Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

55 results about "Silver trifluoromethanesulfonate" patented technology

Silver trifluoromethanesulfonate, or silver triflate is the triflate (CF₃SO₃⁻) salt of Ag⁺. It is a white or colorless solid that is soluble in water and some organic solvents (most interestingly, benzene). It is a reagent in the synthesis of organic and inorganic triflates.

Method for preparing 2-amino-1,2-dihydro-isoquinoline compound

The invention belongs to the technical field of organic chemistry, in particular to a method for preparing a 2-amino-1,2-dihydro-isoquinoline compound. The structure of the compound is characterized and confirmed by methods including 1H-NMR, 13C-NMR, HRMS, single-crystal X diffraction, and the like. The method comprises the following steps of: under the catalytic condition of silver triflate and N-heterocyclic carbene, carrying out one kettle method of series intramolecular cyclization and polarity reversal addition reaction on o-alkynyl phenyl hydrazone and alpha, beta-unsaturated aldehyde in tetrahydrofuran, methanol and alkali to efficiently prepare the 2-amino-1,2-dihydro-isoquinoline compound- a. The method has the advantages of high reaction efficiency, mild conditions, simple operation, lower cost, high product purity, convenient separation and purification and is suitable for large-scale preparation. The skeleton structure of the product has wide spectrum biological activity, and the compound has wide application prospect in discovery of new drugs.
Owner:FUDAN UNIV

Compound based on chiral binaphthol-terpyridyl platinum and preparation method of compound

ActiveCN110655537AHas near-infrared circularly polarized luminescent propertiesEasy to purifyOrganic chemistry methodsPlatinum organic compoundsPotassium tetrachloroplatinateAlpha-naphthol
The invention discloses a compound based on chiral binaphthol-terpyridyl platinum and a preparation method of the compound. The preparation method comprises the steps: dissolving a compound BT in a first solvent and stirring to form a first solution; dissolving potassium chloroplatinite in a second solvent, and stirring to form a second solution; adding the second solution into the first solution,and carrying out heating reflux to obtain BTPt-Cl; dissolving silver trifluoromethanesulfonate and the BTPt-Cl in a third solvent, and carrying out heating reflux to obtain BTPt-OTf. The invention discloses the compound based on chiral binaphthol and terpyridyl platinum and a preparation method of the compound; the compound based on chiral binaphthol and terpyridyl platinum, having an aggregation-induced near-infrared circular polarization luminescence property and having a highest luminescence asymmetry factor up to 10<-1> is prepared through two-step synthesis. The method has the advantagesof low synthesis cost, simple synthesis route and easiness in product purification, and the synthesized target compound has the axial chiral structure of binaphthol and the fluorescence characteristic of terpyridyl platinum, and has the aggregation-induced luminescence property.
Owner:NANJING FORESTRY UNIV

Beta-carbonyl-(alpha-cyanoimine) compound and synthesis method thereof

The invention relates to a beta-carbonyl-(alpha-cyanoimine) compound and a synthesis method thereof, wherein the compound has a structural formula defined in the specification, R<1> is hydrogen, methyl, methoxy, ester, fluorine, chlorine, bromine, alkenyl or alkynyl (C2-C3), R<2> is hydrogen or methyl, and R<3> is hydrogen or methyl. According to the present invention, the beta-carbonyl-(alpha-cyanoimine) compound is a valuable organic synthesis intermediate, wherein the carbonyl cyanoimine skeleton exhibits various reaction activities, such that the beta-carbonyl-(alpha-cyanoimine) compound can be converted into other corresponding active compounds; the raw materials used in the method are simple and easy to obtain, and t-butyl isocyanide is used as the cyano source of the reaction, and has the best reactivity and the best substrate adaptability under the promotion of silver trifluoromethanesulfonate; and the conventional reaction solvent is used during the reaction process, and the method has characteristics of simple operation, mild condition, environmental protection and general-to-excellent yield, and has good development prospect in industrial production.
Owner:SHANGHAI UNIV

1,2-dihydroisoquinoline derivative and preparation thereof

The invention discloses a 1,2-dihydroisoquinolin derivative and a preparation method thereof, relating to a midbody which can be used for synthesizing natural alkaloid and a preparation method thereof. The 1,2-dihydro-isoquinolin derivative has a structure of formula (I). In the formula, R1 is meta-position or ortho-position substituted electron donating or weak electron-withdrawing aromatic group or H; R2 is methyl or ethyl; R3 is hydrogen or alkyl; and R4 is meta-position or ortho-position substituted aromatic group. The mol ratio of diazonium, alcohol (or water), imine, rhodium acetate and silver trifloromethanesulfonate is 1.2:1.2:1:0.01:0.05. A solvent, the alcohol (or water), the imine and a catalyst are used for preparing a mixed solution. Then, the diazonium is evenly mixed with another solvent to prepare diazonium solution which is then infused into the mixed solution. The solvent is removed by reduced pressure distillation at a temperatre of 40-70 DEG C. Column chromatographic separation is carried out to obtain the pure product of the 1,2-dihydro-isoquinolin derivative. When the 1,2-dihydro-isoquinolin undergoes reduction reaction, a tetrahydroisoquinoline derivative with pharmaceutical activity can be generated. The 1,2-dihydroisoquinolin derivative is an important structural unit of a great number of natural products and can be used as a midbody which can be used for synthesizing natural alkaloid.
Owner:EAST CHINA NORMAL UNIV

Axially chiral biaryl compound with P-stereo center and synthesis method and application thereof

The invention discloses an axially chiral biaryl compound with a P-stereo center and a synthesis method and application thereof. The structural formula of the compound is shown in the specification, chiral trivalent rhodium [CpXRh(III)] is used as a catalyst, diaryl phosphonamide and diaryl acetylene are used as raw materials, and enantioselective coupling is conducted under the assistance of silver trifluoromethanesulfonate or silver hexafluoroantimonate and silver acetate to obtain the compound. Diarylacetylene is taken as an initial raw material, the compound is stable in property and easy to prepare, but the compound is seldom applied to arylation reaction. In the prior art, aryl arylation is mainly carried out by using brominated aromatic hydrocarbon, arylboronic acid and the like. The simple diarylacetylene is adopted as an arylation reagent, the axially chiral biaryl and the P-center chiral compound are stereoscopically and specifically synthesized through double activation of C-H bonds in the aryl phosphonamide and the diarylacetylene, and the method has the advantages of being mild in reaction condition, high in enantioselectivity, good in diastereoselectivity and the like.
Owner:SHAANXI NORMAL UNIV

6-(alpha-cyanoimine) based phenidine compound and synthesis method thereof

The invention relates to an alpha-cyanoimine substituted phenidine compound. A structural formula of the compound is shown as follows. The compound is an organic synthesis intermediate of great value,a phenidine framework already shows diverse bioactivity, so that the compound can be converted into corresponding other active compounds. The method is simple and easy-to-get in raw material, t-butylisonitrile is adopted as a cyano source of reaction, and high reaction activity is presented under catalysis of silver trifluoromethanesulfonate; the reaction process is simple in operation, mild in condition, environment-friendly and common to moderate in yield, therefore, the compound has great development prospect in industrial production.
Owner:SHANGHAI UNIV

Iridium complex electroluminescent material, preparation method thereof and electroluminescent device thereof

The invention discloses an iridium complex electroluminescent material, and the structural formula is shown in the specification. A preparation method comprises the following steps: under the protection of nitrogen, carrying out a heating reaction on a compound A and iridium trichloride trihydrate to generate B, carrying out a reaction on the B and silver trifluoromethanesulfonate to generate C, and finally, carrying out a reaction on the C and a compound D to obtain the iridium complex electroluminescent material. The invention also discloses an organic electroluminescent device containing the iridium complex electroluminescent material, the organic electroluminescent device comprises a first electrode, a second electrode and one or more organic matter layers arranged between the first electrode and the second electrode, and the organic matter layers contain the iridium complex electroluminescent material. According to the iridium complex electroluminescent material, a specific heterocyclic ligand is selected for combination, the wavelength of the compound is adjusted, and after the obtained iridium complex electroluminescent material is used for an organic electroluminescent device, the luminous efficiency of the device is improved, and the service life is prolonged.
Owner:JILIN OPTICAL & ELECTRONICS MATERIALS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products