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587 results about "Skin irritation" patented technology

Method and system for evaluating anus cleaning effect

The invention belongs to the technical field of biological simulation, and discloses an anus cleaning effect evaluation method and system.The method comprises the steps that an execution assembly is controlled to wipe an anus anatomical structure with a to-be-detected sample according to a target wiping strategy, and a multi-mode sensing assembly is controlled to collect target parameters on the anus anatomical structure; obtaining target monitoring data; according to the residual dirt amount in the target monitoring data, a cleaning efficiency score is obtained through calculation, a target mechanical simulation model is called, according to the humidity permeation gradient value and the pressure value in the target monitoring data and the to-be-detected sample, a skin stimulation risk score is obtained through calculation, and the skin stimulation risk score and the cleaning efficiency score form a cleaning effect evaluation report. Simulation and prediction of the anus cleaning process are achieved, the simulation test effect and accuracy are greatly improved, and a cleaning effect evaluation report is given to illustrate the safety of the to-be-tested sample.
Owner:YIXIANG HEALTH TECHNOLOGY (CHONGQING) CO LTD +1

Fluralaride moxidectin composite drop and preparation process thereof

The invention relates to the technical field of medicine formulas, in particular to a fluralamide moxidectin composite drop and a preparation process thereof. The invention relates to a fluralan-moxidectin emulsion which is prepared from the following raw materials in percentage by mass: 26 to 30 percent of fluralan, 1.1 to 1.7 percent of moxidectin, 32 to 36 percent of solvent, 0.1 to 0.3 percent of butylated hydroxytoluene, 10 to 16 percent of polymer carrier and the balance of tetrahydrofuran polyethylene glycol ether. The coexisting drug is stabilized through the core-shell structure polymer carrier, phase separation is prevented, a neutral environment is maintained, long-acting stability is ensured, the transdermal absorption rate is optimized, skin irritation is reduced, and the synergistic drug effect is improved. Meanwhile, the slow release period of the medicine is prolonged, the metabolic interference and accumulated toxicity are reduced, and the dissolution efficiency and the skin mildness are both considered.
Owner:QINGDAO BOLIN BIOLOGICAL TECH CO LTD

Application of platelet reaction protein 4 in preparation of medicine for treating alopecia

The invention relates to application of a platelet reaction protein 4 in preparation of an alopecia medicine, and belongs to the field of medical biology. The invention aims to solve the technical problems of limited curative effect, obvious side effect and narrow application range of the existing alopecia treatment medicine. The invention provides an application of a platelet reaction protein 4 (THBS4) in preparation of an alopecia medicinal preparation, which can promote hair follicles to be converted from a resting period to a growing period by regulating and controlling a mechanical microenvironment around the hair follicles, enhancing the interaction between fibroblasts and hair follicle stem cells and activating regeneration signal channels in hair papilla and hair bud areas. The traditional Chinese medicine composition breaks through the limitation that existing treatment only aims at specific alopecia types, and can be widely applied to various alopecia diseases such as androgenetic alopecia, pressure alopecia and alopecia after chemotherapy. And compared with the traditional medicine, the traditional Chinese medicine composition has the advantages of quick response, no skin irritation reaction and improved hair follicle regeneration efficiency, and provides a brand new solution for safe and efficient treatment of alopecia.
Owner:CHONGQING UNIV

Medical Access Garment with Extended Two-Way Zippers

An adaptive medical access garment comprising a torso portion configured to cover at least a portion of a wearer's upper body and two sleeve portions extending from the torso portion. Each sleeve portion includes an extended two-way zipper extending continuously from a distal end of the sleeve to the torso portion, terminating proximate to the wearer's clavicle or chest. The garment is constructed from hypoallergenic, breathable fabric to ensure patient comfort and minimize skin irritation risk. The extended two-way zippers enable medical professionals to access the wearer's arms and upper body without requiring garment removal. The garment may further comprise thumb holes at the sleeve distal ends, pockets for holding medical devices, and side slits on the torso portion for accessing the wearer's sides. The invention encompasses a method for providing the adaptive medical garment.
Owner:DEMPSEY JASON

Female and child skin care composition and preparation method thereof

The invention relates to a skin care composition for women and children and a preparation method thereof. The composition comprises the following components: tremella fuciformis extract nanocrystals, a calendula extract, an oat extract, dipotassium glycyrrhizinate, panthenol, sodium hyaluronate and the like. By using a nanocrystalline technology and a compound stabilizer, the moisturizing and anti-oxidation effects of the product are remarkably improved, and the product is suitable for various skins, especially sensitive skins. The product is safe and mild, effectively reduces skin irritation and improves the skin barrier function. The problems that an existing skin care product is not lasting in moisturizing effect and insufficient in oxidation resistance are solved, and an efficient and stable skin care solution is provided.
Owner:JIANGSU FAMOUS MEDICAL TECH CO LTD

Bionic artificial limb with knee-ankle linkage function

The invention relates to the technical field of active artificial limbs, in particular to a bionic artificial limb with a knee-ankle linkage function. Comprising a fixing frame, a receiving cavity is connected to the fixing frame, first air bags are arranged on the inner side of the receiving cavity at intervals, clamping blocks are connected to the first air bags at intervals, air escape valves are arranged on the first air bags, an air conveying mechanism is arranged on the fixing frame, and the air conveying mechanism is used for alternately conveying air into the different first air bags. The first air bags with the clamping blocks are combined with the air conveying mechanism, so that the first air bags can be alternately expanded and deflated, intermittent fixation and relaxation of limbs are achieved, blood circulation disorder caused by long-time continuous compression of a traditional rigid or semi-rigid receiving cavity is effectively avoided through the dynamic adjusting mode, and the medical treatment effect is improved. The probability of occurrence of complications such as skin irritation, redness and swelling and even pressure sores is remarkably reduced, and the wearing comfort and safety are improved.
Owner:HENAN JIANQI MEDICAL DEVICES CO LTD

Plant-extracted external liniment for promoting black hair growth and preparation method of plant-extracted external liniment

The invention relates to a phytoextraction external liniment for promoting black hair growth and a preparation method thereof. According to the liniment, a polygonum multiflorum extract, a cacumen biotae supercritical extract and molecular embedded black sesamin in a specific proportion are taken as cores and are matched with an azone-menthol transdermal enhancer and a propylene glycol-olive oil carrier, and black hair growth is synergistically promoted through triple mechanisms of activating tyrosinase, inhibiting melanocyte apoptosis and promoting cell migration. The preparation method adopts a gradient temperature extraction combined molecular embedding technology, the polygonum multiflorum is subjected to stepped purification at 40-60 DEG C-80 DEG C to retain thermosensitive active ingredients, the black sesamin is embedded by beta-cyclodextrin to improve the stability, and finally, the nano microemulsion is formed through two-stage homogeneous emulsification. The liniment can efficiently permeate into the deep layer of hair follicles, the efficiency of turning white hair into black is remarkably improved, and skin irritation is avoided.
Owner:广西丽竹企业管理集团有限公司

Whitening compound as well as preparation method and application thereof

The invention discloses a whitening compound as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The structural formula of the whitening compound is as follows: # imgabs0 #, R1 and R2 independently comprise alpha glucoside, beta glucoside or phenolic hydroxyl groups, and R1 and R2 are not phenolic hydroxyl groups at the same time. The whitening compound has higher stability, is not easy to generate self-oxidation reaction, and is beneficial to prolonging the shelf life of the product and prolonging the durability of the whitening effect; moreover, the whitening compound is suitable for sensitive skin, and can reduce skin irritation and reduce adverse reactions such as red and swollen, stabbing pain, dryness and the like; in addition, the whitening compound can promote proliferation of beneficial bacteria on epidermis, and can improve or improve the skin whitening effect to a certain extent.
Owner:OSMUN BIOLOGICAL CO LTD

Low-irritation cyhalothrin as well as preparation method and application thereof

PendingCN120283752ABiocideAnimal repellantsAllergic antiAnti-Allergic Agents
The invention discloses low-irritation cyhalothrin and a preparation method and application thereof, and belongs to the technical field of pesticide preparations, the low-irritation cyhalothrin comprises silicon dioxide nanoparticles with the surfaces grafted with amphiphilic copolymers, cyhalothrin and an anti-allergic drug, the silicon dioxide nanoparticles with the surfaces grafted with the amphiphilic copolymers are dispersed in a solvent, and the anti-allergic drug is added to the silicon dioxide nanoparticles with the surfaces grafted with the amphiphilic copolymers to prepare the low-irritation cyhalothrin. The preparation method comprises the following steps: taking porous silicon dioxide nanoparticles as a carrier, modifying a layer of amphiphilic polymer on the surface of silicon dioxide in situ, then adding cyhalothrin and an anti-allergic drug, continuously stirring, and drying the obtained product to obtain the low-irritation cyhalothrin. The cyhalothrin and the anti-allergic drug are loaded in silicon dioxide pore channels, and the anti-allergic agent is used in cooperation, so that the skin irritation of the cyhalothrin is reduced. The cyhalothrin with low irritation provided by the invention is simple in preparation method, can be used as a cyhalothrin insecticide raw medicine, and has relatively great market application potential.
Owner:ANHUI NUMAI NEW MATERIALS TECHNOLOGY CO LTD

Sleep-aiding essential oil formula containing cedar himalaya

The invention provides a formula of sleep-aiding essential oil containing cedar himalaya, relates to the technical field of sleep-aiding essential oil, and aims to solve the problems of single effect, poor stability and insufficient skin tolerance of existing sleep-aiding essential oil. The formula comprises the following components in parts by weight: 0.5-5 parts of Himalaya cedar essential oil, 80-95 parts of base oil, 1-10 parts of synergistic sleep-aiding essential oil, at least one of lavender essential oil, chamomile essential oil and sandalwood essential oil, and 0.1-1 part of optional antioxidant. During preparation, the components are ensured to be uniform through a process of stirring at a constant temperature of 25-35 DEG C and mixing at a rotating speed of 200-300rpm, the pH value of the product is 5.5-7.0, the retention rate of the active components is greater than or equal to 90% after the product is stored in a dark place at 25 DEG C for 6 months, and the use mode is that the product is smeared on wrists / necks / soles 1-2 hours before sleep, and 0.5-2mL of the product is smeared on each time. Tests show that the sleep time of insomnia people can be shortened to 15-22 min after the essential oil is continuously used for 28 days, the PSQI score is reduced by 40%-54%, the skin irritation is zero, the essential oil is suitable for preparing external sleep-aiding essential oil cream, ball bottles and other products, and a safe and efficient solution is provided for sleep disorder people.
Owner:GUANGZHOU DINGJIN TECH CO LTD

Cosmetic delivery system based on natural wall material, preparation method and application

The invention belongs to the technical field of cosmetics, and particularly relates to a cosmetic delivery system based on a natural wall material, a preparation method and application. The cosmetic delivery system is of a core-shell structure, a core is a cosmetic active component, and a shell layer is a composite polymer gel network of sodium alginate, sophorolipid and cellulose. The natural polysaccharide composite wall material is green and safe, has good biocompatibility and strong compatibility with cosmetic formulas, and does not irritate the skin. The delivery system can effectively protect cosmetic active ingredients from being damaged by illumination and oxygen, and the storage stability of the active ingredients is remarkably improved; meanwhile, slow release and targeted transdermal absorption of active ingredients are realized, and the bioavailability is improved.
Owner:GUANGZHOU SHIFEI BIO-TECH CO LTD

Oil-in-water type sunscreen product and preparation method thereof

The invention discloses an oil-in-water type sunscreen product and a preparation method thereof, and belongs to the technical field of cosmetics. The oil-in-water type sunscreen product is prepared from the following components in parts by weight: 0.01 to 1 part of thickening agent and 0.01 to 5 parts of dispersion stabilizer, wherein the thickening agent comprises carbomer, an acrylic acid (ester) / C10-30 alkanol acrylate cross-linked polymer and a hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer; the dispersion stabilizer is prepared from disteardimonium hectorite and polyhydroxystearic acid. The oil-in-water type sunscreen product has the advantages of good sunscreen effect, good stability, small skin irritation, fresh and cool skin feeling and good conformity. The preparation method comprises the step of mixing the preparation raw materials of the oil-in-water type sunscreen product according to a preset ratio, and the method is simple, easy to operate and suitable for industrial production.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Mild oil-purifying acne-removing cleaning composition and application thereof

PendingCN120305153ACosmetic preparationsHair cosmeticsShower gelPotassium palmitate
The invention discloses a mild oil-purifying acne-removing cleaning composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The cleaning composition is prepared from the following components in parts by weight: 15 to 35 parts of water / potassium cocoyl glycinate, 10 to 30 parts of water / potassium cocoate, 1 to 10 parts of water / potassium palmitate, 0.1 to 5 parts of water / sodium PEG-7 (Polyethylene Glycol) olive oil carboxylate, 0.1 to 10 parts of water / glycolipid and 0.01 to 1 part of water / glycosylglycerol / 1, 2-pentanediol. According to the cleaning composition disclosed by the invention, all the components are matched according to a specific proportion, so that the cleaning composition has mild and efficient oil-purifying and acne-removing effects. Various surfactants such as potassium cocoyl glycinate and the like have a synergistic effect, so that the skin irritation is reduced while the cleaning power is ensured; special functional components such as glycolipid further optimize the cleaning, moisturizing and acne removing effects. The preparation method comprises the following steps: firstly, mixing part of the components, heating to 70-90 DEG C, uniformly stirring, cooling to 40-45 DEG C, adding the rest of the components, and cooling to 30-35 DEG C to obtain a final product with the pH value of 7-8.5. The composition can be widely applied to various cleaning products such as facial cleanser, scrub cream, shower gel and the like, provides an innovative solution for the field of skin cleaning and nursing, meets the requirements of consumers on mild and effective oil-purifying and acne-removing cleaning products, and has a wide market application prospect.
Owner:SUZHOU WEILAN BIOTECHNOLOGY CO LTD

Phase-change microcapsule capable of intelligently adjusting temperature and preparation method of fabric of phase-change microcapsule

The invention belongs to the technical field of textile fabrics, and discloses an intelligent temperature-adjusting phase change microcapsule and a preparation method of a fabric thereof. The phase change microcapsule is prepared from the following components in percentage by mass: 60 to 80 percent of organic phase change material, 6 to 15 percent of N-isopropylacrylamide, 4 to 10 percent of acrylic acid, 1 to 5 percent of polyether surfactant, 2 to 5 percent of urethane acrylate and 2 to 5 percent of initiator. Warp yarn, first weft yarn and second weft yarn containing the microcapsules are woven into the intelligent temperature-adjusting phase-change fiber fabric, the response speed of the phase-change microcapsules is increased through the thermosensitivity of the organic phase-change materials, temperature can be buffered and adjusted in a wide temperature range, the organic phase-change materials cooperate with the temperature-sensitive polymer capsule wall, heat release, warm keeping, ventilation and moisture removal are achieved, and the intelligent temperature-adjusting phase-change fiber fabric is obtained. Inlet of hot air is reduced through heat absorption and cooling, climate and air temperature adjustment is self-adapted, and somatosensory comfort is maintained. In addition, no components irritating to the skin are added in the formula, so that adverse reactions such as sensitization and the like on consumers are avoided.
Owner:LANXI SUBLIMATION TEXTILE

Personal protective equipment and methods

Improved personal protective equipment facial wear including, in one embodiment, an at least partly adhesive mask, and one or more adhesive eye shields. In one implementation, the mask avoids significant contact with the delicate periorbital skin of the wearer, yet provides a substantially airtight seal so as to preclude moisture vapor transfer and “fogging” of eyeware or instruments. In another implementation, adherence of the eye shield is at least partially overlapping with the mask and creates an at least partial seal around a perimeter of the eye shield. Further, an at least partial seal is formed around a perimeter of the mask. The mask and eye shield additionally prevent nasal air flow obstruction, and address the problem of skin irritation and attachment during normal facial expression and movement of the wearer.
Owner:MDIDEAFACTORY

Preparation method of black drill truffle oil composition and application of black drill truffle oil composition in cosmetics

PendingCN120918998ACosmetic preparationsToilet preparationsBiotechnologyMeadowfoam seed oil
The invention discloses a preparation method of a black drill truffle oil composition and application of the black drill truffle oil composition in cosmetics. The composition comprises the following components in percentage by mass: 6-10% of perigord truffle oil, 18-25% of decolorized sea buckthorn fruit oil, 15-20% of sunflower seed oil and the balance of meadowfoam seed oil. The perigord truffle oil is obtained by adopting CO2 supercritical extraction to extract perigord truffle sporocarp. The composition has multiple excellent effects of resisting oxidation, resisting aging, preserving moisture, repairing skin barrier and the like. In-vitro DPPH free radical scavenging experiments and human body efficacy tests prove that the product has extremely remarkable effects in the aspects of increasing the skin moisture content, reducing transdermal moisture loss and the like, is free of skin irritation and untoward effects, is suitable for cosmetics, is particularly suitable for high-end skin care product formulas such as eye essence, facial essence and skin care oil, and has a very good application prospect. The anti-aging, repairing and moisturizing properties of the product can be obviously improved.
Owner:GUANGZHOU GAOTAI BIOTECHNOLOGY CO LTD

Acne-removing skin-care conditioning oil and preparation method thereof

PendingCN120458965ACosmetic preparationsAntipyreticGinger root oilAllergic reaction
The acne-removing skin-care conditioning oil is prepared from the following components in parts by weight: 90 to 95 parts of sweet almond oil, 0.5 to 1.5 parts of ginger root oil, 0.5 to 1.5 parts of peppermint oil, 1.5 to 2.5 parts of lemon peel oil, 1 to 1.5 parts of eucalyptus globulus leaf oil and 2 to 3 parts of lemongrass leaf oil. The invention also discloses a preparation method of the acne-removing skin-care conditioning oil. The acne-removing skin-care conditioning oil disclosed by the invention is small in skin irritation, wide in universality and few in allergic phenomenon, and can also achieve the effects of repairing and skin care while removing acnes.
Owner:FEILANG BIOTECHNOLOGY (HUBEI) CO LTD

Blue copper peptide composition with instantaneous cool feeling and permeation enhancing effect as well as preparation method and application of blue copper peptide composition

The invention relates to the field of cosmetics, in particular to a blue copper peptide composition with instantaneous cool feeling and infiltration promotion effects and a preparation method and application of the blue copper peptide composition. The composition comprises an active component copper-blue peptide and a cooling and permeation enhancing system formed by compounding at least two of menthane formylethylamine, menthone glyceryl ketal and methyl diisopropyl propionamide, and the active component can further comprise hexapeptide-11, a blue algae extract and a yeast fermentation product. The preparation method of the composition comprises three core steps of providing a water phase, adding the active ingredients and adding the cool and refreshing infiltration promoting system and other components. Through synergistic compounding of specific fresheners, on the premise that the use amount of each single component is remarkably reduced, efficient permeation promotion of the copper-blue peptide is achieved, the layered cool feeling experience which takes effect quickly and is lasting and mild is provided, the common skin irritation problem of a traditional permeation promoter or a high-concentration single freshener is avoided, and the effect is remarkable. And the transdermal patch has excellent transdermal efficiency, active matter stability and use comfort.
Owner:GUANGDONG BAIWEN BIOLOGICAL TECH CO LTD

Medicine for promoting skin injury repair and healing and preparation method thereof

The invention relates to a medicine for promoting skin injury repair and healing and a preparation method thereof, and belongs to the technical field of biological medicines.The medicine is prepared from a radix astragali preparata extract, lipidosome encapsulated panax notoginseng total saponin-RGD peptide, a honeysuckle flower-maca extract, an asiaticoside-hydroxypropyl-beta-cyclodextrin inclusion compound and dipotassium glycyrrhizinate; the radix astragali preparata extract is a product obtained by moistening radix astragali with honey, baking, extracting with deionized water, and adsorbing and purifying with a Sephadex G-15 column; the honeysuckle-maca extract is a product obtained by mixing dry honeysuckle powder and dry maca root powder according to the mass ratio of (3-5): (1-1.7), performing enzymolysis through cellulase, then performing common enzymolysis through ficin protease and papain, and performing adsorption and purification through an HPD722 macroporous adsorption resin column. All the components are compatible according to a specific proportion, so that the allergy and skin irritation risks are reduced, skin injury healing is reasonably promoted, and melanin deposition is effectively inhibited.
Owner:HUBEI SUIZHOU SHUANGXING BIOLOGICAL SCI & TECH CO L

Sulfate-free silicone-oil-free solid shampoo soap and preparation method thereof

PendingCN121227438AHair cosmeticsDetergent dyesGuar hydroxypropyltrimonium chlorideChemical products
The invention belongs to the field of daily chemical products, and particularly relates to sulfate-free silicone-oil-free solid shampoo soap and a preparation method thereof. The solid shampoo soap comprises sodium cocoyl isethionate, sodium methyl cocoyl taurate and / or cocamidopropyl betaine, cetostearyl alcohol, behentrimethylammonium chloride, guar hydroxypropyltrimethylammonium chloride, quaternary ammonium salt-80, glycol distearate, synthetic grease, natural grease, glycerin, a humectant, a plant extract, a chelating agent and a preservative. A pH regulator, essence and pigment; the solid shampoo soap provided by the invention adopts mild and non-irritant components, avoids irritation of sulfate surfactants to skin, can effectively reduce the problems of dry skin, allergy and the like, and provides healthier and more comfortable cleaning experience for consumers due to the fact that no silicone oil is used for reducing blocking of hair follicles.
Owner:HUIZHOU ZHAOTING COSMETIC

High-efficiency mild unhairing cosmetic and preparation method thereof

The invention relates to the technical field of cosmetics, and discloses a high-efficiency mild depilation cosmetic and a preparation method thereof, and the raw materials of the depilation cosmetic comprise, by weight, 8-10% of bromelain; 10%-12% of a turmeric root extract; 9%-11% of a calendula extract; 6%-9% of an aloe extract; 4%-7% of a soybean extract; 7%-10% of calcium thioglycolate; 2%-5% of L-cysteine; 1%-3% of sodium bicarbonate; 3%-6% of green tea polyphenol; 2%-4% of a chamomile extract; 1%-3% of dipotassium glycyrrhizinate; 0.9%-2.3% of a peptide component; 0.5%-1% of rosmarinic acid; 1%-3% of vitamin E; 2%-4% of gluconic acid; 4%-5% of beewax; 5%-10% of an emulsifier; according to the invention, dipotassium glycyrrhizinate and the chamomile extract form a dual anti-allergy barrier, the physical protection effect of aloe polysaccharide is combined to reduce skin irritation, and the turmeric root extract and the peptide component prolong the hair follicle resting period and reduce the hair regeneration rate, so that the safer and more effective hair removal cosmetic is prepared.
Owner:GUANGZHOU YUNMEI COSMETICS CO LTD

A method for preparing a ceramide cell phospholipid composition by complex coacervation and its application

The present invention provides a method for preparing a ceramide cell phospholipid composition by complex coacervation and its application, belonging to the technical field of cosmetics. It solves the technical problems such as low preparation efficiency, high production energy consumption, poor preservation effect, poor moisturizing and whitening and anti-wrinkle effects of existing cosmetics. The formula of the ceramide cell phospholipid composition prepared by complex coacervation in the present invention is reasonable, with a high ceramide content, good product quality, can be stored for a long time, has the effects of promoting the absorption of active substances and reducing skin irritation, can significantly increase the water content of the skin, has a stable and lasting moisturizing effect, has soothing and repairing effects, and enhances the whitening and anti-aging effects; the method for preparing the ceramide cell phospholipid composition by complex coacervation in the present invention is produced by a combined device, and the hot cycle and pipeline production are adopted to ensure the mixing reaction effect, with high preparation efficiency, short production time and low energy consumption.
Owner:WUSHUANG THEONE

Cosmetic material and method for producing cosmetic material

Provided is a cosmetic containing ascorbic acid and / or a salt thereof, which has excellent stability and reduced irritation to the skin. The cosmetic according to the present invention contains ascorbic acid and / or a salt thereof, ultrapure water, and an antioxidant, and the salt of ascorbic acid is at least one selected from the group consisting of a trimethylamine salt, a triethylamine salt, a monoethanolamine salt, a triethanolamine salt, a pyridinium salt, an arginine salt, an ammonium salt, a sodium salt, a potassium salt, a calcium salt, a magnesium salt, and an aluminum salt of ascorbic acid. The antioxidant is glutathione or sodium pyrosulfite, the pH of the cosmetic material is adjusted to 5.0-7.0, and the dissolved oxygen content of the cosmetic material is 0-5 mg / L.
Owner:PRIMALL COSMETICS CO LTD

Composition for improving skin itch or calming skin

The present invention relates to a composition for improving skin, which comprises beta-sitosterol and betulin and, in the case of the composition, reduces dermatoneuropathic stimulation-inducing factors, increases the expression of moisturizing-related factors, increases skin absorbance, improves skin penetration, inhibits mast cell activity, and improves skin quality. Thus, it has been confirmed that the composition has excellent skin-calming and skin-irritation-relieving effects, and thus can be usefully used in skin-improving cosmetics, pharmaceuticals, and the like.
Owner:LG HOUSEHOLD & HEALTH CARE LTD

A zinc gluconate ointment and a method for preparing the same

The present application relates to the field of external ointment preparation, and provides a zinc gluconate ointment and a preparation method thereof.The ointment comprises, by mass fraction: 0.3-2.0 parts of zinc gluconate, 0.05-1.5 parts of L-histidine, 0.05-1.0 parts of polysaccharide, and the balance of purified water, wherein the polysaccharide is chitosan oligosaccharide or hyaluronic acid oligomer.The zinc gluconate, L-histidine and polysaccharide are dispersed to form hydrogel microdroplets under the condition of pH 5.0-6.0, and are further dispersed in the continuous phase of the oil phase.By establishing a complex system in a weak acid environment and using a double constraint structure of microdroplet dispersion and oil phase, the free Zn 2+ The initial release rate is reduced, skin irritation caused by the initial release of traditional preparations is avoided, and a high 24-hour cumulative release amount is maintained.The ointment exhibits excellent physical stability and particle size uniformity during storage, avoids oil-water layering and crystallization, and has both sustained release and good use feeling.
Owner:HUBEI HUQUAN PHARMA IND

Lignan as well as preparation method and application thereof

The invention provides lignan, and belongs to the technical field of medicines. According to the invention, a compound shown as a formula I and a compound shown as a formula II are extracted, separated and identified from schisandra chinensis oil for the first time, and the compound shown as the formula I and the compound shown as the formula II are superior to a positive drug group arbutin in the aspect of inhibiting generation of melanin of mouse skin melanoma cells (B16F10); an inflammatory factor release inhibition experiment research shows that the compound shown in the formula I and the compound shown in the formula II have relatively good activity in the aspect of inhibiting LPS-induced mouse mononuclear macrophage RAW264.7 from releasing IL-6 and TNF-alpha; in a skin irritation experiment, the schisandra chinensis non-saponifiable matter containing the compound shown in the formula I and the compound shown in the formula II is non-irritant to the skin of a white rabbit, and it is proved that the compound shown in the formula I and the compound shown in the formula II can be applied to preparation of whitening and anti-inflammatory products. Formula I; formula II.
Owner:CHANGSHA DAISY BIOTECHNOLOGY CO LTD

Composite bath product containing lincomycin and vitamin B6 and preparation method thereof

The invention relates to a compound bath product containing lincomycin and vitamin B6 and a preparation method of the compound bath product, and relates to the technical field of daily chemical products. Aiming at the problems of single effect, low component residence rate, poor medical component adaptability and the like of a traditional bath product in acne care, a triple synergistic formula of lincomycin (antibacterial), vitamin B6 (oil control) and glycyrrhizic acid / glycosylglycerol (anti-inflammatory) is innovatively constructed, and the adjuvant therapy effect on mild acne is effectively improved through clinical verification; a pH / temperature dual-response microcapsule wrapping technology is developed, so that the transdermal absorption rate of active ingredients is effectively improved, and the washing loss rate is less than or equal to 15%; the traditional Chinese medicine composition breaks through the limitation of medical cream types, is matched with bath carriers such as facial cleanser, shampoo, soap, shower gel and the like, and realizes daily application of acne care components. The product disclosed by the invention has the advantages of controlling oil within 6 hours and reducing the skin irritation by 42%, and fills up the technical blank of washing and caring products in medicine-grade efficacy and use convenience.
Owner:钟志超

Cardiac and cerebral oil and preparation method thereof

The invention belongs to the technical field of cardio-cerebral oil preparation, and provides cardio-cerebral oil and a preparation method thereof. The invention aims to solve the technical problems that kapur is easy to volatilize and short in efficacy, and skin irritation is easily caused by high-concentration addition. The preparation method comprises the following steps: firstly, wrapping menthol in a molecular cavity of beta-cyclodextrin through a molecular inclusion technology to prepare a molecular capsule capable of effectively delaying volatilization and reducing irritation; secondly, preparing a bionic repair emulsion from various bionic lipids such as ceramide, cholesterol and fatty acid through an emulsification process, and taking the bionic repair emulsion as a core delivery carrier; meanwhile, components such as vanillyl derivatives are compounded to prepare a temperature-sensitive compound; the preparation method comprises the following steps: uniformly dispersing independent kapur, the molecular capsule and the temperature-sensitive compound into the bionic repair emulsion, and curing to obtain a finished product. Through molecular inclusion and the bionic repair emulsion, long-acting release of the effect of the kapur is realized, and the skin irritation of the product is reduced.
Owner:JIANGXI ZHANGXIANG NATURAL ICE SHEET CO LTD

Filtering device for cleaning agent production

The utility model relates to the technical field of cleaning agent production, and discloses a filtering device for cleaning agent production, which comprises a first filtering box, and one end of the top of the first filtering box is fixedly connected with a feeding pipe. According to the filtering device for cleaning agent production, a user enables an external water source to flow into a first filtering box through a first top cover, then a first motor is started to stir materials in the first filtering box, and a first containing frame is installed in a first base; a water source flowing in through a first top cover is filtered by a filter element installed in a first containing frame, impurities and suspended particles in water are removed, poor water quality may affect the quality stability of the cleaning agent after production, cause secondary pollution of the product, reduce the cleaning effect of the cleaning agent and even cause skin irritation or allergy and other reactions of a user, and the cleaning effect is poor. A water source flowing into the first filter box is filtered through the filter element, so that the quality and the safety of a final product are improved.
Owner:CHANGXING JINGAN ENVIRONMENTAL PROTECTION TECH CO LTD

Mud mask containing corn stigma extract and having effects of repairing, resisting wrinkles and removing freckles and preparation method of mud mask

The invention provides a corn stigma extract-containing mask mud with repairing, anti-wrinkle and freckle-removing effects and a preparation method thereof, and relates to the technical field of cosmetics. The mask mud is prepared from the following raw materials: corn stigma extract, guava fruit extract, white willow bark extract, tamarix chinensis flower extract, sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium and auxiliary materials. The corn stigma extract is taken as a main raw material, and the three natural extracts, namely the guava fruit extract, the white willow bark extract and the tamarix chinensis flower extract, are compounded according to a specific proportion, so that multiple effects of resisting wrinkles, removing acnes, whitening, resisting allergy, repairing, removing freckles, tightening, moisturizing, soothing and the like are realized at the same time, and the effect of the corn stigma extract is remarkably improved; sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium is used as a surfactant, so that the lotion is milder and more moisturizing, no preservative is added, and damages such as skin irritation, allergy, red and swollen skin, cuticle damage and dry skin are reduced.
Owner:YUNONGYUAN FOOD CO LTD