43 results about "Diisopropylamine" patented technology

The invention belongs to the technical field of organic synthesis, and particularly relates to an improved gemfibrozil intermediate preparation method which comprises the following steps: S1, adding metal lithium and diisopropylamine into an organic solvent, cooling to 0-5 DEG C, adding a catalyst, carrying out ultrasonic-assisted reaction, heating to 8 DEG C, and continuing ultrasonic treatment; and S2, after the reaction of the metal lithium in the step S1 is finished, controlling the system temperature, then slowly dropwise adding isobutyl isobutyrate, carrying out heat-preservation stirring, dropwise adding 1, 3-bromochloropropane or 1, 3-dibromopropane, carrying out a heat-preservation reaction after the dropwise adding is finished, carrying out a quenching reaction after the reaction is finished, carrying out liquid separation, washing with water, carrying out reduced pressure distillation on an organic phase, and collecting fractions, thereby obtaining the product. According to the preparation method provided by the invention, by optimizing reaction conditions and a post-treatment process, the process flow is simplified, the generation of byproducts and impurities is effectively reduced, the final product is ensured to be high in purity and few in impurities, and the yield is high and can reach 95% or above.

The invention discloses a photocatalyst as well as preparation and application thereof, and belongs to the field of photocatalytic materials, and a preparation method of a porous photocatalyst based on nitrogen heterocyclic rings comprises the following steps: dispersing a parent unit (nitrogen heterocyclic ring molecules) and 1, 4-diacetylene benzene into N, N-dimethylformamide and diisopropylamine, and then quickly adding the catalyst; reacting at 60 to 180 DEG C for 60 to 180 hours; and after the reaction is finished, carrying out suction filtration, stirring and washing a filter cake with a solvent for 1-4 hours, carrying out suction filtration, repeatedly washing and carrying out suction filtration, and carrying out vacuum drying on the filter cake to obtain the nitrogen heterocyclic ring-based porous photocatalyst. The method provided by the invention has the advantages that the preparation conditions are easy to control, the method is environment-friendly, the process is simple and the operation is convenient, and the obtained material not only has high thermal stability, but also shows excellent photocatalytic performance and can be used for efficiently producing hydrogen peroxide. According to the technology, the production efficiency of hydrogen peroxide is improved, the influence on the environment is reduced, and the requirement for sustainable development of the modern chemical industry is met.

The invention discloses a fesoterodine intermediate preparation method, and belongs to the technical field of chemical medicine raw material medicine synthesis, 6-(hydroxymethyl)-4-phenylchroman-2-ol and diisopropylamine are used as starting materials to prepare a fesoterodine intermediate, an inert conversion reagent is used, and the reaction temperature is controlled to be 30-60 DEG C, so that the fesoterodine intermediate is obtained. On the other hand, the excessive diisopropylamine reacts with an inert conversion reagent, the excessive diisopropylamine is converted into an excessive state which does not react with the product, and the excessive diisopropylamine is prevented from reacting with the product to generate a large amount of various impurities; a reducing agent and an inert conversion reagent are introduced to be combined, so that the problem of impurity generation caused by palladium catalytic hydrogenation reduction is avoided.

The invention provides a preparation method of N, N-diisopropylethylamine based on a liquid-phase compression synthesis process, which comprises the following steps: mixing ethanol with hydrobromic acid with specified concentration, and carrying out reactive distillation treatment in the presence of a phase transfer catalyst to generate bromoethane; p-bromoethane and diisopropylamine are subjected to a liquid phase addition and compression combination reaction, and a reaction mixture is obtained; and sequentially neutralizing, distilling, condensing and filtering the reaction mixture to obtain the N, N-diisopropylethylamine, so as to solve the problems that the existing preparation method of the N, N-diisopropylethylamine is high in energy consumption, high in operation risk, large in pollutant discharge amount, low in by-product resource utilization rate, low in cost and the like. The safety is poor; the energy efficiency is low; and by-products cannot be recycled.

The invention discloses a method for synthesizing a dithio alkyl ketone compound by using diisopropylamine, which is characterized in that diisopropylamine is used as alkali, a cycloalkyl peroxy alcohol compound and a tetrasulfide compound are driven by illumination to generate a free radical coupling reaction, and the dithio alkyl ketone compound is successfully synthesized. The preparation method provided by the invention has the advantages of easily available raw materials and simple operation, has excellent functional group compatibility, can meet the synthesis requirements of target products with different structures, and has significant practical application value.

The presently claimed invention relates to an alkaline composition for cleaning a substrate comprising i) copper or copper alloy and ii) cobalt or cobalt alloy, the composition comprising: a) at least one pH adjustor selected from diglycolamine, 4,4-diethoxy-N,N-dimethyl-1-butanamine, 3-dimethylaminopropan-1-ol, dimethylaminoethoxyethanol, N,N-dimethylisopropanolamine, ethylethanolamine, N-methyldiethanolamine, 2-(2-(methylamino)ethoxy)ethanol, 3-(methylamino)propane-1,2-diol, 2-[2-[2-(2-methoxy- ethoxy)ethoxy]ethoxy]ethylamine, 2-[2-(2-aminoethoxy)-ethoxy]-ethanol, N-butyldiethanolamine, diisopropanolamine, N-methyldiisopropanolamine, monoethanolamine, 3-dimethylamino-1,2-propandiol, 2- amino-1-butanol, 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethanol, prolinol, 1-methyl-2-pyrrolidinemethanol, 1-methyl-2-pyrrolidinemethanol, 1-methyl-3-pyrrolidinol, 2-amino-2-methyl-1-propanol, N,N-dimethylethanolamine, butylethanolamine, diethylethanolamine, 3-methoxypropylamine, 4-(2-hydroxyethyl)morpholine, 4-(dimethylamino)cyclohexanol, 2-amino-2-methyl-1, 3-propanediol, or diisopropylamine; b) at least one complexing agent selected from C2 to C12 hydrocarbon having at least two sulfonic acid or carboxylic acid groups; c) at least one polymeric dispersing agent having a weight average molecular weight ≥ 1000 g / mol; and d) a solvent comprising water.

The invention belongs to the technical field of pharmacy, and relates to a method for recovering effective components from ampicillin sodium crystallization mother liquor, which comprises the steps of diisopropylamine recovery, ampicillin trihydrate acid recovery and sodium isooctanoate recovery. According to the method, the diisopropylamine, the ampicillin trihydrate and the sodium isooctanoate are effectively recovered from the solvent-method ampicillin sodium crystallization mother liquor, the recovery rates of the diisopropylamine, the ampicillin trihydrate and the sodium isooctanoate recovered by the method are all higher than 80%, and the quality of the recovered product is good. According to the method, various effective components of the ampicillin sodium crystallization mother liquor are effectively recovered, the production cost can be greatly reduced, meanwhile, the discharge amount of sewage is reduced, and the economic benefits and social benefits of enterprises are improved.

The present invention provides a preparation method and application of a sulfonated photocatalyst, belonging to the technical field of photocatalyst materials. The preparation steps include: reacting 2,5-dibromopyrimidine with trimethylsilylacetylene in anhydrous triethylamine and tetrahydrofuran, followed by extraction and purification to obtain a first intermediate; dissolving the first intermediate in tetrahydrofuran, dropping tetrabutylammonium fluoride for hydrolysis at a temperature below -40 °C, followed by extraction and purification to obtain a second intermediate; dissolving the second intermediate and 5,10,15,20-tetra(4-bromophenyl)porphyrin in N,N-dimethylformamide and diisopropylamine, and carrying out a Sonogashira coupling reaction under catalytic action; after the coupling reaction is completed, filtering, extraction and vacuum drying are carried out to obtain an initial polymer. The preparation method of the sulfonated photocatalyst provided by the present invention is simple, efficient and environmentally friendly. The prepared sulfonated photocatalyst has both excellent hydrophilicity and high oxygen adsorption capacity, and can efficiently produce H2O2.

The invention relates to a preparation method of diisopropylamine silane, which comprises the following steps: (1) reacting dichlorosilane with diisopropylamine to obtain diisopropylamine chlorosilane; and (2) carrying out a reaction on the diisopropylamine chlorosilane obtained in the step (1) and lithium hydride to obtain the diisopropylamine silane. The preparation method of diisopropylamine silane in the prior art is optimized, a complex catalyst does not need to be prepared in advance, raw materials are simple and easy to obtain, reaction steps are simple, high-temperature and high-pressure reaction conditions are avoided, the reaction conditions are mild, the obtained target product has high yield and purity, and industrial large-scale production is facilitated.

Present invention relates to a method for producing green fluorescent paint for use as a lighting for energy-efficient highway lane and park markings, characterized as comprising following production steps; adding 9,10-dibromoanthracene, CuI, Pd catalyst, diisopropylamine and toluene in a reaction flask under nitrogen atmosphere and stirring them on a magnetic stirrer, adding tetraphenylsilanacetylenyl to the mixture and performing reflux distillation by increasing the reaction temperature, after 24 hours bringing the temperature to room temperature, obtaining pure product from the mixture brought to room temperature using column chromatography, taking 0-1% by mass of the product and mixing it in resin and an aromatic solvent for 6-24 hours.

The invention discloses a closed type polyisocyanate composition with stable storage and a preparation method and application thereof, the closed type polyisocyanate composition comprises a structure I, a structure II, a structure III and a structure IV, A represents a gel chromatography (GPC) integral area percentage of the structure I; b represents the gel chromatography test GPC integral area percentage of the structure II, C represents the gel chromatography test GPC integral area percentage of the structure III, and D represents the gel chromatography test GPC integral area percentage of the structure IV; wherein A / (A + B + C + D) = 0.15-0.25, and B / (A + B + C + D) = 0.30-0.45. The water-based polyurethane adhesive contains terminated polyisocyanate which is obtained by carrying out a reaction on a hexamethylene diisocyanate polymer, diethyl malonate and diisopropylamine. The composition is clear and transparent after being stored for 12 months at normal temperature.

The invention relates to the technical field of membrane separation, in particular to a mixed matrix membrane and a preparation method and application thereof. The mixed matrix membrane comprises a polymer matrix and a filler dispersed in the polymer matrix, the filler comprises an MOF material and MA compound amine loaded on the MOF material; the MA compound amine is selected from one or more of ethanolamine, methyl monoethanolamine, diethanolamine, N-methyldiethanolamine (MDEA), diisopropylamine, hydroxyethyl ethylenediamine and 2-amino-2-methyl-1-propyl alcohol. The preparation method comprises the following steps: adding the MA compound amine into a reaction kettle; the mixed matrix membrane has high selectivity and high permeability, and is suitable for large-scale continuous preparation.

The application discloses an ionic liquid containing a boron-containing oxygen ring and a benzene ring, a preparation method and application, and the ionic liquid is obtained by the reaction of tris(trimethylsilyl) borate, dichloroethylene, 4-p-chlorophenyl imidazoline and diisopropylamine; the ionic liquid can be used for alcoholysis of PET to obtain DMT, improve the conversion rate of DMT, and has a significant prospect in the application of PET degradation and recycling of DMT.

The invention discloses a membrane permeation-pressurized rectification coupling process of a diisopropylamine-isopropanol ternary water-containing system, which comprises the following steps: primarily separating by an azeotropic rectification tower to obtain a diisopropylamine-isopropanol-water homogeneous ternary mixture at the tower top, and cooling by a cooler to obtain a ternary mixture; conveying to a membrane dehydration assembly to selectively remove moisture; and the dehydrated diisopropylamine-isopropanol mixture enters a pressurized rectifying tower, so that high-purity recovery of diisopropylamine and isopropanol is realized. The process does not need to introduce a third component, equipment is simple, the recovery purity is high, meanwhile, chemical pollution is avoided, and the environmental protection requirement is met.

The present invention relates to a nitrogen-containing heterocyclic derivative of rupestonic acid amide, its preparation method and use. The synthesis of this type of derivative is to first react rupestonic acid with nitrogen-containing heterocyclic compounds with different substitutions under the conditions of diisopropylamine and 2-(7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate to obtain 1-20 nitrogen-containing heterocyclic derivatives of rupestonic acid amide. The reaction conditions of this method are mild and the experimental steps are simple. The anti-tumor activities of the obtained 1-20 nitrogen-containing heterocyclic derivatives of rupestonic acid amide were tested on four types of cancer cells, namely Hela (human cervical cancer cells), HT-29 (human colon cancer cells), A549 (human non-small cell lung cancer cells) and HepG2 (human liver cancer cells). The experimental results show that compounds 1, 3, 14, 17, 18 and 19 are useful in the preparation of anti-tumor drugs.

The invention belongs to the technical field of preparation of artemisinin, and discloses a preparation method of artemisinin, which comprises the following steps: reacting diisopropylamine with n-butyllithium in anhydrous THF (tetrahydrofuran) to generate strong base lithium diisopropylamide and obtain a strong base lithium diisopropylamide solution; step 2, then adding a mixed solution of artemisinin and THF into the strong base lithium diisopropylamide solution; the strong base lithium diisopropylamide is used as a strong base to capture specific acidic hydrogen in artemisinin molecules to form an enol salt intermediate; benzene sulfonyl chloride is added to react with hydroxyl of the enol salt intermediate to generate sulfonate; taking a sulfonate group as a good leaving group, carrying out beta-elimination under an alkaline condition to form a double bond, reacting to obtain an artemisinin solution, and purifying the artemisinin solution to obtain a pure product artemisinin; according to the method, benzenesulfonyl chloride and artemisinin which are low in price and easy to obtain are used as main raw materials, the artemisinin is synthesized through a one-pot method, and the method is simple in process, environmentally friendly, high in yield and suitable for industrial production.

The present invention discloses the use of a chlorine-free catalyst in the preparation of diisopropylaminosilane. The chlorine-free catalyst comprises calcium bis(hexamethyldisilazide) and / or strontium bis(hexamethyldisilazide) and diisopropylaminosilane is prepared by a dehydrogenative coupling reaction of monosilane with diisopropylamine catalyzed by a chlorine-free catalyst. The present invention uses a low-cost chlorine-free compound, calcium bis(hexamethyldisilazide) and / or strontium bis(hexamethyldisilazide), as a new catalyst to prepare diisopropylaminosilane, which can effectively catalyze the dehydrogenative coupling reaction of monosilane and diisopropylamine to synthesize diisopropylaminosilane in one step in a yield of 40-65% for diisopropylaminosilane.

The application discloses SAPO-18-MeR molecular sieve and a preparation method and application thereof. The anhydrous chemical composition of the molecular sieve is mMe*nR(Si x Al y P z )O2; Me is at least one selected from Li + , Na + , K + and NH4 + ; R is at least one selected from N, N-diisopropyl ethylamine, tetraethyl ammonium hydroxide, triethylamine, diisopropylamine, diethylamine and ethylenediamine; m is the mole number of Me, m=0.05-0.2; n is the mole number of R, n=0.05-0.2; x is the mole fraction of Si, x=0.05-0.35; y is the mole fraction of Al, y=0.35-0.55; z is the mole fraction of P, z=0.25-0.45, and x+y+z=1. The molecular sieve has excellent silicon distribution and strong acid property, and has excellent catalytic performance as a denitration catalyst after loading Cu ions.

The invention relates to the technical field of medical intermediates, and provides a synthesis method of 7-bromo-8-fluoro-6-(trifluoromethyl) quinazoline-2, 4 (1H, 3H)-diketone, which comprises the following steps: S1, by taking 2-fluoro-4-trifluoromethyl benzoic acid as a raw material, adding Br2 under the conditions of a lithium reagent and diisopropylamine, and reacting to obtain a compound A; s2, adding tert-butyl alcohol, triethylamine and diphenyl azide phosphate into the compound A, and reacting to obtain a compound B; s3, the compound B and N-iodosuccinimide are subjected to a heating reaction, and a compound C is obtained; s4, adding the compound C into dimethylformamide, adding CuCN, and reacting to obtain a compound D; and S5, reacting the compound D with urea to obtain the product. Through the technical scheme, the problems of long synthetic route and low yield of the 7-bromine-8-fluoro-6-(trifluoromethyl) quinazoline-2, 4 (1H, 3H)-diketone in related technologies are solved.

The application provides a MWW structure molecular sieve and a preparation method and application thereof. The preparation method comprises the following steps: mixing an aluminum source, water, an alkali source, a first template agent, a second template agent, a silicon source and seeds to form a gel, and crystallizing the gel to obtain the MWW structure molecular sieve; wherein the first template agent comprises cyclohexylamine, and the second template agent comprises at least one of diisopropylamine, di-n-butylamine, diisobutylamine, 1,4-diazabicyclo[2.2.2]octane, 1,6-hexanediamine and N,N,N,N-tetramethyl-1,6-hexanediamine. The application further provides the MWW structure molecular sieve prepared by the above preparation method and the application of the MWW structure molecular sieve. According to the application, the MWW structure molecular sieve can be directly synthesized without using hexamethyleneimine, piperidine and homopiperazine by the method of seed and two template agents assisting crystallization.

The invention discloses a preparation method and application of a low-silicon SAPO-34 molecular sieve. Comprising the following steps: mixing an aluminum source, a phosphorus source, a silicon source, a template agent R1, a template agent R2 and water to obtain initial gel, wherein the molar ratio of Al2O3 to P2O5 to SiO2 to R1 to R2 to H2O in the initial gel is 1.0: (0.5-3.0): (0.01-0.3): (0.5-8.0): (0.01-2.0): (20-200); r1 is at least one of diethylamine, triethylamine, di-n-propylamine, diisopropylamine, n-butylamine, morpholine, cyclohexylamine, piperazine and tetraethylammonium hydroxide; r2 is at least one of diethylenetriamine, triethylene tetramine, tetraethylenepentamine, pentaethylenehexamine and polyethylene polyamine; heating and crystallizing the initial gel under a closed condition to obtain a crystallized product; and separating and drying the crystallized product to obtain the molecular sieve. The method is simple in process, good in repeatability and beneficial to large-scale industrial production.

The invention relates to the technical field of synthesis of novel compounds, and discloses a quinazolinone-triazene compound and a preparation method and application thereof.A triazene group based on dimethylamine, diethylamine, diisopropylamine, morpholine ring or 4-methylpiperidine ring is introduced to a quinazolinone parent through a diazotization reaction, and the quinazolinone-triazene compound is obtained. The quinazolinone-triazene compound with a brand new structure is designed and synthesized, the synthesis route is short, the preparation method is simple, the raw materials are easy to obtain, the cost is low, and the yield is high. The compounds have certain inhibitory activity on gram-positive bacteria, gram-negative bacteria and fungi (including clinical drug-resistant bacteria), can be used for preparing antibacterial or antifungal drugs, and can also be used for DNA intercalating agents, bactericides and antitumor drugs. The preparation raw materials are high in commercialization degree, cheap and easy to obtain, the preparation route is short, and the method is simple.

The present invention relates to a ready-to-use liquid pest control composition comprising: at least one trisiloxane surfactant of formula (I), at least 40 wt% water, and at least one hydrolysis-preventing compound selected from at least one bulky base with steric hindrance, tocopherol, and combinations thereof, wherein the bulky base with steric hindrance is selected from the group consisting of alkali metal bicarbonates, trialkylamines, trialkanolamines, 2-tert-Butyl-1,1,3,3- tetramethylguanidine, lithium diisopropylamine, alkali metal tert-butoxide, and combinations thereof; wherein the composition has a pH of at least 7, measured at 20°C. Formula (I) wherein: R is –(CH2)3-(OCH2CH2)nR1; R1 is -CH3, -OH, or -O(O)CCH3, and n is 2 to 25. The invention also relates to a method of immobilising and / or killing insects and to a pest control product.

The invention discloses a method for preparing cryptand-modified magnetic iron oxide nanoparticles, comprising the following steps: S1, preparing magnetic iron oxide nanoparticles; S2, preparing a cryptand compound with an R group, wherein the cryptand compound has a structure shown in Formula I; S3, dissolving the cryptand compound in tetrahydrofuran, adding magnetic iron oxide nanoparticles, copper iodide, N-ethyldiisopropylamine and sodium ascorbate, heating reaction under nitrogen protection, collecting the product after the reaction, washing and drying, and obtaining cryptand-modified iron oxide nanoparticles. The invention synthesizes cryptand-modified magnetic iron oxide nanoparticles by chemical reaction the prepared magnetic iron oxide nanoparticles and the cryptand compound, and has the beneficial effect of a simple synthesis method; the invention also discloses a cryptand-modified magnetic iron oxide nanoparticle, which has excellent adsorption and removal effect on Pb and Cd ions in rice soaking liquid.

The present application relates to the field of chemical industry, and in particular to a method for photocatalytic synthesis of diisopropylethylamine by using a bimetallic catalyst, and provides a preparation method of the bimetallic catalyst: a Pd precursor and a 3d metal salt are mixed and dissolved in deionized water, then mixed with a carrier, the pH is adjusted to 9-10, then reduced, followed by suction filtration, washing, drying, to obtain a Pd-M / TiO2 bimetallic catalyst. The present application also simultaneously provides a method for photocatalytic synthesis of diisopropylethylamine by using the bimetallic catalyst prepared by the above method: diisopropylamine and ethanol are used as raw materials, the bimetallic catalyst is used, and excitation is carried out under the irradiation of a UV lamp in an inert gas atmosphere, so as to carry out a photocatalytic reaction, and finally obtain N,N-diisopropylethylamine.

The invention discloses a preparation method and application of an MOF-PAF mixed matrix membrane, and belongs to the field of gas separation membranes. Comprising the following steps: adding N, N-dimethylformamide and N-methyldiisopropylamine into an aromatic diamine monomer under the conditions of nitrogen atmosphere and ice-water bath, then adding cyanuric chloride, and continuously stirring to react; adding a prepared MOF precursor solution, and continuously stirring and reacting to obtain a membrane casting solution; spreading the membrane casting solution on a clean glass plate, and performing thermal crosslinking in a drying oven through solvent evaporation to obtain a transparent membrane; the prepared membrane is soaked in an ammonia water / water mixed solution, deprotonation is conducted through an alkaline solution, then washing and drying are conducted, and the MOF-PAF mixed matrix membrane is obtained. The MOF-PAF mixed matrix membrane provided by the invention has the advantages of simple process and easy operation, and has good separation performance and stability for separation of H2 / CH4, H2 / N2, H2 / C3H6 and H2 / C3H8.

The invention relates to a synthesis method of disopyramide, which comprises the following steps: by taking 1-phenyl-1-formamido ethylene and 3-chloropropene as raw materials, carrying out olefin metathesis reaction to obtain a compound 2, then carrying out addition reaction on the compound 2 and 2-bromopyridine to generate a compound 3, then carrying out affinity substitution reaction on the compound 3 and N, N-diisopropylamine to obtain the disopyramide. And finally, recrystallizing with methanol to obtain the target compound. The raw and auxiliary materials used in the method are low in price, the reaction condition is mild and easy to control, the reaction route is short, the total conversion rate is high, the target product purity is qualified, and the method is suitable for industrial large-scale production.

The present invention provides carvacrol quaternary ammonium salt derivatives, their synthesis methods, and their use as antibacterial agents, belonging to the field of pharmaceutical chemistry technology. The structure of the carvacrol quaternary ammonium salt derivatives of the present invention is shown in Formula (I), where n is the number of carbon atoms between the oxygen and nitrogen atoms, and is 3, 4, or 5; and R is selected from n-propylamine, n-butylamine, n-pentylamine, n-hexylamine, dipropylamine, dibutylamine, diisopropylamine, diisobutylamine, morpholine, or thiomorpholinyl. This series of carvacrol quaternary ammonium salt derivatives exhibits excellent antibacterial activity and can be used as a potential antibacterial agent. #imgabs0#

The synthetic method comprises the following steps: under the protection of an inert atmosphere, carrying out nucleophilic substitution reaction on a compound A, potassium carbonate and deuterated bromoethane in acetonitrile to obtain a compound B; adding the compound B, the compound C, cuprous iodide and bis (triethyl phosphine) platinum iodide into chloroform and diisopropylamine, and carrying out a coupling reaction to obtain a compound D; tetra (4-ethynylbenzene) methane is taken as a core and is subjected to coupling reaction with a compound D and a compound E respectively to obtain DG1 and G1. And on the basis, deuterated rotaxane dendritic macromolecules D2G2, DG2, D1G2, D3G3, D2G3, D1G3 and DG3 with deuterated structures and completely non-deuterated rotaxane dendritic macromolecules G2 and G3 are introduced into different layers of a compound D and a compound E through repeated and alternately iterative deprotection-coupling reaction respectively, so that deuterated rotaxane dendritic macromolecules D2G2, DG2, D1G2, D3G3, D2G3, D1G3 and DG3 are introduced into different layers. The synthetic process is simple, the yield is high, and high-algebraic full-non-deuterated rotaxane dendrimer compounds and selective deuterated rotaxane dendrimer compounds can be successfully prepared.

To provide technology that suppresses freezing of a composition comprising water.SOLUTION: A freezing inhibitor for water contains diisopropylamine dichloroacetate.SELECTED DRAWING: None