibacterial modified graphene oxide and a preparation method thereof. The preparation method comprises following steps: weighing a certain amount of graphene oxide, addinga certain amount of water, carrying out dispersing under the assistance of ultrasonic waves for one hour to obtain evenly dispersed graphene oxide water dispersion; weighing a certain amount of polyhexamethylene guanidine hydrochloride, gentamycin, penicillin, kanamycin, and etimicin, adding the components mentioned above into the graphene oxide water dispersion in sequence, stirring the grapheneoxide water dispersion for 1 hour under the assistance of ultrasonic waves, adjusting the pH, carrying out reactions for 48 hours at a temperature of 60 DEG C under mechanical stirring, cooling the reaction product to the room temperature, performing centrifugal washing for three times, placing obtained centrifugal product in a vacuum baking oven with a temperature of 40 DEG C, and drying the centrifugal product in vacuum for 24 hours to obtain the antibacterial modified graphene oxide. The prepared antibacterial modified graphene oxide has the advantages that the equipment requirements are low, the technology is simple, after modification, the antibacterial performance of graphene oxide is largely improved, and the modified graphene oxide has a very good antibacterial performance and biocompatibility and can be used in the fields of biomedicine and antibiosis.

The invention discloses a fragrant agent used for disposable sanitary products. The fragrant agent comprises the following raw materials in parts by weight: 0.5-2 parts of essence, 5-2.5 parts of propylene glycol, 5-10 parts of cocoglycerides, 5-15 parts of hydrogenated castor oil polyethenoxy ether CO40, 8-10 parts of polyhexamethylene guanidine hydrochloride and 38-76.5 parts of purified water, and does not contain ethanol to reduce the volatilization of the essence; the polyhexamethylene guanidine hydrochloride is adopted as an antiseptic agent, is sprayed on surface layers of sanitary towels and protective pads and has an obvious bacteriostasis function; the cocoglycerides and the essence are used as oil phases, the hydrogenated castor oil polyethenoxy ether is used as an emulsifier, the propylene glycol is used as an auxiliary emulsifier, an oil-in-water microemulsion liquid is used for reducing the volatilization of the essence, and the time of retaining fragrance is increased.

The invention discloses a special disinfectant for examination apparatuses in a clinical laboratory, and a preparation method thereof. The special disinfectant for examination apparatuses in a clinical laboratory comprises, by weight, Greater Celandine Herb, Chinese Incarvilla Herb, Spica Prunellae, root of Cudrania cochinchinensis Kudo et Masam, Wikstroemia indica, Root of Oriental Buckthorn, whiteflower violet herb with root, Cottonrose Hibiscus, dried orange peel, pomegranate rind, dark plum, Immature Bitter Orange, sodium dodecyl sulfate, Cornus officinalis, loquat leaf, sodium sulfosuccinate, pummelo peel, Ligustri Lucidi Fructus, dahurian angelica root, Vietnamese Sophora Root, corn silk, Ligusticum wallichii, fungus-infected rice spike, alkyl alcohol amide, Christmas flower and polyhexamethyleneguanidine hydrochloride. The special disinfectant has the advantages of good stability, high solubility in water, easy flushing and no residual after disinfection, very small corrosion to examination apparatuses, simple preparation process, suitableness for large-scale production, no irritation to human body skins, safety, and no toxic or side effects, can be widely applied to clinical laboratory personnel skin and apparatus disinfection, improves the working efficiency of clinical laboratory personnel, and guarantees the accuracy of an examination result.

The invention provides an environment-friendly multifunctional scale inhibitor. The environment-friendly multifunctional scale inhibitor is prepared from, by weight, 45-70% of phosphorus-free chelating agent, 3-10% of natural polymer, 5-15% of scaling inhibitor, 0.3-1% of dodecyl dimethyl glycine betaine, 0.1-0.5% of polyhexamethylene guanidine hydrochloride and the balance water, wherein the scaling inhibitor is at least one of a sulfonic acid copolymer and a maleic anhydride copolymer. In addition, the invention also provides a preparation method and application of the scale inhibitor. A trace amount of dodecyl dimethyl glycine betaine and a trace amount of polyhexamethylene guanidine hydrochloride are added into the scale inhibitor and play the cooperative synergistic effect on scale inhibition, the finally prepared scale inhibitor has the remarkable scale inhibiting effect on three types of scale calcium carbonate, calcium phosphate and barium sulfate and is free of phosphorus andpollution to the environment and is environmentally friendly, and the problems of oil field water scaling and blockage can be effectively solved.

The invention discloses an antibacterial and hydrophilic softening finishing agent for cotton fabric and a preparation method of the softening finishing agent. Isophorone diisocyanate and tetrahydrofuran-ethylene oxide copolymeric glycol are subjected to a reaction, and a polyurethane prepolymer is prepared; the polyurethane prepolymer reacts with hydroxyl polydimethylsiloxane, polyhexamethyleneguanidine hydrochloride dissolved in dimethylsulfoxide is added, the mixture continuously reacts, and the antibacterial and hydrophilic softening finishing agent for cotton fabric is prepared. The process is simple, the reaction process is convenient to control, the molecule structure of the obtained antibacterial and hydrophilic softening finishing agent contains more polyether segments and organosilicon segments, the antibacterial and hydrophilic softening finishing agent has better hydrophilic and softening effects, besides, polyurethane segments of the tetrahydrofuran-ethylene oxide copolymeric glycol structure in the molecule have good low-temperature elasticity and low-temperature flexibility and can endow the finished fabric with better resilience, polyhexamethyleneguanidine hydrochloride has a batter antibacterial effect and can endow the finished fabric with better antibacterial performance, and the softening finishing agent has good application prospects.

The invention discloses a preparation method of an antifouling and antibacterial polypropylene non-woven fabric finished with silk fibroin for bandages. The method includes the steps that a grafting solution is dropwise added to the surface of a polypropylene non-woven fabric obtained after irradiation-plasma pretreatment; the polypropylene non-woven fabric is covered with a quartz plate, placed in an ultraviolet lamp box for irradiation, taken out, ultrasonically washed with ultrapure water and ethanol alternately, put into a polyhexamethylene guanide hydrochloride aqueous solution, taken outafter a reflux reaction, ultrasonically washed with ultrapure water and ethanol alternately, and then subjected to vacuum drying; the obtained surface-functionalized antifouling and antibacterial polypropylene non-woven fabric is dipped in a silk fibroin solution and subjected to two-dipping and two-rolling, and the dipped and rolled cloth specimen is dried, treated with an ethanol solution, dried to a constant weight and then placed in a dryer for balance; the obtained silk fibroin functionally-modified polypropylene non-woven fabric is dipped in a graphene finishing liquid, and the non-woven fabric is treated with a small padder, dried and then baked.

The present invention relates to a polyhexamethyleneguanidine hydrochloride iodine medicine bath liquid and a preparation method thereof. The polyhexamethyleneguanidine hydrochloride iodine medicine bath liquid comprises the following components, by mass, 0.2-2 parts of iodine, 0.5-5 parts of potassium iodide, 0.1-1 part of potassium iodate, 0.1-1 part of sodium tripolyphosphate, 5-50 parts of polyhexamethyleneguanidine hydrochloride, 1-20 parts of a detergent, 0.5-5 parts of a skin care agent, 0.05-1 part of citric acid, and 15-92.55 parts of water. The preparation method comprises: respectively adding the polyhexamethyleneguanidine hydrochloride, the detergent and the skin care agent to the water, and stirring at a temperature of 45-70 DEG C until mixing is uniform; then adding the iodine, the potassium iodide, and the potassium iodate, and stirring at a temperature of 45-70 DEG C to completely dissolve; and adding the sodium tripolyphosphate and the citric acid, and stirring at a temperature of 45-70 DEG C until all components are completely dissolved to obtain the product. The medicine bath liquid of the present invention has characteristics of high effective iodine content, high sterilization effect and good stability, and is suitable for pastures. The preparation method of the present invention has a characteristic of simple operation, and can be applicable for large-scale production.

The invention relates to the technical field related to elimination of thalli, and particularly provides a preparation for strongly eliminating vibrios and a preparing method of the preparation. On one hand, provided is the preparation for strongly removing vibrios, wherein the preparation comprises the components in percentage by weight: 65-85% of a first guanidine derivative, 2-12% of a second guanidine derivative and the balance being ethanol, wherein the first guanidine derivative is polyhexamethylene guanidine salt and / or polyhexamethylene biguanide salt; and the relative molecular weightof the second guanidine derivative is 500-1500. The vibrios can be effectively removed by utilizing polyhexamethylene guanidine hydrochloride and chlorhexidine hydrochloride under the specific content. The preparation provided by the invention has a strong removal effect on pathogenic vibrios, such as vibrio parahaemolyticus, vibrio anguillarum, vibrio alginolyticus, vibrio cholerae, vibrio fluorescens and the like, has a good cracking effect on aeromonas hydrophila, aeromonas punctata, escherichia coli, salmonella and other gram-negative bacteria, and has a quite high removal rate after being used for 48 hours.

The invention provides an inkjet printing method by using coating-type ink with organic-inorganic coated pigment color paste. The method comprises the following steps that gelatin is used as a wall material for preparing microcapsule pigment, and carboxylation treatment is conducted; the pigment is added to an acrylamide monomer emulsion, and ammonium persulfate is added for a reaction to prepareacrylamide-coated microcapsule pigment; a nano titanium dioxide particle layer is deposited on the surface of a polyacrylamide layer, the surface of the polyacrylamide layer is modified with aminoethyl imine propyl polydimethylsiloxane, modified microcapsule pigment is prepared, and the modified microcapsule pigment, a surfactant and deionized water are mixed for preparing the microcapsule pigmentcolor paste; the microcapsule pigment color paste is mixed with ethylene glycol, sodium polyacrylate, polyhexamethylene guanide hydrochloride and deionized water, after filtering and desalting are conducted, the coating ink is prepared, and a fabric is subjected to inkjet printing treatment. The prepared coating ink is good in dispersibility and affinity with fabric fibers, diffusion in the printing process is effectively prevented, and the bright degree of fabric printing patterns is improved.

The invention relates to an application of a polyethyleneimine grafted guanidine polymer, which comprises the following steps: forming a guanidine polymer by using polyhexamethylene guanidine hydrochloride and branched polyethyleneimine or ethylenediamine terminated polyethyleneimine, and grafting the polyethyleneimine grafted guanidine polymer by using the guanidine polymer as a grafting agent, other sterilization and disinfection compounds, disinfectants or water treatment filter membranes are grafted and modified, so that the bacteriostasis and disinfection effects of other sterilization and disinfection compounds, disinfectants or filter membranes are enhanced or endowed, and the sterilization and disinfection effect duration is prolonged. The application range of the guanidine disinfectant is widened, and the sterilization and disinfection efficiency and action time of the guanidine disinfectant are greatly improved from the aspects of effective binding property of guanidyl on a target compound / product, adsorbability of the guanidyl on the surface of a microbial cell membrane, distribution density of the guanidyl, the guanidyl overcoming steric hindrance and being exposed outside molecules and the like.

The invention belongs to the technical field of washing articles, and discloses hand-washing-free disinfection gelatin and a preparation method and application thereof. The hand-washing-free disinfection gelatin comprises the preparation raw materials of 0.5% of polyhexamethyleneguanidine hydrochloride, 50-55% of ethanol, 10% of n-propanol, 2-4% of glycerine, 0.5% of carbomer 940, 0.5% of triethanolamine, 0.05% of essence and the balance purified deionized water. The preparation method comprises the steps of enabling the carbomer 940, the polyhexamethyleneguanidine hydrochloride, the essence,the n-propanol, the triethanolamine, the glycerine and the essence to dissolve in an ethanol solution, and performing stirring to obtain a homogeneous solution; adding the purified ionized water to full amount, maintaining constant volume, and performing aging; examining the obtained intermediate products; and if the examining result is qualified, performing encapsulation with disinfecting liquidplastic bottles and heads, and performing external packing; and examining finished products, enabling qualified products to enter a finished product warehouse, and performing storage. The hand-washing-free disinfection gelatin has the efficacy of moistening skin and holding water, is fast to dry and free from thickness, free from irritating to hand skin, and can prevent washing with clean water, and the disinfecting and sterilizing effect holding time is long.

The invention discloses a preparation method of nano cellulose antibacterial hydrogel. The method comprises the following steps: (1) preparing TEMPO oxidized nanocellulose colloid; (2) preparing a polyhexamethylene guanidine hydrochloride aqueous solution; and (3) placing the TEMPO oxidized nano-cellulose colloid into a polytetrafluoroethylene mold, dropwise adding a polyhexamethylene guanidine hydrochloride aqueous solution, performing standing treatment for 24-48 hours, and performing electrostatic adsorption coupling on the TEMPO oxidized nano-cellulose colloid and the polyhexamethylene guanidine hydrochloride aqueous solution to form the nano-cellulose antibacterial hydrogel. The method is simple in process and environmentally friendly in raw material, and the prepared nano-cellulose hydrogel has high strength and good antibacterial performance and is widely applied to the fields of drug loading, controllable release, chemical sensors and the like.

The invention discloses a chitosan hydrogel for an antibacterial dressing and a preparation method thereof. The chitosan hydrogel for the antibacterial dressing comprises, by weight, 2 to 6 parts of chitosan, 5 to 20 parts of a water-soluble monomer, 1 to 5 parts of an antibacterial agent polyhexamethyleneguanidine hydrochloride, 0.015 to 0.1 part of a cross-linking agent, 1 to 5 parts of a condensing agent, 1 to 5 parts of an activator, 0.1 to 0.5 part of an initiator and 109 to 145 parts of dimethyl sulfoxide. The preparation method comprises the following steps: introducing a carboxyl group on chitosan in the manner of free radical polymerization; subjecting the carboxyl group introduced on chitosan and the antibacterial agent polyhexamethyleneguanidine hydrochloride to an amidation reaction by using the condensing agent and the activator; and uniformly mixing chitosan for the antibacterial dressing with the cross-linking agent and pouring an obtained mixture into a die for a reaction so as to obtain the hydrogel with good drug resistance, good antibacterial property, a lasting antibacterial effect, high water absorption and good mechanical properties.

The invention provides a sterilizing and disinfecting agent being composed of: bicyanamide, ammonium chloride, 1,6-diamidohexane, a catalyst and water. The sterilizing and disinfecting agent is prepared through following processes: (1) performing a melt reaction to the bicyanamide and the ammonium chloride at 170-230 DEG C to obtain guanidine hydrochloride; (2) feeding the guanidine hydrochloride and the 1,6-diamidohexane into a reaction kettle according to the ratio of 1:1 and heating the guanidine hydrochloride and the 1,6-diamidohexane until the reactants are completely dissolved and fully mixed; (3) increasing the temperature to 120-200 DEG C with addition of the catalyst and performing a reaction for 2-3 h until no ammonia gas is discharged from the reaction kettle; (4) when the temperature of the reactants is decreased to 80 DEG C, adding a proper amount of water to finish the reaction for obtain an aqueous solution of poly-hexamethylene biguanide hydrochloride. The sterilizing and disinfecting agent can be used in water treatment in the fields of agriculture, leather industry, breeding industry of poultry and livestock, oil extraction and the like.

The invention relates to a compositing and compounding process for a bactericide for oilfield wastewater reinjection treatment. The compositing and compounding process comprises steps as follows: (1), hexamethylenediamine is added to a reaction kettle, the temperature is raised in a stirring state, and iminourea hydrochloride is added; (2), the temperature is raised continuously, a thermostatic reaction is performed, and meanwhile, hydrochloric acid is added dropwise to serve as a catalyst; (3), the temperature is raised continuously, and a thermostatic reaction is performed; (4), after the reaction is finished, water and hydrochloric acid are added and uniformly stirred, and a product generated in the reaction is polyhexamethyleneguanidine chloride; (5), polyhexamethyleneguanidine chloride, tetrakis hydroxymethyl phosphonium sulfate, a biquaternary ammonium salt bactericide, nonylphenol polyoxyethylene ether-10, methylisothiazolinone and water are added to a preparation kettle and fully stirred; (6), a sodium hydroxide solution is added, and a pH (potential of hydrogen) value is adjusted to range from 7 to 9. The process has the beneficial effects that the character is stable; adding is simple; various agents are compounded, so that the problem of bacterial resistance is solved; the purpose of quickly killing bacteria in waste through the bactericide with lower concentration is achieved.

The invention provides a lysimachia christinae hance fiber antibacterial textile fabric and a preparation method thereof. The preparation method comprises the following steps that bamboo fibers, cotton fibers, polyester filament fibers and lysimachia christinae hance fibers are blended into yarns, sectional warping is carried out to prepare a warp beam, slashing is carried out by adopting a composite antibacterial sizing agent, airing is carried out, and a lysimachia christinae hance fiber fabric gray fabric is produced on a shuttle loom; fabric pre-finishing, printing and dyeing treatment and after-finishing are carried out; and the composite antibacterial slurry is prepared from 1-3 parts of ethylenediamine copper complex, 10-30 parts of organosilicon quaternary ammonium salt, 2-5 parts of polyhexamethylene guanidine hydrochloride, 75-80 parts of ethanol and 45-60 parts of water. Bamboo fibers, cotton fibers, polyester filament fibers and lysimachia christinae hance fibers are used as raw materials, slashing is carried out through the composite antibacterial sizing agent, and the textile with the antibacterial function and soft, fine, smooth and fine hand feeling is obtained.

The invention discloses a hollow mesoporous silica antibacterial agent grafted with a guanidine salt polymer and a preparation method thereof. The method includes the following steps that (1), epoxy modified hollow mesoporous silica microspheres are synthesized by a miniemulsion method, wherein an inorganic silicon source monomer, gamma-glycidyl ether oxypropyl trimethoxysilane, a hydrophobic solvent and a co-stabilizer serve as oil phases, an emulsifier and deionized water serve as water phases, and the oil phases and the water phases are mixed, homogenized and emulsified to obtain miniemulsion; a cross-linking agent is added for magnetic stirring at room temperature for 24 hours, and then epoxy modified hollow mesoporous silica microspheres are obtained; (2), guanidine salt polymer-polyhexamethylene guanide hydrochloride (PHMG) is prepared; (3), the epoxy modified hollow mesoporous silica is dispersed in water, a PHMG aqueous solution is added, and after magnetic stirring at room temperature for a certain time, the hollow mesoporous silica microspheres grafted with the guanidine salt polymer is obtained. The PHMG is grafted onto the surfaces of the hollow mesoporous silica microspheres to prepare the novel antibacterial agent, the antibacterial agent has excellent antibacterial performance, and involved raw materials are cheap, easy to obtain, and environmentally friendly.

The invention relates to the technical field of spinning, and particularly discloses an antibacterial polyester combined fiber elastic yarn and a preparation method thereof. The antibacterial polyester combined fiber elastic yarn comprises fully-drawn yarn and pre-oriented yarn, and the fully-drawn yarn and the pre-oriented yarn are co-twisted, elasticized and then soaked in an antibacterial agent for antibacterial finishing; the antibacterial agent is prepared from the following raw materials in parts by weight: 0.9 to 1.5 parts of lithium carbonate, 1.2 to 2 parts of chitin, 1.6 to 3 parts of polyhexamethylene guanidine hydrochloride, 0.05 to 0.1 part of anhydrous potassium carbonate and 1000 to 2000 parts of water, and the polyhexamethylene guanidine hydrochloride is modified by glycerol triglycidyl ether, so that the glycerol triglycidyl ether is grafted to the polyhexamethylene guanidine hydrochloride. The antibacterial polyester combined fiber elastic yarn is excellent in elastic performance, antibacterial performance and washing resistance.

The invention relates to a medical cationic polymer antimicrobial dressing and a preparation method. The antimicrobial dressing is a polymer including polyhexamethylene guanide hydrochloride, chitosanand polyvinyl alcohol, and the antibacterial dressing comprises the following components in parts by weight: 1-5 parts of chitosan, 0.05-0.4 part of polyhexamethylene guanide hydrochloride and 0.05-0.75 part of polyvinyl alcohol. The antimicrobial dressing has the beneficial effects that the long-chain guanidine polyhexamethylene guanide hydrochloride and the polymer chitosan are selected to synergistically exert the antimicrobial ability, and the dressing is processed by utilizing good mechanical properties of the long-chain guanidine polyhexamethylene guanide hydrochloride and the polymer chitosan; the antimicrobial dressing is not prone to fall off, is not prone to enter the human body, and a 3D porous spongy dressing can be prepared, so that the dressing has good water absorption andmoisture retention properties; and the antimicrobial dressing can have a local broad-spectrum antimicrobial property, is not prone to develop drug resistance, has low toxicity, has a good effect of promoting wound healing, provides a mechanical protection effect for a wound, absorbs exudates, keeps the wound moist and has high biocompatibility, and the drug is not prone to enter blood.

The invention discloses a long-acting antibacterial fabric coating and a preparation method thereof, and belongs to the field of green functional polymer materials. The preparation method comprises the following main operation steps: (1) preparing a gamma-glycidoxypropyltrimethoxysilane (KH560) solution, namely a treatment solution A; (2) preparing a polyhexamethylene guanidine hydrochloride (PHMG) solution, namely a treatment solution B; (3) soaking a treated fabric in the treatment solution A and the treatment solution B respectively to form an antibacterial coating on the surface of the treated fabric. KH560 is used as a bridge to fix PHMG on the surface of the fabric, and the reaction mechanism is as shown in figure 1; the treated fabric has excellent antibacterial performance, the antibacterial rate of gram-negative bacteria representing escherichia coli and gram-positive bacteria representing staphylococcus aureus reaches 99.0% or above, the antibacterial effect of the fabric isbasically unchanged after being eluted by 100%, the whole treatment process is simple to operate, the cost is low, and the method has important significance for improving the production and living environment of people and preventing spread of bacterial viruses.

The invention provides high-quality, antibacterial and anti-mildew inner wall latex paint and preparation and application methods thereof. The high-quality, antibacterial and anti-mildew inner wall latex paint comprises a styrene-acrylic emulsion, polyhexamethyleneguanidine hydrochloride, phenoxyethanol, 2-amino-2-methyl-1-propyl alcohol, propylene glycol, nonylphenol polyoxyethylene ether, hydroxyethyl cellulose, an antifoaming agent, titanium dioxide, kaolin, ground calcium carbonate, 2, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, a thickening agent and water. The high-quality, antibacterial and anti-mildew inner wall latex paint has the advantages that the latex paint is reasonable in component, good in stability and good in pigment wettability, and the antibacterial component polyhexamethyleneguanidine hydrochloride can be well and evenly dispersed in the paint, has good antibacterial and sterilizing effects and can automatically kill bacteria, germs and mildew attaching to an inner wall.

The invention relates to the field of plastic films, and particularly discloses a BOPP film and a preparation method thereof.The BOPP film comprises a surface layer, a core layer and a bottom layer, and the core layer is prepared from, by weight, 50-60 parts of polypropylene; 2-3 parts of nano titanium dioxide; 0.2-0.4 part of an antibacterial agent; 0.1-0.2 part of a slipping agent; 0.5-1 part ofan antistatic agent; and 5-6 parts of a pearling agent. Polyhexamethylene guanidine hydrochloride is adopted as the antibacterial agent. The polyhexamethylene guanidine hydrochloride is an organic antibacterial agent with a certain polymerization degree, does not contain a heterocyclic structure, is relatively high in safety, has a melting point far lower than the processing temperature of polypropylene, can be fully melted in the polypropylene during processing, does not easily influence the haze and light transmittance of the antibacterial BOPP film, and provides a good antibacterial property for the BOPP film.

The invention discloses a skin antipruritic disinfectant formula, relates to the technical field of skin antipruritic disinfection, glyceryl monostearate, stearic acid, liquid paraffin, medical vaseline, glycerin, polyhexamethyleneguanidine hydrochloride, Polyvinylpyrrolidone. By adopting the formula of the invention, the used disinfectant can exert the characteristics of traditional Chinese medicine, enhance the antibacterial and antibacterial curative effects, reduce the damage effect of skin cells, and have the characteristics of preventing mosquito bites.

The invention discloses a halogen-free flame-retardant polypropylene composite material and a preparation method thereof. The material comprises polypropylene and particularly consists of polyphosphate, polyhexamethylene guanidine salt and polypropylene according to the weight ratio of (1-2.5): (1-2.5): 20, wherein the polyphosphate is one of or a mixture of sodium polyphosphate and ammonium polyphosphate; the polyhexamethylene guanidine salt is one of or a mixture of more than two of polyhexamethylene guanidine phosphate, polyhexamethylene biguanidine hydrochloride and polyhexamethylene biguanide phosphate. The method adopts a melt-blending method and comprises the following steps: putting the polyphosphate, the polyhexamethylene guanidine salt and the polypropylene into a torque rheometer and mixing for 5-30 minutes at a temperature of 140-200 DEG C to prepare the halogen-free flame-retardant polypropylene composite material. The halogen-free flame-retardant polypropylene composite material is better in flame-retardant property, less in raw material required, simple and convenient to manufacture and low in cost and can be easily and widely applied to the fields of mechanical parts, corrosion-resistant parts, insulating parts, food utensils and the like.

The invention discloses an antibacterial agent and a wood-plastic composite material, wherein the antibacterial agent adopts a three-layer structure, and the particle diameter D50 of the antibacterialagent is less than 5 [mu]m, and the particle diameter D90 of the antibacterial agent is less than 12 [mu]m. The particle size of the antibacterial agent is controlled, the specific surface area of the antibacterial agent is increased, and the antibacterial effect is improved. The organosilicon quaternary ammonium salt on the outermost layer is adsorbed on the surfaces of bacteria to change the permeability of cell walls of the bacteria, so that microorganisms stop breathing and are killed, and the effects of sterilization and bacteriostasis are achieved, namely, contact death; if contact sterilization does not work, polyhexamethylene guanidine hydrochloride is adopted to enter cell membranes to inhibit synthesis of liposomes in the membranes to cause thallus apoptosis, so that an optimalsterilization effect is achieved; furthermore, the DNA molecules in bacterial cells are destroyed by using thiazolinone bactericides to inactivate bacteria. Through contact sterilization, entering a cell membrane to realize sterilization and deeper damage of DNA molecules in bacterial cells in sequence, the triple continuous cooperation has a better antibacterial effect.