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867 results about "Skin irritant" patented technology
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Therapeutic/cosmetic compositions comprising CGRP antagonists for treating sensitive human skin
Topically applicable pharmaceutical / dermatological / cosmetic compositions well suited for the therapeutic treatment or care of sensitive human skin, hair, mucous membranes, nails and / or the scalp, in particular for reducing or avoiding the skin-irritant side effects of a variety of bioactive agents, for example the alpha -hydroxy acids, comprise a therapeutically / cosmetically effective amount of at least one calcitonin gene related peptide ("CGRP") antagonist, e.g., CGRP 8-37 or an anti-CGRP antibody.
Owner:LOREAL SA
Zeolite hemostatic dressings and preparation method and application thereof
The invention relates to the high degree of exchange Ca-A type zeolite hemostasis dressing and the preparation method and the purpose. The zeolite hemostasis dressing of the invention containing the zeolite has fast hemostasis speed, and has no bacterium, no pyrogen, no cell toxicity, no hypersensitive reaction and no skin irritation, the using is convenient and the cost is low.
Owner:深圳泰明嘉业药业有限公司
A kind of steroid hormone coating agent and preparation method thereof
ActiveCN102258455ASimple preparation processNo flyingOrganic active ingredientsPharmaceutical delivery mechanismSurvivabilityPlasticizer
The invention relates to a film coating agent containing steroid hormone, which comprises 1 part of steroid hormone medicament, 1-50 parts of film forming materials, 0.5-10 parts of plasticizer, 0.5-10 parts of biological adhesive materials and 1-50 volumes of transdermal enhancer. The preparation of the present invention is capable of raising the efficiency of conveying steroid hormone medicament into the body by permeating skin and improving the irritation to the skin, and has good survivability. The invention also relates to a preparation method of the film coating agent, and the preparation method has the advantages of simple process, convenient operation and less energy consumption.
Owner:上海市生物医药技术研究院
Treatment device and method for treating skin lesions through application of heat
InactiveUS20070049998A1Accelerated deathAssist breakdownDiagnosticsSurgical instruments for heatingMedicineAbscess
Owner:LUMATHERM INC
Nail polish with low stimulation
ActiveCN102552059ALess irritatingDoes not cause soluble corrosionCosmetic preparationsToilet preparationsFiberIrritation
The invention provides a nail polish with low stimulation, which belongs to the cosmetic technical field. The nail polish solves the problems of strong stimulation and easy shedding meeting water of the current nail polishes. The nail polish comprises the following components by weight part: 30-85 parts of alcohols solvent, 10-40 parts of alcohol soluble film forming agent, 1-10 parts of plasticizer, 1-10 parts of thickening agent, 1-10 parts of suspending agent, 0-5 parts of pigment, 0-5 parts of essence and 0-30 parts of solvents besides alcohol. The invention has the advantages that 1, the smell is light, only slight alcohol smell is provided, various essences are added to obtain the fragrance which is analogous with the perfume; 2, the stimulation on nail and skin of the human body is small; 3, dissolvability corrosion can not be caused when the nail polish is contacted with chemical fiber clothes and plastics; 4, the water resistance is excellent, the adhesion of the nail polish of the invention is equivalent with the ester solvent type nail polishes; 6, returning-viscosity is not generated after the nail polish is dried; and 7, the surface brightness of the nail polish of the invention is equivalent with the ester solvent type nail polishes.
Owner:JINHUA MINGSHI TECH
Conductive hydrogel and method of preparing the same
InactiveUS20130270491A1Improve conductivityHigh moistureConductive materialDiagnostic recording/measuringPotassiumPhotoinitiator
A conductive hydrogel includes: a first monomer; a second monomer; a crosslinking agent; a photoinitiator; a wetting agent; an electrolyte; and deionized water, wherein the first monomer is a 3-sulfopropyl acrylate potassium salt, and the second monomer is acrylic acid. The conductive hydrogel has high adhesivity, conductivity and moisture-retaining capacity and low skin irritancy compared to conventional hydrogels because it has the optimum composition ratio.
Owner:BIO PROTECH INC
Polyfunctional hydrocarbon oil composition
ActiveCN101415807AImprove featuresImprove processing efficiencyOrganic non-surface-active detergent compositionsNon-surface-active detergent solventsAlkaneChemical composition
Disclosed is a polyfunctional hydrocarbon oil composition containing a hydrocarbon oil which has a density at 15 DEG C of 0.7-0.8 g / cm<3>, while having an n-paraffin content of 10-90% by mass, an aromatic content of 0-3% by volume and a naphthene content of 0-20% by volume. Also disclosed is a metalworking oil composition, electrical discharge machining oil composition, rust preventive oil composition and cleaning composition, each composed of the hydrocarbon oil composition. The hydrocarbon oil composition is improved in safety such as volatility, inflammability, odor and skin irritation as well as working environment, and performs many functions.
Owner:NIPPON OIL CO LTD
APG (alkyl polyglucoside) plant environmentally-friendly shampoo
InactiveCN102210644AReduce surface tensionStrong wetting powerCosmetic preparationsHair cosmeticsIrritationSkin irritant
The invention discloses an APG (alkyl polyglucoside) plant environmentally-friendly shampoo which comprises APG (alkyl polyglucoside), coconut oil 6501, water-soluble wool grease, cocamidopropylamine oxide, emulsified silicon oil softener, EDTA (ethyle, diamine tetraacetic acid), citric acid, sodium alginate, Germall, plant additive and water. The APG plant environmentally-friendly shampoo has the effects of effectively resisting hair dropping, blacking hair, shinning hair, nourishing hair, sterilizing, removing dandruff and relieving itching, has small skin irritation, and does not produce drug resistance after being used for long term.
Owner:董家华 +1
Non-irritating solvent-borne polymeric coatings for application to the skin
InactiveUS20070048355A1Accelerate the rate of drying of such coatingsStinging and burning problem isBiocideOrganic active ingredientsLiquid mediumKetone
A method and composition for reducing or eliminating stinging that may accompany application of topical solution of a skin-compatible polymeric material to a skin wound, abrasion, burn or other skin injury. The topical solution may contain one or more skin-irritating chemicals, such as diethyl ether, ethanol, ethyl acetate, methyl acetate, acetone, methyl ethyl ketone and combinations thereof. The method includes: (i) providing a composition that contains between 1% and 10% by weight of the skin-compatible polymeric material dissolved in a liquid medium suitable for human topical use in which the liquid medium includes less than 20% combined weight of skin-irritating chemicals, and at least 45% combined weight of at least one volatile solvent and / or volatile co-solvent, in which the molecules constituting this 45% combined weight portion of the liquid medium contain at least 5 carbon atoms, and the liquid medium has an initial boiling point at 1 atmosphere of greater than 35° C. and less than 150° C., and causes little or no stinging when applied to a skin injury, and (ii) applying the composition to the skin of a patient at the site of the skin injury.
Owner:PERLMAN DANIEL
Multifunctional moist towelette
ActiveCN102551580ALess irritatingNo side effectsCosmetic preparationsToilet preparationsIrritationMENTHOL CRYSTALS
The invention discloses a multifunctional moist towelette which comprises a flexible platy fiber carrier, wherein the flexible play fiber carrier is rich in multifunctional liquid medicine, and the multifunctional liquid medicine contains the following components according to weight percentage: 8-10% of deodorized ethanol, 1.5-2.7 % of humectant, 0.1-0.3 % of solubilizer, 0.2-0.4 % of emulsifier, 0.3-0.4 % of preservative, 84.28-76.59 % of purified water, 5-8 % of dimethyl phthalate, 0.3-0.5 % of mosquito repelling plant extract, 0.02-0.03 % of menthol crystal, 0.2-0.5 % of vitamin E, and 0.1-0.5 % of aloe vera gel; the pH value of the multifunctional liquid medicine is 5.6-6.5; the mosquito repelling plant extract is an extract obtained in a way that one or multiple of citronella, folium artemisiae argyi and mozzie buster is subjected to supercritical carbon dioxide extraction or an essential oil extractor method or a physical soaking and extracting method. The multifunctional moist towelette has less irritation to skin, is suitable for sensitive skins, has lasting mosquito repelling effect and has various health-care functions to skin, such as diminishing inflammation, preserving moisture, resisting ageing, easing pain and relieving itching.
Owner:纳奇科化妆品有限公司
Chinese medicinal shinyleaf prickly ash root nourishing and itch-relieving shower gel
ActiveCN102579307ABasic CleansingMild performanceCosmetic preparationsToilet preparationsPolyolShower gel
The invention discloses a Chinese medicinal shinyleaf prickly ash root nourishing and itch-relieving shower gel, and relates to the technical field of daily chemical products. The shower gel is prepared from a cationic surfactant, an anionic surfactant, a conditioner, a nonionic surfactant, an ampholytic surfactant, a polyol moistening agent, a pearling agent, shinyleaf prickly ash root extract, natural tea extract, high-efficiency nourishing components, citric acid, sodium citrate, sodium chloride, essence, Kathon and proper water. The shower gel has basic cleaning effect, mild performance, low irritation to skin, and can be used for effectively nourishing skin, eliminating skin tension after shower and effectively relieving itch.
Owner:LMZ YANGZHOU HOTEL SUPPLIES +2
YB microbe function fungus and domestic organic garbage treating machine
Owner:上海神微再生资源股份有限公司
Low irritation antimicrobial cleaning substrate
The transfer of antimicrobial agent from a cleaning substrate to the skin can be reduced resulting in reduced skin irritancy when the viscosity of the cleaning composition containing the antimicrobial is increased in viscosity. The transfer is measured by the Simulated Hand Transfer Method. The cleaning substrate is used to clean hard surfaces, especially bathroom surfaces such as toilets, and is attached to a cleaning implement. Also provided is a method of promoting a product having reduced skin irritancy.
Owner:THE CLOROX CO
Antimicrobial and antiseptic methods using antimicrobial composition
InactiveUS6159999ASuppressing skin irritationImprove stabilityBiocideHydroxy compound active ingredientsSolventSkin irritant
An antimicrobial composition is provided in which the skin irritation of isothiazolone type compound is decreased and the injection operation properties thereof is improved by forming it as an uniform solution. The composition contains isothiazolone type compound and a compound which decreases the skin irritation of the former in a molar ratio of 1:0.1-50 and is dissolved in a solvent.
Owner:KURITA WATER INDUSTRIES LTD
Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions
Botanically derived anti-irritants for prophylactic and therapeutic treatment of adverse skin reactions from application of transdermal or topical drug delivery system, permits the effective administration of a drug from a delivery system in which the drug, of a component of the delivery system comprises a skin irritant; and the delivery systems formed thereby.
Owner:MORNINGSIDE VENTURE INVESTMENTS
Skin covering sheet for cosmetic preparation impregnation and process for producing the same, and face mask using said sheet
ActiveCN101010017ALess irritatingNot unpleasantCosmetic preparationsLayered productsWater flowNonwoven fabric
This invention provides a covering sheet for cosmetic preparation impregnation, which is suitable for face masks and the like, is less likely to cause skin irritation, and has good applicability. A splitting-type composite fiber web comprising not less than 50% by mass of a splitting-type composite fiber is arranged on one or both surfaces of a hydrophilic nonwoven fabric comprising not less than 50% by mass of a hydrophilic fiber, and hydroentangling treatment is carried out to split the splitting-type composite fiber and to form an ultrafine fiber layer comprising not less than 10% by mass of an ultrafine fiber having a fineness of not more than 0.5 dtex, and, in addition, the hydrophilic nonwoven fabric is integrated with the ultrafine fiber layer to form a sheet. The sheet is impregnated with a cosmetic preparation, and the impregnated sheet is used in such a manner that the ultrafine fiber layer functions as a surface of contact with the skin.
Owner:DAIWABO HLDG CO LTD +2
Face cosmetic
InactiveCN101496775AUnique formulaFormulation InnovationCosmetic preparationsToilet preparationsIrritationGluconic acid
The invention provides a facial make-up with excellent effect on moisturizing, whitening and nourishing and small irritation to skin. The facial make-up consists of make-up substrate and make-up active substances, wherein the make-up active substances comprise glycolic acid, kojic acid, arbutin, aloin, baicalin, paeoniflorin, glycyrrhizic acid, squalane, hyaluronic acid and chitin to be prepared into toner, facial cream, facial cleanser, facial mask, gel and external soft capsule preparations.
Owner:徐伟玲
Dispersing dye mixture and dye products
The invention relates to a dispersing dye mixture and the dye products that has no thrill to skin and has good application capability. The feature is that the mixture at least contains a kind of dye compounding of formula (I) and a kind of dye compounding of formula (II).
Owner:ZHEJIANG JIHUA GROUP +1
Pigment-containing artificial skin detection model and preparation method thereof
The invention relates to a pigment-containing artificial skin detection model and a preparation method thereof. The artificial skin detection model is an epidermal layer structure with activity, which is constructed by compositely inoculating cutin formative cells and melanophores to the surface of a support membrane made from a biodegradable material through culture and comprises a stratum basale, a stratum spinosum, a stratum granulosum and a stratum corneum, and a basilar membrane structure is formed between the epidermal layer and the biodegradable material positioned below the epidermal layer. Compared with the conventional product, the invention can better simulate the pigment components of natural skin and more accurately reflect the whitening and sunscreen effect of cosmetics because of containing the melanophores, nourish the cutin formative cells by using the support membrane made from the biodegradable material as an enderonic layer, control the contraction of the epidermal layer with the strength and enhance the stability of the detection model and has low raw material cost, short manufacturing period and mass production; and in addition, the prepared artificial skin detection model can be directly used for the efficacy detection of the cosmetics and the skin irritation detection of textiles, the cosmetics and chemicals.
Owner:GUANGDONG BOXI BIO TECH CO LTD
Medical pressure-sensitive adhesive composition, process for producing the same, and medical tape
InactiveUS20050080195A1Reduce skin irritationImprove compatibilitySurgical adhesivesPlastersCross-linkOligomer
A medical pressure-sensitive adhesive composition having excellent re-adhesion property, and also excellence in both the peel adhesion property and the low skin stimulus property, a process for producing the same, and a medical tape are provided. In the medical tape, a medical pressure-sensitive adhesive composition containing acrylic polymer and acrylic oligomer is laminated on a substrate, wherein the medical pressure-sensitive adhesive composition is prepared by cross-linking an intermediate composition containing an acrylic polymer having a cross-linkable functional group and an acrylic oligomer containing 10 to 40 percent by mole of vinyl monomer with a lactam ring through the use of a cross-linking agent, and wherein this medical tape is made by compounding the acrylic oligomer in the range of 50 to 700 parts by weight relative to 100 parts by weight of acrylic polymer, while the number average molecular weight of the acrylic polymer is set at a value within the range of 300,000 to 1,500,000, and the number average molecular weight of the acrylic oligomer is set at a value within the range of 1,000 to 10,000.
Owner:LINTEC CORP +1
Cleaning agent composition and preparation method thereof
ActiveCN101942364AEfficient removal effectGood removal effectInorganic/elemental detergent compounding agentsCationic surface-active compoundsPotassium hydroxideOxygen
The invention provides a cleaning agent composition and a preparation method thereof. The cleaning agent composition comprises the following components in percentage by weight: 1 to 10 percent of fatty acid salt anionic surfactant, 1 to 10 percent of polyoxyethylene type nonionic surfactant, 1 to 10 percent of quaternary ammonium salt cationic surfactant, 1 to 5 percent of sodium hydroxide or potassium hydroxide, 20 to 50 percent of glycol ether solvent and 20 to 50 percent of water. The product has the advantages of reasonable formula, good cleaning effect on heavy oil dirt, low alkali and organic solvent content, low irritation to the skin, high safety and low cost. The preparation method for the cleaning agent composition comprises the following steps of: weighing the sodium hydroxide or the potassium hydroxide, and adding the sodium hydroxide or the potassium hydroxide into the water for dissolving with stirring to form alkali solution; and adding the fatty acid salt anionic surfactant into the prepared alkali solution, dissolving the anionic surfactant with stirring, then adding the polyoxyethylene type nonionic surfactant and the quaternary ammonium salt cationic surfactant into the solution in turn, adding the glycol ether solvent into the solution, and stirring the solution uniformly.
Owner:中山榄菊日化实业有限公司
Biological environment-friendly hair-darkening and hairloss-preventing shampoo and preparation method thereof
InactiveCN102415971AReduce surface tensionStrong wetting powerCosmetic preparationsHair cosmeticsBetaineIrritation
The invention discloses biological environment-friendly hair-darkening and hairloss-preventing shampoo and a preparation method thereof. The shampoo contains alkyl polyglucoside (APG), coconut oil, water soluble wool oil, cocoamido propyl betaine, tea seed oil, ethylenediaminetetraacetic acid (EDTA) disodium, citric acid, sodium alginate, genma and plant hair-darkening and hairloss-preventing essence. The shampoo can effectively prevent hair loss, darken and brighten hair, remove dandruff and relieve itching, is less irritant to skin and can be used for a long time without causing medicine resistance.
Owner:广州迪普威生物科技有限公司
Skin care product with sunscreen and sun repair functions and preparation method thereof
ActiveCN106420471AMild effectImprove securityCosmetic preparationsToilet preparationsAdditive ingredientIrritation
The invention belongs to the technical field of cosmetics, and relates to a skin care product with sunscreen and sun repair functions and a preparation method thereof. The skin care product with the sunscreen and sun repair functions comprises the following components: sodium copper chlorophyllin, cytokine complex liposome, an asparagus extract, a flos lonicerae extract, an ash bark extract, dipotassium glycyrrhizinate, shea butter, butanediol, beta-glucan, sodium hyaluronate, xanthan gum, trehalose, hydrogenated jojoba oil, squalane, cyclopentasiloxane, cetearyl glucoside, cetearyl alcohol, PEG-100 stearate, tocopheryl acetate, bisabolol, a preservative, essence and deionized water. The skin care product with the sunscreen and sun repair functions, provided by the invention, is reasonable in formula, stable in property, mild in effect and free from skin irritation and has the obvious sunscreen and sun repair functions under the synergistic action of the various effective components.
Owner:广东省科玮智丽生物医药有限公司
Transdermally absorbable donepezil-containing preparation
InactiveUS20130053358A1Reduce skin irritationSufficient rateBiocideNervous disorderDonepezilSkin permeability
Provided is a transdermal preparation having low skin irritation as well as a sufficient skin permeability rate of donepezil, which comprises one or more drugs selected from donepezil and pharmaceutically acceptable salts thereof. Also provided are a manufacturing method thereof, and a method for reducing skin irritation of a transdermally absorbable donepezil-containing preparation. An embodiment is a transdermal preparation comprising one or more drugs selected from donepezil and pharmaceutically acceptable salts thereof, and a skin irritation-reducing agent.
Owner:HISAMITSU PHARM CO INC
Tripterygium glycoside-containing micro-emulsified gel transdermal preparation and preparation method thereof
InactiveCN102462723ASimple manufacturing processImprove product qualityAntipyreticAnalgesicsActive agentSurface-active agents
The invention belongs to the technical field of medicinal preparations and relates to a tripterygium glycoside-containing micro-emulsified gel transdermal preparation and a preparation method thereof. The preparation method is characterized in that a gel matrix is added into microemulsion and the mixture is further processed into the tripterygium glycoside-containing micro-emulsified gel transdermal preparation. The tripterygium glycoside-containing micro-emulsified gel transdermal preparation comprises: by mass, 0.1 to 15% of tripterygium glycoside, 15 to 20% of one or more surfactants, 30 to 40% of one or more auxiliary surfactants, 15 to 25% of oil phases, 15 to 25% of water, 0.5 to 2% of one or more transdermal absorption promoters, and 0.5 to 5% of one or more gel base materials. Thetripterygium glycoside-containing micro-emulsified gel transdermal preparation is semitransparent or transparent, has nattier blue opalescence and a pH value of 6 to 10 and can form micro-emulsion having particle sizes of 10 to 100nm, can be processed into pasters so that drug transdermal delivery is realized, has low skin irritation, can be prepared by the simple preparation method, and has stable quality and good drug transdermal absorption promotion performances.
Owner:FUDAN UNIV
Skin care composition with wrinkle removing and resisting function and preparation and preparation method thereof
ActiveCN102048666ADPPH free radical scavenging ability is strongPromote absorptionCosmetic preparationsToilet preparationsIrritationStratum basale
The invention discloses a skin care composition with a wrinkle removing and resisting function. The composition comprises a phase A and a phase B, wherein the phase A comprises oil, and the phase B comprises traditional Chinese medicine extracts. In the invention, raw materials are all selected from natural soothing components, have little stimulation to the skin, permeate into the skin stratum basale through various approaches and can be used for recovering skin activity and removing free radicals so as to fundamentally play the roles of removing and resisting wrinkles. Experiments prove that the preparation of the skin care composition has an obvious wrinkle removing function, and can obviously improve the texture of the skin, make the texture fine and smooth, simultaneously enhance skin glossiness and make the skin fin, mellow and white after being used for 30 days. The skin care composition disclosed by the invention is prepared from the raw materials which are easy to obtain by a convenient preparation method, is easy to accept by the massive consumers and has good application prospects and market prospects.
Owner:NEW ERA HEALTH IND GRP +2
Topical formulation
ActiveUS20110028460A1Improve throughputBiocidePeptide/protein ingredientsSodium acetateSODIUM LAURYL SULFOACETATE
It has been discovered that certain combinations compounds are excellent penetration enhancers and, as such, can be incorporated in a topical formulation to facilitate administration of active agents. The increased penetration enhancement can also lead to a reduction in the total concentration of skin irritants in the formulation. There is described herein a topical formulation comprising (i) at least one active agent; (ii) a first compound, and (iii) a second compound, wherein the first compound and second compound are different, and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate and sodium lauryl sulfoacetate.
Owner:CRESCITA THERAPEUTICS INC
Pentacyclic triterpenoid cyclodextrin clathrate compound proliposome and preparation method thereof
ActiveCN102871848ALess irritatingEasy to useCosmetic preparationsBody powdersCholesterolBetulonic acid
Owner:西安雅芝生物科技有限公司
Chinese medicinal composition with acne treatment and anti-inflammation effects, preparation and preparation method thereof
ActiveCN102068498ALess irritatingNo dependenciesCosmetic preparationsToilet preparationsHoneysuckleSkin irritant
The invention discloses a Chinese medicinal composition with acne treatment and anti-inflammation effects. The composition is mainly prepared from the following raw materials in part by weight: 35 to 45 parts of root of red-rooted salvia, 15 to 20 parts of honeysuckle flower, 15 to 25 parts of clove, 10 to 15 parts of officinal magnolia bark and 10 to 15 parts of rhubarb. The raw materials contain natural soothing components, have low skin irritation and realize an acne treatment effect in various ways. Compared with the same type of products in the conventional market, the composition is safer, efficient and independent (without antibiotics or chemical medicament components); and raw materials are readily available, different dosage forms can be taken as carriers and a preparation methodis convenient. The composition has low cost, good effect, good application prospect and market prospect, and is easily accepted by customers.
Owner:NEW ERA HEALTH IND GRP +2
Iodine disinfection liquid and preparation method thereof
InactiveCN102550601ANo adverse effect test bacteriaNo adverse effects on cultivationBiocideFungicidesCommon objectSkin irritant
The invention discloses iodine disinfection liquid and a preparation method thereof. The iodine disinfection liquid comprises the following medical raw materials in proportion by weights: 4-65 g of povidone iodine, 0.05-0.15 g of potassium iodate, 4-8 g of sodium dihydrogen phosphate, 1-3 g of disodium hydrogen phosphate, suitable amount of 10% sodium hydroxide and purified water added to 1000 mL. The iodine disinfection liquid disclosed by the invention is suitable for skin disinfection and mucous membrane (oral cavity and the like) disinfection, disinfection of surgical hand washing and healthy hand washing, disinfection of fire burn and wound and disinfection of surfaces of common objects. The iodine disinfection liquid disclosed by the invention has the advantages of low skin irritation, low toxicity, action durability, safety, convenience and simpleness for use as well as steady quality.
Owner:昆明振华制药厂有限公司
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