80 results about "Organophosphate" patented technology

The invention relates to the technical field of environmental monitoring, in particular to a method for determining two organophosphate compounds in water. The two organic phosphate ester compounds are tri-(2, 3-dibromopropyl)-phosphate ester and xylenol phosphate ester; the method comprises the following steps: 1, putting a water sample to be detected into a centrifugal tube, adding sodium chloride, uniformly mixing, adding acetonitrile as an extracting agent, uniformly mixing by vortex, standing for layering, and filtering supernatant liquid by a needle filter to obtain liquid to be detected; 2, mixing the prepared tri-(2, 3-dibromopropyl)-phosphate standard intermediate solution with the prepared xylenol phosphate standard intermediate solution, and diluting with acetone to obtain a standard working solution; the to-be-detected liquid obtained in the first step is placed in a liquid chromatography-triple quadrupole mass spectrometry combined system to be analyzed; the method provided by the invention can realize simultaneous determination of tri-(2, 3-dibromopropyl)-phosphate and xylenol phosphate, and fills the blank of combined detection of two specific organophosphate compounds in the prior art.

The utility model belongs to the technical field of organic pollutant removal, and provides a device for removing organophosphate in sewage by an iron-containing substrate reinforced artificial wetland, the iron-containing substrate comprises four layers, namely a gravel layer, a zeolite layer, a zeolite buffer layer and a quartz sand layer from bottom to top in sequence; and the zeolite layer is doped with an iron matrix. According to the device for removing the organophosphorus ester in the sewage by the iron-containing substrate reinforced artificial wetland, the reinforced removal of organophosphorus ester pollutants can be realized, the pollutant removal capability of an artificial wetland system is further effectively improved, and the ecological risk level of OPEs to a receiving water body is relieved; the device for removing the organophosphorus ester in the sewage by the iron-containing substrate reinforced constructed wetland is relatively simple in structure and convenient to construct, and has no other special requirements on the device in the process of removing the organophosphorus ester in the sewage, so that the operation cost can be effectively reduced.

The invention discloses a post-treatment liquid and application thereof in an anode foil formation post-treatment process, and the post-treatment liquid comprises the following components in percentage by mass: 0.1-5% of a main film-forming agent, 0.05-3% of a synergistic stabilizer and the balance of a solvent, the main film-forming agent is selected from at least one of a waterborne polyurethane emulsion and a silane coupling agent; the synergistic stabilizer is selected from at least one of organophosphate, molybdate and tungstate. The main film-forming agent and the synergistic stabilizer are compounded to obtain the post-treatment liquid, on one hand, the synergistic stabilizer is firmly combined with an aluminum oxide substrate to carry out deep passivation treatment on an oxidation film on the surface of the anode foil, and on the other hand, the synergistic stabilizer is subjected to network crosslinking with a hydrophobic protection layer formed by the main film-forming agent; the three-dimensional composite protective film can effectively isolate water molecules, repair microdefects on the surface of an oxidation film, prevent the phenomena of specific volume attenuation, leakage current increase and the like of the anode foil, and improve the long-term working reliability of the capacitor.

This invention provides a phosphorus-free, multifunctional, environmentally friendly scouring agent, its preparation method, and its application, belonging to the field of textile printing and dyeing technology. The surfactants used in this invention (including 2-ethylhexanol alkyl glycoside, 2-propylheptanol alkyl glycoside, 2-propylheptanol xyloside, and isomeric tridecyl alcohol ether carboxylic acid) are all nonionic surfactants. The resulting phosphorus-free, multifunctional, environmentally friendly scouring agent is easily soluble in water, acid-resistant, resistant to high-concentration strong alkalis, hard water-resistant, low-foaming, and has strong penetrating power. It is widely applicable to cotton and its blended textile processes, achieving excellent whiteness and wicking effect in conventional annealing / scouring / bleaching processes. It contains no alkylphenol polyoxyethylene ethers or organophosphates, causing no environmental pollution and simplifying and making textile pretreatment processes more environmentally friendly.

Textile fibers at least partially coated with a coating that includes particles of metal-organic frameworks dispersed in a polymeric base are provided. Also provided are fabrics formed from the textile fibers, protective gear and articles of clothing made from the fabrics, and methods of using the fibers and fabrics to catalyze the hydrolysis of organic molecules, such as organophosphate-based nerve agents, having hydrolysable bonds.

The application discloses a limiting distribution model for predicting accumulation of organic phosphates (OPEs) in rice grains and a construction method thereof, and belongs to the technical field of environmental pollutant migration prediction and agricultural safety. The model is based on the limiting distribution theory, systematically identifies four key links (soil-root absorption, root-stalk transportation, stalk-leaf distribution and leaf-grain migration) of OPEs migration from soil to rice grains and limiting factors of each link, realizes accurate prediction of grain accumulation under different OPEs, different environmental conditions and different rice varieties by quantifying and integrating distribution coefficients of each link. The application calibrates distribution coefficient equations of each link by measuring physical and chemical parameters of OPEs, soil environmental parameters, rice physiological parameters and in-vivo distribution data, the relative error of model prediction is less than or equal to 15%, the model can be applied to farmland OPEs pollution risk assessment, optimization of prevention and control measures and food safety early warning, and has the advantages of strong universality, simple operation and accurate prediction.

The present invention relates to a gel-type polymer electrolyte, a lithium metal battery comprising same, and a method for manufacturing same and, more specifically, comprises: an organic solvent; a lithium salt; an additive; and a crosslinked polymer, wherein a current collector includes an organic phosphate, the lithium salt includes at least one of a borate-based lithium salt and a fluorine-based lithium salt, and the organic phosphate is a low-molecular compound having a molecular weight (Mw) of 100-400 g / mol and is dispersed in the organic solvent.

The invention relates to the technical field of lithium batteries, in particular to a modified lithium iron phosphate positive active material, a preparation method thereof and a lithium battery. The modified lithium iron phosphate positive electrode active material comprises a main crystal phase, a conductive second phase dispersed and distributed at the crystal boundary of the main crystal phase, and a carbon coating layer located on the outer surface and coating the main crystal phase and the conductive second phase; the main crystalline phase material is lithium iron phosphate with an olivine structure; the conductive second phase material is lithium vanadium phosphate; the lithium battery disclosed by the invention adopts a modified lithium iron phosphate positive electrode active material which takes LiFeP as a main crystal phase, coexists with an L (P) conductive second phase and is externally coated with a low-content thin carbon layer, and is matched with a high-temperature stable electrolyte containing lithium difluorophosphate and / or lithium difluoro (oxalato) borate, lithium hexafluorophosphate and organophosphate; the problem of considering high rate and high-temperature storage safety of the lithium battery is solved synergistically from two aspects of a material phase structure and an electrolyte.

The invention belongs to the technical field of compound screening, and provides a method for rapidly screening mass spectrum positive signals of organophosphorus ester compounds, which comprises the following steps of: performing binary coding on OPEs compounds and non-OPEs compounds to establish a mass spectrum database, training a machine learning model by using a data set in the mass spectrum database, and screening the mass spectrum positive signals of the organophosphorus ester compounds to obtain the mass spectrum positive signals of the organophosphorus ester compounds. And after training is completed, the machine learning model is used for predicting a mass spectrum to be detected, and screening of the organophosphate compounds is completed. According to the method, manual mass spectrum comparison is not needed, the screening flux is improved, a foundation is laid for standardized application of the screening process, and the screening efficiency is improved; in the screening process of an actual sample, the screening efficiency is improved from the original hour level to the minute level, and the purpose of rapidly screening the organophosphate compounds is achieved.

The application provides a needle flame resistant flame-retardant polycarbonate composition and a preparation method thereof, and relates to the technical field of flame-retardant polycarbonate materials.The needle flame resistant flame-retardant polycarbonate composition contains, in terms of weight parts, 100 parts of polycarbonate and 1-15 parts of a hyperbranched flame retardant; the hyperbranched flame retardant is obtained by reacting raw materials containing double-end hydroxyl polysiloxane and phosphorus oxychloride. The application adds the hyperbranched flame retardant to the polycarbonate, combines the characteristics of polysiloxane and organic phosphate, has good flame-retardant performance, and achieves needle flame resistance, flame retardation and UL-94 vertical combustion V-0 grade.

A pretreatment method suitable for perfluorinated and polyfluoroalkyl compounds and organophosphorus esters in a biological sample comprises the following steps: adding acetonitrile into the biological sample, adding an internal standard, carrying out vortex, centrifuging, extracting a supernatant, adding acetonitrile again, carrying out vortex, centrifuging, extracting a supernatant again, combining the two supernatants, and carrying out freeze-drying to obtain the perfluorinated and polyfluoroalkyl compounds and organophosphorus esters. And carrying out solid-phase extraction, nitrogen concentration, methanol redissolution and sample introduction analysis on the merged supernate by adopting a phospholipid small column. According to the pretreatment method, firstly, acetonitrile is used for removing protein in a biological sample, then a phospholipid removal small column is used for further purifying fat substances in a solution, it is ensured that a target analyte is not interfered, nitrogen concentration and methanol redissolution are conducted, the purity and detection sensitivity of the sample are improved, the recovery rate of PFASs and OPEs reaches the ideal range, and the method is suitable for industrial production. And reliability and effectiveness are realized.

The invention provides a surface water organophosphate pollution ecological risk prediction method and system, and the method comprises the steps: obtaining an observation sample organophosphate concentration data set and social economic and environmental variable data, and carrying out the preprocessing; the method comprises the following steps: screening social economic and environmental variables through an MC-UVE-RF method, and reserving variables having significant influence on concentration as a model to construct a data set; constructing a random forest quantitative model by using the model construction data set and the observation sample concentration, optimizing parameters and judging whether the model prediction is accurate or not; utilizing the model of the target area to construct a variable data set and a convergent concentration quantitative model to predict the organophosphate concentration of the target area; and quantifying the ecological risk by using the organic phosphate concentration predicted value, identifying the ecological risk level, and projecting the ecological risk level to the target region. According to the method, the accuracy of predicting the concentration of the organophosphorus ester in the surface water is improved, and reliable evaluation on the ecological risk of the organophosphorus ester is realized.

A battery cell is presented. The battery cell has a negative electrode, a positive electrode, and a separator positioned between the electrodes. The separator includes a water wicking thermo-responsive organophosphate ceramic coating configured to release water as a temperature within the battery cell rises.

A process for producing three recombinant enzymes capable of hydrolyzing each class of organophosphate, carbamate, and pyrethroid insecticides, as well as a formulation containing these enzymes provides the recombinant plasmid DNA vector, in which the protein secretory system has been modified to enhance the secretion of recombinant protein into the periplasmic space or culture medium. A nucleotide sequence encoding PelB (pectate lyase B) signal sequence for periplasmic localization is deleted and replaced with a nucleotide sequence encoding LamB (maltoporin or phage lambda receptor) signal sequence to enable a more efficient secretory recombinant protein. Three recombinant plasmid DNA vectors for the expression of recombinant proteins that are constructed using the modified plasmid DNA vector described above. The recombinant proteins include a recombinant organophosphate-hydrolyzing enzyme; a recombinant carbamate-hydrolyzing enzyme; and a recombinant pyrethroid-hydrolyzing enzyme.

This invention discloses an α-indolylpyrrolo[1,2-a]indole derivative and its preparation method. The derivative is a levorotatory or dextrorotatory optically active form or racemate with the following structural formula: The preparation involves using α-indolylpropynyl alcohols and indole compounds as raw materials, and 3,5-bis(trifluoromethyl)phenylbinaphthylphosphonic acid as a catalyst, reacting in an organic solvent to obtain the α-indolylpyrrolo[1,2-a]indole derivative. This invention utilizes an organophosphate-catalyzed tandem reaction of two components to synthesize the α-indolylpyrrolo[1,2-a]indole derivative. The reaction conditions are mild, the process is simple, and the operation is convenient. The obtained product is the core skeleton of the indole bases of the natural products isoborreverine and dimethyl isoborreverine, which is of great significance for the synthesis of analogs of these natural products.

The invention discloses a lithium metal battery monomer and a preparation method thereof, a battery device and a power utilization device, and the preparation method of the lithium metal battery monomer comprises the following steps: assembling a positive pole piece, a negative pole piece, an isolating membrane and an electrolyte to obtain a primary lithium metal battery monomer, the negative pole piece comprises a negative current collector and a lithium-based metal layer located on the negative current collector, the electrolyte comprises an ester additive, and the ester additive comprises at least one of organophosphate, organic borate, organic sulfate, organic sulfite and organic sulfonate; at a first temperature, discharging the primary lithium metal battery monomer to a first voltage at a first rate current, standing for a first time, then discharging the primary lithium metal battery monomer to a second voltage at a second rate current, the first rate current being greater than or equal to 1C, the second rate current being less than 1C, and the first voltage being greater than the second voltage, the first voltage is smaller than the lower limit cutoff voltage of the lithium metal battery monomer; and after standing for a second time, repeating the discharging process to obtain the lithium metal battery monomer. The lithium metal battery monomer has low gas production rate and long cycle life in a high-temperature environment.

The invention relates to the technical field of phytoremediation of soil polluted by organophosphate flame retardants / plasticizers, in particular to a method for remedying soil polluted by chlorinated organophosphate by using compositae plant jerusalem artichoke. The compositae plant jerusalem artichoke is planted in the soil polluted by the chlorinated organophosphate, and the plant degrades, removes or remarkably reduces the content of phosphate tri (2-chloroethyl) ester, phosphate tri (1-chloro-2-propyl) ester and phosphate tri (1, 1-dichloro-2-propyl) ester in the soil through the synergistic effect of absorption and root system secreted substances in the growth process. And the content of chlorinated organophosphorus esters such as 2, 3-dichloro-2-propyl) ester and the like is increased. According to the method, the energy plant jerusalem artichoke capable of being used for producing bioethanol or methane is adopted for repairing the soil polluted by the chlorinated organophosphate, the method has the advantages of being small in investment, not high in technical requirement, capable of being used for in-situ repairing and the like, and the situation that the chlorinated organophosphate in the soil enters a food chain through plants and then harms human health can be avoided; meanwhile, raw materials can be provided for production of biological energy.

The invention provides a wide-band-gap perovskite solar cell and a preparation method and application thereof. The wide-band-gap perovskite solar cell comprises a conductive substrate, a hole transport layer, a perovskite active layer, an electron transport layer and an electrode layer which are sequentially stacked. The perovskite active layer comprises an organic phosphate ester compound. According to the wide-band-gap perovskite solar cell, the organophosphate compound is introduced into the perovskite layer, Br / I competitive crystallization and component distribution are regulated and controlled, phase homogenization of wide-band-gap perovskite is achieved, the ion migration potential barrier is improved, non-radiative recombination, component degradation and crystalline phase segregation are restrained, and the performance of the solar cell is improved. Therefore, the photoelectric properties and stability of the wide-band-gap perovskite solar cell and the perovskite-organic laminated solar cell are improved, and the problems of non-uniform phase distribution, high defect density, poor stability and the like caused by ion mismatching and crystallization kinetics problems of wide-band-gap perovskite are solved.

The purpose of the present invention is to provide a treatment agent for recycled cellulose fiber excellent in nep preventing properties.　This treatment agent for recycled cellulose fiber contains (A) an organic phosphate ester compound having a hydrocarbon group with 14-22 carbon atoms including a compound (A1) represented by general formula (1) and a compound (A2) represented by general formula (2); and (B) a nonionic surfactant. The weight ratio (A / B) of the compound (A) to the surfactant (B) is 0.05-1.0. In formula (1), R1 is a monovalent saturated hydrocarbon group with 14-22 carbon atoms. M1 and M2 are each independently a hydrogen atom, an alkali metal, ammonium, phosphonium, an organic amine or a quaternary ammonium. In formula (2), R2 and R3 are each independently a monovalent saturated hydrocarbon group with 14-22 carbon atoms. M1 is a hydrogen atom, an alkali metal, ammonium, phosphonium, an organic amine or a quaternary ammonium.

This invention discloses a comprehensive recovery method for nickel, cobalt, manganese, and scandium, belonging to the field of metal production or refining technology. The method includes: pretreatment of nickel-cobalt hydroxide by ultrasonic grinding with oxygen / air introduction; selective leaching of the pretreated nickel-cobalt hydroxide with dilute sulfuric acid solution, followed by solid-liquid separation to obtain manganese oxide slag and a first leachate; using a synergistic extraction system formed by a compound of an organophosphate extractant, a neutral phosphorus-oxygen extractant, and an organic diluent as the first extractant; scandium extraction of the first leachate using the first extractant to obtain a scandium-loaded organic phase and raffinate; precipitation of vanadium and removal of iron in the raffinate, followed by solid-liquid separation to obtain iron alum slag and a second leachate; and nickel-cobalt extraction of the second leachate to obtain a nickel-cobalt-loaded organic phase. This invention enables efficient recovery of nickel, cobalt, manganese, and scandium, and effective separation from impurities.

This invention relates to the field of butadiene polymerization technology, and particularly to a butadiene polymerization catalytic system, preparation method, and butadiene polymerization method. The butadiene polymerization catalytic system includes component A, component B, component C, and component D. Component B is an alkylaluminum compound, component C is a boron trifluoride complex, and component D is a homogenizing agent. Component A consists of two parts: component A1 and component A2, wherein component A1 is nickel organophosphate, and component A2 is alkyl nickel acid with a cyclic structure. The preparation process of the catalyst of this invention is simpler, and the product has higher purity, a more defined composition, and a wider and more abundant supply of raw materials, thereby achieving the goals of reducing costs and stabilizing the production process and product quality. Using the technical solution provided by this invention for the production of nickel-based cis-butadiene rubber results in a high polymerization conversion rate of butadiene monomer, good physical and mechanical properties of the product, and low gel content.

The invention belongs to the crossing field of metal organic framework crystalline materials and chemical protection, and discloses a metal organic framework crystalline material containing an N-ethyl morpholine buffer system and a preparation method and application thereof. A carboxylic acid ligand containing an N-(2-aminoethyl) morpholine group and metal ions M < 4 + > ions (M = Zr, Hf, Ce and the like) or MO < 2 + > ions or metal clusters M6 (mu3-O) 4 (mu3-OH) 4 are assembled to prepare the crystalline porous metal organic framework material containing an N-ethylmorpholine (NEM) buffer system and having a specific topological structure (fcu, spn, csq, kgd and the like), and the crystalline porous metal organic framework material is called MOFs-NEM for short. The main representative materials comprise M-MOF-808-xNEM (M = Zr, Hf, Ce) (x = 1, 2, 3), M-UiO-66-NEM, M-UiO-67-NEM, M-UiO-68-xNEM (x = 1 and 2), M-BTB-xNEM (x = 1, 2 and 3), M-NU-1000-4NEM and the like. The MOFs-NEM meets the requirements of catalytic hydrolysis of organophosphorus ester on a high-accessibility catalytic active center and a buffer system, and realizes efficient catalytic hydrolysis of the organophosphorus ester nerve poison in a humidity environment.

The objective of this invention is to provide a treatment agent for polyester synthetic fibers, which improves the emulsion stability when the treatment agent is prepared as an aqueous dilution, reduces the adhesion of the fiber surface to which the treatment agent has been applied, and suppresses the reduction in fiber strength. The polyester synthetic fiber treatment agent of this invention contains at least 5% by mass of a (poly)oxyalkylene derivative (A), at least 1% by mass of an inorganic acid compound (B), and at least 5% by mass of an organophosphate compound (C). The 1% by mass aqueous dilution of the polyester synthetic fiber treatment agent has a pH of 5.5 or higher and 8.5 or lower at 25°C. The inorganic acid compound (B) is selected from at least one of sulfuric acid, nitric acid, hydrochloric acid, and their salts. The organophosphate compound (C) is selected from at least one of an organophosphate having an alkyl group having 16 or more and 20 or fewer carbon atoms, and their salts.

This invention discloses a compound modified masterbatch for improving the heat-sealing strength of PLA tea bags and its preparation method, belonging to the field of polymer materials technology. By weight, it comprises the following components: 35-50 parts polylactic acid carrier; 18-28 parts toughening agent; 3-8 parts composite nucleating agent; 1-4 parts crystallization promoter; 2-5 parts interface compatibilizer; and 0.5-2 parts antioxidant. The toughening agent is a blend of polybutylene adipate-terephthalate and polybutylene succinate in a mass ratio of (1.5-2.5):1. The composite nucleating agent is composed of an organophosphate nucleating agent and an acylhydrazine compound in a mass ratio of 1:(0.8-1.5). This invention systematically improves the heat-sealing strength of PLA tea bags from three dimensions—toughening, nucleation, and promotion—from the perspectives of interfacial adhesion, crystal structure, and molecular motion, overcoming the limitations of single modification methods.

The invention relates to the technical field of concrete, and particularly discloses a modified steel slag mixture and a preparation method and application thereof, the modified steel slag mixture comprises modified steel slag, Portland cement, fly ash, silica fume, activated coal gangue and emulsified asphalt; the modified steel slag is prepared from the following raw materials: steel slag, phosphate modified graphene oxide, a polycarboxylate superplasticizer, water glass and sodium sulfate; the phosphate-modified graphene oxide is prepared from the following raw materials: organophosphate and graphene oxide. According to the invention, the P-GO is anchored on the surface of the steel slag, so that agglomeration of a nano material in a cement matrix is avoided. The anchored P-GO captures Fe < 3 + > dissolved out of the C2F in situ, and drives the C2F to be continuously dissolved; the dissolved Fe < 3 + > and Ca < 2 + > are quickly consumed by the water glass and the sodium sulfate, C-(F)-S-H gel and ettringite are generated, circulation is formed, and the problems of insufficient early strength and poor volume stability of the steel slag are synchronously solved.

The present technology generally relates to methods of treating social deficits with HDAC inhibitors. Select embodiments of the present technology include a method for treating organophosphate induced social deficits in a subject, comprising administering to a subject in need thereof a therapeutically effective amount of an HDAC inhibitor selected from the group consisting of valproic acid, butyric acid, BRD-6929, RGFP966, pharmaceutically acceptable salts thereof, and combinations thereof. The subject may have been diagnosed with a disease or disorder characterized by social deficits, such as autism spectrum disorder. The subject may be monitored for a change in the severity of social deficits.

The invention discloses a flame-retardant, high-pressure-resistant and long-cycle-life PVDF (polyvinylidene fluoride)-based polymer solid electrolyte, and belongs to the technical field of lithium ion battery solid electrolytes. The PVDF-based polymer solid electrolyte is composed of a polymer, a lithium salt, an organophosphate solvent and a nitrogen and boron salt-containing additive. The polymer is PVDF (Polyvinylidene Fluoride); the lithium salt is selected from one or two of LITFSI and LIFSI; the organophosphate solvent is one or two of TMP (Trimethoprim) and TEP (Tetraethyl Pyrrolidone); the salt-type additive comprises a nitrogen salt-containing additive and a boron salt-containing additive, the nitrogen salt-containing additive is LINO3, and the boron salt-containing additive is one or more of LIDFOB, LIBOB and LIBF4. According to the method designed in the invention, the physical and chemical properties of the PVDF-based polymer solid electrolyte are changed, the PVDF-based polymer solid electrolyte has a flame-retardant effect due to the organic phosphate solvent, an electrochemical window is improved to 4.98 V, the nitrogen-containing boron salt type additive generates uniform SEI / CEI rich in boron and nitrogen on the surface of an electrode material, the interface stability can be maintained, and the cycle performance of a battery is improved.

This invention discloses a biocontrol and growth-promoting bacterium for garlic leaf blight. Bacillus sp.NWAFU 59-20 and its applications belong to the field of microbial biocontrol agents technology. Bacillus sp. NWAFU 59-20 was deposited on January 23, 2026, at the China Center for Type Culture Collection (CCTCC), Wuhan University, Wuhan, China, with accession number CCTCC NO: M 2026210. It possesses nitrogen-fixing, potassium-solubilizing, organophosphate-solubilizing, protease-producing, and cellulase-producing functions. Experiments on garlic seedling resistance to leaf blight and on the growth-promoting effects of garlic, cucumber, and tomato seedlings showed that this biocontrol strain significantly promoted the growth and development of garlic, cucumber, and tomato seedlings, significantly alleviated symptoms of garlic leaf blight, and exhibited good broad-spectrum resistance to plant diseases. This provides a valuable reference for the breeding of strains suitable for resistance to garlic leaf blight and for promoting growth.

The present disclosure provides "battery flame retardants". A battery cell is presented. The battery cell has: a negative electrode; a positive electrode; and a separator plate positioned between the electrodes. The separator includes a water core endothermic response organophosphate ceramic coating configured to release water as the temperature within the battery cell increases.

The invention belongs to the field of chemical ecology of agricultural pests and pesticide science, and relates to an insecticide composition for improving the sensitivity of agricultural pests to insecticides and application of the insecticide composition. Folic acid is applied to a pest feeding substrate, a host plant or a feed, so that the sensitivity of pests to various insecticides (including neonicotinoids, pyrimidines, pyrethroids, organophosphorus and the like) can be remarkably enhanced. It is found that folic acid can regulate and control a carbon metabolism network in pests and inhibit cytochrome P450 and other detoxification enzyme related pathways, and then the endurance capacity of the pests to insecticides is reduced. The composition and the method are verified in seven important pests such as brown planthopper, sogatella furcifera, spodoptera frugiperda, cotton aphid, chilo suppressalis, panonychus citri and thrips, have the advantages of improving the pesticide effect, reducing the pesticide application amount and delaying the resistance evolution, and can be widely applied to comprehensive treatment of agricultural pests.