74results about How to "Crystal form controllable" patented technology

The invention discloses a method for preparing nano manganese dioxides with different appearances by adjusting the reaction time only under exactly same other conditions. The method comprises the following steps of adding potassium permanganate into deionized water, and stirring to form a uniform solution in which the concentration of potassium permanganate is 0.3mol/L; then adding manganese sulfate, wherein the mass ratio of potassium permanganate to manganese sulfate is 5:2; then transferring the solution into a high-temperature high-pressure reaction kettle of which the inner container is a polytetrafluoroethylene inner container; reacting for 1-18 hours at 140 DEG C; cooling, filtering, flushing and finally drying to obtain a target product. In the method disclosed by the invention, the process is simple, the cost is relatively low, the reaction conditions are mild, and the appearance of the crystal form is controllable; the obtained product has stable quality, relatively high catalytic electrochemical activity, wide applicability and the like, and can be widely applied to lithium ion batteries, molecular sieves, catalysts, super capacitors and the like as well as the basic study of related fields.

A preparation method of up-conversion phosphor nanometer particles belongs to the technical field of materials and comprises the following steps: (1) dissolving rare-earth inorganic acid salt powder by ethanol to obtain rare-earth inorganic acid salt ethanol solution; (2) adding long-chain fatty acid, performing the reflux reaction under the mixing condition, and preparing a long-chain fatty acid precursor of rare-earth; (3) adding one of an erbium precursor, a thulium precursor and a holmium precursor as well as a yttrium precursor and a ytterbium precursor into a water-ethanol mixing system, adding and uniformly mixing sodium fluoride and surface active agent, and heating and reacting for 2-24h under the obturating condition; (4) adding organic solvent after lowering the temperature, centrifugalizing, and drying or naturally withering after washing white precipitate. The preparation method has simpler process, easy synthesis condition, good repetitiveness, low cost and higher productive rate.

The invention provides sacubitril derivatives and medicine compositions, preparation methods and application thereof and belongs to the fields of medicine compounds and preparation thereof. The sacubitril derivatives comprise sacubitril lithium salt, sacubitril kali salt, sacubitril magnesium salt, sacubitril calcium salt, sacubitril strontium salt, sacubitril zinc salt, sacubitril ferric salt, sacubitril ammonium salt, sacubitril diethylamine salt, sacubitril ethylenediamine salt, sacubitril piperazine salt, sacubitril N-(2-ethoxyl)-pyrrolidine salt, sacubitril choline salt, sacubitril cholamine salt, sacubitril diethanol amine salt, sacubitril triethanolamine salt, sacubitril tromethamine salt, sacubitril meglumine salt, sacubitril diisopropylamine salt, sacubitril tert-butylamine salt, sacubitril N, N'-bis-benzyl ethylenediamine salt, sacubitril L-lysine salt, sacubitril L-arginine salt or sacubitril L-histidine salt.

The invention belongs to the technical field of lithium sulfur batteries, and particularly relates to a preparation method of a positive electrode material of a lithium sulfur battery. The preparation method comprises the following steps: adding a carbon nano tube into a nitrogen source substance solution with the mass concentration not less than 10%, mixing uniformly, transferring into a hydrothermal/solvent thermal reaction kettle for heat preservation, cooling, and washing and drying a reaction product so as to obtain a carbon nitride nano tube; dissolving sulfur into an organic solvent so as to obtain a sulfur contained organic solution, then adding the carbon nitride nano tube obtained in the step 1 into the sulfur contained organic solution, carrying out ultrasonic dispersion for more than 0.5 hour, and performing ultrasound treatment continuously while dropwise adding an extracting agent, wherein the mass ratio of the extracting agent to the organic solvent is (0.5-10) to 1; and then drying, and carrying out freeze drying on a product after the solvent is evaporated by more than a half. Compared with the prior art, the carbon-sulfur compound obtained by the method is good in circulation stability.

The invention relates to a solid of tenofovir disoproxil. The solid is (1) a tenofovir disoproxil compound represented by a formula IV or (2) a tenofovir disoproxil cocrystal or salt represented by a formula V. The invention further relates to a preparation method for the solid of tenofovir disoproxil, a pharmaceutical composition containing the solid and application of the solid in preparation of drugs used for preventing and/or treating virus infection, especially hepatitis b virus (HBV) and/or human immunodeficiency virus (HIV) infection.

The invention relates to vonoprazan dihydrochloride, vonoprazan dihydrobromide, vonoprazan disulfate, vonoprazan nitrate, vonoprazan diphosphate, vonoprazan sulfonate, vonoprazan 1,4-hemibutanedisulfonate, vonoprazan 1,4-butanedisulfonate, vonoprazan 2-isethionate, vonoprazan L-tartrate and free alkali of vonoprazan, and crystal forms thereof. The salts and the crystal forms are simple to prepare,and the crystal forms are easy to control and has good dissolvability and stability. The invention further relates to preparation methods for the salts and the crystal forms, injections containing the salts, and application of the salts and the crystal forms to preparation of drugs used for treating and/or preventing diseases related to gastric acid.

The invention relates to a synthetic method of a polynitrogen azole zinc/cadmium framework material. The method comprises the following steps of: mixing a polynitrogen azole ligand with a metering ratio of a metal polynitrogen azole framework chemical formula, an oxide or a hydroxide with a reaction liquid, carrying out an acid-base reaction after activation, and filtering, washing and drying after the reaction to obtain the polynitrogen azole zinc/cadmium framework material. The synthetic method has mild reaction conditions, and the polymerization process of the polynitrogen azole ligand and the solid oxide or the hydroxide is accelerated by utilizing the coordination buffer action of ammonia to enable the reaction to be rapidly and efficiently finished. The method has simple operation and low production cost and does not generate any other byproducts except a required product and water, the obtained product is easy to activate, and a residual mother liquid can be directly used as the reaction liquid for the next batch of synthesis, thereby realizing continuous production and being particularly suitable for large-scale industrialized production.

A method for preparing mesoporous hydroxyapatite nanocrystal includes the following steps: weighing soluble calcium salt and phosphorus pentoxide or phosphate ester at a stoichiometric ratio of Ca/P of 1.67; respectively dissolving the phosphorus pentoxide or phosphate ester into the alcohol solution, and dissolving the soluble calcium salt into the aqueous solution, wherein the volume ratio of the aqueous solution/alcohol solution is of 2/3, 1 or 3/2; mixing the two solutions, adjusting the pH value of the mixed solutino to 9-10 with the ammonia water, and intensively mixing; feeding the solution into a reaction kettle, and carrying out the hydrothermal reaction at a temperature of 140-180 DEG C for 8 hours to obtain hydroxyapatite precipitate; washing with the distilled water, vacuum-filtering; and drying at a temperature of 200DEG C to obtain the mesoporous hydroxyapatite nanocrystal.

The invention provides a nickel cobalt oxide<@>manganese dioxide nuclear shell heterostructure nanowire array grown on carbon cloth and a preparation method and application thereof. Compared with the prior art, the product of the preparation method provided by the invention is high in purity, good in dispersibility, good and controllable in crystalline form, low in production cost and good in repeatability. The prepared nickel cobalt oxide<@>manganese dioxide nuclear shell heterostructure nanowire array grown on the carbon cloth can serve as an electrode material of a supercapacitor directly, long cycling stability, large specific capacitance, high energy density and power density are realized, and the nanowire array has a potential application value in the aspect of energy storage.

The invention provides a preparation method of a metal halide perovskite quantum dot CsSnX3. The method comprises the following steps of providing CsX, a first main solvent and a first cosolvent; after mixing, performing first heating stirring; preparing a Cs precursor; providing SnX2, a second main solvent and a second cosolvent; after mixing, performing second heating stirring; preparing an Sn precursor; heating the Sn precursor; after the temperature rises to 100 to 200 DEG C, adding the Cs precursor; performing stirring treatment; performing constant-temperature reaction for 10 to 20 min; preparing and obtaining the metal halide perovskite quantum dot CsSnX3, wherein in the CsX and the SnX2, the X is at least one of Cl, Br and I; the first cosolvent is diethyl allyl phosphate or N, N-dimethylformamide; the second cosolvent is diethyl allyl phosphate or N, N-dimethylformamide.

The invention relates to a novel graphene quantum dots (GQDs)-MnO2 composite catalyst and a preparation method thereof. MnO2 is combined with GQDs to prepare the GQDs-MnO2 composite catalyst for the first time by using the physical and chemical characteristics of MnO2 and GQDs. The GQDs-MnO2 composite catalyst is prepared by adopting a hydrothermal technology, and structure of the composite catalyst can be regulated through regulating the content of GQDs and MnO2 and the crystal form and the nanometer dimension of MnO2 in order to change the electrocatalytic performances. The preparation method concretely comprises the following steps: 1, preparing and processing MnO2; 2, carrying out hydrothermal compounding on GQDs and MnO2; and 3, post-processing. The preparation method of the GQDs-MnO2 composite catalyst has the advantages of simplicity, economy and good repeatability. The composite catalyst has high catalysis activity on an oxygen reduction reaction, has good stability, and is suitable for being used as a fuel cell cathode catalyst.

The invention belongs to the technical field of reusing of salt chemical wastes, and discloses a process for preparing high-strength gypsum from salt chemical wastes. The process for preparing the high-strength gypsum from salt chemical wastes comprises the following steps: step 1, mixing a calcium chloride solution with old brine and stirring to obtain mixed slurry of sodium chloride and dihydrate gypsum; step 2, desalting and washing the mixed slurry to obtain purified dihydrate gypsum slurry; step 3, regulating the dihydrate gypsum slurry to be acidic, adding an activity agent and a crystalmodifier, and preparing alpha-hemihydrate gypsum by a normal-pressure hydrothermal method; step 4, carrying out solid-liquid separation; step 5, carrying out desalting, acid removal and washing; andstep 6, drying to obtain the high-strength gypsum finished product. The process for preparing the high-strength gypsum from the salt chemical wastes has the beneficial effects that active growth of the intermediate dihydrate gypsum crystals is controlled effectively, and the strength of the high-strength gypsum is improved; the normal-pressure hydrothermal method is adopted, energy consumption islow, investments are low, and a crystal form is easy to control; and the problem of solid wastes is solved effectively, and the requirements of industrial and green sustainable development are met.

The invention discloses a high-quality high-purity semi-insulating silicon carbide single crystal, a substrate and a preparation method thereof and belongs to the field of semiconductor materials. Thepreparation method of the high-quality high-purity semi-insulating silicon carbide single crystal comprises the following steps: putting a silicon carbide raw material into a crucible, performing sublimation so as to obtain a sublimation raw material, and conveying the sublimation raw material into a primary seed crystal through an axial temperature gradient gas phase in the crucible to implementprimary crystal growth, so as to obtain the high-quality high-purity semi-insulating silicon carbide single crystal, wherein at least one transition seed crystal is arranged between the silicon carbide raw material and the primary seed crystal; and with the transition seed crystal, at least a part of the sublimation raw material has a single crystal growth-resublimation process once. By adoptingthe preparation method disclosed by the invention, the semi-insulating silicon carbide single crystal of a very high purity can be prepared from the silicon carbide raw material of a low purity, meanwhile, the growth quality of the high-purity semi-insulating silicon carbide single crystal can be also taken into account, and the production cost is low; and in addition, the high-purity semi-insulating silicon carbide single crystal and the substrate thereof disclosed by the invention are free of or slight in defect, high in purity, high in quality and good in uniformity.

The invention discloses a preparation method of titanium dioxide hollow nanospheres. The preparation method comprises the following steps: firstly, taking tetraethyl orthosilicate as a silicon sourceand preparing silicon dioxide microspheres by adopting a Stobe method; then cladding the surfaces of the silicon dioxide microspheres with a titanium dioxide precursor; then removing a silicon dioxideinner core by adopting strong alkali corrosion; finally, carrying out calcination and hydrothermal treatment to prepare anatase form titanium dioxide hollow nanospheres. The invention further discloses the titanium dioxide hollow nanospheres prepared by the preparation method provided by the invention. The method disclosed by the invention is simple to operate, low in production cost, small in process pollution, high in product yield, good in repeatability and suitable for large-scale production. A titanium dioxide nano-product prepared by the method has the advantages of high purity, good crystallization, controllable crystal form, fine particle granularity, uniform particles, good monodispersity, small particle size, large specific surface area and high photocatalytic activity.

The invention discloses a preparation method of titanium dioxide hollow nanospheres. The preparation method comprises the following steps: firstly, silicon dioxide microspheres are prepared from tetraethyl orthosilicate as a silicon source with a Stobe method, then, surfaces of the silicon dioxide microspheres are coated with a titanium dioxide precursor, silicon dioxide cores are removed by strong alkali corrosion, and finally, the crystalline titanium dioxide hollow nanospheres with flaky branch structures on the surface are prepared by hydrothermal treatment. The invention further disclosesthe titanium dioxide hollow nanosphere prepared with the preparation method. The method is simple to operate and good in repeatability, does not need high-temperature sintering, is suitable for large-scale production, avoids agglomeration of titanium dioxide powder, low in process pollution and achieves high product yield and low production cost; the obtained titanium dioxide hollow nanospheres have high purity, uniform particles, good crystallization, controllable crystal form, good dispersity, large specific surface area, high adsorption capacity and capture capacity for pollutants and highphotocatalytic efficiency, and a plurality of flaky branches are contained on the surface.

The invention discloses a method for preparing porous nano ferroferric oxide. The method comprises the steps: dissolving two of FeCl2.4H2O, FeSO4.7H2O, FeCl3.6H2O and Fe2(SO4)3 in one of polyvinyl alcohol, ethanol and deionized water or a mixture thereof to obtain a mixed solution containing Fe<2+> and Fe<3+>; adding one of NaHCO3, N2H4.H2O, Na2CO3, (NH4)2CO3 and NH4HCO3 in one of polyvinyl alcohol, ethanol and deionized water or the mixture thereof to obtain an alkaline substance aqueous solution; mixing the mixed solution containing Fe<2+> and Fe<3+> with the alkaline substance aqueous solution in a reaction vessel, heating, and stirring; adjusting the pH of the stirred mixed liquid to 8-13, keeping for 0.5-3 h, gradually adjusting the temperature to 30-60 DEG C, keeping the constant temperature for 2-24 h, allowing the mixed liquid to fully undergo a reaction, and after finishing the reaction, cooling to the room temperature; and washing the precipitate product after reaction with one of anhydrous ethanol and deionized water or a mixture thereof until the pH is 7, and drying for 8-36 h. The reaction process has no need of inert gas protection, and the industrialized production doorsill is low.

A spherical zirconium silicate nanometer crystal preparation method includes steps of adding ZrOCl2 8H2O, Na2SiO3 9H2O and PVP (polyvinyl pyrrolidone) into distilled water to obtain precursor liquid A, and adding LiF into the precursor liquid A to obtain liquor B; filling the liquor B in an ultrasonic generator to realize reaction under ultrasonic initiation, and naturally cooling to reach room temperature after reaction to obtain liquor C; pouring the liquor C into a hydrothermal reactor, then sealing the hydrothermal reactor, placing the hydrothermal reactor into a microwave hydrothermal reaction instrument, and naturally cooling to reach the room temperature after reaction to obtain liquor D; and collecting the liquor D by means of leaching of filter paper, then washing the collected liquor D by the aid of deionized water and anhydrous ethanol, and drying the washed liquor D in a draught drying cabinet to obtain spherical zirconium silicate nanometer crystals. Ultrasonic waves are adopted in a microwave hydrothermal method, so that the spherical zirconium silicate nanometer crystals with controllable crystalline forms and controllable sizes can be prepared at low temperature. Reactions are completed in liquid phase, accordingly, process equipment is simple, operation is convenient, raw materials can be obtained easily, preparation cost is low, distribution of grain sizes of the zirconium silicate crystals is narrow, the crystallize forms are controllable, reaction temperature is low, reaction period is short, and repeatability is good.

The present invention relates to betrixaban salts as shown by formula II, wherein the method for preparing these salts is simple, the crystal form is easy to control, the stability and solubility are good, and the salts are suitable for preparing a variety of preparations. The present invention also relates to the method for preparing these salts, pharmaceutical compositions comprising these salts, and the use of these salts in the preparation of medicaments for the prevention and treatment of diseases characterized by adverse thrombus formation in mammals.

The invention belongs to the field of iron phosphate preparation, and particularly relates to an iron phosphate continuous dehydration and crystal form controllable system and a control method thereof. The system comprises a flash steaming dryer, a cyclone dust collector, a rotary kiln, a second cyclone dust collector and a packaging machine, which are arranged in sequence along a logistical direction; a hot air blower which is used for supplying air to the flash steaming dryer is arranged at one side of the flash steaming dryer; the hot air blower is communicated with the bottom of the flashsteaming dryer; a beater which is used for beating the hot air and forming cyclone in the flash steaming dryer is arranged at the bottom of the flash steaming dryer; a second beater is arranged between the cyclone dust collector and the rotary kiln; the rotary kiln is an external electric heating type rotary calcining kiln; and a flash dry bag filter which is used for collecting free water tail gas not dehydrated by the cyclone dust collector is arranged between the flash steaming dryer and the rotary kiln. The iron phosphate continuous dehydration and crystal form controllable system and thecontrol method thereof are small in investment, low in energy consumption and suitable for large-scale popularization and application.

The invention discloses a method for preparing magnesium-aluminum-zinc hydrotalcite from aluminum-air battery electrolytic waste liquid, and application thereof. The preparation method comprises a scheme 1 or a scheme 2, and the scheme 1 comprises the following steps: filtering the aluminum-air battery electrolytic waste liquid in advance, reacting filtrate with a magnesium source and a zinc source, carrying out solid-liquid separation to obtain hydroxyl type magnesium-aluminum-zinc hydrotalcite, reacting the hydroxyl type magnesium-aluminum-zinc hydrotalcite with a carbon source, and filtering to obtain magnesium-aluminum-zinc hydrotalcite; and the scheme 2 comprises the following steps: directly reacting filtrate obtained by filtering the aluminum-air battery electrolytic waste liquid with the magnesium source, the zinc source and the carbon source, and performing solid-liquid separation to obtain magnesium-aluminum-zinc hydrotalcite. By adopting the method, resource utilization of the aluminum-air battery electrolytic waste liquid can be realized, the magnesium-aluminum-zinc hydrotalcite with a relatively high additional value can be obtained, the production cost of the hydrotalcite can be reduced, and the prepared magnesium-aluminum-zinc hydrotalcite is relatively low in impurity content, easy in crystal form control, simple in equipment operation, relatively low in production cost, energy-saving and environment-friendly, and is easy to realize industrial production.

The invention relates to an Au-TiO2 yolk-structured nanocomposite material and a preparation method thereof. The preparation method comprises the following steps: firstly preparing a gold nanosphere;then coating the surface of the gold nanosphere with a silicon dioxide layer; coating the surface of the silicon dioxide layer with a titanium dioxide precursor mesoporous material layer; then removing the silicon dioxide layer; and finally carrying out hydro-thermal treatment to obtain the Au-TiO2 yolk-structured nanocomposite material with a sheet-like branch structure on the surface. The preparation method of the invention is simple in process, easy to operate, low in production cost, small in process pollution and suitable for large-scale production; and the prepared Au-TiO2 yolk-structured nanocomposite material has a unique movable core and has the sheet-like branch structure on the surface, which can increase the specific surface area of the material, greatly enhance the photocatalytic performance of the material and realize high utilization rate of solar energy.