183results about How to "No skin irritation" patented technology

Disclosed herein are a highly purified tocopheryl phosphate and / or a salt thereof (tocopheryl phosphates) wherein a P,P'-bistocopheryl hypophosphate and / or a salt thereof (P,P'-bistocopheryl diphoshates) is contained in a proportion of not higher than 3% by weight; a process for producing a highly purified tocopheryl phosphate and / or a salt thereof, which comprises the steps of reacting a tocopherol with an oxyphosphorus trihalide followed by treating with an acid or basic aqueous solution to thereby form tocopheryl phosphates (i) in which P,P'-bistocopheryl diphoshates (ii) formed as by-products are contained, hydrolyzing the P,P'-bistocopheryl diphoshates (ii) under acid condition, and, optionally, rendering the hydrolyzate neutral or basic under basic condition; and a method of analyzing tocopheryl phosphates, comprising analyzing a sample containing components (i) and (ii) with the use of a high-performance liquid chromatograph column packed with a gel of a polymethacrylate having, bonded thereto, long-chain alkyl groups. None or only an extremely minute amount of P,P'-bistocopheryl diphoshates are contained in the highly purified tocopheryl phosphates, so that the highly purified tocopheryl phosphates exhibit antioxidant and blood circulation promoting effects, have excellent water solubility, are powdery so that the handling thereof is extremely easy, are free from cutaneous irritation and allergenecity and ensure dermal safety. Therefore, the highly purified tocopheryl phosphates are useful as cosmetic ingredients. The amounts of components (i) and (ii) can be simply measured with high accuracy by the above method.

An adjustable face mask having a body conforming substantially to the facial structure of a wearer. The face mask is provided with a neck shield and removable filter and novel air apertures providing a communication of forced air to the nose and mouth of a user. The face mask can optionally provide neck protection with a descending neck member.

Composition for removal of nail polish, plaster, adhesives, discolorations or other adhesive products on the skin and / or nails, which to at least 20% includes one or more esters of one or more natural oils, which further includes one or more synthetic esters, and which is substantially free from volatile solvents. The invention also refers to a composition of the same type for paintbrush wash and / or removal of industrial paint or other adhesive products on objects.

An improved composition for skin cleansing and protection is disclosed. The composition contains an effective amount of at least one alpha-hydroxyl acid or a pharmaceutically acceptable salt thereof, at least one base, one surfactant and one skin protectant. Various additives and excipients may be included in the formulation. The improved composition disclosed herein achieves a higher bacteria killing rate and shows longer action duration. The disclosed composition is capable of penetrating deep into the skin which allows for delivery of more anti-microbials to sites that are at a higher risk of being infected. Various modifications of the improved composition are also disclosed.

The invention discloses a method for preparing a porous polymer micro needle by using a template method and an application thereof. The method comprises the following steps of: (1) dissolving a polymer and a template agent in a solvent to prepare a polymer solution; (2) filling the polymer solution into a micro needle mould; (3) removing the solvent in the obtained micro needle mould to obtain a solid micro needle; (4) removing the template agent in the obtained solid micro needle to obtain the porous polymer micro needle. By improving the overall process flow design of the preparation method,the method can solve the technical problems of a complex preparation process, harsh conditions, a complicated process, high price, difficult control of the pore structure and size, difficult large-scale production and application and the like of the porous polymer micro needle, the obtained porous polymer micro needle can be used for tissue fluid extraction and transdermal administration, such asskin tissue fluid and blood extraction and transdermal administration of proteins, polypeptides and small molecular drugs in cosmetic, hair growth, immunity, treatment and other applications.

The invention relates to a dispersing dye mixture and the dye products that has no thrill to skin and has good application capability. The feature is that the mixture at least contains a kind of dye compounding of formula (I) and a kind of dye compounding of formula (II).

The invention belongs to the technical field of cosmetics, and relates to a skin care product with sunscreen and sun repair functions and a preparation method thereof. The skin care product with the sunscreen and sun repair functions comprises the following components: sodium copper chlorophyllin, cytokine complex liposome, an asparagus extract, a flos lonicerae extract, an ash bark extract, dipotassium glycyrrhizinate, shea butter, butanediol, beta-glucan, sodium hyaluronate, xanthan gum, trehalose, hydrogenated jojoba oil, squalane, cyclopentasiloxane, cetearyl glucoside, cetearyl alcohol, PEG-100 stearate, tocopheryl acetate, bisabolol, a preservative, essence and deionized water. The skin care product with the sunscreen and sun repair functions, provided by the invention, is reasonable in formula, stable in property, mild in effect and free from skin irritation and has the obvious sunscreen and sun repair functions under the synergistic action of the various effective components.

Provided is a skin external composition, which includes tranexamic acid or a salt thereof and a skin penetration enhancer, thereby showing remarkably increased skin permeability and improved sense of use, skin irritation, and storage stability.

The invention belongs to the technical field of medical dressing, and discloses a carbon quantum dot / nano-silver alginate dressing and a preparation method and application thereof. A carbon quantum dot / nano-silver composite material is prepared from silver nitrate, polyethylene glycol 400, sodium citrate, ascorbic acid and carbon quantum dots; and the carbon quantum dot / nano-silver composite material is added to a sodium alginate solution to prepare the carbon quantum dot / nano-silver alginate dressing through an electrostatic spinning technology and a non-woven technology. According to the dressing prepared by the technology, the mechanical property of the alginate dressing can be significantly improved; meanwhile, the dressing has an excellent fluorescent display tracking function; the migration change and the accumulation condition of silver ions in a body can be effectively inspected; and a fast and effective detection method is provided for clinical supervision of the silver ions.

A dry shaver has an elongated shaving head with a lengthwise axis. The shaving head carries semi-cylindrical first and second outer cutters disposed on its opposite width ends, and a semi-cylindrical finishing cutter and a slit cutter interposed between the first and second outer cutters. The finishing cutter has a finishing foil which is deeply curved than a foil of the first and second outer cutters into an arcuate contour having a width less than that of the first and second outer cutters. The finishing foil disposed behind the first outer cutter comes into contact with a user's skin to make closer shaving than the first and second cutters. A skin guard project between the first outer cutter and the finishing cutter to protect the skin from being pressed excessively to a side of the finishing foil when moving the shaving head across a user' skin with the first outer cutter leading in a moving direction, thereby reducing skin irritation.

The invention provides a topical formulation adapted for treatment of a skin condition comprising (i) at least one retinoid; and (ii) salicylic acid or an ester, amide, salt, or solvate thereof. The invention also includes a kit for treatment of skin conditions comprising a retinoid and salicylic acid, as well as a method of treating skin conditions utilizing the inventive formulation and kit.

A topical applications is used to treat and prevent the spread of nail infections or onychomycosis caused by bacteria, fungi and other pathogens. The topical application has a composition that comprises, as an active ingredient, at least one species selected from the group consisting of 2,2′-(alkyldioxy)bis-(alkyl-1,3,2-dioxaborinane) and 2,2′-oxybis(alkyl-1,3,2-dioxaborinane). More specifically, the composition comprises, as an active ingredient, at least one member selected from the group consisting of 2,2′-(1-methyltrimethylenedioxy)bis-(4-methyl-1,3,2-dioxaborinane) and 2,2′-oxybis(4,4,6-trimethyl-1,3,2-dioxaborinane).

The invention belongs to the field of medical dressings, and particularly relates to a bamboo alginate functional dressing and a preparation method thereof. The dressing comprises the following components in parts by weight: 1-4.2 parts of sodium alginate, 0.05-0.4 part of sodium hyaluronate, 0.25-2 parts of collagen, 4.5-31 parts of bioactive glass powder and 62-95 parts of bamboo fiber. The dressing can quickly promote healing of a wound surface, and healed wound surface is smooth and resilient and is less prone to scar proliferation; and the dressing has the functional characteristics of antisepsis, imbibition, hemostasis, adhesion prevention, no cytotoxicity and the like, and can satisfy various requirements for wound surface healing. According to the preparation method of the bamboo alginate functional dressing, the problem that the alginate medical dressing is cracked after exudate imbibition is solved, thereby facilitating dressing change by medical personnel.

The present invention provides hydroxamic acid derivatives represented by the following formula (I), having anti-aging efficacy and a method for preparation thereof: wherein, R1 is herein, R5 and R6 each independently represents a hydrogen atom, a C1-C10 alkyl group or a C3-C6 cyclic alkyl group; R2 is CONH, NHCO, CONR7 or NR7CO, herein, R7 represents a C1-C10 alkyl group; R3 is —(CH)n—, herein, n=0 or 1; and R4 is a hydrogen atom or a C1-C10 alkyl group. Further, the present invention provides skin-care external compositions for preventing skin aging, containing said hydroxamic acid derivatives represented by the formula (I) as an active ingredient.

A dermal topical formulation containing p-menthane-3,8-diol and a whitening component such as arbutin, kojic acid, ellagic acid, ascorbic acid or its derivative, lactic acid, glycolic acid, tartaric acid, and an essence or an absolute extracted from a plant such as labdanum, jasmine and mugwort (T.vulgare). The dermal topical formulation is highly safe and capable of promoting the percutaneous absorption of the whitening component.

The present invention provides hydroxamic acid derivatives which have anti-aging efficacy and a method for preparation thereof. It is further provided skin-care external compositions for preventing skin aging, containing the hydroxamic acid derivatives represented by the formula (I) as an active ingredient.

A yoga garment wrap, one each for the hand and the foot, each including opposite, external-surface-contact, and external-surface-non-contact side structures extending between open front and rear ends, and elastomeric, inter-digit, motion-and-escape-restraining straps, or a single strap, spanning the wrap's open front end, and interconnecting, the wrap's two side structures. The contact side structure includes an outer high-frictioning expanse, and a surface-to-surface loosely adjacent, inner moisture-wicking liner. Non-internally welted, or otherwise internally projecting seam structure units the lateral edges of the wrap's side structures.

The invention discloses an andrographis paniculata hand sanitizer and a preparation method thereof. The andrographis paniculata hand sanitizer has a formula comprising the following raw materials in parts by weight: 0.3 to 3 parts of andrographis paniculata extract, 20 to 50 parts of surface, 1 to 10 parts of propylene glycol, 8 to 15 parts of glycerinum, 1 to 5 parts of essence, 2 to 5 parts of sodium chloride, and 40 to 60 parts of water. According to the andrographis paniculata hand sanitizer, propylene glycol and glycerinum are used together in a certain proportion in the formula, so that the andrographis paniculata extract in the formula can be dissolved fully, and the stability of the hand sanitizer can be kept at a low temperature. The result of an in-vitro drug sensitive test shows that the andrographis paniculata hand sanitizer has a good antibacterial effect.

A patient bed is provided for transporting and / or positioning a patient. The patient bed has a bed area provided for receiving a patient. The patient bed is flexible at least in the bed area in such a way that the patient bed can be rolled up around a part of the patient bed. The patient bed has at least one transport mount for acting on by a transporter, and the patient bed is designed to be transported via the at least one transport mount when loaded with a patient. The patient bed has a plurality of reinforcing fibers, which are flexible and tension-proof, wherein each of the reinforcing fibers passes through the bed area and is operatively connected to at least one of the at least one transport mount in such a way that a force acting on the bed area can be transmitted at least partially to the at least one transport mount.

A yoga garment wrap, one each for the hand and the foot, each including opposite, external-surface-contact, and external-surface-non-contact side structures extending between open front and rear ends, and elastomeric, inter-digit, motion-and-escape-restraining straps, or a single strap, spanning the wrap's open front end, and interconnecting, the wrap's two side structures. The contact side structure includes an outer high-frictioning expanse, and a surface-to-surface loosely adjacent, inner moisture-wicking liner. Non-internally welted, or otherwise internally projecting seam structure units the lateral edges of the wrap's side structures.

A Chinese medicine for treating trichomonas vaginitis, non-specific vaginitis, pudendal itching, etc is prepared from 7 Chinese-medicinal materials including earthworm, flavescent sophora root, cnidum fruit, cloves, etc. Its preparing process and its quality control method are also disclosed.

The invention discloses a production method and application of a porous polymer microneedle. The production method includes the steps of firstly, dissolving polymer into a solvent to obtain a polymersolution; secondly, filling the polymer solution into a microneedle mould; thirdly, freezing the whole microneedle mould filled with the polymer solution; fourthly, using freeze drying treatment to remove the solvent contained in the frozen microneedle to obtain the porous polymer microneedle, wherein the freeze drying treatment is performed under the pressure intensity of 0-100Pa. The productionmethod has the advantages that large-scale porous polymer microneedle production can be achieved by the simple and mild freeze drying technology, the technical problems that the production process ofthe porous polymer microneedle is complex, harsh in conditions, expensive, hard in pore structure, size and distribution control and difficult in large-scale production and application and the like can be solved; the produced porous polymer microneedle is applicable to tissue fluid extraction and transdermal drug delivery.

A gel of paeonal as an improvement on paeonal ointment is prepared from paeonal, clove oil, tween-80, carbomer and sodium pyrosulfite. Its advantages are less volatilization of paeonal, high filming performance, slow release and high curative effect. Its preparing process and quality control method are also disclosed.

The invention discloses a nano-encapsulated retinol anti-acne gel and a production method thereof. The nano-encapsulated retinol anti-acne gel comprises, by weight, 0.5-5 parts of retinal, 1-3 parts of vitamin C, 1-20 parts of phospholipid, 20-40 parts of polyethylene glycol-20, 10-20 parts of caprylic triglyceride or capric triglyceride, 10-30 parts of glycerol and 5-10 parts of water. The production method of the nano-encapsulated retinol anti-acne gel is simple, and raw materials in the invention accord with cosmetic healthiness standards; and the nano-encapsulated retinol anti-acne gel has an obvious treatment effect on acnes in various stages, and is basically suitable for all people.

The invention provides a knitting method of a multi-bar warp-knitting machine. The method includes the following steps of firstly, preparing a raw material wire; secondly, feeding the raw material wire into a looping ground bar; thirdly, making the looping ground bar start knitting, wherein the raw material wire is composed of N yarns, N is larger than or equal to 1, and at least one of the N yarns is a raveling-resistant yarn. Raveling-resistant yarn loops are added on the basis of existing loops, the tightness of the existing loops is increased, joints of all the loops are staggered or overlapped, ground net yarn loops are made to have quite strong cohesive force and more closely cohered to fancy yarns forming a pattern, and even no chain stitch transfer transverse yarn or thermofuse yarn is added, the ground yarn loops and the fancy yarns are not prone to raveling after damage.

An inkjet recording ink comprising an aqueous medium having dissolved or dispersed therein a magenta dye selected from azo dyes, wherein the magenta dye is a dye having an oxidation potential more positive than 1.0 V (vs SCE) and at the same time, a water-miscible organic solvent having a vapor pressure of 2,000 Pa or less at 20° C. is contained; and an inkjet recording method using the ink. By virtue of such a constitution, an inkjet recording ink and an inkjet recording method are provided, which can ensure high ejection stability, good color hue of the obtained image, no drying of the ink at the ink jet head, excellent fastness to light and water, image quality free from defective such as fineline bleeding under high-humidity condition, and good preservability of the image under severe conditions, and furthermore can ensure high storability and high ejection stability even after aging for a long time or under severe conditions.