36 results about "Biological simulation" patented technology

The invention belongs to the technical field of biological simulation, and discloses an anus cleaning effect evaluation method and system.The method comprises the steps that an execution assembly is controlled to wipe an anus anatomical structure with a to-be-detected sample according to a target wiping strategy, and a multi-mode sensing assembly is controlled to collect target parameters on the anus anatomical structure; obtaining target monitoring data; according to the residual dirt amount in the target monitoring data, a cleaning efficiency score is obtained through calculation, a target mechanical simulation model is called, according to the humidity permeation gradient value and the pressure value in the target monitoring data and the to-be-detected sample, a skin stimulation risk score is obtained through calculation, and the skin stimulation risk score and the cleaning efficiency score form a cleaning effect evaluation report. Simulation and prediction of the anus cleaning process are achieved, the simulation test effect and accuracy are greatly improved, and a cleaning effect evaluation report is given to illustrate the safety of the to-be-tested sample.

The invention provides an automatic construction method and system of an active polypeptide, and the method comprises the following steps: firstly, determining a target metabolite, and obtaining a target protein having binding activity with the target metabolite; then, obtaining interaction information of the target protein and the target metabolite and secondary structure information of target protein residues; then, inputting the interaction information into a large language model LLM to obtain information of key residues of the target protein; and finally, inputting the structural information of the target protein, the information of the key residues, the secondary structural information and the constraint information into LLM to obtain an active polypeptide capable of being specifically combined with the target metabolite, namely the potential peptide aptamer. According to the method, by combining a biological simulation tool and a large language model, automatic batch generation of the active polypeptide is realized, the acquisition process of the polypeptide is greatly simplified, and a new strategy and a new way are provided for metabolite peptide aptamer design.

The invention discloses an interactive humanoid robot expression simulation method based on artificial intelligence, and relates to the technical field of expression simulation, and the method comprises the steps: collecting a brain wave signal of a user, carrying out the preprocessing, and generating a power spectrum density feature; inputting the power spectral density features into a pre-trained emotion classification model, and outputting an emotion category and an emotion intensity value of the user; performing emotional expression mapping on the emotional category and the emotional intensity value, and outputting a bionic muscle contraction instruction; performing facial adjustment on facial muscle fibers of the humanoid robot according to the bionic muscle contraction instruction, dynamically adjusting surface texture details of the humanoid robot, and generating a simulated micro expression; and capturing user face feedback data through camera shooting eyeballs, evaluating the acceptance degree of the user on the simulated micro-expression based on the user face feedback data, and outputting an expression optimization strategy. According to the method, through deformation matching and expression optimization double-closed-loop modeling driven by user feedback, biological simulation of micro-expressions of the humanoid robot is realized.

The invention relates to the technical field of simulation laboratories, and discloses a multifunctional laboratory capable of simulating different marine environments based on ship body carrying, which comprises a ship body capable of simulating different marine environments and manufacturing various controllable flow fields from laminar flow to turbulent flow in an experiment cabin through a controllable flow field generation unit; through the controllable wave generation unit, waves with specified wave heights and periods can be generated in the experiment module; the water body temperature and salinity regulation and control unit is used for quickly and accurately regulating the temperature and salinity of the water body in the experiment module; water bodies with different turbidity and eutrophication levels are simulated through the environmental biological simulation unit; through an outside-in test mode, a sealing door at the bottom of the experiment module is opened, the underwater robot and other equipment are allowed to freely enter and exit, the dynamic response and control algorithm of the underwater robot when entering a complex environment (external real ocean) from a calm environment (in the experiment module) can be tested, and in-situ storage of a sampled sample can be realized.

The invention belongs to the technical field of biological simulation, and relates to an analogue simulation method based on gait control data and related equipment thereof. Carrying out reinforcement learning on the gait simulation agent to obtain the gait simulation agent after reinforcement learning is completed and gait simulation continuous actions output by the gait simulation agent after reinforcement learning is completed; gait control data of the target object are collected; inputting the gait simulation intelligent body into the gait simulation intelligent body after reinforcement learning is completed, and obtaining a walking simulation continuous action corresponding to the target object; through comparison, identifying differential actions; and performing gait adjustment according to the gait control data corresponding to the differential actions. The method is applied to a medical biological simulation science and technology product optimization scene, product stress support adjustment can be carried out in combination with reinforcement learning and analogue simulation modes for an intelligent artificial limb user or an intelligent walking stick user, and a better product experience service is provided for related patients.

The invention relates to the technical field of biological medicine research and development, and discloses an intelligent research and development platform, system and method for network medicine of intelligent medicine. According to the method, an AI analysis module is utilized to construct a dynamic syndrome biological characteristic network based on clinical time sequence data; in combination with a time sequence dynamic syndrome biological simulation body, an evolutionary algorithm is executed through a data processing and control unit, and time sequence application and real-time monitoring are carried out on candidate network drug formulas. And the system evaluates the goodness of fit between a biological state path generated by each formula on the simulation body and an ideal recovery path based on a preset time sequence fitness function, and performs iterative evolution on a formula population through operations such as selection, crossover and variation until an optimal dynamic administration scheme is found. According to the method, the problem of network drug sequential optimization design is solved, an automatic closed-loop research and development system from data modeling to physical verification is constructed, and the efficiency and accuracy of drug research and development are improved.

The utility model relates to the technical field of toys, in particular to a biological simulation stuffed toy, and aims to solve the problem that an existing swing arm type device lacks protection measures, the biological simulation stuffed toy comprises a main body, the main body comprises a main shell, a machine core and a swing arm, the machine core drives the swing arm to swing to simulate the biological swing arm form, and a protection structure is arranged outside the main body. The protection structure is arranged outside the main body in a sleeving mode, the main body is provided with a connecting groove for fixing the protection structure, the protection structure slows down impact force formed by the swinging mechanical structure to a certain degree, and compared with a traditional swing arm toy, the swing arm toy is high in safety, suitable for young children and pets to play and good in development prospect.

The invention discloses a dummy head injury testing device and method for an impact test, the testing device comprises a head assembly, the head assembly comprises a skull, brain tissue, head skin and a sensing device, eye sockets are arranged on the skull, and bionic eyeballs are arranged at the eye sockets; the brain tissue comprises bionic brain tissue and bionic cerebrospinal fluid; the head skin comprises a head skin body and flexible sensing skin arranged on the outer surface of the head skin body, the flexible sensing skin comprises a flexible substrate layer, wire electrodes arranged on the two end faces of the flexible substrate layer respectively and insulating layers covering the wire electrodes, and a plurality of wire electrodes are arranged on the two end faces at intervals. The wire electrodes on the two end faces are orthogonally arranged to form an array structure, and raw materials of the flexible substrate layer comprise silicone rubber and a conductive material. The testing device is good in biological simulation degree, the testing result is closer to the real situation, multiple sensor configuration schemes are provided, and more head injury data can be obtained.

A biological simulation system device (1) is provided with: a container (2) in which a plurality of functional units (6a-6d) are exchangeably accommodated; and a flow path member (3) that is disposed on the front side of the container (2) and that partitions at least a portion of flow paths (33a, 33b) that communicate the plurality of functional units (6a-6d) housed in the container (2).

The invention discloses a building design method and system based on multi-objective optimization, and the method comprises the following steps: determining multi-objective optimization indexes of building design, the multi-objective optimization indexes including a human factor suitability index, a resource circulation efficiency index and a culture suitability index; quantitative data is obtained by adopting a meta-universe rehearsal technology for the human factor suitability index, quantitative data is obtained by adopting a biological simulation algorithm for the resource circulation efficiency index, and quantitative data is obtained by adopting a block chain technology for the culture suitability index; and inputting the quantized data into a multi-objective optimization algorithm, and carrying out collaborative optimization calculation to obtain building design optimization parameters, thereby breaking through the single-objective limitation of energy conservation, cost and space of traditional building design, bringing human factor suitability, resource circulation efficiency and culture suitability into a multi-objective optimization system, and realizing collaborative optimization of humanity + green + culture.

The invention relates to the technical field of visual perception, discloses a biologically inspired collision detection system and robot for atopic impending perception recognition, and constructs a brand-new collision detection model for atopic impending perception recognition. According to the technical scheme, through a six-layer structure (P-> E / I-> A-> S-> G-> LGMD), exponential attenuation, nonlinear modulation and a spatial clustering mechanism are combined, and accurate distinguishing and real-time collision early warning functions of approaching and leaving motion states are jointly achieved from the three aspects of structure, function and biological simulation; the method has the advantages of high direction selectivity, high robustness and low power consumption calculation efficiency, and is particularly suitable for rapid motion sensing tasks in embedded robots and low-calculation-power visual platforms.

The utility model discloses a simulation model for vascular sheath stripping and ligation suture, and relates to the technical field of medical models. The device comprises a second blood vessel, the outer wall of the second blood vessel is communicated with a first blood vessel, the outer walls of the first blood vessel and the second blood vessel are fixedly wrapped with blood vessel tunica vaginalis, the inner walls, close to each other, of the second blood vessel and the first blood vessel are fixedly connected with the same lymph node, and the second blood vessel and the first blood vessel are in a Y shape and are provided with the blood vessel tunica vaginalis on the surfaces. And the lymph node is connected between the second blood vessel and the first blood vessel, so that the tissue structure simulates a real lung structure. The second blood vessel and the first blood vessel are Y-shaped, the blood vessel tunica vaginalis is arranged on the surfaces of the second blood vessel and the first blood vessel, and the lymph node is fixedly connected between the first blood vessel and the second blood vessel, so that a real lung structure can be well simulated, and the blood vessel tunica vaginalis, the first blood vessel and the second blood vessel are made of biological simulation materials with conductive properties and have real touch feeling; therefore, real skill operation can be carried out.

The utility model discloses a dummy head structure calibration device for an automobile crash test, and the device comprises a pendulum bob suspension system which comprises an impact pendulum bob and a hanging rope, and the lower end of the hanging rope is connected with the impact pendulum bob; the air bag impact head is arranged on the impact pendulum bob; the installation structure is placed on the horizontal plane and used for installing the dummy head structure, the dummy head structure comprises a neck and a head arranged above the neck, and when the impact pendulum bob is in the free falling state, the air bag impact head is located on the side, facing the head, of the impact pendulum bob and is opposite to the head. Compared with the prior art, the dummy head structure calibration device for the automobile crash test is more suitable for a crash contact mode in an actual automobile crash test, the biological simulation degree of the dummy head structure can be more fully verified, the accuracy of evaluating the injury of the dummy head structure in the automobile crash test is improved, and the dummy head structure calibration device for the automobile crash test is more suitable for popularization and application. And the validity of automobile collision test data is ensured.

The invention relates to the technical field of VR training, in particular to a VR-based nursing training system which comprises a central processing module, a virtual environment modeling module, a pain sense quantification module, a nursing resistance simulation module, an OpenPose posture recognition module and a VR component. The care resistance simulation module constructs a care resistance action set, when a user operation error occurs, the pain quantification module generates a pain index according to the human body pain sensitivity map set and scene and interaction data, the pain index is transmitted to the care resistance simulation module, and when the pain index is transmitted, the care resistance simulation module gives an alarm. The nursing resistance simulation module randomly selects the corresponding nursing resistance action from the nursing resistance action set, and by organically combining the VR technology, the biological simulation technology and the medical evaluation, the user is helped to learn how to correctly nurse the cognitive impairment patient with the nursing resistance behavior.

The invention relates to the technical field of bionic robots, and provides a bionic robot monkey which comprises a simulation body, a sensing detection assembly, a simulation assembly and a control system. The sensing detection assembly is used for collecting feature information of a natural monkey, and the control system is used for obtaining the feature information, sending the feature information to the terminal device, receiving a posture adjustment instruction from the terminal device, controlling the simulation body to adjust the posture to a target posture, and receiving a simulation stimulation instruction from the terminal device. And controlling the simulation component to output the biological simulation information. The bionic machine monkey disclosed by the invention can simulate a natural monkey to the greatest extent, can be hidden in a natural monkey group, can stimulate the natural monkey and observe the stress response of the natural monkey while acquiring the characteristic information of the natural monkey, and can be used as a limb driven recarving device of an experimenter to realize interaction and behavior guidance with the natural monkey; and the information interaction between experimenters and the natural monkeys is well assisted.

The application belongs to the technical field of biological simulation, and discloses a method and system for evaluating the cleaning effect of an anus. The method controls an execution assembly to wipe the anus anatomical structure according to a target wiping strategy, and controls a multi-modal sensing assembly to collect target parameters on the anus anatomical structure to obtain target monitoring data. According to the residual dirt amount in the target monitoring data, a cleaning efficiency score is calculated, and a target mechanical simulation model is called to calculate a skin irritation risk score according to the humidity penetration gradient value and the pressure value in the target monitoring data and the test sample, so as to form a cleaning effect evaluation report with the cleaning efficiency score, thereby realizing simulation and prediction of the anus cleaning process, greatly improving the simulation test effect and accuracy, and providing the cleaning effect evaluation report to indicate the safety of the test sample.

The invention relates to a protein-ligand binding affinity prediction method, system, equipment and medium, and relates to the technical field of biological simulation prediction.The method comprises the steps that a protein-ligand binding affinity data set is collected and comprises a protein sequence and a ligand SMILES sequence; extracting global features and local features of the protein sequence and the ligand SMILES sequence; respectively performing feature enhancement on the global features and the local features of the protein sequence and the ligand SMILES sequence to obtain the global features and the local features of the enhanced protein sequence and the ligand SMILES sequence; performing feature fusion on global features and local features of the enhanced protein sequence and the ligand SMILES sequence to obtain fused features; and performing feature prediction on the fused features to obtain the value of the protein-ligand binding affinity. According to the method, the value of the protein-ligand binding affinity can be effectively predicted.

The invention discloses a human body biological lung positive pressure ventilation simulation device and method.The device comprises a biological simulation lung, a three-way connector, an air pressure throttling pipe, an air blower, a vacuum pump, a pressure sensor, a controller and an upper computer, and three connectors of the three-way connector are connected with the biological simulation lung, the air pressure throttling pipe and an air extraction opening of the vacuum pump respectively; an air outlet of the air blower is connected with the air pressure throttling pipe, a plurality of throttling holes are formed in the air pressure throttling pipe and located in the same circumferential face, two detection pipes are led out of the air pressure throttling pipe, air inlets of the two detection pipes are located in the upstream side and the downstream side of the throttling holes, and a pressure sensor is arranged at an air outlet of each detection pipe. The pressure sensor is connected with the controller, and the controller is connected with the upper computer.

The present application relates to the technical field of biological simulation experiment, and particularly relates to a ruminant in-vitro digestion system; comprising: a partitioned case platform and a bionic digestion reaction module, a dry heat field control module, a precise fluid and gas path distribution module, and a central control module; the present application constructs a dry infrared radiation coupling three-dimensional turbulent heat field, discards the water bath heating mode of high humidity corrosion, fundamentally eliminates the risk of electrochemical corrosion of the precise sensor interface, realizes the millisecond-level temperature control response superior to the water bath, and the system can autonomously execute the pH steady-state regulation of simulated saliva secretion and the pressure metabolic control of simulated belching, thereby constructing an intelligent experimental platform of highly reduced ruminant rumen physiological function in an absolute anaerobic closed system.

The utility model discloses a safety test dummy neck assembly and a safety test dummy, and relates to the technical field of automobile crash safety test, the neck assembly is connected between the head and the upper trunk of the safety test dummy, the neck assembly comprises an upper connecting body, an elastic deformation body and a lower connecting body, the upper connecting body is connected with the head, the elastic deformation body is connected with the lower connecting body, and the elastic deformation body is connected with the lower connecting body. The lower connecting body is connected with the upper trunk, and the elastic deformation body is connected between the upper connecting body and the lower connecting body; wherein the elastic deformation body comprises a main body part and an elastic gradual change part, the two ends of the main body part are connected with the upper connecting body and the lower connecting body respectively, the elastic gradual change part is located on the front side of the main body part, and the elastic modulus of the elastic gradual change part is smaller than that of the main body part. According to the neck assembly of the safety test dummy, the elastic gradual change part is arranged, so that the safety test dummy simulates the motion state of a human body when the human body is collided, and the biological simulation degree and the test data precision of the safety test dummy are improved.

A system (200) and a method for generating a digital human (400) for a virtual environment. The method (100) includes capturing motion of a human body (300) through multiple inputs associated with the human body (300) and generating a motion capture file which includes multiple marker positions (302) associated with the motion of the human body (300). Further, the method includes determining a physical simulation and a biological simulation for the digital human (504, 604) using the motion capture file and superimposing the physical simulation and the biological simulation on the digital human (504, 604) corresponding to the human body (300). Finally, the method includes displaying the digital human (504, 604) in the virtual environment.

The present invention discloses an endogenous heat measurement method based on infrared skin temperature distribution field, comprising the following steps: S1. establishing a finite element model; S2. using the finite element analysis method to simulate the relationship between the position, temperature, and thermophysical parameters of the internal heat source and the body surface temperature distribution; S3. burying the developed constant temperature adjustable heat source in a uniform layered biological tissue, using a human body temperature measurement infrared thermal imager to capture the temperature of the tissue surface and each layer of tissue, and analyzing the distribution of the surface and internal temperature fields. The present invention simulates human skin through a biological simulation body, captures the skin temperature of the biological simulation body through a medical infrared thermal imager, and transmits data through the establishment of a data transmission system to form a temperature distribution infrared thermal map, which can provide a basis for diagnosing abnormal heat sources in the body. Finally, through simulation and analysis, it can provide a theoretical basis and guiding significance for the study of the formation mechanism of human body surface temperature distribution characteristics and the inverse problem of heat sources.

The invention provides a large-scale biological cluster simulation method in a live-action three-dimensional model based on oblique photography, and the method comprises the steps: constructing a live-action three-dimensional scene, carrying out the ground object separation, taking the separated movable object and crowd as fluid, and carrying out the volume discretization of the fluid into particles with physical attributes according to the volume, thereby achieving the simulation of the large-scale biological cluster in the live-action three-dimensional model. And acquiring a fluid force field, endowing the immobile model and the individual with different motion postures according to particle force field information in fluid force field information, planning a global path of a group, and selecting different local driving strategies to carry out real-time dynamic microscopic correction on the advancing direction of the individual on the advancing path so as to realize large-scale cluster biological simulation. According to the invention, multiple types of fluids are bidirectionally fused, so that each individual can still keep independent main power under the influence of a group, and the diversity of the individuals is kept.

The invention discloses a three-dimensional dynamic biological simulation method based on formulation modeling, which comprises the following steps of: initializing a three-dimensional simulation space and initial position, speed and morphological parameters of an organism to construct a parameterized biological morphological model; dynamically updating the two-dimensional form reference of the organism and the position and posture of the organism in the three-dimensional space based on the form modulation parameters and the movement speed; the method comprises the following steps of: converting a two-dimensional form into a three-dimensional entity structure with symmetry or randomness by adopting a differentiation strategy such as equal-angle slicing or random direction generation aiming at different structure parts of a living body, and performing linear interpolation to enhance continuity; and finally, rendering the three-dimensional entity structure into volume data, performing superposition intensity projection along a preset direction, generating continuous frame images, and outputting multi-page TIFF format simulation data after a preset frame number is reached.

The invention discloses a radiation refrigeration mycelium material with a biological simulation elephant skin structure and a preparation method of the radiation refrigeration mycelium material, and belongs to the technical field of functional composite materials and green energy. The radiation refrigeration mycelium composite material is prepared by taking biological simulation mycelium as a substrate and loading double-layer nano-scale particles of a silicon dioxide layer and a PTFE layer, so that the problems that an existing radiation refrigeration material is low in radiation efficiency, a loading coating is easy to fall off, the environmental friendliness is poor and the like are solved.

A chip of the heart pace-making device adopts a BCD process, and the heart pace-making device comprises a data acquisition module used for acquiring biological simulation signals of a human body in real time; the data preprocessing module is used for converting the collected biological analog signal into a biological digital signal; the first machine learning module outputs a decision signal based on the input biological digital signal; and the digital control module is used for converting the decision signal into a digital control signal so as to execute the treatment action of the cardiac pacing device. The BCD process can realize analog and digital mixed signal functions on a single chip, and has the characteristics of low power consumption and high performance. Biological simulation signals of a human body are collected in real time through the data collection module, and working parameters of the cardiac pacing device are dynamically adjusted according to individual differences and physiological states of patients. The first machine learning module can output a decision signal based on the input biological digital signal, and the working state of the cardiac pacing device can be intelligently adjusted through the first machine learning module adopting an artificial intelligence algorithm.

We provide the system. [Solution] This invention relates to a drug discovery support system that integrates diverse data such as scientific papers, clinical trials, patient records, and genetic information, and autonomously and rapidly performs tasks such as extracting therapeutic targets for each disease, designing novel compounds, virtual biological simulations, toxicity and efficacy evaluations, optimization proposals, and automatic report generation using generative AI. This significantly shortens the entire drug discovery process, which previously took a long time, and enables efficient and highly accurate responses to diverse medical needs, such as rare diseases and intractable diseases, thereby improving the success rate of drug discovery and maximizing social value.

The invention belongs to the technical field of biomimetic agent release devices, and particularly relates to a preset remote biomimetic agent release device which comprises a shell, a biomimetic agent box, an annular air duct, a spraying device, a generating device, a blower device, a remote control system and a power supply system. The biological simulation agent in the biological simulation agent box is primarily atomized through the generating device, then the primarily atomized biological simulation agent is mixed with air flow driven by the blower device in the annular air duct to complete secondary atomization, and then the biological simulation agent aerosol with more concentrated and more stable particle size distribution is formed after the biological simulation agent aerosol is sprayed out through the spraying device. The process realizes the remote release of the biomimetic agent, effectively increases the propagation range of the biomimetic agent, and realizes the control of the generation concentration at the same time.

A system for treaty-governed genomic compilation and secure biological synthesis that regulates the translation of digital genetic information into physical matter. The apparatus comprises a Symbolic Verification Kernel configured to deconstruct target nucleic acid sequences into functional semantic representations and execute predictive biological simulations to assess toxicity and dual-use risk against an immutable Treaty Ledger. Physical synthesis is controlled by a hardware-locked DNA synthesis apparatus that remains mechanically disabled until it receives and validates a cryptographically signed Sovereign Synthesis Token issued by the kernel. The system further includes a Bio-Encryption Engine that interleaves non-coding watermarks into the synthesized material, establishing a permanent, molecular-level chain of custody for all fabricated genetic content. The architecture thereby enforces international biological safety constraints directly at the point of manufacture, preventing the unauthorized synthesis of pathogenic or restricted biological agents.

The invention discloses an examination anxiety detection method and device based on acupoint bio-electricity signals. The method comprises the following steps that an acupoint signal acquisition end is arranged on the acupoint surface of a user; the method comprises the following steps: collecting biological simulation signals of multiple acupuncture points through an acupuncture point signal collection end, and processing according to the multiple biological simulation signals to obtain multiple biological digital signals; obtaining a weight scale factor corresponding to each acupoint from a database, and processing the plurality of biological digital signals in combination with the weight scale factor of each acupoint to obtain an examination anxiety state value; an examination anxiety threshold value is obtained from the channel and acupoint examination anxiety database, the examination anxiety state value and the examination anxiety threshold value are compared, and an examination anxiety detection result is obtained and output; if the test anxiety state value is larger than or equal to the severe test anxiety threshold value, a test anxiety reminding signal is sent out. Whether examination anxiety exists or not and the examination anxiety state are judged by detecting changes of the acupuncture point electric signals of the human body, and the method is more scientific, accurate and efficient.