325 results about "Isocyanide" patented technology

There is disclosed herein phosphorescent compounds, uses thereof, and devices including organic light emitting diode (OLEDs) including such compounds. Compounds of interest include: wherein A is Os or Ru The anionic chelating chromophores NˆN, which are formed by connecting one pentagonal ring structure containing at least two nitrogen atoms to a hexagonal pyridine type of fragment via a direct carbon-carbon linkage. L is a neutral donor ligand; the typical example includes carbonyl, pyridine, phosphine, arsine and isocyanide; two neutral L's can also combine to produce the so-called chelating ligand such as 2,2′-bipyridine, 1,10-phenanthroline and N-heterocyclic carbene (NHC) ligand, or bidentate phosphorous ligands such as 1,2-bis(diphenylphosphino)ethane, 1,2-bis(diphenylphosphino)benzene. L can occupy either cis or trans orientation. When L occupies the trans position, the preferred structure contains both the hexagonal fragment of NˆN as well as its pentagonal fragment located at the trans position respect to their counterparts of the second NˆN chromophore. When L occupies the cis position, the preferred structure consists of the pentagonal unit of NˆN chromophores residing opposite to the L. X,1 X2 and X3 independently are C or N; when X2 is N, R1 is omitted, when X3 is N, R2 is omitted, R1 is H, C1-C8 alkyl, C1-C8 substituted phenyl or C1-C4 perfluoroalkyl, R2 is H, F or cyano substituent, X4 is either C or N; X4 may locate at any position of the hexagonal ring, when X4 is N and R3 and R4 are not linked to X4, R3 is H, methyl or C1-C3 small alkyl, R4 is H, methyl or C1-C3 small alkyl, or R3 and R4 together form an additional conjugated unit with structure

The invention discloses a double-hindered phenol structure-contained hydrazides compound for a light stabilizer and a preparation method thereof. The double-hindered phenol structure-contained hydrazides compound has a double-hindered phenol and double-hydrazide structure, thus, the molecular weight is increased, and the migration resistance and thermal oxidation resistance capacity is strong. The preparation method comprises the following steps: performing addition reaction on hindered phenols and alpha, beta-acrylic ester under the action of a catalyst to obtain an addition product, wherein the molar ratio of the hindered phenols to the alpha, beta-acrylic ester is 1.0:(0.6-1.8), and the catalyst is alkali metal, an alkali metal hydroxide, an alkali metal hydride or an alkali metal alcoholate; then, performing carbonyl nucleophilic substitution reaction on the addition product and a hydrazine hydrate in an organic solvent A to obtain a hydrazides substitution product, wherein the molar ratio of the addition product to the hydrazine hydrate is 1.0:(0.8-5.0); performing the reaction between a diisocyanate compound and the hydrazides substitution product at the temperature of 0-10 DEG C; and carrying out recrystallization to obtain a goal product. By adopting the preparation method disclosed by the invention, the operation is simple, the raw materials are available, and the cost is low.

A method of synthesizing alpha-sulfonamido amide, carboxylic acid or hydroxamic acid derivatives comprising providing a set of polymer-bound reactant(s) (sulfonamide, aldehyde or ketone, isocyanide or acid) to react with three sets of the other three reactants to form an array of polymer-bound alpha-sulfonamido amide-type intermediates and use of such intermediates for the preparation of combinatorial libraries.

The invention relates to a multi-responsive polymer nanocarrier with a rapid cell penetrating characteristic. The nanocarrier is formed by self-assembling of a multi-responsive amphipathic triblock copolymer, the nanocarrier adopts an onion structure sequentially comprising an acid-responsive PLLA core, cyanine molecules with a near infrared absorption characteristic, a hydrogen-peroxide-responsive PPI (polyphenyl isocyanide) intermediate layer and a left-handed spiral hydrophilic PPI hydrophilic chain from inside to outside sequentially, wherein the structure of the multi-responsive amphipathic triblock copolymer is shown in the general formula in the specification, R1 is a group with stimulation responsiveness, and R2 is a chiral PEG hydrophilic chain; x ranges from 20 to 50, y ranges from 20 to 50, and z ranges from 30 to 80. The multi-responsive polymer nanocarrier can be used for transporting hydrophobic dye molecules and medicine molecules, can rapidly and efficiently penetrate cell membranes, has multiple stimuli-responsiveness, realizes programmable controlled release of medicines and has a chemical-photothermal collaborative treatment characteristic.

The invention discloses an optically-active helix chain poly(phenyl isocyanide) and a polymerization method thereof. The polymerization process is shown as the general formula in the description; in the formula, the structural formula of a chiral phosphine ligand is shown in the description. A palladium catalyst is adopted, the chiral phosphine ligand (S-or R-BINAP) is added to induce polymerization of achiral phenyl isocyanide, and the optically-active polymer with excessive one-handed helixes is obtained; obtained poly(phenyl isocyanide) has a high molecular weight and narrow molecular weight distribution.

Disclosed are: a method for production of a polyisocyanide derivative having a stable helical main chain structure with a right-handed or left-handed helix or a mixture thereof from a single type of monomer by polymerizing an aromatic isocyanate having a substituent harboring a structure —CONH in the aromatic ring and a hydrophobic moiety having 6 or more carbon atoms in a polymerization solvent, wherein the direction of the helix depends on the polarity of the polymerization solvent; a poly(aromatic isocyanide) derivative produced by the method; and an aromatic isocyanide which is useful as a monomer for use in the production of the poly(aromatic isocyanide) derivative.

The invention provides an aminodiacyloxylamide derivative which has bactericidal activity and contains an amino group. The general formula of the aminodiacyloxylamide derivative is represented as (I), wherein R1 is a methyl group, an ethyl group and an isohexyl group; R2 is chlorine, an isooctyl group and an n-heptyl group; and R3 is hydrogen or chlorine. A preparation method includes the steps of: 1) performing a reaction to azide-carboxylic acid and keto-aldehyde and isonitrile at 30 DEG C, reaction solvent being water; 2) after the reaction is carried out for 24 h, adding triphenylphosphine, continuously performing the reaction for 2-5 h; and 3) after the reaction is finished, extracting the reaction liquid with dichloromethane, drying the reaction liquid and removing the solvent, dichloromethane, under reduced pressure, and performing column chromatography to the residual substance to produce the target compound (I). The compound has good inhibition activity on penicillium digitatum and penicillium italicum, and can be used as a bactericide.

The invention relates to an ablative black film for directly making a plate by a flexographic plate computer and a preparation method of the ablative black film. The ablative black film is characterized by comprising at least one type of nano carbon black particles, one infrared laser ablative dye and two polymer adhesives, a polyether polyurethane compound modified by the first polymer adhesive polyamide and the second polymer adhesive single isocyanate, and a super dispersing agent with the structural formula of R1-X-(CH2CH2O)p-(CHCH3CH2O)q-R2. The laser ablative black film prepared by the method has high sensitivity and good film forming property and is difficult to wrinkle.

Disclosed is a method of preparing a composition comprising a compound represented Structural Formula (I): The method comprises the step of reacting an aldehyde compound R10CHO with an isonitrile compound represented by Structural Formula (II):

There is disclosed herein phosphorescent compounds, uses thereof, and devices including organic light emitting diode (OLEDs) including such compounds.Compounds of interest include:wherein A is Os or RuThe anionic chelating chromophores N̂N, which are formed by connecting one pentagonal ring structure containing at least two nitrogen atoms to a hexagonal pyridine type of fragment via a direct carbon-carbon linkage.L is a neutral donor ligand; the typical example includes carbonyl, pyridine, phosphine, arsine and isocyanide; two neutral L's can also combine to produce the so-called chelating ligand such as 2,2′-bipyridine, 1,10-phenanthroline and N-heterocyclic carbene (NHC) ligand, or bidentate phosphorous ligands such as 1,2-bis(diphenylphosphino)ethane, 1,2-bis(diphenylphosphino)benzene.L can occupy either cis or trans orientation.When L occupies the trans position, the preferred structure contains both the hexagonal fragment of N̂N as well as its pentagonal fragment located at the trans position respect to their counterparts of the second N̂N chromophore.When L occupies the cis position, the preferred structure consists of the pentagonal unit of N̂N chromophores residing opposite to the L.X,1 X2 and X3 independently are C or N;when X2 is N, R1 is omitted,when X3 is N, R2 is omitted,R1 is H, C1-C8 alkyl, C1-C8 substituted phenyl or C1-C4 perfluoroalkyl,R2 is H, F or cyano substituent,X4 is either C or N;X4 may locate at any position of the hexagonal ring, when X4 is N and R3 and R4 are not linked to X4,R3 is H, methyl or C1-C3 small alkyl, R4 is H, methyl or C1-C3 small alkyl, or R3 and R4 together form an additional conjugated unit with structure

The invention relates to a preparation method of cefcapene diisopropylamine salt. The preparation method comprises the following steps: (1) obtaining acylate 3 by using cefcapene side chain acid 2 in the presence of an acylation reagent namely SOCl2 and an acid-binding agent namely triethylamine; (2) obtaining a condensation product 5 by using acylate 3 and a 7-HACA raw material 4 in the presence of triethylamine and a catalyst namely 4-dimethylaminopyridine; (3) enabling the condensation product 5 to react with chlorosulfonic acid isocyanate to obtain a 3-bit aminoacyl ester compound 6; (4) performing salt formation on the compound 6 and diisopropylamine to obtain cefcapene diisopropylamine salt 1. According to the preparation method disclosed by the invention, thionyl chloride is used as the acylation reagent, and triethylamine is used as the acid-binding agent so as to reduce the cost; 4-dimethylaminopyridine with the catalyst amount is added in the step (2) to ensure that the reaction is performed more completely and the reaction time is shortened; the preparation method is simple and convenient in whole route operation, and is convenient for large-scale production.

The invention discloses a polythiourea compound and a preparation method and application thereof. The method comprises the following steps: reacting an amine compound monomer, an isonitrile compound monomer and carbon disulfide in an organic solvent, and carrying out post-treatment to obtain the polythiourea. The monomers used in the invention are all industrial raw materials, the cost is low, and large-scale gram-level production can be carried out; the utilization rate of reaction atoms is 100%, and no toxic or harmful by-product is generated; the reaction can be carried out under the conditions of room temperature and air, the operation is simple, and the polymerization reaction yield is high; the product is easy to separate, and a polythiourea product and another thioformamide product can be obtained in one pot; symmetrical polythiourea, asymmetrical polythiourea with a controllable sequence and polythiourea with a disordered structure can be prepared by adjusting the feeding type, mode and proportion; the obtained series of polythiourea also has excellent self-repairing performance and luminescence performance, can be applied to the field of self-repairing and the field of photoelectric devices, and promotes further development of polythiourea compounds.

The invention discloses a 2-phenyl-3-(toluenesulfonylmethyl) imidazo[1,2-a] pyridine compound and a preparation method thereof. The preparation method comprises the following steps: adding 2-phenyl-imidazo [1,2-a] pyridine compound and p-tolylsulfonylmethyl isocyanide into a reaction tube in an argon environment, adding ferric trichloride, then adding a green solvent, and reacting for 18 to 48 hours at 80 to 120 DEG C; and after the reaction, extracting, chromatographically separating, and drying to obtain a target product. In the reaction, cheap metal ion (III) is used as a catalyst, water and polyethylene glycol 400 are used as reaction solvents, the sulfonylmethylation reaction of the imidazo [1,2-a] pyridine compound and p-tolylsulfonylmethyl isocyanide is realized, sulfonyl of the obtained compound is used as a leaving group, and the further functional group reaction is realized. The method has important significance on the research and application of the sulfonylmethylation reaction of the imidazo [1,2-a] pyridine compound.