2046 results about "Benzothiazole" patented technology

The present invention relates to a binder composition for a fuel cell including a proton conductor and one or more binders selected from the group consisting of poly[2,2′-(m-phenylene)-5,5′-bibenzimidazole] (PBI), poly[2,5-benzimidazole] (ABPBI), polybenzoxazole (PBO), and polybenzothiazole (PBT).

The present invention discloses new quinolone derivatives with 3-position substituted by imidazol radical, benzoxazole and benzothiazole and possessing antitumor activity. The preparation process ofthe compounds is also disclosed.

The invention relates to a cable jacket rubber and a preparation method, wherein the cable jacket rubber has high elastic resilience, softness and abrasive resistance at a low temperature. The cable jacket rubber is characterized in that a base material of the rubber is formed by mixing 30 to 50 weight percent of natural gum and 50 to 70 weight percent of cis-butadiene rubber; a vulcanizing system in a rubber compounding agent is a low-sulfur high-accelerant vulcanizing system, the addition of sulfur is 0.3 to 0.6 weight percent of that of the base material of the rubbere, the addition of the accelerant tetramethylthiuram disulfide is between 1.0 and 1.3 weight percent, the addition of the accelerant N-cyclohexyl-2-benzothiazole sulfonamide is between 1.8 and 2.2 weight percent, and the addition of the accelerant diphenyl disulfide benzothiazole is between 0.6 and 0.9 weight percent. The cable jacket rubber has wide range of working temperature, and can be bent and distorted randomly without cracking at a long-term usage temperature of between 50 DEG C below zero and 70 DEG C, the impact elasticity is high and can reach 42 percent, the specific elongation is more than 350 percent, and the Akron abrasion loss is less than 2 percent, thus the cable jacket rubber is particularly suitable for wind-power generated electricity tower tube cables.

The invention discloses a visible and reversible fluorescent probe which comprises a cyanine fluorescent group and a benzothiazole group, and the general formula of the probe is shown in the description. The preparation method of the reversible fluorescent probe comprises the following steps: (1) dropwise adding phosphorus oxychloride into salicylaldehyde and paraformaldehyde for reaction, so as to obtain a product 1; (2) enabling the product 1 and hexamethylene-tetramine to react, so as to obtain a product 2; (3) enabling the product 2 and 2-aminobenzenethiol to react at the room temperature, so as to obtain a product 3; (4) enabling the product 3 and a compound 4 to react, so as to obtain the visible and reversible fluorescent probe. According to the ratiometric fluorescent probe provided by the invention, obvious color variation can be found out under natural light or an ultra-violet lamp, and the qualitative detection of sulfur dioxide gas can be implemented under natural light or a hand-held ultra-violet lamp, so that the operation is simple, high convenience and quickness are achieved, and the effect is remarkable; the fluorescent probe can effectively prevent interference from other impurities in samples, and is excellent in selectivity; in addition, the cumbersome pre-processing process of samples is avoided, so that the detection efficiency is high.

Removing metals from metal containing acidic solutions, such as contaminated waters and industrial wastewaters, is described. An amphipathic, heterocyclic, metal-coordinating compound (an extraordinaiy ligand) and a sorbent are added to a solution, such that the addition, at a specific acidic pH of the solution, causes at least some of the metal-coordinating compound to bind with some of the metal cations and at least some of the metal-coordinating compound sorbs to the sorbent, along with any metal cations bound therewith. The compound and the sorbent may be added to the solution, either together or independently, so that the compound may bind the metal. The metal binding compound may be a benzotriazole, a benzothiazole, or another compound to bind a metal. The sorbent is selected to interact with the metal-coordinating compound in sequestering the metal from solution as part of a complexation. Thereafter, the ligand-metal complex may be removed from the solution.

The invention relates to an optimized preparation method of a polyimide film. The optimized preparation method comprises the following steps: dissolving diamine monomers and dianhydride monomers which have benzimidazole and benzothiazole structures into a non-protonic solvent, so as to obtain yellow homogeneous-phase sticky polyamide acid (PAA) low-temperature glue liquid; and coating a film with the PAA low-temperature glue liquid, removing the solvent according to an optimized heating process, and carrying out amination, so as to obtain the polyimide film. The glass-transition temperature of the polyimide film is 309-482 DEG C, the 1% thermal decomposition temperature of the polyimide film is 448-520 DEG C, and the thermal expansion coefficient of the polyimide film at 50-250 DEG C is 4.213ppm/K-(-)2.054ppm/K. The polyimide film having relatively high heat stability and dimensional stability can meet bearing conditions of polyimide as a flexible substrate and is an ideal OLED substrate material.

The invention relates to a method for simulating peroxidase by manganese dioxide nanosheet for detection of reductive biological molecules. The peroxidase simulated by manganese dioxide nanosheet can perform catalytic oxidation on substrates of 3,3',5,5'-tetramethyl benzidine TMB, 2,2-azino-di(3-ethyl-benzothiazoles-6-sulfonic acid) diammonium salt ABTS and o-phenylenediamine OPD, and changes the color from colorless to blue, green and orange respectively, at the same time, the manganese dioxide nanosheet can sensitively and selectively perform an oxidation reduction reaction with reductive biological molecules such as glutathione and ascorbic acid, oxidation product concentration of the substrates such as TMB, ABTS and OPD is changed, and then, the reductive biological molecules such as glutathione and ascorbic acid are subjected to quantitative determination through a colorimetric analysis method. The method has the characteristics of simple operation, high sensitivity, good reappearance and high selectivity; a detection linear scope of glutathione is 1-15 [mu]M, the detection limit is 0.3 [mu]M; the detection linear scope of ascorbic acid is 3-100 [mu]M, the detection limit is 0.8 [mu]M; and the method can be used for detecting various phenolic compounds.

The process for the preparation of pramipexole base and/or its pharmaceutically acceptable salts, especially the hydrochloride salt, in the alkylation reaction of (S)-(−)2,6-diamino-4,5,6,7-tetrahydrobenzothiazole with an alkylating agent, wherein the reaction is carried out in the absence of a base, and in a solvent from which the resulting N-monoalkylated product selectively precipitates out as a salt. After isolation from the reaction mixture, the N-monoalkylated product is converted a) into the free pramipexole base upon treatment with an inorganic base and is then converted into another pharmaceutically acceptable pramipexole salt; or b) directly into another pharmaceutically acceptable pramipexole salt or the hydrate thereof.

An activator composition for the accelerated hardening of cyanoacrylate adhesives, wherein the activator comprises a member selected from the group consisting of: aromatic heterocyclic compounds having at least one N hetero atom in the ring(s) such as pyridines, quinolines and pyrimidines and substituted on the ring(s) with at least one electron-withdrawing group which decreases the base strength of the substituted compound compared to the corresponding unsubstituted compound, mixtures of any of the foregoing with each other, and/or with N,N-dimethyl-p-toluidine, and mixtures of any of the foregoing and/or N,N-dimethyl-p-toluidine with an organic compound containing the structural element, —N═C—S—S—, such as dibenzothiazyl disulfide. 6,6′dithiodinicotinic acid, 2,2′-dipyridyl disulfide, and bis(4-t-butyl-1-isopropyl-2-imidazolyl)disulfide. An activator composition may comprise a solution of one or more activators in a solvent mixture which comprises a volatile hydrocarbon and a cyclic ketone.

The invention relates to a preparation method of a thiofide (dibenzothiazyl disulfide), wherein, 2-mercaptobenzothiazole sodium salt is taken as a raw material, mixture of hydrogen peroxide and sulfuric acid is taken as an oxidizing agent, and the mol ratio of the hydrogen peroxide to the sulfuric acid is 0.5-2.5:1, and the method comprises the following steps (1) preparation process of the oxidizing agent: evenly mixing the hydrogen peroxide and the sulfuric acid in a container according to the mol ratio; and (2) oxidization process of the product: dropwise adding the mixture of the hydrogen peroxide and the sulfuric acid to a reaction kettle with the 2-mercaptobenzothiazole sodium salt at the temperature of 55 DEG C-65 DEG C while stirring for oxidization reaction for 60-80 minutes, keeping warm for about 0.5 hour after the oxidizing agent is added dropwise; then measuring pH value of the reaction solution, performing solid-liquid separation at the temperature of 30 DEG C when the pH value is stabilized within a range of 6.5-7.5, drying, crushing, screening and packaging the obtained solid to obtain the product. The method can help effectively enhance quality of the product, save energy and lower consumption and reduce 'three wastes' pollution.

The invention relates to a benzothiazole derivatives metal coordination polymer based on a bridged bis-salicylaldehyde structure, characterized by having the following structure which is shown in the specification, wherein linker is CH2 or C(CH3)2, R is H+, halogen base, phenyl or biphenyl, and M is Zn2+, Be2+ or Ca2+. The benzothiazole derivatives metal coordination polymer has favorable thermal stability, good fluorescent emission performance and simple preparation method. The coordination polymer of the type can be applied to the organic electroluminescent material aspect.

A medicament having inhibitory activity against NF-κB activation which comprises as an active ingredient a substance selected from the group consisting of a compound represented by the following general formula (I) and a pharmacologically acceptable salt thereof, and a hydrate thereof and a solvate thereof:

wherein A represents hydrogen atom or acetyl group, E represents a 2,5-di-substituted or a 3,5-di-substituted phenyl group, or a monocyclic or a fused polycyclic heteroaryl group which may be substituted, provided that the compound wherein said heteroaryl group is ① a fused polycyclic heteroaryl group wherein the ring which binds directly to —CONH— group in the formula (I) is a benzene ring, ② unsubstituted thiazol-2-yl group, or ③ unsubstituted benzothiazol-2-yl group is excluded, ring Z represents an arene which may have one or more substituents in addition to the group represented by formula —O-A wherein A has the same meaning as that defined above and the group represented by formula —CONH-E wherein E has the same meaning as that defined above, or a heteroarene which may have one or more substituents in addition to the group represented by formula —O-A wherein A has the same meaning as that defined above and the group represented by formula —CONH-E wherein E has the same meaning as that defined above.

The invention provides a triarylamine compound and an organic electroluminescent device thereof, and relates to the technical field of organic photoelectric materials. According to the invention, a substituted or unsubstituted 9-phenyl-fluorene group and a triarylamine group containing benzoxazole/benzothiazole/benzimidazole/benzotriazole undergoes a reaction to obtain the triarylamine compound by9-position (tertiary C) connection of fluorene. The triarylamine compound has a good hole transport capability, is high in glass transition temperature, good in thermal stability, good in film-forming property, high in refractive index and simple to synthesize, can be applied to an organic electroluminescent device to serve as a hole transport layer and/or a covering layer, can effectively solvethe problems of low luminous efficiency and short service life of the organic electroluminescent device, and has the advantages of high luminous efficiency and long service life.

The present invention relates to the compound of formula

which is 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, and to pharmaceutically acceptable acid addition salts thereof. It has been found that the compound is useful for the treatment or prevention of Alzheimer's disease, Parkinson's disease, Huntington's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, ADHD (attention deficit hyper-activity disorder), drug addiction to amphetamines, cocaine, opioids, ethanol, nicotine, or cannabinoids, or for the treatment of asthma, allergic responses, hypoxia, ischemia, seizure, substance abuse, or for use as muscle relaxants, antipsychotics, antiepileptics, anticonvulsants and cardioprotective agents.

This invention relates to use of stabilized unsymmetrical coupling agents for use in conjugated diene-based rubber compositions reinforced with silica-based reinforcement, namely use of stabilized 2-benzothiazyl-3-(triethoxysilylpropyl) disulfide and 3-(triethoxysilyl)propyl-N-maleamic acid. Said stabilized unsymmetrical coupling agent materials may be provided for mixing with said diene-based rubber(s), for example, as individual materials, as at least one of said materials being pre-reacted with aggregates of precipitated silica, said precipitated silica having hydroxyl groups (e.g. silanol groups) on its surface. The invention includes an article of manufacture, including a tire, having at least one component comprised of such rubber composition.

The invention relates to the technical field of rubber, in particular to a tyre tread rubber composition used in a hard mine area and a production method of the tread rubber composition in the hard mine area. The tyre tread rubber composition comprises the following materials by weight: 50-90 parts of styrene butadiene rubber, 10-50 parts of natural rubber, 45-55 parts of carbon black, 15-25 parts of white carbon black, 2-5 parts of zinc oxide, 1-3 parts of stearic acid, 2-4.5 parts of silane coupling agent, 2-5 parts of cutting resistant resin, 10-20 parts of aromatic oil, 1-3 parts of antioxidant N-(1,3-dimethylbutyl)-N'-phenyl p-phenylenediamine, 1-2 parts of antioxidant 2, 2, 4-trimethyl-1,2-dihydroquinoline polymer, 1-3.5 parts of microcrystalline wax, 1-2 parts of sulfur, 1.0-2.0 parts of vulcanization accelerant N-tertiary butyl-2-benzothiazole sulfonamide, 0.5-1.0 parts of vulcanization accelerant N,N-diphenylguanidine and 0.1-0.3 parts of scorch retarder. The tyre tread rubber composition used in a hard mine area and the production method provided by the invention can obviously improve puncture resistant property, the chipping resistant property, the safety and the service life of a tyre in the hard mine area.

The invention discloses a benzothiazole derivative containing a triphenylethylene or tetraphenylethylene structure and having aggregation-induced emission property and a preparation method and application thereof. The preparation method comprises the following steps: with 2-amino-6-methoxybenzothiazole as a start raw material, performing a ring-opening reaction under an alkaline condition to generate 2-amino-5-methoxythiophenol; performing a ring-closing reaction with an aromatic aldehyde compound containing a triphenylethylene or tetraphenylethylene structure to obtain a methoxy-containing benzothiazole derivative, or performing demethylation to obtain a hydroxyl-containing benzothiazole derivative, wherein the compound also can be modified through a group substitution reaction to generate a benzothiazole derivative containing other functional groups. The benzothiazole derivative disclosed by the invention has relatively low luminous intensity in a solution, emits strong fluorescence in an aggregation state or solid state, and belongs to good aggregation-induced emission materials; the synthesis is relatively simple, and the cost of the raw materials is low, so that large-scale commercial production is easy to realize; the benzothiazole derivative plays an important role in the fields of electroluminescent devices, fluorescent probes, fluorescent switches, organism imaging and the like.

The present invention discloses a synthesis method for a benzothiazole unit-based covalent organic framework material. The method comprises the following step of: in an organic solvent or an ionic liquid, performing a reaction on 2, 4, 6-trihydroxy benzenetricarboxaldehyde and 2, 6-diamino benzodithiazole to obtain the covalent organic framework material. The covalent organic framework material prepared by the method has a relatively large surface area and a regular channel structure, and is a good photocatalytic material; and the material can be used for cross-dehydrogenation coupling reaction for photocatalysis of N-aryl tetrahydroisoquinoline, and has good stability and an excellent catalytic effect.