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Medicinal composition for treating gynaecologic phlogosis, its production and quality controlling method

A technology of gynecological inflammation and composition, which is applied in the field of traditional Chinese medicine composition for treating gynecological inflammation, and can solve problems such as gastrointestinal discomfort, skin rash, and toxic hepatitis

Active Publication Date: 2007-09-05
江西杏林白马药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this method can temporarily kill bacteria or parasites, it often causes bacterial vaginosis in the vagina, which is difficult to cure for a long time, and has side effects. Hepatitis and other adverse reactions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0138] Raw materials: Dilong 800g, Guan Phellodendron 600g, Sophora flavescens 600g, Cnidium 350g, Clove 350g, Guangdong Zizhu 200g, Wild chrysanthemum 150g

[0139] Preparation: Add 10 times the amount of water to cloves and cnidium, heat and reflux to extract the volatile oil until no oil droplets are produced, and the water liquid is used for later use. The volatile oil is encapsulated with beta-cyclodextrin and set aside; 10 times the amount, decocted twice, 1 hour each time, combined the decoction and the water after oil extraction, filtered, the filtrate was concentrated under reduced pressure to form an extract, added ethanol until the alcohol content reached 40%, and stood overnight. Filtrate, recover ethanol from the filtrate, concentrate under reduced pressure to form a thick paste; add starch to the thick paste, dry, pulverize, mix with beta-cyclodextrin containing volatile oil, granulate, and pack into capsules.

Embodiment 2

[0141] Raw materials: Earthworm 1200g, Guan Phellodendron 900g, Sophora flavescens 600g, Cnidium 650g, Clove 650g, Guangdong Purple Pearl 400g, Wild Chrysanthemum 250g

[0142] Preparation: Add 6 times the amount of water from Clove and Cnidium to extract the volatile oil until no oil droplets are produced, collect the volatile oil and water respectively, and set aside; mix the dregs with the other five flavors such as Guan Phellodendron, add water and decoct 3 times, each time 1.5 hours, combine the decoction and the water after oil extraction, filter, concentrate the filtrate under reduced pressure, add ethanol until the alcohol content reaches 70%, let it stand overnight, filter, recover the ethanol from the filtrate, and concentrate under reduced pressure to form a thick paste; Add 1.5 times the amount of starch to this thick paste, mix and dry, and pulverize; add 3 times the amount of dextrin to the medicinal powder to make granules, dissolve 90% of the volatile oil and sp...

Embodiment 3

[0144] Raw materials: Dilong 800g, Guan Phellodendron 900g, Sophora flavescens 600g, Cnidium 650g, Clove 350g, Guangdong Zizhu 400g, Wild chrysanthemum 150g

[0145] Preparation: Take cloves and cnidium, add 8 times the amount of water, heat to 70°C and soak for 1 hour, continue to heat and reflux to extract the volatile oil for 6 hours, collect the volatile oil and water respectively, and set aside; mix the dregs with the other five flavors such as Phellodendron officinalis, add water Decoct twice, each time for 2 hours, combine the decoction and the water after oil extraction, filter, and concentrate the filtrate under reduced pressure (65~70℃, -0.08MPa) to the immersion oil with a relative density of 1.10~1.12 (60℃). Paste, add ethanol until the alcohol content reaches 50%, let it stand for 6 hours, filter, recover ethanol from the filtrate, concentrate under reduced pressure to a thick paste with a relative density of 1.30-1.35 (60°C), dry, and pulverize into fine powder; ...

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Abstract

A Chinese medicine for treating trichomonas vaginitis, non-specific vaginitis, pudendal itching, etc is prepared from 7 Chinese-medicinal materials including earthworm, flavescent sophora root, cnidum fruit, cloves, etc. Its preparing process and its quality control method are also disclosed.

Description

technical field [0001] The invention discloses a pharmaceutical composition, especially a traditional Chinese medicine composition for treating gynecological inflammation, belonging to the field of traditional Chinese medicine; the invention also discloses a preparation method and a quality control method of the pharmaceutical composition. Background technique [0002] For normal healthy women, due to the characteristics of anatomical tissues, the vagina has a natural defense function against the invasion of pathogens. When the natural defense function of the vagina is damaged, pathogens are easy to invade, and vaginitis will occur. Clinically common vaginitis includes trichomonal vaginitis, candidal vaginitis, bacterial vaginitis, and senile vaginitis. Currently in my country, the incidence of bacterial vaginosis is between 5% and 35%, and the incidence of trichomonal vaginitis is between 19% and 47%. This type II vaginitis is the most common clinical type. The onset of th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/02A61P15/02A61P29/00A61P33/02G01N30/90A61K35/64A61K35/62
Inventor 王乐云
Owner 江西杏林白马药业股份有限公司
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