The invention relates to a preparation method of an antibiotic medical dressing, and concretely relates to a preparation method of a nanosilver-carried calcium alginate antibiotic medical dressing. The problems of bad antibiotic performance, bad wettability, weak permeability and weak mechanical properties of present chitosan base medical dressings are solved in the invention. The preparation method comprises the following steps: carrying out chemical reduction of a silver nitrate solution by using sodium alginate as a stabilizing agent and a dispersant and sodium borohydride as a reducing agent to prepare a nanosilver sol, adding sodium alginate into the nanosilver sol, dumping the sodium alginate solution mixed with nanosilver particles into a culture dish to form a film, and crosslinking the sodium alginate film carried with nanosilver ions by using calcium chloride to obtain the calcium alginate dressing carried with the nanosilver ions. The antibiotic medical dressing has the advantages of rapid and efficient control of severe hemorrhage, antibiotic performance, good moisture absorption performance, good water steam transmittance, good biocompatibility, biodegradability, wound healing promotion capability, low price, simple operation, and suitableness for the scale production.