123 results about "Right heart" patented technology

A catheter includes a catheter body, a pump assembly and a cannula. The pump assembly can be disposed at a distal end of the catheter body and has a distal portion. The cannula can be coupled to the distal end portion of the pump assembly and can include a proximal cannula portion and a distal cannula portion. The distal cannula portion has an approximately helical shape which can allow the cannula to be inserted into a patient's right heart and pump blood therethrough. In certain implementations, the distal tip of the helical shape has a slight bias relative to the main helix to further facilitate delivery of the device. In certain applications this bias is toward the central axis of the helix.

The invention discloses a device and method for accurately adjusting the extracorporeal circulation left and right heart compression degree, and relates to the technical field of medical instruments. The device for accurately adjusting the extracorporeal circulation left and right heart compression degree comprises a first connector, a sterile saline bag, a first pipeline, a first flow stopping piece, a second connector and a second pipeline. The first connector is suitable for being installed on a liquid inlet pipeline of the rolling pump. The liquid outlet end of the sterile saline bag is connected with the first joint through a first pipeline; the first flow stopping piece is suitable for being arranged on a liquid inlet pipeline of the rolling pump and clamping and closing the blood inlet end of the first connector; the second joint is suitable for being mounted on a liquid outlet pipeline of the rolling pump, and the second joint is detachably connected with the pulmonary membrane through a second pipeline; the second flow stopping piece is suitable for being arranged on a liquid outlet pipeline of the rolling pump and clamping and closing the bleeding end of the second connector. According to the device and the method for accurately adjusting the extracorporeal circulation left and right centroid compaction degree, the accuracy and the convenience of adjustment of the extracorporeal circulation left and right centroid compaction degree are greatly improved.

The invention discloses a method for noninvasive diagnosis of pulmonary arterial hypertension and a related device, and relates to the technical field of artery detection.The method comprises the steps that an echocardiogram result and right heart catheter pulmonary artery pressure data of a suspected pulmonary artery patient are obtained; the echocardiogram result is a tricuspid regurgitation spectrum; grading the quality of the tricuspid regurgitation spectrum based on a TR spectrum quality grading standard according to the regurgitation spectrum missing degree of the tricuspid regurgitation spectrum; according to the echocardiogram result and the right heart duct pulmonary artery pressure data, on the basis of the quality grading result of the tricuspid regurgitation spectrum, a personalized pulmonary artery hypertension diagnosis model suitable for different patients is constructed; according to the pulmonary arterial hypertension diagnosis model, on the basis of the echocardiogram result of the target pulmonary arterial patient, a pulmonary arterial hypertension diagnosis result of the target pulmonary arterial patient is obtained, and personalized accurate diagnosis can be carried out on different pulmonary arterial hypertension patients under the noninvasive condition.

The invention discloses a method for controlling the compaction degree of a left heart and a right heart in an extracorporeal circulation operation, which comprises the following steps of: in an in-vitro environment, mounting a peristaltic pump at a left heart inlet and a right heart inlet of an extracorporeal circulation device; a liquid inlet of the peristaltic pump is connected with a liquid inlet pump, and a liquid outlet of the peristaltic pump is connected with a liquid outlet pump; and finally, a first pressure measuring structure and a second pressure measuring structure are arranged on the sides, away from the peristaltic pump, of the liquid inlet pump and the liquid outlet pump correspondingly, and the pressure of the liquid inlet pump and the pressure of the liquid outlet pump are adjusted to be-20 mmHg. The negative pressure of the liquid inlet pump is adjusted through the first pressure measuring structure, and the negative pressure of the liquid outlet pump is adjusted through the second pressure measuring structure, so that the purpose of quantifying the adjusting mode is achieved, and the adjusting mode is accurate, rapid and high in reliability; the peristaltic pump can effectively avoid the occurrence of risks such as blood component damage, hemolysis, gas embolism and the like caused by reduction of the amount of blood conveyed by the pump, insufficient blood supply or direct interruption of blood circulation due to the condition that a pipe body connected with the peristaltic pump is shrunken or cannot be sucked during an operation.

The invention discloses a method for controlling left and right heart compaction degree before extracorporeal circulation operation, which comprises the following steps of: installing a peristaltic pump at a left and right heart inlet of an extracorporeal circulation device in an in-vitro environment; a liquid inlet of the peristaltic pump is connected with a liquid inlet pump, and a liquid outlet of the peristaltic pump is connected with a liquid outlet pump; and finally, a first pressure measuring structure and a second pressure measuring structure are arranged on the sides, away from the peristaltic pump, of the liquid inlet pump and the liquid outlet pump correspondingly, and the pressure of the liquid inlet pump and the pressure of the liquid outlet pump are adjusted to be-180 mmHg. The negative pressure of the liquid inlet pump is adjusted through the first pressure measuring structure, and the negative pressure of the liquid outlet pump is adjusted through the second pressure measuring structure, so that the purpose of quantifying the adjusting mode is achieved, the adjusting process for controlling the left and right heart compression degree before the extracorporeal circulation operation is visualized, the adjusting result is converted into the specific negative pressure values of the liquid inlet pump and the liquid outlet pump, and the accuracy of the operation is improved. The pressing degree reference for adjusting the left center and the right center is numeralized and standardized, the adjusting difference is avoided, experience and feeling are not needed, and the adjusting mode is fast and high in accuracy.

The invention relates to the field of heart nuclear medicine, in particular to a technical method for carrying out myocardial blood flow quantitative analysis through dynamic SPECT imaging of a boric acid 99mTc labeled single-photon SPECT imaging agent, image processing, image correction and myocardial blood flow quantitative calculation, and the technical method is used for generating a dynamic bull's-eye map and a left heart blood pool time activity curve. The method provided by the invention can be used for correcting right heart blood pool overflow interference and myocardial uptake residue interference, quantifying myocardial blood flow and improving fitting operation efficiency, can also be used for establishing a myocardial blood flow volume diagram, and is applied to more intuitively evaluating the resting blood flow, the load blood flow and the high and low areas of the blood flow reserve of the whole myocardial and blood vessel partition. The method provided by the invention can solve the technical problem of myocardial blood flow quantitative analysis by dynamic SPECT imaging of the boric acid 99mTc labeled single-photon SPECT imaging agent and the application problem of the dynamic SPECT imaging of the boric acid 99mTc labeled single-photon SPECT imaging agent.

The invention discloses an application of a phosphodiesterase inhibitor in preparation of a medicine for preventing and / or treating pulmonary arterial hypertension, and the phosphodiesterase inhibitor is 1-(4-(2, 3-dihydro-1H-indeno [5, 6-b] furan-5 (4H)-keto) piperidine-4-yl)-4-chlorobenzoate. The phosphodiesterase inhibitor disclosed by the invention can effectively reduce pulmonary vascular remodeling caused by abnormal proliferation and migration of pulmonary artery smooth muscle cells, so that pulmonary artery pressure and right ventricular systolic pressure are remarkably reduced. The phosphodiesterase inhibitor disclosed by the invention has a prominent effect on inhibiting pulmonary vascular remodeling and right heart hypertrophy, has the effect of improving various clinical symptoms of pulmonary arterial hypertension, is superior to common pulmonary arterial hypertension treatment medicines at present, and has important significance on finding more new medicines for treating pulmonary arterial hypertension.

The invention discloses a pulmonary arterial hypertension diagnosis and severity degree judgment prediction model based on myocardial magnetic resonance, a construction method and application. Through statistical analysis of myocardial magnetic resonance and test information of a pulmonary hypertension patient and a contrast, specific indexes of the pulmonary hypertension patient are screened out, and new clinical models for pulmonary hypertension diagnosis are respectively constructed. The model comprises five independent predictive variables: ascending aorta width, left atrial anterior-posterior diameter, left ventricular ejection fraction, pulmonary artery width and platelet level; the invention further discloses a pulmonary arterial hypertension severity prediction model. The model comprises two independent prediction variables, namely the left ventricular end diastolic volume index and the body weight. The constructed diagnosis prediction model is based on Lasso regression and Logistic regression technologies, the dependence on traditional invasive right heart catheter examination is effectively reduced, the comfort level of a patient is greatly improved, the diagnosis process is optimized, and the overall diagnosis efficiency is improved.

The invention belongs to the technical field of medicines, and discloses an application of a small molecule compound in preparation of a product for preventing and / or treating pulmonary arterial hypertension and complications thereof. The small molecule compound is 8-[[4-(cyclopropanecarbonyl) piperazine-1-yl] methyl]-1, 3-dimethyl-7-(3-methylbutyl) purine-2, 6-diketone, and the structural formula is as shown in a formula (I): # imgabs0. The small molecule compound and pharmaceutically acceptable salts thereof have a remarkable treatment effect on pulmonary arterial hypertension and complications thereof, and can be used for treating pulmonary arterial hypertension and complications thereof. The effects of preventing and / or treating the pulmonary arterial hypertension include the reduction of right heart hypertrophy, the reduction of right ventricular systolic pressure, right heart enlargement, right heart dysfunction, pulmonary vascular remodeling, pulmonary arterial intima thickness, increase of vascular myelization, pulmonary arterial smooth muscle cell proliferation and migration, the reduction of the right ventricular hypertrophy, the reduction of the right ventricular hypertrophy, the reduction of the right ventricular hypertrophy and the reduction of the right ventricular hypertrophy. The pulmonary arterial intima thickness and the vascular myelization level are improved, pulmonary vascular remodeling is reversed, and pulmonary artery smooth muscle cell proliferation and migration are inhibited.

The invention provides an automatic counting method and system for ultrasonic microbubbles in right heart acoustic radiography. The method comprises the following steps: acquiring a cardiac radiography image of a patient through high-resolution ultrasonic equipment; extracting a region of interest of the cardiac angiography image based on the cardiac vascular structure, and performing image registration operation on the cardiac angiography image by taking the region of interest as a reference point to obtain a registered image; carrying out pixel-by-pixel addition on two frames of pulse images with opposite phases in the registered image to obtain an enhanced image; determining the high-echo bright spots in the enhanced image as suspected microbubbles, and performing denoising processing according to the feature similarity to obtain real microbubbles; judging pathological conditions according to whether real microbubbles exist in the left atrium or not; if the real microbubbles exist in the left atrium, grading the abnormal blood flow according to the change data of the microbubbles in the left atrium and the right atrium. According to the method, through high-precision image registration, multi-modal feature analysis and dynamic parameter fusion technologies, the microbubble detection accuracy is improved, and quantitative grading of pathological conditions is achieved.

The invention discloses a pulmonary arterial hypertension risk prediction model based on night hypoxia and cardiac ultrasound indexes and a construction method thereof, and the method comprises the steps: collecting cardiac ultrasound examination indexes, right cardiac catheter examination data and night sleep respiration monitoring data of a patient with chronic thromboembolic pulmonary diseases; the method comprises the following steps: according to hemodynamic data measured by right heart catheter examination, grouping into a CTEPD accompanied PH (hereinafter referred to as CTEPH) group and a CTEPD non-accompanied PH group, and carrying out statistical analysis on all collected data; risk factors related to the CTEPH are screened out; and screening CTEPH prediction model variables and constructing a pulmonary arterial hypertension risk prediction model. According to the method, the pulmonary arterial hypertension risk prediction model based on the night hypoxia and cardiac ultrasound indexes is constructed, the CTEPH risk is diagnosed only by combining the hypoxia indexes with the cardiac ultrasound indexes, non-invasive risk assessment is achieved, no harm is caused to patients, operation is easy and convenient, the model performance is good, and the method can be popularized and popularized in hospitals at all levels in China and is wide in applicability.

The invention belongs to the technical field of medicines, and discloses application of WZ3146 in preparation of products for preventing and / or treating pulmonary arterial hypertension and complications thereof. The WZ3146 and the pharmaceutically acceptable salt thereof have a remarkable treatment effect on pulmonary arterial hypertension and complications thereof, such as mean pulmonary arterial pressure, high right ventricular systolic pressure, right heart enlargement, right heart dysfunction, pulmonary vascular remodeling, pulmonary arterial intima thickness, increase of vascular myelization, pulmonary artery smooth muscle cell proliferation and migration and the like; the effects of preventing and / or treating pulmonary arterial hypertension comprise expanding the right heart, improving the pulmonary arterial intima thickness and the vascular myelization level, reversing pulmonary vascular remodeling and inhibiting pulmonary artery smooth muscle cell proliferation and migration.

The present invention discloses a method for adjusting the compression degree of the left and right hearts of an extracorporeal circulation device, comprising the following steps: S1: connecting a suction pump to the left and right heart connecting tubes of an extracorporeal circulation device, installing a first joint at the pump inlet of the suction pump, and installing a second joint at the pump outlet of the suction pump; S2: using a first connecting tube to connect a sterile saline bag on the first joint, and using a second connecting tube to connect a membrane lung on the second joint; S3: using a pipe clamp to clamp the first connecting tube and the second connecting tube; S4: measuring the spring sound generated when the pipe clamp clamps the tube body, and the spring sound when the pipe clamp is compressed is 45 decibels-85 decibels, indicating that the compression degree is accurate. Compared with the existing adjustment method, it is simpler and more convenient, and the precision adjustment is more controllable and reliable, which can effectively ensure that the adjustment compression degree is within the precise range, and the adjustment of the compression degree of the left and right hearts can be achieved without relying on personal experience. Both novice operators and experienced operators can quickly master the adjustment operation of the compression degree of the left and right hearts.

The present invention provides a portable guidance device for cardiopulmonary resuscitation, which comprises a tri-axial gravity sensing element, a pressure sensing element, a sound output element, a visual output element and a microcontroller. The portable guidance device for cardiopulmonary resuscitation can actively connect to the medical rescue system and issue an alarm to guide the surrounding passers-by to perform real-time rescue and perform correct cardiopulmonary resuscitation, so as to improve the efficiency and accuracy of chest compressions.

The invention discloses a blood leakage rate measuring device and method and a clinical actual blood flow obtaining method. The blood leakage rate measuring device comprises a right heart simulator filled with liquid and a pulmonary artery simulator, a second pressure sensor and a first pressure sensor are installed at the bottom in the right heart simulator and the pulmonary artery simulator, the right heart simulator is communicated with the pulmonary artery simulator through a first pipeline and a second pipeline, and an auxiliary pump is installed on the first pipeline. The right heart auxiliary catheter penetrates through the right heart simulator, the valve assembly is arranged in liquid in the right heart simulator, the end cap is arranged in liquid in the pulmonary artery simulator, a second flow sensor is installed on the outer wall of the short tube part between the right heart simulator and the pulmonary artery simulator, and a first flow sensor is installed on the outer wall of the long tube part close to the extracorporeal membrane type cavity. According to the clinical actual blood flow obtaining method, the actual blood flow of the right heart auxiliary catheter can be accurately obtained through the obtained blood leakage rate.

The invention belongs to the technical field of medical ultrasonic diagnosis auxiliary equipment, and discloses an electric right heart acoustic radiography foaming device which comprises a device body, the device body comprises a base, a mounting plate is fixedly arranged on the rear side of the base, a driving assembly is arranged on the front side of the mounting plate, and the driving assembly comprises fixing frames fixed to the upper side and the right side of the mounting plate; a stepping motor is fixedly arranged at the top of the fixing frame, a ball screw is fixedly arranged at the tail end of a main shaft of the stepping motor, a sliding block is spirally arranged on the outer side of the ball screw in a sleeving mode, and a connecting rod is fixedly arranged at the bottom of the sliding block, so that accurate controllability of power transmission and visual adjustment of parameters in the contrast agent injection process are achieved; specifically, key parameters such as injection speed and dosage can be accurately set through the operation panel, a traditional manual injection mode is replaced, and the stability of the foaming effect of the contrast agent is guaranteed.

The invention relates to the technical field of medical instruments, in particular to an intelligent catheter implanted right heart blood flow management system, a blood pumping impeller comprises a hub structure and a blade assembly fixed around the hub structure, and the near end of a hub is an annular concave curved surface used for guiding blood flow; the blade assembly comprises two symmetrical continuous blades with the same thickness, and the placement angles of the blades are gradually increased from the near end to the far end. The design structure that the segmented hub and the continuous blades are combined is adopted, all segments of the hub structure have different geometrical characteristics, the molded line of each continuous blade is formed by combining an arc and a straight line, and the design of a gradually-increased setting angle and a large wrap angle is matched with the design of a parabola at the far end of the hub, so that the shear stress and the flow dead zone are reduced, and the service life of the impeller is prolonged. Therefore, the risks of hemolysis and thrombus are reduced, the blood flow path is optimized under the miniaturized condition, the catheter implantation type miniature axial flow blood pump is more suitable for the blood flow flowing characteristic in the catheter implantation type miniature axial flow blood pump, and smooth transition from radial inflow to axial outflow of blood can be achieved.

The invention belongs to the technical field of medical treatment, particularly discloses an application of allicin in preparation of a medicine for improving right heart dysfunction caused by pulmonary arterial hypertension, and discloses an effect of the allicin in treatment of the right heart dysfunction caused by the pulmonary arterial hypertension. Compared with existing medicines (mainly for reducing pulmonary arterial pressure) for treating pulmonary arterial hypertension, allicin not only can reduce the pulmonary arterial pressure and relieve the symptoms of pulmonary arterial hypertension, but also can remarkably improve right heart dysfunction caused by pulmonary arterial hypertension, and the allicin is specifically shown as follows: (a) average pulmonary arterial pressure, pulmonary artery ejection time and pulmonary artery end diastolic inner diameter are reduced; the pulmonary artery acceleration time is prolonged; (b) the right ventricular systolic pressure, the right ventricular end-of-systolic free wall thickness, the right ventricular end-of-systolic free wall thickness, the right ventricular end-of-systolic inner diameter and the right heart hypertrophy index are reduced, and tricuspid valve displacement, stroke output and right heart discharge are increased; and (c) improving right ventricular and pulmonary vascular remodeling.

The invention discloses a pulmonary arterial hypertension recognition device and method based on multiple paths of electrocardio heart sound signals, and relates to the technical field of biomedicine, and the method comprises the steps: limiting an aortic valve closing candidate peak and a drop point of a pulmonary valve closing candidate peak in a time interval between a main peak anchor point time boundary of a double-anchoring split fragment set and an electrocardio fragment key turning point; adjacent beat backtracking replacement and multi-channel consistent voting retention are performed on candidate peaks of cross-beat hopping, and a physiological consistent split fragment set is generated; and according to the physiological consistency split fragment set, converging split sequences of multiple paths of heart sounds, and carrying out beat-level splicing and in-window consistency closing on the split sequences and right heart load related form entries of multiple paths of electrocardio, so as to generate a pulmonary arterial hypertension recognition and diagnosis set. According to the method, high-precision synchronization of multiple paths of electrocardiogram and heart sound signals is realized, equipment difference and noise interference are eliminated, the reliability of feature extraction is guaranteed, and the pulmonary arterial hypertension recognition stability is improved.

The foldable blood pump for right heart assistance is small in intervention size, large in flow and small in blood damage and comprises an expandable and contractible pumping assembly, the near end of the pumping assembly is connected with an in-vitro driving unit through a flexible transmission unit, the pumping assembly comprises a foldable impeller and an expandable shell arranged on the periphery of the foldable impeller in a covering mode, and the expandable shell is connected with the foldable impeller. The thin film extends from the middle section of the expandable shell to the far side and extends to the catheter outside the expandable shell, the near section of the expandable shell forms a blood inflow port, and a blood outflow port is formed in the far end of the thin film. The impeller is of a foldable structure, large flow can be obtained at a low rotating speed, damage to cells in blood caused by too large rotating speed is reduced, the motor is externally arranged, and the temperature rise and fault risks of motor operation are effectively avoided. Meanwhile, an interventional artery passage is straight and short, abrasion and vibration of the shaft sleeve caused by bending of the flexible shaft are greatly reduced, power loss is reduced, power transmission efficiency is greatly improved, and controllability of the motor to the impeller and stability of power transmission are also improved.

The invention provides a ventricular auxiliary device for the right heart of a child, and belongs to the field of medical instruments. The problems that the flowing direction of accelerated blood is disordered, heat is still generated by friction, and thrombus is prone to being abraded after being used for a long time are solved. A ventricular auxiliary device for the right heart of a child comprises a rotor and a shell, the shell is in a hollow column shape with two open ends, magnet check blocks are arranged at the two ends of the shell, the rotor is assembled between the magnet check blocks, the rotor suspends between the two magnet check blocks through magnetic force, a second channel is formed in the middle of the magnet check blocks, and a first channel is formed in the middle of the rotor. The diameter of the first channel is the same as that of the second channel, the diameter of the magnet check block is the same as that of the rotor, and the rotor can be driven by in-vitro magnetic coupling driving equipment to rotate. The blood flow path is simplified, the change of the blood flow direction is reduced, the generated heat is further reduced, thrombus is prevented, and abrasion is reduced.

The utility model discloses a patent foramen ovale plugging device. The plugging device comprises a right heart plugging disc (1), a left heart plugging disc (2) and a connecting part (3), the right heart plugging disc is connected with the left heart plugging disc through the connecting part, and flow blocking films are arranged in the right heart plugging disc, the left heart plugging disc and the connecting part; the section of the connecting part is elliptical; the diameter of the left heart plugging disc is larger than that of the right heart plugging disc; the right heart plugging disc, the left heart plugging disc and the connecting part are formed by weaving elastic metal wires; the elastic metal wires are made of partially degradable materials or completely degradable materials. According to the plugging device, the cross section of the connecting part is oval, so that the plugging device can be better attached to the oval foramen of a patient, and a good plugging effect is achieved.

The invention discloses application of scopalactone in treatment of pulmonary arterial hypertension, and relates to the technical field of medicinal chemistry. The scoparone is applied to preparation of the medicine for treating pulmonary arterial hypertension. The medicine comprises scopalactone, a pharmaceutically acceptable carrier, a diluent and an excipient, the medicine further comprises other medicines for treating the pulmonary arterial hypertension, and the other medicines for treating the pulmonary arterial hypertension are selected from a prostacyclin medicine, an endothelin receptor antagonist and a phosphodiesterase-5 inhibitor. The scopalactone is applied to preparation of the medicine for treating pulmonary arterial hypertension, right heart insufficiency caused by hypoxia can be remarkably reversed, and the right heart function is effectively improved by reducing the transverse diameter of the right ventricle and the transverse diameter of the right atrium and improving the indexes such as tricuspid valve ring plane contraction displacement; the average pulmonary arterial pressure and right ventricular systolic pressure can be obviously reduced, and hemodynamic parameters are improved; the area and thickness of a blood vessel wall can be remarkably reduced, the blood vessel structure is improved, and pulmonary arteriole reconstruction is relieved.

This invention discloses a method for controlling left and right ventricular compression before extracorporeal circulation. First, in an in vitro environment, peristaltic pumps are installed at the left and right ventricular inlets of the extracorporeal circulation device. Then, an inlet pump is connected to the inlet of the peristaltic pumps, and an outlet pump is connected to the outlet of the peristaltic pumps. Finally, a first pressure measuring structure and a second pressure measuring structure are respectively installed on the side of the inlet and outlet pumps away from the peristaltic pumps, and the pressure of both the inlet and outlet pumps is adjusted to -180 mmHg. The negative pressure of the inlet pump is adjusted by the first pressure measuring structure, and the negative pressure of the outlet pump is adjusted by the second pressure measuring structure, thereby quantifying the adjustment method. This visualizes the process of controlling left and right ventricular compression before extracorporeal circulation, converting the adjustment results into specific negative pressure values ​​for the inlet and outlet pumps. This makes the reference values ​​for adjusting left and right ventricular compression numerically and standardized, avoiding adjustment discrepancies, eliminating reliance on experience and intuition, and providing a quick and highly accurate adjustment method.

The invention relates to the technical field of right heart acoustic radiography image analysis, in particular to a right heart acoustic radiography examination process standardization system. The method comprises the following steps: firstly, acquiring a multi-view dynamic ultrasonic image sequence of the right heart through ultrasonic equipment according to industrial standard operation specifications; then preprocessing the image sequence, extracting right heart function related data by adopting an image processing algorithm, and analyzing wall motion and left heart bubbles; acquiring a global anomaly recognition result through an anomaly recognition algorithm, and positioning an anomaly region by means of a YOLO algorithm and generating a local anomaly recognition result; and finally, the identification result and the metadata are transmitted to a display device for medical staff to check and analyze. In addition, encryption storage and access right control also ensure the security of the check data in the storage and transmission process. According to the method, the radiography data analysis speed and accuracy are improved, and then the right heart acoustic radiography image analysis quality and efficiency are improved.

An apparatus (100), system and method for automated execution of a bubble test. The apparatus (100) comprises a container (110) for accommodating normal saline, a pipeline (120), a first syringe (160), a second syringe (170), a first valve (130), a second valve (140), and a third valve (100). By using the apparatus (100) to perform the bubble test, the accuracy of the results of the bubble test can be improved while the time for the bubble test is shortened. When the apparatus (100) is used to perform a right heart contrast test, the apparatus (100) can automatically draw normal saline, blood, and air, and the preparation and injection of a contrast agent are automatically carried out by means of the repeated pushing and pulling of the first syringe (160) and the second syringe (170). When the apparatus (100) is used to perform a left heart contrast test, normal saline and a left heart contrast agent can be manually or automatically mixed, then the contrast agent is uniformly mixed by using a uniform mixing apparatus or the left heart contrast agent is uniformly mixed by means of the repeated pushing and pulling of the first syringe (160) and the second syringe (170), so as to form microbubbles, and finally, the microbubble contrast agent is injected into a human body. The apparatus (100) can be used to perform not only the right heart contrast test but also the left heart contrast test, thereby greatly improving the utilization rate of the apparatus.

The present invention discloses a positioning device and method for a right heart catheterization pressure measurement transducer, belonging to the inspection and pressure measurement of right heart catheters in the technical field of electrocardiogram detection. The purpose is to solve the technical problems of cumbersome positioning and low positioning accuracy existing in the zero-point positioning of existing transducers. It includes: a bed surface, a mounting frame, a lifting lead screw, an RFID reader, a lower RFID tag, and an upper RFID tag; the RFID reader emits radio frequency signals, and the lower RFID tag and the upper RFID tag are activated and return response signals after receiving the signals; the RFID reader receives the response signals and calculates the distances between the lower RFID tag and the RFID reader, and between the upper RFID tag and the RFID reader respectively according to the time from sending the radio frequency signal to receiving the response signal, and calculates and determines the position of the fixing frame based on the distances between the RFID reader, the lower RFID tag, and the upper RFID tag pairwise. The entire positioning process only requires placing the RFID reader, greatly simplifying the procedure for zero-point positioning of the transducer, making the positioning process more convenient and with high positioning accuracy.

The invention belongs to the technical field of biological medicine, and particularly relates to application of trametes robiniophila extract in preparation of medicine for preventing and treating pulmonary arterial hypertension. Research results show that the trametes robiniophila extract can effectively inhibit proliferation phenotypes of pulmonary artery smooth muscle cells, and can relieve phenotypes of pulmonary arterial hypertension modeling rats, including indexes such as right ventricular systolic pressure, right heart hypertrophy index and vascular remodeling degree. A new technical means is provided for treatment of pulmonary arterial hypertension, and the trametes robiniophila extract can be used for treatment of PH and has a good clinical transformation application prospect.

To provide a vehicular seat comprising an ottoman that can accurately obtain biological information on a seated occupant.SOLUTION: A vehicular seat 10B is provided with a seat body 11 and an ottoman 15 that can be displaced with respect to the seat body 11. The ottoman 15B is displaced between a storing position where the ottoman is stored below the seat body 11 and an expanding position where the ottoman extends toward a front side of the seat body 11, which has a left heartbeat sensor 152a that detects a heart rate of a left lower leg part of a seated occupant and a right heartbeat sensor 152b that detects a heart rate of a right lower leg part of the seated occupant, when the ottoman is positioned at the expanding position.SELECTED DRAWING: Figure 14

The invention relates to the technical field of medical equipment, and provides a right heart suction tube assembly. The right heart suction tube assembly comprises negative pressure equipment, a tube body, a diaphragm, a suction head, a first baffle and a second baffle. The tube body comprises a tube head end and a tube tail end; the interior of the tube body is divided into a first tube cavity and a second tube cavity by the diaphragm; the suction head is arranged at the tube head end; the first baffle is movably arranged in the first tube cavity, the first baffle comprises a first position and a second position, and when the right heart suction tube assembly works normally, the first baffle is located at the first position, and when the first baffle is located at the second position, the first baffle blocks the first tube cavity; the second baffle is movably arranged in the second tube cavity, the second baffle comprises a third position and a fourth position, and when the right heart suction tube assembly works normally, the second baffle is located at the third position, and when the second baffle is located at the fourth position, the second baffle blocks the second tube cavity. According to the right heart suction tube assembly, the phenomenon that the right heart suction tube assembly is completely blocked in an operation can be avoided.